Indian Journal of Nuclear Medicine最新文献_第2页

Solitary Renal Metastasis in Esophageal Squamous Cell Cancer Detected on F-18 FDG PET/CT - A Rare Presentation. F-18 FDG PET/CT检测食管鳞状细胞癌单发肾转移的罕见表现。

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Indian Journal of Nuclear Medicine Pub Date : 2025-01-01 Epub Date: 2025-05-16 DOI: 10.4103/ijnm.ijnm_96_24

Tanvi Sarwal, Althaf K Majeed, B Selvakumar, Vaibhav Kumar Varshney, Meenakshi Rao, Rajesh Kumar

引用次数: 0

A Perspective on Production and Quality Control of Iodine-123 Radiopharmaceutical for Applications in Nuclear Medicine. 核医学用放射性药物碘-123的生产与质量控制研究进展

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Indian Journal of Nuclear Medicine Pub Date : 2025-01-01 Epub Date: 2025-05-16 DOI: 10.4103/ijnm.ijnm_104_24

Rimmo Loyi Lego

{"title":"A Perspective on Production and Quality Control of Iodine-123 Radiopharmaceutical for Applications in Nuclear Medicine.","authors":"Rimmo Loyi Lego","doi":"10.4103/ijnm.ijnm_104_24","DOIUrl":"10.4103/ijnm.ijnm_104_24","url":null,"abstract":"The present work aims to provide a comprehensive analysis of the production methods for Iodine-123 (123I), with a particular focus on recent advances in nuclear medicine in India and relevant future perspectives. 123I, a radioisotope widely used in nuclear medicine for diagnostic imaging, plays a crucial role in the diagnosis and management of various medical conditions. It examines the historical background of 123I production and their importance in the medical field, emphasizing the recent breakthroughs in the field of nuclear chemistry and radiopharmaceuticals. This work also explores the challenges associated with the production of these isotopes, including their short half-lives and complex production routes. In addition, the report highlights emerging technologies and methodologies that have shown promise for more efficient and cost-effective production of 123I. Finally, the report provides an outlook on the future of radiopharmaceuticals (123I and beyond) production, including the potential impact of new advancements on clinical applications and research endeavors.","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"40 1","pages":"1-9"},"PeriodicalIF":0.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12121839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sentinel Lymph Node Detection in Early-stage Ovarian Cancer Using Radionuclide Technetium-99m Sulfur Colloid - A Feasibility Study. 放射性核素锝-99m硫胶体检测早期卵巢癌前哨淋巴结的可行性研究。

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Indian Journal of Nuclear Medicine Pub Date : 2025-01-01 Epub Date: 2025-05-16 DOI: 10.4103/ijnm.ijnm_149_24

Ayush Heda, Shalini Rajaram, Anupama Bahadur, Amrita Gaurav, Vandana Kumar Dhingra, Nilotpal Chowdhury, Manishi L Narayan, Jaya Chaturvedi, Parmita Tiwari, Pallavi Verma

{"title":"Sentinel Lymph Node Detection in Early-stage Ovarian Cancer Using Radionuclide Technetium-99m Sulfur Colloid - A Feasibility Study.","authors":"Ayush Heda, Shalini Rajaram, Anupama Bahadur, Amrita Gaurav, Vandana Kumar Dhingra, Nilotpal Chowdhury, Manishi L Narayan, Jaya Chaturvedi, Parmita Tiwari, Pallavi Verma","doi":"10.4103/ijnm.ijnm_149_24","DOIUrl":"10.4103/ijnm.ijnm_149_24","url":null,"abstract":"Purpose of the study: This study evaluates the feasibility and diagnostic accuracy of Tc-99 m sulfur colloid as a tracer for sentinel lymph node (SLN) mapping in early-stage epithelial ovarian cancer (EOC) with the aim to explore SLN mapping as a less invasive alternative to traditional lymphadenectomy.Materials and methods: This prospective observational study involved 10 patients with early-stage EOC or suspicious ovarian masses. Tc-99 m S colloid (37 mBq) was injected subperitoneally at infundibulopelvic and ovarian ligaments near the ovary, followed by SLN detection with a gamma probe. SLNs were analyzed using ultrastaging. Diagnostic accuracy metrics, including sensitivity, specificity, positive predictive value, and negative predictive value, were calculated.Results: SLN detection was achieved in 100% of cases, with detection rates of 10% in the pelvic region and 30% in the para-aortic region alone and in both in 60%. The time for SLN detection was 14.2 ± 4.89 min. Histopathology revealed isolated tumor cells in two cases, with no false negatives observed. Postoperative complications included surgical site infections, transfusions, and paralytic ileus, but no SLN-specific complications were reported.Conclusions: This study demonstrates the feasibility and diagnostic accuracy of SLN detection using technetium-99m sulfur colloid in early-stage ovarian cancer. The findings indicate a high detection rate, no false negatives, and the potential to reduce the need for systematic lymphadenectomy. Further research is required to validate these findings and evaluate their impact on long-term clinical outcomes.","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"40 1","pages":"16-21"},"PeriodicalIF":0.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12121844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Case of Early Visualization of Foregut Duplication Cyst in Meckel Scan. Meckel扫描早期发现前肠重复囊肿1例。

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Indian Journal of Nuclear Medicine Pub Date : 2024-11-01 Epub Date: 2025-03-20 DOI: 10.4103/ijnm.ijnm_153_23

Anushna S Babu, Dikhra Khan, Madhavi Tripathi, Rakesh Kumar

引用次数: 0

Heterotopic Pancreas Masquerading as Omental Nodule on FAPI PET/CT. 异位胰腺在FAPI PET/CT上伪装成大网膜结节。

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Indian Journal of Nuclear Medicine Pub Date : 2024-11-01 Epub Date: 2025-03-20 DOI: 10.4103/ijnm.ijnm_140_23

Shrikant Vasantrao Solav, Shailendra Vasant Savale, Hemant Bhagwan Raundale, Vijaykumar Revansidha Keskar

{"title":"Heterotopic Pancreas Masquerading as Omental Nodule on FAPI PET/CT.","authors":"Shrikant Vasantrao Solav, Shailendra Vasant Savale, Hemant Bhagwan Raundale, Vijaykumar Revansidha Keskar","doi":"10.4103/ijnm.ijnm_140_23","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_140_23","url":null,"abstract":"Chylous ascites, attributed to various etiologies including malignancy, tuberculosis, ruptured lymphatics, and congenital lymphatic disorders, manifests as abdominal distension. Our patient presented with this condition, and an elevated CA 125 prompted further investigation. Flourine-18 fluorodeoxyglucose positron emission tomography/computed tomography (PET-CT) revealed a metabolically inactive omental nodule, while gallium 68 fibroblast activation protein inhibitor (Ga-68-FAPI) PET-CT demonstrated uptake in the same nodule and low-grade uptake in bilateral adnexae. Colloid liver scan ruled out chronic liver disease. Surprisingly, lymphoscintigraphy showed no lymphatic leak. Histological examination of the omental nodule confirmed heterotopic pancreas (HP) in the small bowel mesentery, with normal adnexae. This case report illuminates the diagnostic challenges entailed in HP and signifies a pioneering instance in the literature where evidence of HP was identified for the first time on Ga-68-FAPI PET-CT during the investigative process.","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 6","pages":"441-444"},"PeriodicalIF":0.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inflammatory Mimicry: Epididymo-orchitis Masquerading as Malignancy on [18F]-FDG PET/CT Imaging. 炎性模拟：在[18F]-FDG PET/CT成像上伪装成恶性的附睾睾丸炎。

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Indian Journal of Nuclear Medicine Pub Date : 2024-11-01 Epub Date: 2025-03-20 DOI: 10.4103/ijnm.ijnm_92_24

Sharjeel Usmani, Anjali Jain, Khulood Al Riyami, Hajar Almarzouqi, Vipin Velangadi Jayakrishan, Subash Kheruka, Rashid Al Sukati

{"title":"Inflammatory Mimicry: Epididymo-orchitis Masquerading as Malignancy on [18F]-FDG PET/CT Imaging.","authors":"Sharjeel Usmani, Anjali Jain, Khulood Al Riyami, Hajar Almarzouqi, Vipin Velangadi Jayakrishan, Subash Kheruka, Rashid Al Sukati","doi":"10.4103/ijnm.ijnm_92_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_92_24","url":null,"abstract":"False positive findings in 18F-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET/CT) scans can present challenges in the accurate diagnosis and staging of various conditions. We report a case of a 52-year-old male with known adenocarcinoma of the stomach who underwent total gastrectomy and chemotherapy and was referred for 18F-FDG PET/CT to rule out recurrence. 18F-FDG PET/CT showed a large FDG-avid lesion involving the entire right testicle mimicking testicular cancer or lymphoma. Further evaluation with ultrasonography revealed epididymo-orchitis, possibly of granulomatous etiology. Orchitis, an inflammatory condition of the testicles, can cause misleading results in 18F-FDG PET/CT imaging for cancer surveillance. Imagers should cautiously interpret PET/CT findings, considering clinical context, patient history, and additional imaging modalities to distinguish true malignancies from false positives.","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 6","pages":"466-468"},"PeriodicalIF":0.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Uncommon Breast Odyssey: A Rare Case of Carcinoma Breast with Mesenteric Metastasis. 罕见的乳房奥德赛：一例罕见的乳腺癌合并肠系膜转移。

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Indian Journal of Nuclear Medicine Pub Date : 2024-11-01 Epub Date: 2025-03-20 DOI: 10.4103/ijnm.ijnm_5_24

Prakash Singh, Yogita Khandelwal, Kanishka Bharti, Shivam Singh

引用次数: 0

Testicular Tuberculosis after Intravesical BCG for Urinary Bladder Cancer: A Role of FDG PET-CT. 膀胱内卡介苗治疗膀胱癌后睾丸结核：FDG PET-CT的作用。

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Indian Journal of Nuclear Medicine Pub Date : 2024-11-01 Epub Date: 2025-03-20 DOI: 10.4103/ijnm.ijnm_115_24

R Arun Visakh, Senthil Raja, Thara Pratap, Renu Mariam Thomas, Vadavattathu Padmanabhan Gangadharan

引用次数: 0

Intriguing Encounter: Unveiling Squamous Cell Carcinoma Lung with Rare Bilateral Renal and Pituitary Metastasis on [18F]-FDG PET/CT. 有趣的相遇：在[18F]-FDG PET/CT上揭示肺鳞状细胞癌合并罕见的双侧肾和垂体转移。

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Indian Journal of Nuclear Medicine Pub Date : 2024-11-01 Epub Date: 2025-03-20 DOI: 10.4103/ijnm.ijnm_57_24

Prakash Singh, Yogita Khandelwal, Vineet Mishra, Bela Jain

{"title":"Intriguing Encounter: Unveiling Squamous Cell Carcinoma Lung with Rare Bilateral Renal and Pituitary Metastasis on [18F]-FDG PET/CT.","authors":"Prakash Singh, Yogita Khandelwal, Vineet Mishra, Bela Jain","doi":"10.4103/ijnm.ijnm_57_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_57_24","url":null,"abstract":"Metastases from squamous cell carcinoma of the lung typically occur in the brain, liver, adrenal glands, bone, and regional lymph nodes. It is exceedingly uncommon to encounter multiple rare sites of metastasis from a single primary neoplasm. Herein, we describe a case of a 44-year-old male diagnosed with squamous cell carcinoma lung with pituitary and renal metastasis detected on 18F-FDG (Fluorodeoxyglucose) PET/CT. 18F-FDG PET/CT is the standard of care and is an integral part of the clinical staging of patients with lung cancer. According to published literature, the incidence of symptomatic pituitary and renal metastasis from squamous cell carcinoma lung is rare to find with incidences <1% and 5%, respectively. The revelation of rare sites of metastasis originating from primary squamous cell carcinoma lung, as reported in this case on FDG PET/CT, illuminates the exceptional rarity and intricacies in oncology. The exquisite sensitivity of FDG PET/CT enables the identification of occult metastasis in atypical anatomical locations, presenting a distinct advantage over conventional imaging modalities.","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 6","pages":"454-456"},"PeriodicalIF":0.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancing Nuclear Medicine through Discovery, Invention, and Innovation - Contribution of a Physicist and Scientist (Vikram Sarabhai Memorial Oration-2023). 通过发现、发明和创新推进核医学——物理学家和科学家的贡献（Vikram Sarabhai纪念演讲-2023）。

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Indian Journal of Nuclear Medicine Pub Date : 2024-11-01 Epub Date: 2025-03-20 DOI: 10.4103/ijnm.ijnm_118_24

Ashish Kumar Jha

{"title":"Advancing Nuclear Medicine through Discovery, Invention, and Innovation - Contribution of a Physicist and Scientist (Vikram Sarabhai Memorial Oration-2023).","authors":"Ashish Kumar Jha","doi":"10.4103/ijnm.ijnm_118_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_118_24","url":null,"abstract":"The history of radiation science began with Wilhelm Rontgen's discovery of X-rays in 1895, followed closely by Henri Becquerel's discovery of radioactivity in 1896. Subsequent research focused on developing radioisotope technology and exploring its applications in medical diagnosis and treatment. The first recorded use of radioisotopes for tumor treatment was by William Dune in Marie Curie's laboratory. George D Heawse employed radioisotopes to study plant and animal physiology. Irene and Joliot Curie pioneered the production of artificial radioisotopes using alpha particle bombardment. Ernest O. Lawrence's invention of the cyclotron furthered the development of artificial isotopes. His brother John Lawrence treated the first patient with cyclotron-produced phosphorus-32. Glenn Seaborg's discovery of Tc-99m and I-131 led to the development of radioiodine therapy by Saul Hertz and many diagnostic procedures using Tc-99m. Bendit Casin invented the rectilinear scanner, a pioneering imaging device, while Hal Anger developed the gamma camera. Over time, the contributions of researchers, scientists, engineers, and physicians have advanced the field of nuclear medicine, resulting in state-of-the-art equipment such as positron emission tomography (PET)/magnetic resonance imaging (MRI), positron emission tomography (PET)/computed tomography (CT), single-photon emission computed tomography (SPECT)/computed tomography (CT), and many other innovative technologies.","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 6","pages":"421-427"},"PeriodicalIF":0.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0