Indian Journal of Nuclear Medicine最新文献

{"title":"Detection of Docetaxel-induced Interstitial Pneumonitis on Ga-68 PSMA PET/CT Imaging.","authors":"Anjali Meena, Bhagwant Rai Mittal, Harmandeep Singh, Girdhar S Bora, Rajender Kumar","doi":"10.4103/ijnm.ijnm_147_23","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_147_23","url":null,"abstract":"<p><p>Ga-68 labeled prostate-specific membrane antigen (PSMA) positron emission tomography-computed tomography (PET/CT) is increasingly recognized as the best imaging modality for disease staging and detection of recurrent prostate cancer. Despite its name, PSMA expression has been reported in the neovasculature of several nonprostatic benign and malignant pathologies. Docetaxel, a taxane antineoplastic agent, is the mainstay of treatment in castration-resistant prostate cancer and high-volume hormone-sensitive prostate cancer. Although the occurrence of docetaxel-related interstitial lung disease is rare, it may lead to respiratory failure if treatment is delayed. We present a case of metastatic castration-resistant prostate cancer, wherein docetaxel-induced interstitial pneumonitis was detected on Ga-68 PSMA PET/CT after docetaxel administration.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 3","pages":"220-221"},"PeriodicalIF":0.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404741/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spectrum of [18F]FDG PET/CT Findings in Primary Central Nervous System Lymphoma - A Pictorial Essay.","authors":"V Nithya, N C Valaiyapathy, Dhamarcherla S Hemalatha, Rallapeta Ramya Priya, D Bhargavi, Tekchand Kalawat","doi":"10.4103/ijnm.ijnm_21_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_21_24","url":null,"abstract":"<p><p>Primary central nervous system lymphoma (PCNSL) is a rare, aggressive variant of extranodal non-Hodgkin's lymphoma. Although gadolinium-enhanced magnetic resonance imaging remains the initial imaging modality of choice, a whole-body F-18 fluorodeoxyglucose (FDG) positron emission tomography-computed tomography is imperative to exclude systemic lymphomatous involvement. Furthermore, the metabolic parameter, maximum standardized uptake value (SUV_max) of the lesion, tumor-to-normal cerebral tissue SUV_max ratio, and FDG uptake patterns help in differentiating intracranial lymphomas from High-grade Glioblastoma Multiforme (HGM) and infectious lesions, and hence, consolidating the diagnosis. In this pictorial essay, we present a series of PCNSL cases, representing the different imaging characteristics and metabolic uptake patterns.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 3","pages":"191-197"},"PeriodicalIF":0.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term Side Effect of COVID-19 Infection; Osteonecrosis of the Femoral Head in SPECT/CT Bone Scintigraphy.","authors":"Mahdi Haghighatafshar","doi":"10.4103/ijnm.ijnm_19_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_19_24","url":null,"abstract":"<p><p>Avascular necrosis (AVN) of the femoral head is a condition characterized by limited mobility, discomfort, and changes in walking patterns due to insufficient blood supply in this region. Our objective is to investigate the possible connection between COVID-19 and AVN. In this study, we detail the case of a 41-year-old male patient who developed AVN in both femoral heads after contracting COVID-19. The mere occurrence of a COVID-19 infection and the use of corticosteroids for its treatment may increase the probability of AVN in the femoral head. Hence, post the COVID-19 pandemic, it is crucial to consider AVN vigilantly for timely detection and treatment.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 3","pages":"207-209"},"PeriodicalIF":0.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404732/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Analysis of the Diagnostic Performance of Tc-99m PSMA SSPECT/CT in Biochemically Recurrent Prostate Cancer Compared with Ga-68 PSMA PET/CT: A Single-center, Prospective Study.","authors":"Manish Ora, Vivek Kumar Saini, Manish Dixit, Uday Pratap Singh, Sanjay Gambhir","doi":"10.4103/ijnm.ijnm_8_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_8_24","url":null,"abstract":"<p><strong>Objective: </strong>Biochemical recurrence (BCR) after initial management of Prostate Carcinoma (PC) is frequent. Subsequent interventions rely on disease burden and metastasis distribution. ⁶⁸Ga prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) is an excellent imaging modality in BCR. However, ⁶⁸Ga is radionuclide generator produced and has restricted availability. ⁹⁹mTc-labeled PSMA could be a potential cost-effective alternative. We compared the performance of ^99mTc-PSMA single-photon emission CT (SPECT)/CT and ⁶⁸Ga-PSMA PET/CT in BCR with a serum prostate surface antigen (PSA) level of <20 ng/mL.</p><p><strong>Materials and methods: </strong>The prospective study included 25 patients with BCR and at least one lesion on a ⁶⁸Ga-PSMA PET/CT. All patients underwent 99 mTc-PSMA SPECT/CT, and disease distribution and metastatic burden were compared with ⁶⁸Ga-PSMA PET/CT. The maximum standard uptake value (SUVmax) and the tumor-to-background ratio (TBR) were computed and analyzed.</p><p><strong>Results: </strong>The mean age and serum PSA (SPSA) were 69.72 ± 6.69 years and 5.65 ± 6.07 ng/mL. Eleven patients (44%) had SPSA ≤2 ng/mL. Recurrent sites were noted in the prostate (19, 76%), prostatic bed (3, 12%), and pelvis lymph nodes (LNs) (13, 52%). Distant metastasis to bones (13, 52%), lungs (5, 20%), and retroperitoneal LNs (2, 8%) were noted. Both modalities were concordant for the recurrent disease at the prostate, prostatic bed, bone, and lung lesions. ^99mTc-PSMA could localize pelvis LNs in most patients (10/13, 76.9%). The site-specific sensitivity and specificity between the two modalities were not significantly different (<i>P</i> > 0.05). TBR shows excellent correlation with SUVmax (0.783, <i>P</i> < 0.001). Four (16%) patients were understaged with ^99mTc-PSMA due to the nonvisualization of the subcentimeter size LNs. No patient with systemic metastases was understaged.</p><p><strong>Conclusions: </strong>^99mTc-PSMA SPECT/CT has good concordance with ⁶⁸Ga-PSMA PET/CT in BCR, even at low PSA levels. However, it may miss a few subcentimeter LNs due to lower resolution. ^99mTc-PSMA SPECT/CT could be a simple, cost-effective, and readily available imaging alternative to PET/CT.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 3","pages":"170-176"},"PeriodicalIF":0.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tc-99m UBI Scintigraphy as a Cost-effective Alternative to Ga-68 NOTA-UBI PET/CT for Imaging Infections.","authors":"Satya Dev Maurya, Sanjana Ballal, Nishikant Avinash Damle, Varsha Tiwari, Chandra Sekhar Bal","doi":"10.4103/ijnm.ijnm_16_23","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_16_23","url":null,"abstract":"","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 3","pages":"237-238"},"PeriodicalIF":0.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular Imaging for Breast Cancer Phenotyping: Tc-99m sestamibi Scintigraphy cannot be Missed.","authors":"Luca Filippi, Antonio Rosario Pisani, Giuseppe Rubini","doi":"10.4103/ijnm.ijnm_33_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_33_24","url":null,"abstract":"","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 3","pages":"239-240"},"PeriodicalIF":0.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404742/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delusory Radioiodine Uptake in Endometriotic Ovarian Cyst.","authors":"Farinaz Farhoudi","doi":"10.4103/ijnm.ijnm_24_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_24_24","url":null,"abstract":"<p><p>A 25-year-old woman with a known case of papillary thyroid carcinoma conventional type referred to our center for treatment with radioactive iodine after total thyroidectomy. She received 200 mCi of radioiodine, and in the whole-body scan 1 week after the radioiodine therapy, an area of increased absorption was seen on the right side of the pelvis, which was diagnosed as an endometriotic ovarian cyst in the follow-up examinations.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 3","pages":"210-212"},"PeriodicalIF":0.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Interesting Image of Carcinoma Breast with Renal Calyceal Diverticulum Mimicking Renal Metastasis on [18F]FDG PET/CT Scan.","authors":"Surekha Bukke, Surya Gavini, Rallapeta Ramya Priya, S Hemalatha Dhamarcherla, Bodagala Vijalakshmi Devi, Tekchand Kalawat","doi":"10.4103/ijnm.ijnm_25_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_25_24","url":null,"abstract":"<p><p>A diverticulum is an outpouching of a hollow (or fluid-filled) structure in the body. They are most commonly seen in the urinary bladder, intestine, and pharyngeal region and are rarely seen in renal calyces. They are usually benign, asymptomatic, and are coincidentally detected. Due to their nonspecific clinical and radiological picture, sometimes they mimic malignant tumors, leading to misdiagnosis and treatment. We are presenting a case of 60-year-old female with right breast carcinoma, on whole body 18-fluorodeoxyglucose positron emission tomography-computed tomography; we observed an interesting finding in the right renal region mimicking renal metastasis.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 3","pages":"227-228"},"PeriodicalIF":0.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404731/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges of Using ChatGPT in Nuclear Medicine Academic Writing.","authors":"Arosh S Perera Molligoda Arachchige","doi":"10.4103/ijnm.ijnm_136_23","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_136_23","url":null,"abstract":"","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 3","pages":"236"},"PeriodicalIF":0.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404740/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum: <i>Institutional Experience of Routine Radiation Surveillance of Delay and Decay Tanks Facility in a Department Having High-dose Iodine Therapy Unit</i>.","authors":"","doi":"10.4103/ijnm.ijnm_111_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_111_24","url":null,"abstract":"<p><p>[This corrects the article on p. 83 in vol. 39, PMID: 38989319.].</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 3","pages":"241"},"PeriodicalIF":0.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}