Salah Nabih Oueriagli, Omar Ait Sahel, Yassir Benameur, Abderrahim Doudouh
{"title":"An Interesting Case of Sister Mary Joseph's Nodule Revealed by <sup>18</sup>F-FDG PET.","authors":"Salah Nabih Oueriagli, Omar Ait Sahel, Yassir Benameur, Abderrahim Doudouh","doi":"10.4103/ijnm.ijnm_34_25","DOIUrl":null,"url":null,"abstract":"<p><p>The Sister Mary Joseph's nodule is a rare umbilical metastatic lesion, occurring in 1%-3% of abdominopelvic adenocarcinomas. It represents the visible tip of the iceberg, and its presence is associated with a poor prognosis. We report the case of a 61-year-old postmenopausal female patient with rectosigmoid adenocarcinoma. An <sup>18</sup>F-fluorodeoxyglucose positron emission tomography/computed tomography (<sup>18</sup>F-FDG PET) scan revealed, in addition to a large sigmoid mass, multiple hypermetabolic lumbo-aortic lymphadenopathies, secondary hypermetabolic pulmonary and hepatic nodules, and a large subcutaneous umbilical nodule consistent with a Sister Marie Joseph's nodule. This case supports the systematic use of <sup>18</sup>F-FDG PET in oncologic evaluations involving suspicious umbilical nodules.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"40 4","pages":"263-264"},"PeriodicalIF":0.5000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12503169/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Nuclear Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/ijnm.ijnm_34_25","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/19 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
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Abstract
The Sister Mary Joseph's nodule is a rare umbilical metastatic lesion, occurring in 1%-3% of abdominopelvic adenocarcinomas. It represents the visible tip of the iceberg, and its presence is associated with a poor prognosis. We report the case of a 61-year-old postmenopausal female patient with rectosigmoid adenocarcinoma. An 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET) scan revealed, in addition to a large sigmoid mass, multiple hypermetabolic lumbo-aortic lymphadenopathies, secondary hypermetabolic pulmonary and hepatic nodules, and a large subcutaneous umbilical nodule consistent with a Sister Marie Joseph's nodule. This case supports the systematic use of 18F-FDG PET in oncologic evaluations involving suspicious umbilical nodules.
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