{"title":"Optical coherence tomography angiography findings in newly diagnosed hypertension patients with 24-h ambulatory blood pressure monitoring.","authors":"Cansu Sipal Kabayel, Bengi Ece Kurtul, Alparslan Kurtul","doi":"10.4103/tjo.TJO-D-25-00162","DOIUrl":"10.4103/tjo.TJO-D-25-00162","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effect of systemic arterial hypertension in newly diagnosed hypertensive patients using optical coherence tomography angiography (OCTA) parameters and to investigate whether an association exists between nondipper patterns confirmed by ambulatory blood pressure monitoring (ABPM) and OCTA measurements.</p><p><strong>Materials and methods: </strong>Forty-five healthy control patients without hypertension and 90 newly diagnosed hypertension patients were divided into two groups as dipper group (>10% nocturnal blood pressure [BP] fall) and nondipper group (≤10% nocturnal BP fall) according to their nocturnal BP reduction were included to the study. All patients underwent detailed ophthalmological examinations. Retinal and optic disc OCTA findings and ABPM data were obtained prospectively. The vessel density (VD) of the retinal superficial capillary plexus (SCP), deep capillary plexus, foveal retinal thickness, radial peripapillary capillary, and retinal nerve fiber layer (RNFL) thickness were compared between the groups.</p><p><strong>Results: </strong>The superior quadrant RNFL thickness was significantly lower in both the nondipper and dipper groups than in the control group (<i>P</i> = 0.014). However, the nondipper group showed a statistically significant increase in optic disc peripapillary capillary VD compared to the dipper and control groups (<i>P</i> = 0.018). SCP whole and perifoveal VD were significantly lower in the dipper and nondipper groups than in the control group (<i>P</i> = 0.011 and <i>P</i> = 0.008, respectively).</p><p><strong>Conclusion: </strong>Our data suggest an association between nondipper BP pattern and increased optic disc peripapillary VD, as well as lower levels of superior quadrant RNFL thickness. OCTA may be a useful marker for identifying retinal microvascular changes in newly diagnosed hypertensive patients.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"16 3","pages":"458-464"},"PeriodicalIF":1.4,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13668178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anisometropia in children: Current understanding and clinical implications.","authors":"Chia-Wei Lee, Yu-Chieh Yang, Hsin-Yu Yang, Chiao-Yu Wang, Shih-Hwa Chiou, Der-Chong Tsai","doi":"10.4103/tjo.TJO-D-25-00135","DOIUrl":"10.4103/tjo.TJO-D-25-00135","url":null,"abstract":"<p><p>Anisometropia in children, defined as an interocular refractive difference of at least 1.0 diopter, is a major risk factor for unilateral amblyopia and a significant disruptor of binocular vision. The underlying structural cause is typically asymmetric axial growth, reflecting a breakdown in the normally coordinated process of emmetropization. This narrative review summarizes current evidence on its epidemiology, pathophysiology, associated factors, and management. The condition follows a dynamic age-related pattern: it is prevalent in infancy, declines during early childhood as emmetropization progresses, and rises again during school years and adolescence in parallel with increasing rates of myopia. Genetic predisposition, altered visual feedback, and environmental exposures have been implicated. Reported associated factors include high baseline refractive error, short working distance during near tasks, ocular dominance, and unilateral conditions such as congenital nasolacrimal duct obstruction. Hyperopic anisometropia is particularly amblyogenic because of its early onset and persistent blur. Management centers on prompt optical correction above amblyogenic thresholds to balance visual input, combined with amblyopia therapy when required. In myopic anisometropia, evidence-based myopia-control strategies, such as topical atropine, orthokeratology, and specialized spectacle designs, play an important role in slowing progression and reducing interocular differences. Pediatric anisometropia is both a clinical challenge and a valuable model for studying refractive development. Future longitudinal studies are needed to clarify mechanisms and optimize preventive and therapeutic strategies.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"16 2","pages":"256-266"},"PeriodicalIF":1.4,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13431224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Combined central retinal and posterior ciliary artery occlusion in a young female with primary myelofibrosis and Sweet's syndrome: A case report.","authors":"Vikas Ambiya, Srishti Khullar, Gaurav Kapoor","doi":"10.4103/tjo.TJO-D-25-00176","DOIUrl":"10.4103/tjo.TJO-D-25-00176","url":null,"abstract":"<p><p>Primary myelofibrosis (PMF) is a rare myeloproliferative neoplasm that typically affects older adults but may present aggressively in younger patients. Thromboembolic complications are well recognized, though arterial occlusions are uncommon in this age group. Ocular ischemia associated with systemic inflammatory conditions such as Sweet's syndrome is exceedingly rare. A 22-year-old female with PMF, diagnosed 18 months earlier and managed initially with ruxolitinib, presented with sudden, complete loss of vision in her left eye. She also had a history of Sweet's syndrome managed with oral corticosteroids and had received multiple blood transfusions. Ophthalmic evaluation revealed no light perception in the left eye, a pale retina with attenuated vessels, and a cherry-red spot. Optical coherence tomography (OCT) showed hyperreflectivity of the inner retinal layers, and OCT angiography demonstrated markedly reduced perfusion in all vascular plexuses. Carotid Doppler, echocardiography, and ECG excluded embolic sources. Despite ocular massage, anterior chamber paracentesis, acetazolamide, and anticoagulation with apixaban, vision did not recover. One week later, she developed anterior uveitis, keratic precipitates, and elevated intraocular pressure. Fundus showed Amalric's sign of choroidal infarction and Elschnig spots, confirmed on fluorescein angiography. Inflammation responded to topical and systemic corticosteroids, with normalization of intraocular pressure. This is the first documented case of combined central retinal artery occlusion and posterior ciliary artery occlusion with anterior uveitis in a young PMF patient with Sweet's syndrome. The case underscores the multifactorial contribution of hypercoagulability, systemic inflammation, and transfusion-related factors in ocular ischemia.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"16 3","pages":"504-508"},"PeriodicalIF":1.4,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13668167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149197025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mark Yu Zheng Wong, Haoran Cheng, Leila Sara Eppenberger, Joey Chung Zi Ying, Angeline Toh, Marcus Ang
{"title":"Role of artificial intelligence in optical coherence tomography in myopia and pathological myopia.","authors":"Mark Yu Zheng Wong, Haoran Cheng, Leila Sara Eppenberger, Joey Chung Zi Ying, Angeline Toh, Marcus Ang","doi":"10.4103/tjo.TJO-D-25-00093","DOIUrl":"10.4103/tjo.TJO-D-25-00093","url":null,"abstract":"<p><p>Myopia and pathological myopia (PM) have been recognized as one of the leading causes of visual impairment globally. Optical coherence tomography (OCT) provides high-resolution imaging of retinal and choroidal structural changes and plays an increasing role in the diagnosis and prognostication of PM and myopia-related complications. Recent advances in OCT technology have produced a potential platform for artificial intelligence (AI), particularly deep learning (DL), to enhance diagnostic accuracy and prognostic capabilities. First, AI-assisted detection of myopia based on OCT-derived biomarkers such as retinal curvature, optic nerve morphology, and inner retinal thinning have the potential to detect high myopia. However, precise refractive error estimation or differentiation of lower-grade myopia remains modest. Future integration of OCT angiography may refine the prediction of myopia progression. Second, AI may improve automated segmentation and quantification of the choroid, with DL algorithms consistently delineating choroidal boundaries and quantifying region-specific choroidal thicknesses. Recent algorithms have extended beyond basic segmentation to choroidal sublayer segmentation and calculating choroidal vascularity indices, enhancing structural characterization in myopic eyes. Third, AI methods have advanced the detection of PM-related OCT lesions, reliably identifying critical lesions including myopic traction maculopathy, myopic choroidal neovascularization, and dome-shaped macula. Recent models have also shown the ability to categorize disease severity according to validated clinical frameworks, such as the Atrophy-Traction-Neovascularization and myopic tractional maculopathy staging systems. Despite these advances, current AI methods face challenges including inconsistent OCT protocols, limited longitudinal data, inadequate external validation, and difficulties handling poor-quality scans. Addressing these limitations could facilitate clinical integration, enhancing early diagnosis, prognostication, and possibly, personalized myopia management in the future.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"16 2","pages":"212-227"},"PeriodicalIF":1.4,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13431222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The new horizon of ophthalmic plastic and reconstructive surgery - From digital intelligence to precision intervention.","authors":"Kyung In Woo","doi":"10.4103/tjo.TJO-D-26-00003","DOIUrl":"10.4103/tjo.TJO-D-26-00003","url":null,"abstract":"","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"16 1","pages":"1-2"},"PeriodicalIF":1.4,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jessica Y Tong, Jeffrey Sung, Wiliam Machado de Andrade, WengOnn Chan, Alkis J Psaltis, Dinesh Selva
{"title":"An oculoplastic perspective on Transorbital Neuroendoscopic Surgery: Anatomical corridors and clinical applications.","authors":"Jessica Y Tong, Jeffrey Sung, Wiliam Machado de Andrade, WengOnn Chan, Alkis J Psaltis, Dinesh Selva","doi":"10.4103/tjo.TJO-D-25-00171","DOIUrl":"10.4103/tjo.TJO-D-25-00171","url":null,"abstract":"<p><p>Transorbital neuroendoscopic surgery (TONES) has adopted an increasingly prominent role as a minimally invasive technique for the management of orbitocranial pathology. It can be applied to a range of conditions, from intraorbital lesions to complex tumors that cross the boundaries between the orbit and cranial fossa. The primary approaches include the superior lid crease incision and lateral retrocanthal incisions, with other alternatives including the precaruncular and inferior transconjunctival approaches. This review will examine the role of the oculoplastic surgeon in multidisciplinary TONES procedures. Cadaveric and clinical studies have defined anatomical corridors and demonstrated the technical feasibility and functional outcomes of providing access to the anterior and middle cranial fossae. Adjunctive maneuvers, such as a lateral orbitotomy or creation of extra-orbital portals, can be performed to improve surgical freedom and access. The choice of technique can be tailored to the type and location of pathology and surgical objectives regarding diagnosis and resection.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"16 1","pages":"26-34"},"PeriodicalIF":1.4,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147699922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dacryoendoscopy: Historical development, philosophical foundation, and clinical perspective.","authors":"Toru Suzuki, Tomoyuki Kamao, Jutaro Nakamura, Akemi Iwasaki, Nozomi Matsumura","doi":"10.4103/tjo.TJO-D-25-00167","DOIUrl":"10.4103/tjo.TJO-D-25-00167","url":null,"abstract":"<p><p>Dacryoendoscopy is valuable for managing epiphora, enabling direct visualization of the lacrimal outflow system. Notably, dacryoendoscopy enhances diagnostic precision and facilitates minimally invasive treatment. Over the past three decades, its evolution has fostered a deeper understanding of endoluminal pathology, refined recanalization techniques, and expanded therapeutic indications across age groups. Importantly, dacryoendoscopy represents not only technical refinement but also a conceptual shift - from blind intervention to anatomy-based diagnosis and management. This shift reflects a deeper surgical philosophy, that visualization must precede intervention, and that humility toward unseen structures is crucial for true minimally invasive practice. This narrative review explores the device design philosophy, terminology, and clinical use of dacryoendoscopy, focusing on the Bent group's contributions and the emergence of conservative minimally invasive lacrimal surgery, which emphasizes mucosal preservation and is specifically suited for pediatric cases. The Bent probe endoscopes, originating in Japan, have become the most widely used devices in Asia. Moreover, false passage was illustrated in relation to the duct lumen remnant within fibrous blockage, and key techniques, including sheath-guided endoscopic probing and sheath-guided intubation, were reviewed. Regardless of these advances, challenges such as long-term deterioration of surgical outcomes and the distant goal of mucosal regeneration persist. Relevant literature was identified through a nonsystematic search of PubMed and Ichushi-Web, using the keywords \"dacryoendoscopy,\" \"nasolacrimal duct,\" and \"false passage,\" covering publications from 1995 to 2025.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"16 1","pages":"44-57"},"PeriodicalIF":1.4,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epidemiology and follow-up adherence of ophthalmic emergencies: A 10-year study at a tertiary medical center in Taiwan.","authors":"Tsung-Ying Tsai, Chunya Kang, Laura Liu, Nan-Kai Wang, Kuan-Jen Chen, Wei-Chi Wu, Chi-Chun Lai, Sunir J Garg, Eugene Yu-Chuan Kang, Yih-Shiou Hwang","doi":"10.4103/tjo.TJO-D-25-00134","DOIUrl":"10.4103/tjo.TJO-D-25-00134","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of the study was to evaluate factors influencing outpatient follow-up adherence among patients receiving ophthalmology consultations in the emergency department (ED).</p><p><strong>Materials and methods: </strong>This retrospective cohort study collected data from the Chang Gung Research Database. Patients who received ophthalmology consultations at the ED of Chang Gung Memorial Hospital Linkou Medical Center from January 1, 2010, to December 31, 2019, were included. Patients were divided into two groups based on whether they completed outpatient follow-up within 28 days, a timeframe consistent with our hospital's scheduling policy. Demographics, ED visit timing, triage categories, ophthalmic diagnoses, prior visits, and ED stay durations were analyzed using logistic regression.</p><p><strong>Results: </strong>A total of 42,530 patients were included (mean age 38.6 ± 20.2 years; 59.2% male), with 38.4% adhering to follow-up and 61.6% not. Nonadherence was associated with younger age (odds ratio [OR]: 0.92; 95% confidence interval [CI]: 0.92-0.93), evening (OR: 1.28; 95% CI: 1.22-1.34) or midnight (OR: 1.94; 95% CI: 1.83-2.06) ED visits, not likely emergent diagnoses (OR: 2.09; 95% CI: 1.96-2.22), and shorter ED stays (<1 h: OR: 3.73; 95% CI: 3.46-4.03). Patients with prior ophthalmology outpatient visits (OR: 0.48; 95% CI: 0.46-0.52) and longer ED stays (more than 3 h) demonstrated better adherence. Over 10 years, emergent diagnoses increased from 51.1% to 69.5%, while non-emergent diagnoses declined from 23.1% to 13.2%.</p><p><strong>Conclusion: </strong>Adherence to outpatient follow-up after ophthalmic ED visits was low. Younger age, evening or midnight visits, non-emergent diagnoses, and short ED stays predicted non-adherence, whereas prior outpatient visits and longer ED stays improved adherence.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"16 1","pages":"114-124"},"PeriodicalIF":1.4,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patient-specific implants for orbital fracture surgery.","authors":"Min Kyu Yang, Ho-Seok Sa","doi":"10.4103/tjo.TJO-D-25-00152","DOIUrl":"10.4103/tjo.TJO-D-25-00152","url":null,"abstract":"<p><p>Orbital wall fractures are among the most common maxillofacial injuries and require precise reconstruction to restore orbital volume, prevent diplopia, and avoid long-term sequelae such as enophthalmos or facial asymmetry. Traditional reconstruction techniques have relied on autologous grafts and preformed alloplastic implants; however, these approaches are limited by intraoperative variability, imprecise contour restoration, and increased operative time. Over the past decade, the emergence of patient-specific implants (PSIs), designed through advanced three-dimensional (3D) imaging, computer-aided design, and computer-aided manufacturing, has transformed the field of orbital reconstruction. PSIs allow highly accurate anatomical restoration, reduce intraoperative manipulation, and improve clinical outcomes. This review provides a comprehensive overview of the evolution of orbital fracture reconstruction, design and fabrication principles of PSIs, clinical evidence supporting their use, limitations, and future directions, including bioactive materials, artificial intelligence-driven design, and point-of-care 3D printing.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"16 1","pages":"35-43"},"PeriodicalIF":1.4,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From pixels to precision: Imaging technologies shaping oculofacial plastic surgery practice.","authors":"Anne Xuan-Lan Nguyen, Merve Kulbay, Albert Y Wu","doi":"10.4103/tjo.TJO-D-25-00141","DOIUrl":"10.4103/tjo.TJO-D-25-00141","url":null,"abstract":"<p><p>Recent advances in imaging technologies have transformed surgical practice, enabling more accurate diagnoses, refined perioperative planning, and improved patient outcomes. In oculofacial plastic surgery, these tools provide safer and more precise alternatives to traditional approaches, which often relied on invasive exploration or standard imaging with limited accuracy. This review summarizes the current state of imaging technologies in oculofacial plastic surgery and discusses their benefits, limitations, and challenges. Key developments include: (i) Endoscopic imaging, providing high-resolution, magnified visualization for minimally invasive procedures, particularly in lacrimal and orbital surgery, (ii) Exoscopic imaging, a 4K-three-dimensional (3D) external system enhancing precision and team collaboration in microsurgery, (iii) Magnetic resonance imaging offering detailed 3D images of internal structures, with emerging 7T systems providing higher resolution and improved tissue contrast, (iv) Stereotactic navigation, integrating preoperative imaging with real-time tracking to guide complex orbital procedures and fracture repairs, (v) Artificial intelligence-based imaging tools, including machine learning models for disease detection, surgical planning, and outcome prediction, as well as text-to-image systems for preoperative patient counseling. Together, these technologies reduce operative risk, improve functional and esthetic outcomes, and enable patient-specific approaches. Despite challenges such as cost, accessibility, technical limitations, and learning curves, the integration of advanced imaging is steering oculofacial plastic surgery toward minimally invasive, data-driven, and patient-centered practice.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"16 1","pages":"11-20"},"PeriodicalIF":1.4,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}