Taiwan Journal of Ophthalmology最新文献

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Pigmented versus nonpigmented ocular surface squamous neoplasia: A comparative study of 424 tumors. 色素性与非色素性眼表鳞状瘤变:424例肿瘤的比较研究。
IF 1.2
Taiwan Journal of Ophthalmology Pub Date : 2025-10-28 eCollection Date: 2026-01-01 DOI: 10.4103/tjo.TJO-D-24-00148
Kavya Madhuri Bejjanki, Vijitha S Vempuluru, Anasua Ganguly Kapoor, Swathi Kaliki
{"title":"Pigmented versus nonpigmented ocular surface squamous neoplasia: A comparative study of 424 tumors.","authors":"Kavya Madhuri Bejjanki, Vijitha S Vempuluru, Anasua Ganguly Kapoor, Swathi Kaliki","doi":"10.4103/tjo.TJO-D-24-00148","DOIUrl":"https://doi.org/10.4103/tjo.TJO-D-24-00148","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to compare the clinical features, management, and outcomes of patients with pigmented ocular surface squamous neoplasia (p-OSSN) versus nonpigmented OSSN (np-OSSN).</p><p><strong>Materials and methods: </strong>This was a retrospective, comparative, interventional study.</p><p><strong>Results: </strong>Of 424 tumors in 414 patients, 194 were np-OSSN, and 230 were p-OSSN. The mean age at presentation of np-OSSN versus p-OSSN was 53 years (median, 55 years; range, 12-88 years) versus 50 years (50 years, 20-85 years). The statistically significant differences between np-OSSN vs p-OSSN included outdoor occupation (<i>n</i>=77 (40%) vs <i>n</i>=120 (54%); <i>P</i>=0.006), limbal tumor epicenter (<i>n</i>=98 (50%) vs <i>n</i>=153 (67%); <i>P</i><0.001), diffuse tumor configuration (<i>n</i>=23 (12%) vs <i>n</i>=6 (3%); <i>P</i><0.001), and association with complexion-associated melanosis (CAM) (<i>n</i>=40 (21%) vs <i>n</i>=187 (81%); <i>P</i><0.001). The mean % of tumor pigmentation in p-OSSN was 43% (median, 35%; range, 1%-100%). The most common histopathological variant was moderate dysplasia in p-OSSN (<i>n</i> = 52; 32%) and invasive squamous cell carcinoma in np-OSSN (<i>n</i> = 46; 37%, <i>P</i> = 0.043). Over a mean follow-up period of 9 months (range, 6 months; range, 1-84 months) for np-OSSN and 7 months (median, 3 months; range, 1-51 months) for p-OSSN, the life salvage (98% vs. 99%, <i>P</i> = 0.536), globe salvage (90% versus 92%, <i>P</i> = 0.335), vision salvage (90% vs. 92%, <i>P</i> = 0.416), and local tumor recurrence (5% vs. 3%, <i>P</i> = 0.167) rates were comparable between the groups.</p><p><strong>Conclusion: </strong>Compared to np-OSSN, p-OSSN is commonly associated with co-existent CAM but has similar treatment outcomes.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"16 1","pages":"97-104"},"PeriodicalIF":1.2,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ocular surface squamous neoplasia in Malaysia: A 5-year review. 马来西亚眼表鳞状瘤变:5年回顾。
IF 1.2
Taiwan Journal of Ophthalmology Pub Date : 2025-10-24 eCollection Date: 2026-01-01 DOI: 10.4103/tjo.TJO-D-25-00060
Nor Sharina Binti Yusof, Ahmad Anwaar Muhammad Saifullah, Che Mahiran Che Daud, Rosilah Mohamad, Rohanah Alias
{"title":"Ocular surface squamous neoplasia in Malaysia: A 5-year review.","authors":"Nor Sharina Binti Yusof, Ahmad Anwaar Muhammad Saifullah, Che Mahiran Che Daud, Rosilah Mohamad, Rohanah Alias","doi":"10.4103/tjo.TJO-D-25-00060","DOIUrl":"https://doi.org/10.4103/tjo.TJO-D-25-00060","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of the study was to review the demographic profile, risk factors, clinical presentations, and treatment outcomes in patients with ocular surface squamous neoplasia (OSSN) at government cornea centers in Malaysia.</p><p><strong>Materials and methods: </strong>This is a retrospective cohort study of patients with proven histopathological reports of either corneal/conjunctival intraepithelial neoplasia (CIN) or squamous cell carcinoma (SCC) from January 2016 to December 2021, who were recruited. The patients' demography, histopathology, and treatment outcomes were reviewed.</p><p><strong>Results: </strong>A total of 62 eyes involving 59 patients with proven OSSN were studied. The majority of the cases were male (76.3%), with a mean age of 65.2 ± 11.81 years, and approximately 32.2% worked as farmers. Sun exposure and smoking are the predominant risk factors observed in this study. Histopathological examination revealed that 69.4% were CIN, while 30.6% were SCC. The majority of the cases were treated surgically with adjunctive cryotherapy and topical mitomycin C (MMC) postoperatively. Five cases (3 CIN, 2 SCC) recurred after surgery. Two recurrent cases were treated with topical MMC and resolved completely. Another three cases required surgical excision after chemo reduction with topical MMC. Tumor pigmentation was shown to be a significant risk factor for recurrence (odds ratio 10.7; 95% confidence interval: 1.5-75.8; <i>P</i> = 0.026).</p><p><strong>Conclusion: </strong>CIN is more common than SCC, predominantly affecting the male population in Malaysia with a background history of sun exposure and smoking. MMC is a good adjunct to surgical excision, both for primary and recurrent cases. Tumor pigmentation is a predicting factor for OSSN recurrence.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"16 1","pages":"105-113"},"PeriodicalIF":1.2,"publicationDate":"2025-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147699976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Generative artificial intelligence in ophthalmology research writing: A comprehensive review of applications, detection tools, and ethical considerations. 眼科学研究写作中的生成式人工智能:应用、检测工具和伦理考虑的综合综述。
IF 1.2
Taiwan Journal of Ophthalmology Pub Date : 2025-10-24 eCollection Date: 2026-01-01 DOI: 10.4103/tjo.TJO-D-25-00072
Pin-Jung Cheng, Fang-Yu Hu, Le-Yu Chen, Jen-Yu Liu, Jo-Hsuan Wu, Wei-Li Chen
{"title":"Generative artificial intelligence in ophthalmology research writing: A comprehensive review of applications, detection tools, and ethical considerations.","authors":"Pin-Jung Cheng, Fang-Yu Hu, Le-Yu Chen, Jen-Yu Liu, Jo-Hsuan Wu, Wei-Li Chen","doi":"10.4103/tjo.TJO-D-25-00072","DOIUrl":"https://doi.org/10.4103/tjo.TJO-D-25-00072","url":null,"abstract":"<p><p>The rise of generative artificial intelligence (GenAI) has profoundly influenced medical research and academic writing, particularly in ophthalmology. Despite its growing relevance, there is a noticeable gap in the literature regarding its application in medical writing, including practical uses and associated limitations. This review seeks to fill in this gap by first systematically reviewing the current literature on GenAI in medical paper writing. It identifies and discusses nine key applications and considerations, including idea generation, literature review, institutional review board preparation, data collection, data analysis, image generation, manuscript drafting, writing refinement, and peer review. In the second part, we explore publicly available AI tools that currently assist with medical manuscript writing. We also introduce several generative AI detection tools and discuss their accuracy and reliability. Finally, the review addresses the limitations and ethical challenges associated with the use of GenAI in medical paper writing. While GenAI has streamlined many aspects of medical paper writing, and an increasing number of AI tools have been developed for research, significant model limitations and ethical concerns persist, necessitating careful human oversight and clear guidelines. By providing a comprehensive yet focused overview, this article offers valuable insights into the effective use of GenAI in medical paper writing while acknowledging its limitations and risks. It aims to support researchers in producing high-quality, AI-enhanced publications in the field of ophthalmology.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"16 1","pages":"68-80"},"PeriodicalIF":1.2,"publicationDate":"2025-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147699973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conjunctival microvascular alterations in dry eye disease: A comparative study of Sjögren's and non-Sjögren's subtypes. 干眼病的结膜微血管改变:Sjögren和non-Sjögren亚型的比较研究
IF 1.2
Taiwan Journal of Ophthalmology Pub Date : 2025-10-24 eCollection Date: 2025-10-01 DOI: 10.4103/tjo.TJO-D-25-00108
Jiyoung Emily Lee, Dong-Kyu Kim, Young Chae Yoon, Woong-Joo Whang, Ho Sik Hwang, Hyun-Seung Kim, Dae Yu Kim, Kyung Sun Na
{"title":"Conjunctival microvascular alterations in dry eye disease: A comparative study of Sjögren's and non-Sjögren's subtypes.","authors":"Jiyoung Emily Lee, Dong-Kyu Kim, Young Chae Yoon, Woong-Joo Whang, Ho Sik Hwang, Hyun-Seung Kim, Dae Yu Kim, Kyung Sun Na","doi":"10.4103/tjo.TJO-D-25-00108","DOIUrl":"10.4103/tjo.TJO-D-25-00108","url":null,"abstract":"<p><strong>Purpose: </strong>Conjunctival microvasculature is associated with ocular and systemic diseases. Previous studies have reported increased blood flow velocity (BFV), blood flow rate (BFR), vessel density, and diameter in dry eye disease (DED). This study aimed to compare bulbar conjunctival microvascular morphology and hemodynamics between patients with DED with and without Sjögren's dry eye (SSDE and NSDE) who had comparable symptoms, and to assess their correlations with Meibomian gland dysfunction (MGD) parameters.</p><p><strong>Materials and methods: </strong>In this prospective study, conjunctival imaging for the left eyes of patients with DED was performed using a previously developed optical system incorporating Attention-UNet-based vessel segmentation and a validated two-step motion-correction pipeline. Tear film lipid layer thickness measurement and meibography were performed using the LipiView® II Ocular Surface Inferometer. Microvascular parameters, including BFV, BFR, and diameter, were quantified.</p><p><strong>Results: </strong>The mean microvessel diameter for the SSDE group (12.985 ± 2.478 μm) was significantly higher than that for NSDE (9.431 ± 3.982 μm) (<i>P</i> < 0.050). In the NSDE group, diameter correlated positively with BFR (<i>P</i> < 0.050), and BFR correlated with both upper and lower meiboscores (<i>P</i> < 0.050).</p><p><strong>Conclusion: </strong>These findings reveal distinct conjunctival microvascular signatures in patients with SSDE, and support vessel diameter as a discriminator. The association between hemodynamic changes and MGD parameters in the NSDE group underscores the interplay between MGD and conjunctival microcirculation in NSDE. The differences in microvasculature identified in this study may serve as valuable biomarkers for DED subtype classification and the development of personalized treatment.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"15 4","pages":"589-597"},"PeriodicalIF":1.2,"publicationDate":"2025-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12782496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Posterior capsular rent - Prevention, recognition, and management - A review. 后囊膜撕裂-预防,识别和处理-综述。
IF 1.2
Taiwan Journal of Ophthalmology Pub Date : 2025-09-24 eCollection Date: 2025-10-01 DOI: 10.4103/tjo.TJO-D-25-00059
Mohan Rajan, Arthi Mohankumar, Madhuvanthi Mohan, Sujatha Mohan
{"title":"Posterior capsular rent - Prevention, recognition, and management - A review.","authors":"Mohan Rajan, Arthi Mohankumar, Madhuvanthi Mohan, Sujatha Mohan","doi":"10.4103/tjo.TJO-D-25-00059","DOIUrl":"10.4103/tjo.TJO-D-25-00059","url":null,"abstract":"<p><p>We prefer using posterior capsular rent is a significant intraoperative complication of cataract surgery, often leading to vision-threatening sequelae if not promptly recognized and appropriately managed. PCR can result from various factors, weak zonules, posterior polar cataracts, including improper phacoemulsification techniques, and excessive instrument manipulation. Early recognition is critical, and swept-source optical coherence tomography and intraoperative assessments can enhance early detection. Prevention strategies focus on meticulous surgical planning, careful hydrodissection, judicious use of phaco power, and maintaining anterior chamber (AC) stability. Techniques such as slow-motion phacoemulsification, femtosecond laser-assisted cataract surgery (FLACS), and capsule-stabilizing devices can reduce the risk of PCR in high-risk cases. Once a rupture occurs, prompt and careful management is essential to prevent further complications such as vitreous loss, retained lens fragments, or intraocular lens (IOL) malposition. Anterior vitrectomy using bimanual or coaxial techniques is crucial for clearing vitreous from the AC and preventing traction on the retina. The choice of IOL implantation depends on the extent of PCR, with options including sulcus-fixated, iris-fixated, scleral-fixated, or ACIOLs when capsular support is inadequate. Postoperative management includes monitoring for cystoid macular edema, retinal detachment, and endophthalmitis, which are more common following PCR. This review underscores the importance of surgical vigilance, adherence to best practices, and an individualized approach to optimizing the visual outcomes following this challenging complication.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"15 4","pages":"549-558"},"PeriodicalIF":1.2,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12782498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optical coherence tomography angiography characteristics of microvascular retinal alterations and the relationship with visual impairment in different patterns of retinitis pigmentosa. 不同类型色素性视网膜炎视网膜微血管病变的光学相干断层血管造影特征及其与视力损害的关系。
IF 1.2
Taiwan Journal of Ophthalmology Pub Date : 2025-09-15 eCollection Date: 2025-07-01 DOI: 10.4103/tjo.TJO-D-25-00088
Hsu-Hang Yeh, Chia-Yi Cheng, Ting-Chieh Ko, Chang-Hao Yang, Chung-May Yang, Pei-Lung Chen, Chao-Wen Lin, Teck Boon Tew, Ta-Ching Chen
{"title":"Optical coherence tomography angiography characteristics of microvascular retinal alterations and the relationship with visual impairment in different patterns of retinitis pigmentosa.","authors":"Hsu-Hang Yeh, Chia-Yi Cheng, Ting-Chieh Ko, Chang-Hao Yang, Chung-May Yang, Pei-Lung Chen, Chao-Wen Lin, Teck Boon Tew, Ta-Ching Chen","doi":"10.4103/tjo.TJO-D-25-00088","DOIUrl":"10.4103/tjo.TJO-D-25-00088","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of the study was to evaluate macular microvascular alterations using optical coherence tomography angiography (OCTA) in typical retinitis pigmentosa (RP) patients with and without isolated macular lesions, and to assess their relationship with best-corrected visual acuity (BCVA).</p><p><strong>Materials and methods: </strong>This retrospective study included 77 patients with typical RP from the Taiwan Inherited Retinal Degeneration Project, categorized into two groups: with isolated macular lesions (T+M, <i>n</i> = 44) and without (T, <i>n</i> = 33). Eighteen age-matched healthy individuals served as controls. All participants underwent comprehensive ophthalmic examinations and OCTA imaging. Quantitative parameters-vessel density in superficial and deep retinal plexuses, foveal avascular zone (FAZ) area, and outer retinal flow-were analyzed and correlated with BCVA.</p><p><strong>Results: </strong>Both RP groups showed compromised macular microcirculation compared to controls. FAZ area was significantly larger in the T+M group than in controls (<i>P</i> = 0.01) and showed a trend toward enlargement compared to the T group (<i>P</i> = 0.06). BCVA was significantly worse in the T+M group than in the T group and controls (<i>P</i> = 0.002). In the T+M group, decreased vessel density in the deep plexus, enlarged FAZ, and reduced outer retinal flow were significantly correlated with poorer vision; these correlations were not observed in the T group.</p><p><strong>Conclusion: </strong>Macular microvascular impairment is a common feature in typical RP, but its association with central visual loss is particularly pronounced in those with isolated macular lesions. OCTA parameters may serve as useful biomarkers for clinical monitoring and prognosis in this subgroup.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"15 3","pages":"450-456"},"PeriodicalIF":1.2,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in optical coherence tomography: Celebrating its transformative impact on eye care. 光学相干断层扫描的进展:庆祝其对眼科护理的变革性影响。
IF 1.2
Taiwan Journal of Ophthalmology Pub Date : 2025-09-15 eCollection Date: 2025-07-01 DOI: 10.4103/tjo.TJO-D-25-00118
Yali Jia
{"title":"Advances in optical coherence tomography: Celebrating its transformative impact on eye care.","authors":"Yali Jia","doi":"10.4103/tjo.TJO-D-25-00118","DOIUrl":"10.4103/tjo.TJO-D-25-00118","url":null,"abstract":"","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"15 3","pages":"331-332"},"PeriodicalIF":1.2,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of positive and negative dysphotopsia postcataract surgery - A literature review. 白内障手术后阳性和阴性光线不足的处理-文献综述。
IF 1.2
Taiwan Journal of Ophthalmology Pub Date : 2025-09-10 eCollection Date: 2025-10-01 DOI: 10.4103/tjo.TJO-D-25-00017
Kujani Wanniarachchi, Jodhbir S Mehta
{"title":"Management of positive and negative dysphotopsia postcataract surgery - A literature review.","authors":"Kujani Wanniarachchi, Jodhbir S Mehta","doi":"10.4103/tjo.TJO-D-25-00017","DOIUrl":"10.4103/tjo.TJO-D-25-00017","url":null,"abstract":"<p><p>The objective of this review was to provide a summary of the literature on the etiologies and management of positive (PD) and negative dysphotopsia (ND) which are optical phenomena that occur after routine cataract surgery. A search of PubMed and Google Scholar identified 36 relevant papers. There is a consensus on the etiology of PD, which is attributed to the edge design of the intraocular lens (IOL). A truncated square edge can cause light of an oblique incidence to reflect onto the retinal surface and cause streaks and haloes in the visual field. Other causes of PD include diffractive multifocal IOLs and IOLs with a high index of refraction. The causes of ND are multifactorial; however, the majority of the evidence from experimental and clinical studies supports the \"illumination gap\" of the nasal retina which may arise from the anterior capsule overlying the IOL. Other factors such as pupil size, a high-angle kappa, and increased posterior chamber depth may also play a role. Regarding surgical management, ND has been successfully treated with reverse optic capture, neodymium-doped yttrium aluminum garnet laser capsulectomy, nasal IOL optic truncation, piggyback IOL, and an ND ring. Both PD and ND can be surgically managed by replacing the IOL using in-the-bag exchange or bag-to-sulcus exchange. Technological advancements have presented new avenues for developing antidysphotopsia lenses. Novel approaches utilize anterior capsulotomy fixation using IOL phalanges and a recent diffractive spiral lens that provides smooth full-range vision without dysphotopsia.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"15 4","pages":"572-579"},"PeriodicalIF":1.2,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12782528/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancing optical coherence tomography angiography to the clinic. 推进光学相干断层血管造影到临床。
IF 1.2
Taiwan Journal of Ophthalmology Pub Date : 2025-09-05 eCollection Date: 2025-07-01 DOI: 10.4103/tjo.TJO-D-25-00080
Tristan T Hormel, Yali Jia
{"title":"Advancing optical coherence tomography angiography to the clinic.","authors":"Tristan T Hormel, Yali Jia","doi":"10.4103/tjo.TJO-D-25-00080","DOIUrl":"10.4103/tjo.TJO-D-25-00080","url":null,"abstract":"<p><p>Optical coherence tomography (OCT) angiography (OCTA) is a new clinical technology that advances the capabilities of OCT imaging by adding the ability to readily visualize vascular anatomy down to the capillary scale. With this level of detail, OCTA can be used to identify many important vascular pathologies such as capillary dropout, microaneurysms, or neovascularization. Because it offers high-resolution, high-contrast imaging of these and similar features, OCTA is useful not just for visualization but also for quantification. Quantification is a powerful feature that enables the potential for diagnostics, staging, evaluation of treatment response, and patient monitoring in a more rigorous way than simple observation. In this review, we will examine several OCTA measurements with either demonstrated clinical utility or clinical potential through the lens of three prevalent blinding diseases: diabetic retinopathy, age-related macular degeneration, and glaucoma. We will discuss the merits of these various measurements and care that should be taken in their interpretation and analyze their role in patient management.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"15 3","pages":"333-343"},"PeriodicalIF":1.2,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraoperative optical coherence tomography in ophthalmology: Technologies and applications. 眼科学术中光学相干断层扫描:技术与应用。
IF 1.2
Taiwan Journal of Ophthalmology Pub Date : 2025-09-05 eCollection Date: 2025-07-01 DOI: 10.4103/tjo.TJO-D-25-00076
Yuankai K Tao
{"title":"Intraoperative optical coherence tomography in ophthalmology: Technologies and applications.","authors":"Yuankai K Tao","doi":"10.4103/tjo.TJO-D-25-00076","DOIUrl":"10.4103/tjo.TJO-D-25-00076","url":null,"abstract":"<p><p>Intraoperative optical coherence tomography (iOCT) offers valuable real-time, depth-resolved visualization of ocular anatomy and during ophthalmic surgical maneuvers, which can be used to augment clinical decision-making, help verify surgical endpoints, enhance surgical precision, and facilitate the development of novel surgical techniques. Early iOCT demonstrations used perioperative devices, such as handheld and intraocular probes, which required pauses in surgery and disrupted clinical workflow. The advent of microscope-integrated systems addressed these limitations, allowing for iOCT imaging concurrent with surgical microscopy. iOCT image visualization has similarly progressed from external monitors, which require surgeons to divert their gaze, to heads-up displays integrated into microscope oculars, enabling direct overlays and improved ergonomics. Most recent advances have included increasing imaging speed to enable four-dimensional visualization of surgical dynamics and integration of automated surgical instrument tracking technologies. Clinical translation of iOCT has demonstrated utility across a range of procedures, including glaucoma surgery, corneal transplants, cataract extraction, vitrectomy, membrane peel, retinal detachment and macular hole repair, subretinal injection, and retinal prosthesis placement. As more advanced technologies are integrated into the conventional ophthalmic surgical workflow, iOCT has the potential to improve surgical performance and patient outcomes.</p>","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":"15 3","pages":"378-388"},"PeriodicalIF":1.2,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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