Taiwan Journal of Ophthalmology最新文献_第4页

Evaluating the efficacy of Rho kinase inhibitor eye drops in the management of corneal edema: A single-center retrospective cohort study 评估 Rho 激酶抑制剂滴眼液治疗角膜水肿的疗效：单中心回顾性队列研究

IF 1.1

Taiwan Journal of Ophthalmology Pub Date : 2024-02-20 DOI: 10.4103/tjo.tjo-d-23-00169

Itay Lavy, N. Erdinest, Jamel Corredores, Denise Wajnsztajn, David Smadja

{"title":"Evaluating the efficacy of Rho kinase inhibitor eye drops in the management of corneal edema: A single-center retrospective cohort study","authors":"Itay Lavy, N. Erdinest, Jamel Corredores, Denise Wajnsztajn, David Smadja","doi":"10.4103/tjo.tjo-d-23-00169","DOIUrl":"https://doi.org/10.4103/tjo.tjo-d-23-00169","url":null,"abstract":"\u0000 \u0000 \u0000 This study aimed to evaluate the efficacy of ripasudil in managing various corneal edema conditions.\u0000 \u0000 \u0000 \u0000 This single-center retrospective analysis was conducted at Hadassah Medical Center and involved 16 patients with 17 eyes. Patients were selected based on diagnostic criteria, primarily corneal edema. The conditions were as follows, listed by frequency: postcataract surgery (31.25%), postpenetrating keratoplasty (25%), post-Descemet’s membrane endothelial keratoplasty (18.75%), Fuchs’ endothelial corneal dystrophy (12.5%), status post-Ahmed glaucoma valve (6.25%), and status posttrabeculectomy (6.25%). The treatment regimen involved topical administration of ripasudil hydrochloride hydrate (Glanatec® 0.4%), administered three times a day or tailored to condition severity. Efficacy was assessed using pre- and posttreatment measurements of best-corrected visual acuity (BCVA), central corneal thickness (CCT), and endothelial cell count (ECC), along with slit-lamp and optical coherence tomography examinations.\u0000 \u0000 \u0000 \u0000 The average duration of ripasudil treatment was approximately 4.9 ± 2.2 months. Significant improvements were observed in BCVA, changing from a pretreatment value of 1.106 ± 0.817 logMAR to a posttreatment value of 0.56 ± 0.57 logMAR (P = 0.0308). CCT also showed a significant reduction, from 619.50 ± 56.36 μm pretreatment to 572.5 ± 75.48 μm posttreatment (P = 0.0479). ECC showed a marginal but not statistically significant increase, from 849.00 ± 570.72 cells/mm² pretreatment to 874.75 ± 625.59 cells/mm² posttreatment (P = 0.9010).\u0000 \u0000 \u0000 \u0000 The study provides robust evidence supporting the use of ripasudil in managing corneal edema. Significant improvements in key ocular metrics such as BCVA and CCT were observed, enhancing the overall quality of life for patients suffering from various forms of corneal edema.\u0000","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140446939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vitrectomy for diabetic retinopathy: A review of indications, techniques, outcomes, and complications 糖尿病视网膜病变的玻璃体切除术：适应症、技术、结果和并发症综述

IF 1.1

Taiwan Journal of Ophthalmology Pub Date : 2024-01-31 DOI: 10.4103/tjo.tjo-d-23-00108

Nimesh C. Patel, Yi-Ting Hsieh, Chung M Yang, M. Berrocal, F. Dhawahir-Scala, Paisan Ruamviboonsuk, RajeevReddy Pappuru, V. Dave

引用次数: 0

Risk factors for corneal endothelial cell loss after phacoemulsification 超声乳化术后角膜内皮细胞脱落的风险因素

IF 1.1

Taiwan Journal of Ophthalmology Pub Date : 2024-01-30 DOI: 10.4103/tjo.tjo-d-23-00146

N. S. Lee, Keith Ong

{"title":"Risk factors for corneal endothelial cell loss after phacoemulsification","authors":"N. S. Lee, Keith Ong","doi":"10.4103/tjo.tjo-d-23-00146","DOIUrl":"https://doi.org/10.4103/tjo.tjo-d-23-00146","url":null,"abstract":"\u0000 \u0000 \u0000 The purpose of this study was to evaluate the changes in corneal endothelial cell density (CECD) occurring after cataract phacoemulsification surgery and identify factors associated with cell loss.\u0000 \u0000 \u0000 \u0000 This was a retrospective study involving patients who underwent cataract phacoemulsification surgery between January 1, 2018, and December 31, 2018, at two private hospitals. Demographic data and biometric parameters were obtained preoperatively. Ultrasound metrics were recorded for each operation, including total on time (TOT), total equivalent power in position 3, and cumulative dissipated energy (CDE). Using corneal specular microscopy, CECD was measured preoperatively and postoperatively at 12, 24, and 36 months. Factors associated with decreased CECD were identified.\u0000 \u0000 \u0000 \u0000 This study included 223 eyes of 133 patients. The mean CECD was 2530.03 ± 285.42 cells/mm2 preoperatively and significantly decreased to 2364.22 ± 386.98 cells/mm2 at 12 months (P < 0.001), 2292.32 ± 319.72 cells/mm2 at 24 months (P < 0.001), and 2242.85 ± 363.65 cells/mm2 at 36 months (P < 0.001). The amount of cell loss was associated with age, gender, preoperative CECD, preoperative anterior chamber depth, lens thickness, TOT, and CDE. Using multivariate analysis, age, preoperative CECD, and TOT were identified as independent predictors for CECD loss 12 months after surgery.\u0000 \u0000 \u0000 \u0000 The greatest decrease in CECD occurred during the first year after cataract surgery, and the amount of cell loss was influenced by both baseline patient characteristics and ultrasound metrics. Longer-term prospective studies in a larger cohort may yield more information.\u0000","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140480473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of ARMS2/HTRA1 risk alleles in the pathogenesis of neovascular age-related macular degeneration ARMS2/HTRA1 风险等位基因在新生血管性老年黄斑变性发病机制中的作用

IF 1.1

Taiwan Journal of Ophthalmology Pub Date : 2024-01-29 DOI: 10.4103/tjo.tjo-d-23-00152

Yang Pan, Takeshi Iwata

引用次数: 0

Ectopia Lentis: Clinical profiles in a large cohort of children from a Tertiary Eye Care network in India 眼睑外翻：来自印度三级眼科医疗网络的一大批儿童的临床特征

IF 1.1

Taiwan Journal of Ophthalmology Pub Date : 2024-01-19 DOI: 10.4103/tjo.tjo-d-23-00150

M. Bhate, A. Das, R. Kekunnaya, V. Sachdeva, Muralidhar Ramappa, V. Warkad, Debasmita Majhi

{"title":"Ectopia Lentis: Clinical profiles in a large cohort of children from a Tertiary Eye Care network in India","authors":"M. Bhate, A. Das, R. Kekunnaya, V. Sachdeva, Muralidhar Ramappa, V. Warkad, Debasmita Majhi","doi":"10.4103/tjo.tjo-d-23-00150","DOIUrl":"https://doi.org/10.4103/tjo.tjo-d-23-00150","url":null,"abstract":"\u0000 \u0000 \u0000 To study the clinical presentations, visual, and refractive profiles of children with congenital ectopia lentis in a large cohort of patients from a tertiary eye care network in India.\u0000 \u0000 \u0000 \u0000 A retrospective review of electronic medical records from December 2012 to December 2020 was conducted. Two hundred and ninety-seven consecutive children ≤18 years of age at presentation were identified and analyzed for demographic details, patient distribution, lens subluxation, visual, and refractive profiles before and after the interventions.\u0000 \u0000 \u0000 \u0000 Five hundred and ninety-four eyes of 297 (male 56%; n = 166) patients were analyzed. The mean age at presentation was 8.74 ± 3.89. Best-corrected visual acuity (BCVA) at presentation ranged from 0.3 logMAR to 3.5 logMAR; (Snellen: 6/9 – close to face [CF]) (mean 0.89 ± 0.68). High myopia (n = 201; 33.83%) and mild astigmatism (n = 340; 57.23%) were more frequent. Temporal (n = 108; 18.18%) subluxation was most common followed by superior. Lensectomy with limited vitrectomy was performed in 243 eyes of 127 patients (40.90%). Median preoperative BCVA was 1.0 (range: 0.3–3.5 logMAR; 20/40 - CF). Median postoperative BCVA was 0.5 logMAR (6/18) in the pseudophakic group and 0.6 logMAR (6/24) in the aphakic group. Spherical equivalent in myopic children reduced from −12.06 ± 6.84D to −1.57D (−0.25D to − 5.5D) in the pseudophakic group and +9.3D (+5.5D to 15.5D) in the aphakic group.\u0000 \u0000 \u0000 \u0000 This study is a large cohort of children presenting with ectopia lentis. Following intervention, an improvement in the median BCVA and refractive correction was noted in the entire cohort.\u0000","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139524930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Full-tendon inferior nasal transposition of the lateral rectus muscle for partial third nerve palsy 外侧直肌全肌腱下鼻翼转位术治疗部分第三神经麻痹

IF 1.1

Taiwan Journal of Ophthalmology Pub Date : 2024-01-11 DOI: 10.4103/tjo.tjo-d-23-00144

Dolgormaa Budragchaa, Chun-Hsiu Liu

引用次数: 0

Acute acquired comitant esotropia: Current understanding of its etiological classification and treatment strategies 急性获得性合并内斜视：目前对其病因分类和治疗策略的理解

IF 1.1

Taiwan Journal of Ophthalmology Pub Date : 2024-01-11 DOI: 10.4103/tjo.tjo-d-23-00084

Noriko Nishikawa, Miho Sato

引用次数: 0

Resurgence of orbital mucormycosis during COVID-19 pandemic: Study from a tertiary care center in Eastern India COVID-19大流行期间眼眶粘液瘤病复发：印度东部一家三级医疗中心的研究

IF 1.1

Taiwan Journal of Ophthalmology Pub Date : 2024-01-09 DOI: 10.4103/tjo.tjo-d-23-00110

Soumen Chakraborty, Satish Reddy Satty, Badal Kumar Sahu, Soumya Ray

{"title":"Resurgence of orbital mucormycosis during COVID-19 pandemic: Study from a tertiary care center in Eastern India","authors":"Soumen Chakraborty, Satish Reddy Satty, Badal Kumar Sahu, Soumya Ray","doi":"10.4103/tjo.tjo-d-23-00110","DOIUrl":"https://doi.org/10.4103/tjo.tjo-d-23-00110","url":null,"abstract":"\u0000 \u0000 \u0000 A sudden surge of Mucormycosis cases during the second wave of Covid 19 was observed in certain parts of India. The reasons for this upsurge remain unknown. However its impact on the overall healthcare system was quite overwhelming. In this context this study was decided to estimate and assess the spectrum of orbital involvement in patients with Mucormycosis, to find its association with coexisting disease entities if any, and at the same time evaluate the therapeutic response to established treatment regimens.\u0000 \u0000 \u0000 \u0000 This descriptive longitudinal study was conducted over a period of six months. Patients presenting with symptoms of Mucormycosis were jointly evaluated by a multi speciality team. After confirmation of diagnosis, patients were treated with intravenous Amphotericin B, surgical debridement of affected sinuses and orbital exenteration when indicated. They were followed up for three months after discharge.\u0000 \u0000 \u0000 \u0000 Forty-three patients were enrolled in this study. Thirty-seven (86.04%) were COVID positive. All of them had history of steroid exposure during COVID treatment. Ninety five percent of study participants had diabetes mellitus. Twenty-seven (62.79%) patients had orbital involvement. Most common clinical presentation was peri-orbital or facial pain and edema. Besides medical treatment, thirty-nine patients (90.69%) required sinus debridement and nine patients (20.9%) required orbital exenteration. Thirteen patients (30.23%) expired during the follow up period. With treatment disease regressed in twenty patients (46.51%).\u0000 \u0000 \u0000 \u0000 Diabetes and use of steroids to prevent anticipated cytokine storm may be the inciting factors for Orbital Mucormycosis in COVID patients. Early diagnosis, treatment and control of risk factors are keys for recovery and survival..\u0000","PeriodicalId":44978,"journal":{"name":"Taiwan Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139443015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cancer-associated retinopathy as an initial presentation of gynecologic small-cell carcinoma 癌症相关性视网膜病变是妇科小细胞癌的最初表现形式

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Taiwan Journal of Ophthalmology Pub Date : 2024-01-09 DOI: 10.4103/tjo.tjo-d-23-00100

Hwa-Shin Fang, Chang-Sue Yang, Cheng-Kuo Cheng, Yuangwei Wang

引用次数: 0

An update on the ocular manifestations of dengue 登革热眼部表现的最新进展

IF 1.1

Taiwan Journal of Ophthalmology Pub Date : 2024-01-09 DOI: 10.4103/tjo.tjo-d-23-00106

Christina Wang, Arturo Castillo, Federico Cortes-Bejarano, Eduardo Lopez, Eduardo Cunha de Souza, Lihteh Wu

引用次数: 0