Ultrasound International Open最新文献

{"title":"Tumor Size Discrepancies with Different Measurement Methods in Papillary Thyroid M​​​​​icrocarcinoma.","authors":"Risa Kanematsu, Mitsuyoshi Hirokawa, Miyoko Higuchi, Ayana Suzuki, Makoto Kawakami, Rie Goryo, Makoto Fujishima, Akira Miyauchi, Takashi Akamizu","doi":"10.1055/a-2923-0168","DOIUrl":"10.1055/a-2923-0168","url":null,"abstract":"<p><p><b>Purpose</b> Measurement of tumor size is critical for thyroid tumor management; however, optimal measurement methods and evaluation criteria remain unclear. This study aimed to quantitatively compare the papillary thyroid microcarcinoma tumor size measured by ultrasound, gross examination, and histological assessment and to determine how discrepancies between these different measurements may influence clinical decision making, such as indications for fine-needle aspiration, eligibility for active surveillance, and surgical management. <b>Materials and methods</b> This study included 412 papillary thyroid carcinoma cases with tumors of < 15 mm on preoperative ultrasound examination. <b>Results</b> The reduction rates of gross and histological sizes compared to ultrasound sizes were 93.5% and 86.9%, respectively. Significant differences were observed between all combinations of ultrasound, gross, and histological sizes ( <i>p<</i> 0.001). Papillary thyroid microcarcinoma accounted for 42.0%, 55.6%, and 65.1% of cases, respectively. In 23 cases, the difference between the ultrasound and gross or histological sizes was >5 mm. This was because they were not cut at the maximal plane, were located in the isthmus or inferior pole, were associated with chronic thyroiditis, and were lobulated. <b>Conclusions</b> We demonstrated that the size of papillary thyroid carcinoma depends on the measurement method used. Gross and histological tumor sizes tended to be smaller than ultrasonographic sizes. Clinicians should be aware that tumors slightly exceeding 10 mm on ultrasound may ultimately be classified as papillary thyroid microcarcinoma postoperatively. Tumor location, shape, and coexisting thyroiditis can all contribute to measurement errors in ultrasound.</p>","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"12 ","pages":"a29230168"},"PeriodicalIF":3.1,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13551462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148913736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Didactic Ultrasound Manual for identifying lumbar Plexus Peripheral Nerves in the lower limb: Lower Abdominal Wall, Groin and Thigh.","authors":"Juan Antonio Valera-Calero","doi":"10.1055/a-2920-0129","DOIUrl":"10.1055/a-2920-0129","url":null,"abstract":"<p><strong>Purpose: </strong>The lumbar plexus, formed by the anterior rami of T12/L1 to L4/L5, provides the main neural supply to the lower abdominal wall, groin, and anterior-medial thigh. Its principal peripheral branches (the iliohypogastric, ilioinguinal, genitofemoral, lateral femoral cutaneous, femoral, and obturator nerves) are clinically relevant targets for invasive diagnostic and therapeutic procedures, including nerve blocks and neuromodulatory techniques. This manual aims to describe how to visualize these six main lumbar plexus branches using ultrasound guidance.</p><p><strong>Materials and methods: </strong>For each nerve, this guide summarizes its typical anatomical course, key clinical considerations related to neuropathy or iatrogenic injury, the most relevant anatomical landmarks, recommended transducer positioning, and characteristic sonographic appearance. The text is complemented by illustrations of probe placement, schematic depictions of nerve pathways, and representative ultrasound images.</p><p><strong>Results: </strong>This manual provides a structured ultrasound-based approach for identifying the main lumbar plexus branches in the lower abdominal wall, groin, and thigh. It details the anatomical and sonographic features that facilitate nerve recognition and supports precise probe positioning and needle guidance when these nerves are targeted in clinical practice.</p><p><strong>Conclusions: </strong>Ultrasound guidance is encouraged when performing procedures involving lumbar plexus branches, as it may improve procedural accuracy and patient safety by enabling precise needle placement while reducing the risk of injury to adjacent non-target structures. This manual offers a practical anatomical and sonographic reference for clinicians performing ultrasound-guided interventions in this region.</p>","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"12 ","pages":"a29200129"},"PeriodicalIF":3.1,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13463367/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148726206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers to the Broader Use of Contrast-Enhanced Ultrasound in Saudi Healthcare and Medical Research.","authors":"Shatha Jamal Almushayt","doi":"10.1055/a-2899-0967","DOIUrl":"10.1055/a-2899-0967","url":null,"abstract":"<p><p><b>Purpose</b> The aim of this study was to describe the current use of contrast-enhanced ultrasound in Saudi Arabia, identify barriers to its adoption, and propose strategies to support wider clinical utilization. <b>Materials and methods</b> A cross-sectional online survey was distributed to more than 5,000 healthcare practitioners between July and October 2025. Ninety-two eligible responses were included and analyzed using descriptive statistics. An additional qualitative input was obtained from contrast agent suppliers to contextualize survey findings. <b>Results</b> Clinical use of contrast-enhanced ultrasound was limited, with 79% of respondents reporting no current application. Among active users, most performed one to five contrast-enhanced ultrasound examinations per month. Formal contrast-enhanced ultrasound training was uncommon, despite strong interest in education. Major barriers included lack of training opportunities, low clinical awareness, regulatory constraints, and limited availability of contrast-enhanced ultrasound-capable equipment. Supplier feedback corroborated these barriers and highlighted the need for structured education and research collaboration. <b>Conclusions</b> Contrast-enhanced ultrasound is markedly underutilized in Saudi Arabia, primarily due to educational, regulatory, and resource-related barriers. These findings support national initiatives to expand access, enhance training programs, and promote integration of contrast-enhanced ultrasound into routine clinical and research practice.</p>","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"12 ","pages":"a28990967"},"PeriodicalIF":3.1,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13643735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149138566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An End-to-end Interactive Software for Pediatric Pneumonia Severity Assessment from Lung Ultrasound Images.","authors":"Shuo Li, Xue Yang, Yue Jiang, Lingling Zhang, Qili Zhang, Zufei Li","doi":"10.1055/a-2879-4395","DOIUrl":"10.1055/a-2879-4395","url":null,"abstract":"<p><strong>Purpose: </strong>To develop and validate an end-to-end interactive software that integrates lung ultrasound radiomics and machine learning for the objective assessment of pediatric pneumonia severity at the point of care.</p><p><strong>Materials and methods: </strong>This retrospective study included a dataset of lung ultrasound images from 293 pediatric patients (157 with mild pneumonia and 136 with severe pneumonia). A total of 104 radiomics features were extracted from clinician-delineated regions of interest. Feature selection was performed using Least Absolute Shrinkage and Selection Operator regression, and 10 machine learning algorithms were constructed and evaluated. The optimal model was interpreted using SHapley Additive exPlanations. The finalized classifier was integrated into an interactive software platform that guides users from image upload to severity prediction.</p><p><strong>Results: </strong>The Light Gradient Boosting Machine classifier, which forms the core of the software, demonstrated superior performance on the independent test set, achieving an accuracy of 89.8%, a sensitivity of 91.7%, a specificity of 88.6%, and an area under the curve of 90.1%. SHapley Additive exPlanation analysis identified and ranked the contribution of key predictive features, with morphological characteristics being the most influential.</p><p><strong>Conclusions: </strong>We present an end-to-end interactive software that successfully leverages lung ultrasound radiomics and machine learning to provide an objective, accurate, and rapid assessment of pediatric pneumonia severity. This tool has significant potential to standardize diagnosis and support clinical decision-making in real-world settings.</p>","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"12 ","pages":"a28794395"},"PeriodicalIF":3.1,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13289568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148319677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perusal of Newly Developed Diffuse Sclerosing Papillary Thyroid Carcinoma During Follow-up of Benign Nodules in Thyroidology.","authors":"Ilker Sengul, Demet Sengul","doi":"10.1055/a-2858-9794","DOIUrl":"https://doi.org/10.1055/a-2858-9794","url":null,"abstract":"","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"12 ","pages":"a28589794"},"PeriodicalIF":3.1,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13289571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148319714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Diagnostic Utility of Ultrasound in Myxofibrosarcoma: Insights From a Multimodal Imaging Case Study.","authors":"Neil Limaye, Hannah Masraf, Henry Conchie, Adrian Lim","doi":"10.1055/a-2826-3276","DOIUrl":"10.1055/a-2826-3276","url":null,"abstract":"","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"12 ","pages":"a28263276"},"PeriodicalIF":3.1,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13093116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decoding Occult Spinal Dysraphism: A Pictorial Essay of Split Cord Malformation With Prenatal and Postmortem Imaging Correlation.","authors":"Kakoly Borthakur, Nishigandha Mali, Ishika Borthakur","doi":"10.1055/a-2844-6196","DOIUrl":"10.1055/a-2844-6196","url":null,"abstract":"","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"12 ","pages":"a28446196"},"PeriodicalIF":3.1,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13077585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147692953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contrast-enhanced Perfusion Measurements in Patients with Active Crohn's Disease Using Sonazoid.","authors":"Kim Nylund, Fredrik Sævik, Odd Helge Gilja","doi":"10.1055/a-2830-9879","DOIUrl":"10.1055/a-2830-9879","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to assess the feasibility of dynamic contrast-enhanced ultrasound with Sonazoid, its correlation with disease activity, its ability to differentiate between remission/mild activity and moderate/severe activity, and if a region of interest including the mucosa and submucosa was different compared to one encompassing the entire wall.</p><p><strong>Materials and methods: </strong>We prospectively studied 48 patients with Crohn's disease who underwent colonoscopy and dynamic contrast-enhanced ultrasound with Sonazoid from 2015 to 2019. We compared the local simple endoscopic score for Crohn's disease in the most affected area with parameters from Vuebox, including peak enhancement, wash-in and wash-out area under the curves, wash-in and wash-out rates, and wash-in perfusion index. Region of interest-1 (ROI-1) included all wall layers, and region of interest-2 (ROI-2) included the mucosa and submucosa. Linear data and normalised data were used. Technical failure or a quality of fit value of<80% was considered a failed examination.</p><p><strong>Results: </strong>The feasibility of the dynamic contrast-enhanced ultrasound examination was 73%. No significant findings were noted in the linear data ( <i>p</i> >0.05). In the normalised data in both ROI-1 and ROI-2, the local simple endoscopic score for Crohn's disease correlated significantly with peak enhancement ( <i>r</i> =0.38 and <i>r</i> =0.35), wash-in rate ( <i>r</i> =0.34 and <i>r</i> =0.34), and wash-in perfusion index ( <i>r</i> =0.40 and <i>r</i> =0.37) and with wash-in area under the curve ( <i>r</i> =0.36) in ROI-2. In patients with moderate/severe disease peak enhancement, wash-in area under the curve, wash-out area under the curve, wash-in rate, and wash-in perfusion index were significantly higher in both region of interests ( <i>p</i> <0.05). All parameters were significantly different in ROI-1 and ROI-2 ( <i>p</i> <0.05).</p><p><strong>Conclusions: </strong>Dynamic contrast-enhanced ultrasound parameters can differentiate between remission/mild and moderate/severe activity in Crohn's disease, but the method has relatively low feasibility.</p>","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"12 ","pages":"a28309879"},"PeriodicalIF":3.1,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062680/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147677441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Newly developed diffuse sclerosing papillary thyroid carcinoma during follow-up of benign thyroid nodules: a case report of two cases with ultrasound findings.","authors":"Rie Goryo, Mitsuyoshi Hirokawa, Ayana Suzuki, Minoru Kihara, Sayo Nishikawa, Maki Oshita, Hiroyuki Yamaoka, Eijun Nishihara, Makoto Fujishima, Akira Miyauchi, Takashi Akamizu","doi":"10.1055/a-2741-4863","DOIUrl":"https://doi.org/10.1055/a-2741-4863","url":null,"abstract":"","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"11 ","pages":"a27414863"},"PeriodicalIF":3.1,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13299723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148346513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"B-mode ultrasound and dynamic contrast-enhanced ultrasound (DCE-US) of the bowel wall in patients with gastrointestinal food allergy in comparison to Crohn's disease and healthy controls.","authors":"Dane Wildner, Martin Raithel, Maximilian J Waldner, Alexander F Hagel, Markus F Neurath, Lukas Pfeifer","doi":"10.1055/a-2735-9906","DOIUrl":"10.1055/a-2735-9906","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to assess bowel wall thickness using B-mode ultrasound (US) and perfusion measurement by DCE-US in patients with a food allergy (FA) compared to healthy controls (HCs) and patients with active Crohn's disease (CD).</p><p><strong>Materials and methods: </strong>Bowel wall thickness and perfusion were assessed in FA patients as well as in HCs on a potato rice diet (PRD) and after a provocation diet (PD). Additionally, patients with active CD were examined for further comparison.</p><p><strong>Results: </strong>A total of 48 individuals (20 with FAs, 20 with CD, and 8 HCs) were included. There was no significant difference between the HCs and patients with FAs regarding the thickness of the terminal ileum (1.8mm vs. 2.2mm; p=0.46) and the sigmoid colon (2.1mm vs. 2.1mm; p=1) on a PRD. After a PD, the median value was significantly lower in the terminal ileum for HCs compared to patients with FAs (1.6 mm vs. 2.3 mm; p=0.03). In CD patients, the thickness of the terminal ileum was far more pronounced (median thickness 6 mm) compared to HCs and patients with FAs (p<0.001). There was no statistically significant difference for all tested DCE-US parameters in the terminal ileum between the HCs and patients with FAs on either PRD or PD. However, DCE-US perfusion parameters (PE, WiAUC, WiR, WiPi, and WoR) were significantly higher in patients with CD compared to HCs and patients with FAs on a PD.</p><p><strong>Conclusion: </strong>Assessment of wall thickening of the terminal ileum using US and perfusion measurements via DCE-US appears to be insufficient for distinguishing between HCs and patients with FAs. However, US and DCE-US could be helpful in differentiating patients with CD from those with FAs.</p>","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"11 ","pages":"a27359906"},"PeriodicalIF":3.1,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13299687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148346306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}