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Molecular Imaging and Radionuclide Therapy最新文献

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Unveiling the Diagnostic Mystery: 18F-FDG PET and Bone Scan Negative in Bone Metastases of Lobular Breast Cancer: A Case Report. 揭示诊断之谜：18F-FDG PET和骨扫描阴性小叶乳腺癌骨转移1例报告。
IF 1.1
Molecular Imaging and Radionuclide Therapy Pub Date : 2025-08-01 DOI: 10.4274/mirt.galenos.2025.75875
Sharjeel Usmani, Khulood Al Riyami, Anjali Jain, Asiya Al Busaidi, Paul Dumasig, Vipin V Jayakrishnan, Subhash Kheruka, Najeeb Ahmed
{"title":"Unveiling the Diagnostic Mystery: <sup>18</sup>F-FDG PET and Bone Scan Negative in Bone Metastases of Lobular Breast Cancer: A Case Report.","authors":"Sharjeel Usmani, Khulood Al Riyami, Anjali Jain, Asiya Al Busaidi, Paul Dumasig, Vipin V Jayakrishnan, Subhash Kheruka, Najeeb Ahmed","doi":"10.4274/mirt.galenos.2025.75875","DOIUrl":"https://doi.org/10.4274/mirt.galenos.2025.75875","url":null,"abstract":"<p><p>Identifying osseous metastases by imaging is essential and may be challenging in patients with lobular breast cancer. We present a case of a 66-year-old woman with lobular breast cancer who underwent <sup>18</sup>F- fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) for staging purposes. <sup>18</sup>F-FDG PET/CT reveals minimal FDG uptake in the primary tumor cells. Prominent sclerotic lesions with low FDG avidity are seen in the spinal and pelvic bones. The subsequent Tc-99m methylene diphosphonate bone scan is unremarkable. The magnetic resonance multiple imaging (MRI) reveals bone metastases. MRI may be beneficial in invasive lobular carcinoma. MRI facilitates improved metastatic evaluation, especially in bone-only and bone-predominant metastatic malignancies, when assessment with <sup>18</sup>F-FDG PET/CT may be difficult and constrained.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144761740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Bone Scintigraphy in Detection of Disseminated Coccidioides Fungemia. 骨显像在弥散性球虫真菌病检测中的作用。
IF 1.1
Molecular Imaging and Radionuclide Therapy Pub Date : 2025-08-01 DOI: 10.4274/mirt.galenos.2025.65471
Turgut Bora Cengiz, Caroline Diane Wilson
{"title":"The Role of Bone Scintigraphy in Detection of Disseminated Coccidioides Fungemia.","authors":"Turgut Bora Cengiz, Caroline Diane Wilson","doi":"10.4274/mirt.galenos.2025.65471","DOIUrl":"https://doi.org/10.4274/mirt.galenos.2025.65471","url":null,"abstract":"<p><p>Although extrapulmonary Coccidioides infection is rare, it has been shown to disseminate to the skin and musculoskeletal system, with a strong affinity for bone. We present a case of disseminated Coccidioides infection with bone scintigraphy indicating diffuse fungemia despite equivocal serum assay, leading to appropriate antifungal therapy and a full recovery.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144761739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extensive Malignant Thrombus Revealed by 18F-FDG PET/CT in Patient with Papillary Thyroid Cancer. 18F-FDG PET/CT显示甲状腺乳头状癌患者广泛恶性血栓。
IF 1.1
Molecular Imaging and Radionuclide Therapy Pub Date : 2025-08-01 DOI: 10.4274/mirt.galenos.2025.15986
Merve Nida Calderon Tobar, Lütfü Perktaş, Hasan Önner, Gonca Kara Gedik
{"title":"Extensive Malignant Thrombus Revealed by <sup>18</sup>F-FDG PET/CT in Patient with Papillary Thyroid Cancer.","authors":"Merve Nida Calderon Tobar, Lütfü Perktaş, Hasan Önner, Gonca Kara Gedik","doi":"10.4274/mirt.galenos.2025.15986","DOIUrl":"https://doi.org/10.4274/mirt.galenos.2025.15986","url":null,"abstract":"<p><p>A 59-year-old man admitted to the hospital complained of left arm and neck pain. Magnetic resonance imaging was performed for possible cervical discopathy. It revealed that in the C7 vertebral body, lesions with surrounding bone marrow edema were observed, which were compatible with metastasis that caused cervical stenosis. Cervical stenosis surgery was performed, and the lesion was pathologically diagnosed as a metastasis of thyroid carcinoma. <sup>18</sup>F-fluorodeoxyglucose positron emission tomography/computed tomography (<sup>18</sup>F-FDG PET/CT) scan was ordered for further evaluation. The PET/CT images showed an increased <sup>18</sup>F-FDG uptake from the left internal jugular vein to the right atrium. It was considered a malignant thrombus.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144761735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Interesting Case of Fornix Rupture Discovered Accidentally on Bone Scintigraphy. 骨显像意外发现穹窿破裂一例。
IF 1.1
Molecular Imaging and Radionuclide Therapy Pub Date : 2025-08-01 DOI: 10.4274/mirt.galenos.2025.43402
Salah Nabih Oueriagli, Ayoub Dribla, Omar Ait Sahel, Yassir Benameur, Abderrahim Doudouh
{"title":"An Interesting Case of Fornix Rupture Discovered Accidentally on Bone Scintigraphy.","authors":"Salah Nabih Oueriagli, Ayoub Dribla, Omar Ait Sahel, Yassir Benameur, Abderrahim Doudouh","doi":"10.4274/mirt.galenos.2025.43402","DOIUrl":"https://doi.org/10.4274/mirt.galenos.2025.43402","url":null,"abstract":"<p><p>A 62-year-old male patient, with bladder carcinoma, was referred to our institution for Technetium-99m methylene diphosphonate bone scintigraphy to assess for bone metastasis. While the bone scan showed no abnormal uptake, extraosseous uptake was detected in the left perirenal and pelvic regions on the whole body scan. Computed tomography showed fornix rupture and demonstrated tracer pooling in the perirenal collection. Our diagnosis was very consistent, and oriented the therapeutic attitude towards a percutaneous drainage for the perinephric urinary leak.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144761732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare Acute Polyarticular Gout Disease Detected with 18F-FDG PET/CT. 18F-FDG PET/CT检测罕见急性多关节痛风病。
IF 1.1
Molecular Imaging and Radionuclide Therapy Pub Date : 2025-08-01 DOI: 10.4274/mirt.galenos.2025.03764
Zehranur Tosunoğlu, Ayşe Nur Toksöz Yıldırım, Esra Arslan, Göksel Alçın, Elife Akgün
{"title":"Rare Acute Polyarticular Gout Disease Detected with <sup>18</sup>F-FDG PET/CT.","authors":"Zehranur Tosunoğlu, Ayşe Nur Toksöz Yıldırım, Esra Arslan, Göksel Alçın, Elife Akgün","doi":"10.4274/mirt.galenos.2025.03764","DOIUrl":"https://doi.org/10.4274/mirt.galenos.2025.03764","url":null,"abstract":"<p><p>Gout is an inflammatory arthropathy that develops due to the accumulation of monosodium urate crystals in the joints in adults. In approximately half of the cases, it presents as monoarthritis with an acute attack involving the first metatarsophalangeal joint. The first attack is rarely polyarticular. Herein, we present a male patient who presented with swelling and acute pain in the 5<sup>th</sup> toe but <sup>18</sup>F-fluorodeoxyglucose positron emission tomography/computed tomography showed symmetric polyarticular involvement which was mimicking arthritis.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144761738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comprehensive Diagnostic Assessment of Thyroid Nodules Utilizing Scintigraphy and Telomere Lengths (T/S ratios). 利用闪烁成像和端粒长度（T/S比）对甲状腺结节的综合诊断评估。
IF 0.9
Molecular Imaging and Radionuclide Therapy Pub Date : 2025-06-03 DOI: 10.4274/mirt.galenos.2025.85429
Fulya Koç Öztürk, Semra Usta Özdemir, Ersen Karakılıç, Fatma Sılan
{"title":"A Comprehensive Diagnostic Assessment of Thyroid Nodules Utilizing Scintigraphy and Telomere Lengths (T/S ratios).","authors":"Fulya Koç Öztürk, Semra Usta Özdemir, Ersen Karakılıç, Fatma Sılan","doi":"10.4274/mirt.galenos.2025.85429","DOIUrl":"10.4274/mirt.galenos.2025.85429","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to evaluate the effectiveness and role of telomere length measurements in leukocytes, plasma free cell DNA (cfDNA), and biopsy cells, along with technetium-99m (Tc-99m) methoxyisobutylisonitrile (MIBI) scintigraphy, as non-invasive methods for diagnosing malignant thyroid lesions.</p><p><strong>Methods: </strong>Data from 128 patients, who underwent ultrasound, Tc-99m MIBI scintigraphy, and fine-needle biopsy with a preliminary diagnosis of malignant thyroid nodules, were analyzed. In 98 patients, telomere lengths in leukocytes (from blood), cfDNA (from plasma), and biopsy cells were measured using the quantitative polymerase chain reaction method, and the relative telomere/single copy gene (T/S) ratio was calculated. Based on cytological examination results, patients were categorized into three groups: malignant, benign, and suspicious. Group differences were analyzed using the Kruskal-Wallis and Chi-square tests, and correlations between variables were examined with Spearman correlation analysis.</p><p><strong>Results: </strong>The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of Tc-99m MIBI scintigraphy for diagnosing malignant thyroid nodules were 64.70%, 79.16%, 29.72%, 83.51%, and 67.96%, respectively. While these results align with the literature, the positive predictive value was notably lower. No significant differences were observed in telomere lengths (T/S ratios) in leukocytes, plasma, or tissue between the groups.</p><p><strong>Conclusion: </strong>Tc-99m MIBI scintigraphy demonstrates reasonable diagnostic accuracy for identifying malignancy in thyroid nodules. Contrary to limited reports, telomere length measurements may not be a reliable method for predicting thyroid malignancy. Larger studies are needed to further explore these findings.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"34 2","pages":"97-106"},"PeriodicalIF":0.9,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disseminated candidiasis on FDG-PET/CT. FDG-PET/CT显示播散性念珠菌病。
IF 0.9
Molecular Imaging and Radionuclide Therapy Pub Date : 2025-06-03 DOI: 10.4274/mirt.galenos.2025.93276
Yassir Benameur, Adnane Hammani, Kamal Doghmi, Abderrahim Doudouh
{"title":"Disseminated candidiasis on FDG-PET/CT.","authors":"Yassir Benameur, Adnane Hammani, Kamal Doghmi, Abderrahim Doudouh","doi":"10.4274/mirt.galenos.2025.93276","DOIUrl":"10.4274/mirt.galenos.2025.93276","url":null,"abstract":"<p><p>Disseminated candidiasis presents a significant diagnostic and therapeutic challenge in immunocompromised patients, particularly those with hematological malignancies like leukemia. <sup>18</sup>F-fluorodeoxyglucose positron emission tomography/computed tomography (<sup>18</sup>F-FDG-PET/CT) is a crucial imaging modality in oncology and infection, outperforming conventional imaging in diagnosing and managing fungal infections, especially in cases of fever of unknown origin. We present a compelling case of a young leukemia patient with persistent fever, demonstrating FDG-avid lesions in various organs, including the liver, spleen, and left kidney, indicative of disseminated candidiasis.This highlights the critical role of <sup>18</sup>F-FDG-PET/CT in situations where invasive procedures like liver biopsy are challenging or contraindicated. Such instances underscore the paramount importance of utilizing advanced imaging techniques for accurate diagnosis and treatment, especially in the complex clinical setting of immunocompromised individuals, with hematological malignancies. This case emphasizes the significant contribution of <sup>18</sup>F-FDG-PET/CT as a non-invasive diagnostic tool, enhancing patient care and enabling more effective management strategies amidst challenging medical circumstances.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"34 2","pages":"165-167"},"PeriodicalIF":0.9,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Poor Prognostic Stigma of Hepatic Superscan on 18F-FDG PET Imaging. 肝超扫18F-FDG PET显像预后不良的柱头。
IF 0.9
Molecular Imaging and Radionuclide Therapy Pub Date : 2025-06-03 DOI: 10.4274/mirt.galenos.2024.56689
Dhuha Al-Adhami, Malik Juweid, Akram Al-Ibraheem
{"title":"The Poor Prognostic Stigma of Hepatic Superscan on <sup>18</sup>F-FDG PET Imaging.","authors":"Dhuha Al-Adhami, Malik Juweid, Akram Al-Ibraheem","doi":"10.4274/mirt.galenos.2024.56689","DOIUrl":"10.4274/mirt.galenos.2024.56689","url":null,"abstract":"<p><p>Pancreatic exocrine carcinoma (PEC) is a lethal malignancy with high mortality rates because of its aggressive nature and frequent late-stage diagnosis. When histopathological diagnosis becomes unfeasible because of patient deterioration, clinicians must rely on clinical, biochemical, and radiological findings. This case report describes a 78-year-old woman with aggressive PEC visualized through <sup>18</sup>F-fluorodeoxyglucose (<sup>18</sup>F-FDG) positron emission tomography/computed tomography. The imaging revealed an intensely hypermetabolic head mass, hepatic superscan, and hypermetabolic abdominal lymphadenopathy. Despite strong clinical indicators suggesting stage IV PEC, rapid disease progression and patient demise precluded histopathological confirmation, emphasizing the poor prognosis associated with hepatic superscan in this context.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"34 2","pages":"149-151"},"PeriodicalIF":0.9,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of GLUT-1-XbaI G>T and HaeIII T>C Polymorphisms on 18F-FDG Uptake Rates. GLUT-1-XbaI G bbbbc和haeii T bbbbc多态性对18F-FDG摄取速率的影响
IF 0.9
Molecular Imaging and Radionuclide Therapy Pub Date : 2025-06-03 DOI: 10.4274/mirt.galenos.2025.93797
Melih Kısaarslan, Yasemin Adalı, Veli Kaan Aydın, Yasemin Berberoğlu, Doğangün Yüksel, Aylin Köseler
{"title":"The Effect of GLUT-1-XbaI G>T and HaeIII T>C Polymorphisms on <sup>18</sup>F-FDG Uptake Rates.","authors":"Melih Kısaarslan, Yasemin Adalı, Veli Kaan Aydın, Yasemin Berberoğlu, Doğangün Yüksel, Aylin Köseler","doi":"10.4274/mirt.galenos.2025.93797","DOIUrl":"10.4274/mirt.galenos.2025.93797","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the effects of glut polymorphisms on <sup>18</sup>Fluorine-fluorodeoxyglucose (<sup>18</sup>F-FDG) uptake rates.</p><p><strong>Methods: </strong>The <sup>18</sup>F-FDG positron emission tomography/computed tomography images and mass lesion metabolism standard uptake value maximum (SUV<sub>max</sub>) results of the patients were evaluated. Glucose transporter protein-1 (GLUT-1)-XbaI G>T (rs2754218) and HaeIII T>C (rs1385129) polymorphisms and their effects on <sup>18</sup>F-FDG uptake rates were investigated using DNA obtained from peripheral blood.</p><p><strong>Results: </strong>When the Xbal G>T genotype distribution of the patients was examined, the Xbal G/G genotype was found to be 87%, the Xbal G/T genotype 12%. The XbaI T/T phenotype was detected in only one patient (1%). In the HaeIII T>C genotype distribution, the HaeIII C/C genotype was found as 54%, the HaeIII T/C genotype as 31%, and the HaeIII T/T genotype as 15%. When the Xbal and HaeIII genotypes were examined together, the number of polymorphic genotypes was significantly higher in the lung and bronchial tumor groups compared to other cancer types.</p><p><strong>Conclusion: </strong>The presence of polymorphism in at least one of the two gene regions, in the lung-bronchial tumor group and the high SUV<sub>max</sub> value in this patient group, may indicate a change in the involvement rates.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"34 2","pages":"90-96"},"PeriodicalIF":0.9,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined 68Ga-PSMA PET/CT and mpMRI Findings Improve Tumor Localization and Biopsy Guidance in the Initial Diagnosis of Prostate Cancer. 结合68Ga-PSMA PET/CT和mpMRI结果，提高肿瘤定位和活检对前列腺癌初步诊断的指导作用。
IF 0.9
Molecular Imaging and Radionuclide Therapy Pub Date : 2025-06-03 DOI: 10.4274/mirt.galenos.2024.75547
Yavor Gramatikov, Petia Nikolova, Mihaela Ilcheva, Valentin Yotovski, Nikolay Halachev, Valeria Hadzhiyska
{"title":"Combined <sup>68</sup>Ga-PSMA PET/CT and mpMRI Findings Improve Tumor Localization and Biopsy Guidance in the Initial Diagnosis of Prostate Cancer.","authors":"Yavor Gramatikov, Petia Nikolova, Mihaela Ilcheva, Valentin Yotovski, Nikolay Halachev, Valeria Hadzhiyska","doi":"10.4274/mirt.galenos.2024.75547","DOIUrl":"10.4274/mirt.galenos.2024.75547","url":null,"abstract":"<p><p>Gallium-68 (<sup>68</sup>Ga)-prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) is a relatively new imaging modality that has already proved its role in the initial staging of prostate cancer and in biochemical recurrence following definitive primary therapy. Furthermore, emerging data several ongoing studies demonstrate its potential role in the primary diagnosis of this malignancy. We present a 67-year-old male patient with increasing clinical suspicion of prostate cancer despite a previous negative prostate gland biopsy. He was referred to our nuclear medicine department for a <sup>68</sup>Ga-PSMA PET/CT with the aim of improving tumor localization and assisting in the guidance of repeat prostate biopsy. One month before presentation of elevated prostate-specific antigen levels, he underwent multiparametric magnetic resonance imaging (mpMRI), which revealed a prostate imaging reporting and data system 4 lesion in the right lobe of the prostate gland. The MRI lesion completely matched a PRIMARY score 5 lesion registered by PET/CT. Furthermore, we detected another suspicious finding in the left lobe (PRIMARY score 4). The patient underwent PSMA PET/CT-guided MRI/ultrasonography fusion transperineal biopsy of both lesions. The latter were histologically confirmed as prostate carcinoma with a Gleason score of 3+4 =7.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"34 2","pages":"146-148"},"PeriodicalIF":0.9,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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