Molecular Imaging and Radionuclide Therapy最新文献

{"title":"Follicular Thyroid Carcinoma with Cavernous Sinus Metastasis and Perineural Spread: A Rare Manifestation of Radioiodine-refractory Disease.","authors":"Mohd Fazrin Mohd Rohani, Hamidah Lau, Jasmin Jalil, Razmin Ghazali, Siti Zarina Amir Hassan","doi":"10.4274/mirt.galenos.2026.55088","DOIUrl":"10.4274/mirt.galenos.2026.55088","url":null,"abstract":"<p><p>Cavernous sinus metastasis from follicular thyroid carcinoma (FTC) is exceedingly rare and typically indicates advanced, radioiodine-refractory disease. We report a 37-year-old man with minimally invasive FTC who was treated with total thyroidectomy, neck dissection, and cumulative radioiodine therapy totaling 720 mCi for persistent iodine-avid disease. Four years later, he developed progressive left-sided palsies of cranial nerves III, IV, and VI. Imaging revealed a cavernous sinus mass with orbital apex extension and perineural spread. Serum thyroglobulin was markedly elevated (>500 ng/mL), whereas diagnostic radioiodine scintigraphy demonstrated no uptake, a finding consistent with dedifferentiated disease. Biopsy confirmed metastatic FTC. The patient received external beam radiotherapy and systemic therapy with lenvatinib; however, the disease progressed, and he died 16 months after the diagnosis of cavernous sinus metastasis. This case highlights the aggressive potential of FTC, the limitations of radioiodine imaging in dedifferentiated disease, and the poor prognosis associated with skull-base metastases despite multimodal therapy.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" ","pages":"252-255"},"PeriodicalIF":0.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148303407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of ¹⁸F-FDG PET/CT Radiomics with Tumor Molecular Features in Breast Cancer.","authors":"Büşra Aydur Püren, Semra Usta, Yavuz Sami Salihoğlu, Rabiye Uslu Erdemir","doi":"10.4274/mirt.galenos.2026.09471","DOIUrl":"10.4274/mirt.galenos.2026.09471","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to investigate the potential relationship between radiomic features extracted from ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography (PET)/computed tomography (CT) images of patients with breast cancer and molecular markers including estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER-2) and Ki-67.</p><p><strong>Methods: </strong>Radiomic features were obtained via an open-source software (LIFEx) from ¹⁸F-FDG PET/CT images of 162 patients with histopathologically confirmed breast cancer. In order to examine the association between each molecular marker and radiomic features, machine learning models were developed seperately using the Python software. After the data were divided into test and training subsets, features were selected and scaled. Using the selected features, five different machine learning models (Random Forest, XGBoost, Support Vector Machine, Logistic Regression and Naive Bayes) were established and their performance was evaluated based on accuracy, sensitivity, specificity, F1 score, balanced accuracy, MCC and area under the curve (AUC) the receiver operating characteristic curve.</p><p><strong>Results: </strong>For HER-2 status, the model yielded an AUC of 0.76, a balanced accuracy of 0.76, a sensitivity of 62.5% and a specificity of 90.0%. For ER, PR and Ki-67 status, AUC values were 0.59, 0.55, 0.60, balanced accuracies were 0.65, 0.61, 0.62, sensitivities were 96.6%, 81.8%, 68.4% and specificities were 33.3%, 40.0%, 55.2% respectively.</p><p><strong>Conclusion: </strong>In this study, radiomic features derived from ¹⁸F-FDG PET/CT images demonstrated poor or non-discriminatory performance in the assessment of ER, PR and Ki-67 status. Although a preliminary signal of an association was observed for HER-2 status, this finding should be considered hypothesis-generating only due to the low number of HER-2-positive cases in the test subset and the lack of independent external validation. In larger cohorts prospective, multicenter studies are needed to validate this potential association.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"35 3","pages":"166-174"},"PeriodicalIF":0.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149116306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffuse Gastric Uptake and Metabolic Superscan in the Patient with Multiple Myeloma.","authors":"Gündüzalp Buğrahan Babacan, Ömer Şeker, Gülçin Baş, Hüseyin Aksoy, Ferah Taran, Ediz Beyhan","doi":"10.4274/mirt.galenos.2026.43765","DOIUrl":"10.4274/mirt.galenos.2026.43765","url":null,"abstract":"<p><p>Metastatic calcification is characterized by abnormal deposition of calcium in extraosseous tissues resulting from disruption of calcium-phosphorus homeostasis. It occurs without tissue damage and is usually seen in normal organs. It is most commonly observed in patients with chronic renal failure, paraneoplastic hypercalcemia, and vitamin D intoxication. Metabolic superscan is characterized by diffusely increased skeletal activity with suppressed renal visualization, often without soft-tissue involvement. This pattern reflects altered radiotracer biodistribution secondary to severe metabolic bone turnover. We report a case of multiple myeloma in which diffuse ^99mTc-MDP uptake was observed in the stomach on a metabolic superscan.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" ","pages":"248-251"},"PeriodicalIF":0.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148303341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Exceptional Presentation of Hutch Diverticulum on Bone Scintigraphy.","authors":"Laila El Asraoui, Hasnae Guerrouj, Ayat Mouaden, Imad Ghfir","doi":"10.4274/mirt.galenos.2026.37233","DOIUrl":"10.4274/mirt.galenos.2026.37233","url":null,"abstract":"<p><p>Hutch diverticulum (HD) is a rare congenital condition characterized by the herniation of the bladder’s mucosa and submucosa through the detrusor muscle fibers, encountered more commonly in children. An association between HD and situs inversus totalis (SIT) in an elderly patient has not been reported previously in the literature. We present the case of a 70-year-old male referred for routine bone scintigraphy as part of staging for lung carcinoma; thoraco-abdomino-pelvic computed tomography confirmed the staging and revealed a total transposition of the thoracic and abdominal organs, confirming SIT. This case highlights the exceptional association of HD and SIT, which was discovered incidentally in an elderly patient during metastatic staging for lung cancer. It underscores the importance of careful interpretation of scintigraphic findings, particularly when unusual radiotracer uptake is observed.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" ","pages":"267-269"},"PeriodicalIF":0.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined Maximum Tolerated Activity and Lesion-based Dosimetry for Personalized Radioiodine Therapy in Metastatic Differentiated Thyroid Carcinoma: An Early Institutional Experience.","authors":"Nadiah Abd Razak, Hwee Meng Joanne Lee, Adeline Mathew, Siti Zarina Amir Hassan, Haizana Hairuman","doi":"10.4274/mirt.galenos.2026.18863","DOIUrl":"10.4274/mirt.galenos.2026.18863","url":null,"abstract":"<p><strong>Objectives: </strong>Empirical fixed-activity radioiodine (RAI) therapy remains widely used in differentiated thyroid carcinoma (DTC), despite substantial inter-patient variability in iodine kinetics. Pre-therapeutic dosimetry offers a personalised approach by estimating radiation exposure to organs at risk as well as to tumour lesions. To describe our institutional experience with combined maximum tolerated activity (MTA) and lesion-based dosimetry in patients with metastatic or recurrent DTC, and to evaluate its impact on clinical decision-making.</p><p><strong>Methods: </strong>A retrospective case series of six DTC patients undergoing pre-therapeutic Iodine-131dosimetry over two years was recorded. Whole-body and blood-based dosimetry were used to calculate MTA, while lesion-based dosimetry was calculated via estimated absorbed lesion-based dose per administered activity (LDpA). Treatment decisions were made following multidisciplinary discussion.</p><p><strong>Results: </strong>Five patients completed the dosimetric evaluation. In one patient with high tumour burden, MTA and LDpA provided complementary safety and efficacy data, although facility constraints had limited the final administered activity. In three patients with small-volume inoperable cervical nodal disease, LDpA was <5 Gy/GBq, predicting a limited therapeutic benefit thus preventing further ineffective RAI therapy administration. In another patient with osseous metastases, prior high cumulative RAI exposure as well as low LDpA indicated limited benefit in further high dose RAI therapy, highlighting the importance of early dosimetric assessment.</p><p><strong>Conclusion: </strong>Personalised dosimetry with combined safety-based and lesion-based approach may enhance the therapeutic precision in patients with advanced DTC. However, careful patient selection is essential in maximising clinical utility.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"35 3","pages":"211-222"},"PeriodicalIF":0.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149116225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pearls and Pitfalls of ¹⁸F-FDG PET/CT for Suspected Alzheimer's Disease in Patient with Down Syndrome.","authors":"Elife Akgün, Satoshi Minoshima","doi":"10.4274/mirt.galenos.2026.13285","DOIUrl":"10.4274/mirt.galenos.2026.13285","url":null,"abstract":"<p><p>Dementia in individuals with Down syndrome (DS) is the leading cause of early-onset cognitive decline occurring before the age of 50. However, establishing an accurate diagnosis remains particularly challenging due to pre-existing intellectual disability, variability in baseline cognitive function, and the limited reliability of standard neuropsychological assessments. ¹⁸F-fluorodeoxyglucose positron emission tomography (¹⁸F-FDG PET) plays a critical role in identifying underlying neurodegenerative processes and supporting the diagnosis. We present a case of DS with multiple known and unknown pathologies identified on brain ¹⁸F-FDG PET and a confirmed diagnosis of early-onset mild Alzheimer's disease.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" ","pages":"256-259"},"PeriodicalIF":0.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148303322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"⁶⁸Ga-FAPI Avidity in Fat Necrosis and Adrenal Adenoma: Expanding the Spectrum of Benign Pitfalls in Oncologic Imaging.","authors":"Serin Moghrabi, Raghad Mohammad Al-Houwari, Baraa Alsyouf, Akram Al-Ibraheem","doi":"10.4274/mirt.galenos.2026.85619","DOIUrl":"10.4274/mirt.galenos.2026.85619","url":null,"abstract":"<p><p>Fat necrosis, a benign postoperative process related to tissue injury and repair, may demonstrate variable findings on functional imaging. We report a case of postoperative fat necrosis following pancreaticoduodenectomy showing intense ⁶⁸Ga-FAPI uptake in the absence of significant ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) avidity. Surveillance ¹⁸F-FDG positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) demonstrated only mild activity within the surgical bed maximum standard uptake value (SUV_max 2.4), while subsequent ⁶⁸Ga-FAPI PET/CT revealed marked uptake corresponding to fat necrosis SUV_max 9.9, consistent with pronounced fibroblast activation during postoperative healing. Additionally, a benign left adrenal adenoma showed low ¹⁸F-FDG uptake and only minimal ⁶⁸Ga-FAPI avidity (SUV_max 2.3), reflecting minimal stromal activation. This case highlights the tracer discordance between ¹⁸F-FDG and ⁶⁸Ga-FAPI in fat necrosis and underscores the importance of correlating ⁶⁸Ga-FAPI findings with surgical history and anatomic imaging to ensure accurate interpretation.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" ","pages":"274-279"},"PeriodicalIF":0.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148303350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Cavitary Lung Lesions with ¹⁸F-FDG PET/CT: Differentiating Benign from Malignant Lesions.","authors":"Nur Aydınbelge Dizdar, Ebru Tatcı, Ülkü Nur Derya, Özlem Özmen","doi":"10.4274/mirt.galenos.2026.23334","DOIUrl":"10.4274/mirt.galenos.2026.23334","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to analyze ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) features to differentiate benign from malignant pulmonary cavitary lesions.</p><p><strong>Methods: </strong>A total of 76 patients with cavitary lung lesions who underwent ¹⁸F-FDG PET/CT imaging were retrospectively analyzed. Patient demographics, histopathological findings, cavitary lesion morphology, CT characteristics, and maximum standard uptake value (SUV_max) of lesions were recorded. Cavitary lesions were classified as benign or malignant and further subdivided by maximum wall thickness into two groups: ≤15 mm and >15 mm. Histopathological results, clinical follow-up, or both were used as the reference standard for lesion classification.</p><p><strong>Results: </strong>Among 76 patients (mean age, 63.4 years), 31 (40.8%) had benign disease and 45 (59.2%) had malignant disease. Malignant lesions were observed at older ages and exhibited significantly greater lesion size, wall thickness, and SUV_max than those in benign lesions (p<0.05 for all). There were no significant differences between the malignant and benign groups regarding sex, lesion localization, air-fluid levels, or pleural effusion (p>0.05 for all). Peripheral consolidation, multiple cavitary lesions, and tree-in-bud pattern were significantly more prevalent in benign lesions than in malignant lesions (p<0.05 for all). In lesions with a maximum wall thickness ≤15 mm, SUV_max was significantly higher in malignant lesions than in benign lesions (mean values, 9.81 vs. 5.28; p<0.05). Malignant lesions with a maximum wall thickness >15 mm demonstrated higher SUV_max values (mean 18.37 vs. 10.45; p<0.05). SUV_max was independently associated with malignancy (odds ratio: 1.237, p=0.017) and showed the best diagnostic performance (area under the curve=0.866; cut-off 8.58, sensitivity 80%, specificity 77%).</p><p><strong>Conclusion: </strong>The morphological characteristics of pulmonary cavitary lesions, associated parenchymal findings, and ¹⁸F-FDG uptake patterns on PET/CT provide valuable information for distinguishing between benign and malignant lesions. In this study, SUV_max demonstrated the highest diagnostic performance. The combined evaluation of metabolic and morphological parameters can enhance diagnostic accuracy and support the clinical decision-making process, thereby contributing to the optimal management of patients.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" ","pages":"157-165"},"PeriodicalIF":0.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148431296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Performance of ¹⁸F-FDG PET/CT and ⁶⁸Ga-FAPI PET/CT in TENIS Syndrome in Treated Differentiated Thyroid Carcinoma.","authors":"Jayantilal Bhagirath Bhad, Manjit Sarma, Usha Menon, Ramkesh R, Parvathy Pavithran, Awiral Saxena, Sanjana Sajeev, Venkata Sai Ram B. Reddy, Padma Subramanyam, P. Shanmuga Sundaram","doi":"10.4274/mirt.galenos.2026.80037","DOIUrl":"10.4274/mirt.galenos.2026.80037","url":null,"abstract":"<p><strong>Objectives: </strong>Thyroglobulin-elevated negative iodine scintigraphy (TENIS) syndrome presents a significant diagnostic challenge in the management of differentiated thyroid carcinoma (DTC). Although ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) is the established imaging modality for detecting presence of structural disease, Gallium-68 (⁶⁸Ga)-fibroblast activation protein inhibitor (FAPI) PET/CT, which targets the tumor stroma, represents a promising new alternative. This study directly compared the lesion detection capabilities of both tracers in patients with TENIS.</p><p><strong>Methods: </strong>In this prospective single-center study (2021-2024), 22 patients with TENIS syndrome underwent both ¹⁸F-FDG and ⁶⁸Ga-FAPI PET/CT scans within a 7-day interval of each other. Lesion detectability and maximum standardized uptake values (SUV_max) were compared between the two modalities. Lesions were validated using histopathology or cytopathology, biochemical response to empirical ¹³¹I therapy, imaging correlation or progression, and clinical progression methods.</p><p><strong>Results: </strong>Among 22 patients (median age 43.5 years, 90% with papillary carcinoma), ¹⁸F-FDG was positive in 23/33 cervical lymph nodes, whereas ⁶⁸Ga-FAPI was positive in 14/33 lymph nodes. Fourteen lymph nodes were positive on both modalities with comparable SUV_max (median ¹⁸F-FDG 3.3 vs. ⁶⁸Ga-FAPI 3.6, p=0.689). All local recurrences in thyroid bed (n=4) were ¹⁸F-FDG-positive, whereas only 3 of the local recurrences were ⁶⁸Ga-FAPI-positive. Distant metastases (lung and bone) showed similar detection rates.</p><p><strong>Conclusion: </strong>¹⁸F-FDG PET/CT demonstrates superior lesion detectability, particularly for cervical lymph nodes, in TENIS syndrome. ⁶⁸Ga-FAPI PET/CT provides complementary information with comparable semiquantitative uptake in detected lesions but with lower overall detection. ¹⁸F-FDG PET/CT remains the preferred imaging modality for comprehensive disease evaluation in patients with radioactive iodine-refractory DTC.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" ","pages":"183-193"},"PeriodicalIF":0.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148799190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PET/CT Identifies Pubic Melorheostosis with High ⁶⁸Ga-PSMA Uptake in a Patient with Prostate Cancer.","authors":"Deya Aldeen Sweedat, Ahmed Saad Abdlkadir, Akram Al-Ibraheem","doi":"10.4274/mirt.galenos.2026.62144","DOIUrl":"10.4274/mirt.galenos.2026.62144","url":null,"abstract":"<p><p>Melorheostosis, a rare benign bone disorder marked by cortical thickening and irregular hyperostosis, typically affects peripheral bones but can also involve the axial skeleton. Though various molecular imaging radiotracers have been used to evaluate this condition, there are no previous reports of positive ⁶⁸Ga-prostate-specific membrane antigen positron emission tomography/computed tomography (⁶⁸Ga-PSMA PET/CT) findings in melorheostosis. This case presents a 70-year-old man with metastatic prostate cancer whose ⁶⁸Ga-PSMA PET/CT scan revealed intense ⁶⁸Ga-PSMA uptake in pubic melorheostosis seen on magnetic resonance imaging. The case highlights the possibility of ⁶⁸Ga-PSMA-avid melorheostosis and suggests ⁶⁸Ga-PSMA PET/CT may have a role in the evaluation of melorheostosis.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" ","pages":"260-262"},"PeriodicalIF":0.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}