Dermatopathology最新文献_第7页

The Effect of Bacillus coagulans Induced Interactions among Intestinal Bacteria, Metabolites, and Inflammatory Molecules in Improving Natural Skin Aging. 凝结芽孢杆菌诱导肠道细菌、代谢产物和炎症分子之间的相互作用在改善自然皮肤衰老中的作用。

IF 1.9

Dermatopathology Pub Date : 2023-09-28 DOI: 10.3390/dermatopathology10040037

Keiichi Hiramoto, Sayaka Kubo, Keiko Tsuji, Daijiro Sugiyama, Yasutaka Iizuka, Hideo Hamano

{"title":"The Effect of Bacillus coagulans Induced Interactions among Intestinal Bacteria, Metabolites, and Inflammatory Molecules in Improving Natural Skin Aging.","authors":"Keiichi Hiramoto, Sayaka Kubo, Keiko Tsuji, Daijiro Sugiyama, Yasutaka Iizuka, Hideo Hamano","doi":"10.3390/dermatopathology10040037","DOIUrl":"10.3390/dermatopathology10040037","url":null,"abstract":"Background: Lactic acid bacteria consumption serves several health benefits to humans. However, their effect on natural skin aging is still unclear.Methods: This study examined the effects of skin naturalization (particularly skin drying) by administering a spore-bearing lactic acid bacteria (Bacillus coagulans) in mice for 2 years.Results: B. coagulans administration improved the natural skin of mice and significantly increased proportions of the genera Bacteroides and Muribaculum, among other intestinal bacteria. As metabolites, increases in nicotinic acid, putrescin, and pantothenic acid levels and a decrease in choline levels were observed. Increased hyaluronic acid, interleukin-10, and M2 macrophage levels indicate aging-related molecules in the skin. Intestinal permeability was also suppressed. Thus, these changes together improved natural skin aging.Conclusions: This study revealed that B. coagulans administration improved the natural skin aging in mice. This enhancement might be induced by the interaction of alterations in intestinal flora, metabolites, or inflammatory substances.","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":"10 4","pages":"287-302"},"PeriodicalIF":1.9,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49692941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clear Cell Acanthoma with Malignant Cytologic Features: A Case Report and Review of the Literature. 具有恶性细胞学特征的透明细胞棘瘤1例报告及文献复习。

IF 1.9

Dermatopathology Pub Date : 2022-10-20 DOI: 10.3390/dermatopathology9040041

Gabriella Melson, Elie Saliba, Shreya Patel, Richard Eisen, Candice E Brem

引用次数: 1

Reactive Epidermal Hyperplasia and Angiogenesis of the Rear (REAR): A Proposed Unifying Name for Senile Gluteal Dermatosis and Prurigiform Angiomatosis. 后侧反应性表皮增生和血管生成:老年性臀皮肤病和瘙痒样血管瘤病的统一名称。

IF 1.9

Dermatopathology Pub Date : 2022-10-13 DOI: 10.3390/dermatopathology9040040

Michelle Weiting Liang, Joel H L Lim, Hui Yi Chia, Shang-Ian Tee, Joyce S S Lee

引用次数: 1

Dermatopathology 皮肤病理学

IF 1.9

Dermatopathology Pub Date : 2022-10-01 DOI: 10.1007/978-3-030-82820-2

Werner Kempf, Markus Hantschke, H. Kutzner

引用次数: 0

A Rare Case of Blastic Plasmacytoid Dendritic Cell Neoplasm in a Child Mimicking Lymphoma/Leukemia Cutis. 一例罕见的模仿淋巴瘤/白血病皮肤的儿童成母浆细胞样树突状细胞肿瘤。

IF 1.9

Dermatopathology Pub Date : 2022-09-30 DOI: 10.3390/dermatopathology9040038

Phanitchanat Phusuphitchayanan, Voraphol Vejjabhinanta, Chayamon Takpradit, Poonnawis Sudtikoonaseth, Manasmon Chairatchaneeboon, Thamonpan Kiatvichukul, Sanya Sukpanichnant

{"title":"A Rare Case of Blastic Plasmacytoid Dendritic Cell Neoplasm in a Child Mimicking Lymphoma/Leukemia Cutis.","authors":"Phanitchanat Phusuphitchayanan, Voraphol Vejjabhinanta, Chayamon Takpradit, Poonnawis Sudtikoonaseth, Manasmon Chairatchaneeboon, Thamonpan Kiatvichukul, Sanya Sukpanichnant","doi":"10.3390/dermatopathology9040038","DOIUrl":"https://doi.org/10.3390/dermatopathology9040038","url":null,"abstract":"Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare tumor that affects elderly individuals and presents a poor prognosis. Skin is the most common site of involvement, accounting for 89% of the cases. Extracutaneous organs, especially bone marrow, lymph nodes, and peripheral blood, can be involved at the time of diagnosis. We report a case of BPDCN in a child, presenting with a cutaneous lesion mimicking lymphoma or leukemia cutis. The histologic findings revealed a dense diffuse infiltration by monomorphic agranular medium-sized blast cells with sparing of the grenz zone, whose first immunophenotypic profile raised the possibility of diagnosing B lymphoblastic lymphoma or leukemia. However, the absence of CD10 expression and strongly positive expression for CD4, CD56, CD45RA, and the plasmacytoid dendritic cell-associated antigens, including CD123, supported the definite diagnosis of BPDCN. The patient responded well to a systemic combination chemotherapy regimen, modified from the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) protocol for anaplastic large cell lymphoma (ALCL), that differed from the established recommendation using ALL protocol. Owing to the patient's excellent treatment outcome, this regimen could represent an effective alternative regimen for BPDCN in children.","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":" ","pages":"321-326"},"PeriodicalIF":1.9,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40568287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Cutaneous Involvement of Extranodal NK/T Cell Lymphoma, Nasal Type, a Clinical and Histopathological Mimicker of Various Skin Diseases. 结外NK/T细胞淋巴瘤的皮肤侵犯，鼻型，各种皮肤病的临床和组织病理学模拟者。

IF 1.9

Dermatopathology Pub Date : 2022-09-09 DOI: 10.3390/dermatopathology9030037

Preeyawat Ngamdamrongkiat, Sanya Sukpanichnant, Manasmon Chairatchaneeboon, Archrob Khuhapinant, Panitta Sitthinamsuwan

{"title":"Cutaneous Involvement of Extranodal NK/T Cell Lymphoma, Nasal Type, a Clinical and Histopathological Mimicker of Various Skin Diseases.","authors":"Preeyawat Ngamdamrongkiat, Sanya Sukpanichnant, Manasmon Chairatchaneeboon, Archrob Khuhapinant, Panitta Sitthinamsuwan","doi":"10.3390/dermatopathology9030037","DOIUrl":"https://doi.org/10.3390/dermatopathology9030037","url":null,"abstract":"Background: Extranodal NK/T cell lymphoma, nasal type (ENK/T) with cutaneous involvement has various histopathological findings and diverse clinical manifestations.Methods: A retrospective study of cutaneous involvement of ENK/T lymphoma between 2006 and 2018 was conducted.Results: Twenty-two cases were eligible for this study. Twelve cases could be proven as secondary cutaneous involvement by ENK/T lymphoma, while the remaining could not be confirmed as primary cutaneous ENK/T lymphoma. The histopathological patterns included dermal and subcutaneous nodular infiltration pattern in 11/22 cases (50%), lobular panniculitis pattern in 6/22 cases (27.3%), interface dermatitis pattern in 4/22 cases (18.2%), and granulomatous dermatitis pattern in 1/22 case (4.5%). The median follow-up was 18.3 months. Overall, the one-year and five-year survival rates were 31.3% and 13.3%, respectively.Conclusions: A variety of histopathological patterns of cutaneous involvement by ENK/T lymphoma should be differentiated from other cutaneous lymphomas, dermatitis, and infection. When atypical medium or large-sized lymphoid cells are encountered within skin lesions, pathologists should realize these lesions can be ENK/T lymphoma, especially in cases with coexisting tumor necrosis or angioinvasion. A complete evaluation of the upper aerodigestive tract is mandatory to identify the occult primary site of ENK/T lymphoma before establishing primary cutaneous ENK/T lymphoma.","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":" ","pages":"307-320"},"PeriodicalIF":1.9,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33469847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

In Memoriam-Martin C. Mihm, Jr. 纪念马丁·c·米姆

IF 1.9

Dermatopathology Pub Date : 2022-09-08 DOI: 10.3390/dermatopathology9030036

Thomas Kupper, Adriano Piris, Daniela Kroshinsky, Gürkan Kaya

引用次数: 0

A Case of IgG and IgA Anti-Laminin-332 Antibody-Positive Mucous Membrane Pemphigoid with IgG and IgA Anti-Envoplakin and Anti-Periplakin Antibodies. IgG和IgA抗laminin -332抗体阳性的粘膜类天疱疮伴IgG和IgA抗envoplakin和抗periplakin抗体1例。

IF 1.9

Dermatopathology Pub Date : 2022-08-08 DOI: 10.3390/dermatopathology9030034

Yoshiaki Matsushima, Masako Kitano, Daisuke Hayashi, Hiroyuki Goto, Mako Mine, Takeshi Yokoe, Makoto Kondo, Koji Habe, Yuji Toiyama, Takashi Hashimoto, Daisuke Tsuruta, Kazuhiko Takeuchi, Keiichi Yamanaka

{"title":"A Case of IgG and IgA Anti-Laminin-332 Antibody-Positive Mucous Membrane Pemphigoid with IgG and IgA Anti-Envoplakin and Anti-Periplakin Antibodies.","authors":"Yoshiaki Matsushima, Masako Kitano, Daisuke Hayashi, Hiroyuki Goto, Mako Mine, Takeshi Yokoe, Makoto Kondo, Koji Habe, Yuji Toiyama, Takashi Hashimoto, Daisuke Tsuruta, Kazuhiko Takeuchi, Keiichi Yamanaka","doi":"10.3390/dermatopathology9030034","DOIUrl":"https://doi.org/10.3390/dermatopathology9030034","url":null,"abstract":"A 76-year-old Japanese man presented with a 6-year history of a sore throat. He was treated at several clinics without any improvement before being referred to us. Physical examination revealed widespread erosions and ulcers from the palate to the larynx. Approximately 25 × 15 mm in size, erosive lesions were present on the retroauricular regions, forearms, and glans penis. Pseudomembranous conjunctivitis was also observed. The skin biopsy revealed a partial cleft formation below the epidermis, suggesting subepidermal bullous disease. Immuno-serological tests were negative for anti-desmoglein 1 (Dsg1), anti-Dsg3, anti-BP180, and anti-BP230 antibodies by ELISAs. A whole-body examination revealed gastric cancer. The possibility of mucous membrane pemphigoid (MMP) or paraneoplastic pemphigus (PNP) was considered. Indirect immunofluorescence using rat bladders showed positive IgG reactivity with cell surfaces on the transitional epithelia. Immunoblotting using recombinant proteins of laminin-332 showed both IgG and IgA reactivities with laminin-α3, and immunoblotting using normal human epidermal extract showed double-positive reactivities with envoplakin and periplakin for both IgG and IgA antibodies. Based on the clinical and histopathological features and results of various immuno-serological tests, our case was diagnosed as anti-laminin-332-type MMP with serological findings of PNP. Twenty days after laparoscopic gastrectomy, treatment with oral methylprednisolone 32 mg/day was initiated, and mucosal and skin lesions improved.","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":" ","pages":"287-291"},"PeriodicalIF":1.9,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40631742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Blisters and Milia around the Peritoneal Dialysis Catheter: A Case of Localized Bullous Pemphigoid. 腹膜透析导管周围的水疱和粟粒:局限性大疱性类天疱疮1例。

IF 1.9

Dermatopathology Pub Date : 2022-08-04 DOI: 10.3390/dermatopathology9030033

Andrea Michelerio, Carlo Tomasini

引用次数: 1

Genital Folliculosebaceous Cystic Hamartoma: A Case Report and Concise Review of the Literature. 生殖毛囊皮脂腺囊性错构瘤1例报告及文献综述。

IF 1.9

Dermatopathology Pub Date : 2022-08-01 DOI: 10.3390/dermatopathology9030032

Maged Daruish, Mona Abdel-Halim Ibrahim

引用次数: 0