DermatopathologyPub Date : 2022-01-26DOI: 10.3390/dermatopathology9010006
{"title":"Acknowledgment to Reviewers of Dermatopathology in 2021","authors":"","doi":"10.3390/dermatopathology9010006","DOIUrl":"https://doi.org/10.3390/dermatopathology9010006","url":null,"abstract":"Rigorous peer-reviews are the basis of high-quality academic publishing [...]","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":"9 1","pages":"35 - 35"},"PeriodicalIF":1.9,"publicationDate":"2022-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46756777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DermatopathologyPub Date : 2022-01-17DOI: 10.3390/dermatopathology9010005
Paola Lara-Valencia, Anna Ybo, Anna Coter
{"title":"Fibroblastic Connective Tissue Nevus Mimicking Lipoma on Ultrasound: Case Report and Brief Review.","authors":"Paola Lara-Valencia, Anna Ybo, Anna Coter","doi":"10.3390/dermatopathology9010005","DOIUrl":"https://doi.org/10.3390/dermatopathology9010005","url":null,"abstract":"<p><p>Fibroblastic connective tissue nevus (FCTN) is a rare, benign, and recently described dermal mesenchymal lesion characterized by CD34-positive spindle cells. We present a case of FCTN on the upper back of a 9-month-old boy who was diagnosed with a benign lipoma by ultrasound.</p>","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":"9 1","pages":"32-34"},"PeriodicalIF":1.9,"publicationDate":"2022-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39857702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DermatopathologyPub Date : 2022-01-16DOI: 10.3390/dermatopathology9010004
Giorgio Annessi, Emanuele Annessi
{"title":"Annular Lichenoid Dermatitis (of Youth).","authors":"Giorgio Annessi, Emanuele Annessi","doi":"10.3390/dermatopathology9010004","DOIUrl":"https://doi.org/10.3390/dermatopathology9010004","url":null,"abstract":"<p><p>About 20 years after its first description, Annular Lichenoid Dermatitis of Youth (ALDY) is recognized as a distinctive lichenoid dermatosis with specific clinical and histological features. The disease occurs mostly in young persons all over the world, runs a chronic course, and has an obscure etiopathogenesis. Clinically, lesions consist of persistent, asymptomatic erythematous macules and round-oval annular patches with a red-violaceous non-scaling border and central hypopigmentation, mostly localized on the groin and flanks. Histology shows a peculiar lichenoid dermatitis characterized by irregular epidermal hyperplasia with an alternation of thinned and quadrangular rete ridges and a dense band-like lichenoid infiltrate of lymphocytes in the papillary dermis. Typically, there is infiltration of lymphocytes into the lower epidermal layers with massive necrosis/apoptosis of keratinocytes, which is limited to the tips of rete ridges. Dermal lymphocytes are usually CD3<sup>+</sup>, CD4<sup>+</sup>, while most of the intraepidermal T cells are CD8<sup>+</sup>. Analysis of TCR-γ-chain gene rearrangement displayed polyclonality in all cases examined. Differential diagnosis mainly includes morphea, mycosis fungoides, annular erythemas and inflammatory lesions of vitiligo. Topical corticosteroids and topical tacrolimus represent the most effective drugs for ALDY treatment.</p>","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":"9 1","pages":"23-31"},"PeriodicalIF":1.9,"publicationDate":"2022-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39858486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DermatopathologyPub Date : 2022-01-10DOI: 10.3390/dermatopathology9010003
Angelo Cassisa, Margherita Vannucchi
{"title":"Morphea Profunda with Tertiary Lymphoid Follicles: Description of Two Cases and Review of the Literature.","authors":"Angelo Cassisa, Margherita Vannucchi","doi":"10.3390/dermatopathology9010003","DOIUrl":"https://doi.org/10.3390/dermatopathology9010003","url":null,"abstract":"<p><p>Morphea profunda or subcutaneous (deep) morphea is a variant of localized morphea, characterized by one or more ill-defined, deep sclerotic plaque. Preferential sites are the abdomen, trunk, sacral area, or extremities. The presence of hyperplastic lymphoid follicles in the context of the sclerotic bands of morphea is rarely described. Localized scleroderma is sustained by a profibrotic inflammatory profile. Transforming growth factor-β (TGF-β), an imbalance between functional subclasses of T-lymphocytes (innate immune cells) has a role in activate collagen deposition. In this case report, we present two cases of morphea profunda with lymphoid follicular hyperplasia. A systematic review of the literature on the pathophysiology of localized scleroderma is also presented, with particular reference to the presence of lymphoid structures.</p>","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":"9 1","pages":"17-22"},"PeriodicalIF":1.9,"publicationDate":"2022-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39857105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DermatopathologyPub Date : 2022-01-01DOI: 10.1007/978-3-030-82820-2_16
W. Kempf, M. Hantschke, H. Kutzner
{"title":"Drug Reactions","authors":"W. Kempf, M. Hantschke, H. Kutzner","doi":"10.1007/978-3-030-82820-2_16","DOIUrl":"https://doi.org/10.1007/978-3-030-82820-2_16","url":null,"abstract":"","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":"38 2","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50980353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DermatopathologyPub Date : 2022-01-01DOI: 10.1007/978-3-030-82820-2_1
W. Kempf, M. Hantschke, H. Kutzner
{"title":"Principles of Diagnosis","authors":"W. Kempf, M. Hantschke, H. Kutzner","doi":"10.1007/978-3-030-82820-2_1","DOIUrl":"https://doi.org/10.1007/978-3-030-82820-2_1","url":null,"abstract":"","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":"158 2","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50980093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DermatopathologyPub Date : 2022-01-01DOI: 10.1007/978-3-030-82820-2_20
W. Kempf, M. Hantschke, H. Kutzner
{"title":"Epidermal Hamartomas and Neoplasms","authors":"W. Kempf, M. Hantschke, H. Kutzner","doi":"10.1007/978-3-030-82820-2_20","DOIUrl":"https://doi.org/10.1007/978-3-030-82820-2_20","url":null,"abstract":"","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":"34 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50980456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DermatopathologyPub Date : 2022-01-01DOI: 10.1007/978-3-030-82820-2_5
W. Kempf, M. Hantschke, H. Kutzner
{"title":"Epidermis: Spongiosis, Acanthosis and Hyperparakeratosis","authors":"W. Kempf, M. Hantschke, H. Kutzner","doi":"10.1007/978-3-030-82820-2_5","DOIUrl":"https://doi.org/10.1007/978-3-030-82820-2_5","url":null,"abstract":"","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":"38 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50980629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DermatopathologyPub Date : 2022-01-01DOI: 10.1007/978-3-030-82820-2_10
W. Kempf, M. Hantschke, H. Kutzner
{"title":"Dermis Granulomatous Inflammation","authors":"W. Kempf, M. Hantschke, H. Kutzner","doi":"10.1007/978-3-030-82820-2_10","DOIUrl":"https://doi.org/10.1007/978-3-030-82820-2_10","url":null,"abstract":"","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":"6 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50980150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DermatopathologyPub Date : 2022-01-01DOI: 10.1007/978-3-030-82820-2_9
W. Kempf, M. Hantschke, H. Kutzner
{"title":"Dermis Vascular Disorders","authors":"W. Kempf, M. Hantschke, H. Kutzner","doi":"10.1007/978-3-030-82820-2_9","DOIUrl":"https://doi.org/10.1007/978-3-030-82820-2_9","url":null,"abstract":"","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":"101 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50980692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}