Dermatopathology最新文献_第9页

Peri-Umbilical Lymphangioma Circumscriptum Associated with Intra-Abdominal Lymphatic Malformations 脐周淋巴管瘤包皮环切术并发腹腔内淋巴畸形

IF 1.9

Dermatopathology Pub Date : 2019-04-01 DOI: 10.1159/000496387

Bhavna P Singh, K. Hoosen

引用次数: 1

A Case of Compound Nevus with Intradermal Pseudoglandular Features: A Rare Variant and Possible Pitfall 具有皮内假腺特征的复合痣1例:一种罕见的变异和可能的陷阱

IF 1.9

Dermatopathology Pub Date : 2019-04-01 DOI: 10.1159/000500400

M. Maillard, Listette Stucki, G. Kaya

引用次数: 0

Emergomycosis (Emergomyces africanus) in Advanced HIV Disease 晚期HIV疾病中的新兴菌病(非洲新兴菌

IF 1.9

Dermatopathology Pub Date : 2019-04-01 DOI: 10.1159/000495405

N. Govender, W. Grayson

引用次数: 17

Multiple Eruptive Sebaceous Hyperplasia Secondary to Cyclosporin in a Patient with Bone Marrow Transplantation 骨髓移植患者继发于环孢素的多发爆发性皮脂腺增生

IF 1.9

Dermatopathology Pub Date : 2016-11-12 DOI: 10.1159/000452330

Bégonia Cortès, G. Kaya

引用次数: 2

T-Cadherin Expression in the Epidermis and Adnexal Structures of Normal Skin t -钙粘蛋白在正常皮肤表皮和附件结构中的表达

IF 1.9

Dermatopathology Pub Date : 2016-10-21 DOI: 10.1159/000451024

S. Buechner, P. Erne, T. Resink

{"title":"T-Cadherin Expression in the Epidermis and Adnexal Structures of Normal Skin","authors":"S. Buechner, P. Erne, T. Resink","doi":"10.1159/000451024","DOIUrl":"https://doi.org/10.1159/000451024","url":null,"abstract":"Background: T-cadherin is an atypical glycosylphosphatidylinositol-anchored member of the cadherin superfamily of adhesion molecules. The role of T-cadherin in biology of the skin is poorly understood. Expression of T-cadherin in basal keratinocytes and dermal blood vessels of the healthy epidermis has been demonstrated, but studies on expression in skin appendages are rare. Methods: We conducted an immunohistochemical analysis of T-cadherin expression in the epidermis and adnexal structures of normal skin. Results: T-cadherin expression is restricted to basal keratinocytes of the epidermis. The basal cell layer of sebaceous glands was T-cadherin positive, whereas sebocytes were negative. Within apocrine glands, only myoepithelial cells were T-cadherin positive. In contrast, both the secretory coils and excretory ducts of eccrine glands were T-cadherin positive. In terminal hair follicles, the outer root sheath layers strongly expressed T-cadherin throughout different regions of the follicle, with the strongest immunoreactivity at the bulge and suprabulbar regions. T-cadherin and CK15 stem cell marker similarly localized within the bulge and suprabulbar region. T-cadherin and CD34 stem cell marker similarly localized at the suprabulbar level. Conclusion: The specific patterns of T-cadherin expression in the epidermis and adnexal structures suggest an important guardian role in skin homeostasis.","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":"63 1","pages":"68 - 78"},"PeriodicalIF":1.9,"publicationDate":"2016-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000451024","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65151483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

A Case of Syringolymphoid Hyperplasia with Follicular Mucinosis 淋巴淋巴样增生伴滤泡性黏液增多症1例

IF 1.9

Dermatopathology Pub Date : 2016-04-15 DOI: 10.1159/000445051

Emily L. Behrens, Christine E. Jabcuga, J. Gardner, S. Parker, D. Parker

引用次数: 0

Psammomatous Melanotic Schwannoma: A Challenging Histological Diagnosis 沙瘤性黑色素神经鞘瘤:一个具有挑战性的组织学诊断

IF 1.9

Dermatopathology Pub Date : 2015-12-15 DOI: 10.1159/000442708

Rastine Merat, Ildiko Szalay‐Quinodoz, E. Laffitte, G. Kaya

引用次数: 12

The Dilemma of Coexisting Nevoid Hyperkeratosis of the Nipple and Areola in Mycosis Fungoides: A Report of Three Cases 蕈样真菌病并发乳头乳晕空洞角化过度的困境:附3例报告

IF 1.9

Dermatopathology Pub Date : 2015-11-17 DOI: 10.1159/000441618

A. Polat Ekinci, Sule Ozturk Sari, N. Buyukbabani, C. Baykal

{"title":"The Dilemma of Coexisting Nevoid Hyperkeratosis of the Nipple and Areola in Mycosis Fungoides: A Report of Three Cases","authors":"A. Polat Ekinci, Sule Ozturk Sari, N. Buyukbabani, C. Baykal","doi":"10.1159/000441618","DOIUrl":"https://doi.org/10.1159/000441618","url":null,"abstract":"Nevoid hyperkeratosis of the nipple and areola (NHNA) is a rare clinicopathological entity showing persistent and strictly localized hyperkeratotic lesions of the nipple, areola or both with unknown etiopathogenesis. A similar clinical appearance may also be seen in different diseases with specific histopathological features. There are a few anecdotal reports on the association of NHNA with mycosis fungoides (MF), but they do not describe a uniform condition. In this report, we present 3 patients with hyperkeratotic lesions of the nipple and areola associated with MF but showing different histopathological features. We also review similar cases in the literature and discuss possibilities concerning this association. Two of our cases represent the association between MF and NHNA without histopathological features of MF on the nipple-areola complex. The other case represents hyperkeratosis of the nipple and areola with specific histological and immunohistochemical features of MF. Hence, we would like to hypothesize that MF may involve the nipple and areola and have an appearance similar to NHNA. Intriguingly, however, NHNA may occasionally also be seen in association with MF. However, this peculiar association requires further explanation.","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":"76 1","pages":"61 - 66"},"PeriodicalIF":1.9,"publicationDate":"2015-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000441618","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64944503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Benign Fibrous Histiocytomas of the Oral Mucosa: Report on Three Cases and Review of the Literature 口腔黏膜良性纤维组织细胞瘤3例报告并文献复习

IF 1.9

Dermatopathology Pub Date : 2015-04-29 DOI: 10.1159/000381618

Laure-Anne Prisse, P. Jayasooriya, B. R. Mendis, T. Lombardi

{"title":"Benign Fibrous Histiocytomas of the Oral Mucosa: Report on Three Cases and Review of the Literature","authors":"Laure-Anne Prisse, P. Jayasooriya, B. R. Mendis, T. Lombardi","doi":"10.1159/000381618","DOIUrl":"https://doi.org/10.1159/000381618","url":null,"abstract":"Benign fibrous histiocytomas (BFH) of the skin are common lesions, although they only rarely involve the oral mucosa. This article presents 3 additional cases of BFH of the oral mucosa, with a review of previously published cases. Although a malignant variant of BFH also exists, the present review focuses only on benign lesions. The clinical presentation, diagnosis, histopathological and immunohistochemical features of BFH are discussed. According to the present analysis, the majority of oral mucosal BFH have occurred in middle-aged and elderly patients, with a slight female predilection. Within the oral cavity, BHF may occur at any mucosal site, including the lips, tongue, buccal mucosa, mandibular and maxillary gingiva as well as the palate. Histopathology is essential to diagnose the lesion, while immunohistochemical investigations may be utilized to exclude the histopathological differential diagnoses such as juvenile xanthogranulomas and nevi. This review also revealed total excision as the treatment of choice for BFH, with a very good prognosis and an extremely low rate of relapse.","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":"2 1","pages":"52 - 60"},"PeriodicalIF":1.9,"publicationDate":"2015-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000381618","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64783890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Diagnostic Immunohistochemistry in Cutaneous Neoplasia: An Update 皮肤肿瘤的免疫组织化学诊断:最新进展

IF 1.9

Dermatopathology Pub Date : 2015-04-08 DOI: 10.1159/000377698

L. Compton, G. Murphy, C. Lian

{"title":"Diagnostic Immunohistochemistry in Cutaneous Neoplasia: An Update","authors":"L. Compton, G. Murphy, C. Lian","doi":"10.1159/000377698","DOIUrl":"https://doi.org/10.1159/000377698","url":null,"abstract":"Immunohistochemistry (IHC) is an important adjunct in the diagnosis of neoplastic skin diseases. In addition to the many established IHC markers currently in use, new markers continue to emerge, although their general acceptance and routine application requires robust validation. Here, we summarize the most well-established and commonly used biomarkers along with an array of newer ones reported in the past several decades that either demonstrate or hold high clinical promise in the field of cutaneous pathology. We also highlight recent applications of novel IHC markers in melanoma diagnosis including genetic mutation status markers [e.g. BRAF (v-raf murine sarcoma viral oncogene homolog B) and NRAS (neuroblastoma RAS viral oncogene homolog)] and an epigenetic alteration marker (e.g. 5-hydroxymethylcytosine). We specifically focus on the role of IHC in the differential diagnosis of cutaneous lesions that fall under the following categories: melanoma, epidermal tumors with an intraepidermal epitheliomatous pattern, spindle cell lesions of the dermis, small round blue cell tumors of the dermis, and cutaneous adnexal tumors. While IHC is a valuable tool in diagnostic dermatopathology, marker selection and interpretation must be highly informed by clinical context and the histologic differential diagnosis. With rapid progress in our understanding of the genetic and epigenetic mechanisms of tumorigenesis, new IHC markers will continue to emerge in the field of diagnostic dermatopathology.","PeriodicalId":42885,"journal":{"name":"Dermatopathology","volume":"2 1","pages":"15 - 42"},"PeriodicalIF":1.9,"publicationDate":"2015-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000377698","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64774532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 65