Balloon Cell Melanoma: Presentation of Four Cases with a Comprehensive Review of the Literature

IF 1.6 Q3 DERMATOLOGY
Gerardo Cazzato, E. Cascardi, A. Colagrande, A. Cimmino, G. Ingravallo, L. Lospalluti, P. Romita, A. Demarco, F. Arezzo, V. Loizzi, M. Dellino, Irma Trilli, E. Bellitti, P. Parente, T. Lettini, C. Foti, G. Cormio, E. Maiorano, L. Resta
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引用次数: 3

Abstract

Background: balloon cell melanoma represents less than 1% of all histological forms of malignant melanoma and represents a diagnostic challenge for the dermatopathologist. Methods: in this paper we present our cases of BCM found in our daily practice from 1 January 2008 to 31 December 2021, and we conduct a review of the literature relating to this entity in the period from the first description, 1970, to early 2022. Results: four cases of melanoma balloon cell have been extrapolated from our electronic database, while in the review of the literature we have identified 115 cases of patients with primary and/or metastatic BCM. Conclusions: we believe that future studies with numerous case series are essential not only to increase the knowledge of the pathophysiology of this neoplasm but also to correctly evaluate the response of BCM patients to new oncological therapies.
气球细胞黑色素瘤4例报告并文献综述
背景:气球细胞黑色素瘤在所有组织学形式的恶性黑色素瘤中所占比例不到1%,这对皮肤病理学家来说是一个诊断挑战。方法:在本文中,我们介绍了2008年1月1日至2021年12月31日在日常实践中发现的BCM病例,并对1970年第一次描述至2022年初期间与该实体相关的文献进行了综述。结果:从我们的电子数据库中推断出4例黑色素瘤气球细胞病例,而在文献综述中,我们确定了115例原发性和/或转移性BCM患者。结论:我们相信,未来的大量病例系列研究不仅对增加对该肿瘤病理生理学的了解,而且对正确评估BCM患者对新肿瘤学疗法的反应至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Dermatopathology
Dermatopathology DERMATOLOGY-
自引率
5.30%
发文量
39
审稿时长
11 weeks
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