Anthony Kanbar, Charbel Dabal, Joey El Khoury, Rami Halabi, Serge Assaf, Anthony Mina, Sabine Breidi, Maher Abdessater, Raghid El Khoury
{"title":"Diagnosis and Management of Polyorchidism: A Case Report and Literature Review.","authors":"Anthony Kanbar, Charbel Dabal, Joey El Khoury, Rami Halabi, Serge Assaf, Anthony Mina, Sabine Breidi, Maher Abdessater, Raghid El Khoury","doi":"10.1155/2023/1620276","DOIUrl":"https://doi.org/10.1155/2023/1620276","url":null,"abstract":"<p><p>Polyorchidism, or supernumerary testis, is a rare congenital abnormality of the genitourinary system. In this paper, we present the case of triorchidism in a seven-year-old asymptomatic child with a suspect left scrotal mass detected on routine physical examination. Imaging studies revealed a third testicle in the left hemiscrotum, with comparable dimensions, signal intensity on MRI, and Doppler flow on ultrasound with the ipsilateral testis. We also discuss the clinical presentations, classifications, and current diagnostic and therapeutic strategies of this condition.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9748515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anthony Guglin, Robert Weiss, Adityabikram Singh, Anugya Mittal, Thomas Hwang, Ankit Shah
{"title":"Concurrent Xanthogranulomatous Pyelonephritis and Upper Urinary Tract Transitional Cell Carcinoma.","authors":"Anthony Guglin, Robert Weiss, Adityabikram Singh, Anugya Mittal, Thomas Hwang, Ankit Shah","doi":"10.1155/2023/6021178","DOIUrl":"https://doi.org/10.1155/2023/6021178","url":null,"abstract":"<p><p>A 37-year-old male with a history of chronic nephrolithiasis presented to the ED with gross hematuria, clot retention, and right flank pain. The patient had radiological findings of perinephric stranding, marked hydronephrosis, and marked thinning of the right renal parenchyma on computed tomography (CT), all suggestive of xanthogranulomatous pyelonephritis (XGP). The specimen following radical nephrectomy revealed urothelial carcinoma (UC) in a background of XGP but with no evidence of spread to regional lymph nodes. Follow-up imaging revealed hypodense lesions in the liver which demonstrated UC on biopsy. This is the first reported case of a young patient presenting with such an advanced stage of UC in the setting of XGP. It illustrates the link between inflammatory processes of the kidney and malignancy of the upper urinary tract.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9267202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brecht Devos, Hendrik Vandeursen, Olivier d'Archambeau, Eric Vergauwe
{"title":"Renal Pseudoaneurysm with Associated Arteriovenous Fistula as a Cause of Delayed Bleeding after Percutaneous Nephrolithotomy: A Case Report and Current Literature Review.","authors":"Brecht Devos, Hendrik Vandeursen, Olivier d'Archambeau, Eric Vergauwe","doi":"10.1155/2023/5103854","DOIUrl":"https://doi.org/10.1155/2023/5103854","url":null,"abstract":"<p><strong>Background: </strong>Pseudoaneurysm (PA) with associated arteriovenous fistula (AVF) is a rare delayed bleeding complication, occurring in less than 1% of patients after percutaneous nephrolithotomy (PNL). <i>Case presentation</i>. A 54-year-old man underwent PNL on February 28, 2023, for a large renal calculus in the right kidney lower pole, with postoperative delayed bleeding: macroscopic hematuria and bladder clot retention after 3 weeks. An iatrogenic PA and AVF were diagnosed after the failure of conservative measures. The patient was successfully treated with superselective angioembolization (SAE) under local anesthesia.</p><p><strong>Conclusion: </strong>Late hemorrhagic complications after PNL can be severe. Rapid identification of a renal PA and AVF with SAE has a high success rate and low complication rate, avoiding prolonged hospitalization time and major renal surgery for this patient.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393521/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9933263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response of Patients with Taxane-Refractory Advanced Urothelial Cancer to Enfortumab Vedotin, a Microtubule-Disrupting Agent.","authors":"Makito Miyake, Nobutaka Nishimura, Tatsuki Miyamoto, Takuto Shimizu, Kenta Ohnishi, Shunta Hori, Yosuke Morizawa, Daisuke Gotoh, Yasushi Nakai, Kazumasa Torimoto, Tomomi Fujii, Kiyohide Fujimoto","doi":"10.1155/2023/1024239","DOIUrl":"https://doi.org/10.1155/2023/1024239","url":null,"abstract":"<p><p>Enfortumab vedotin (EV), a nectin-4-directed antibody conjugated to monomethyl auristatin E (MMAE), has been approved for patients with advanced urothelial carcinoma (aUC) previously treated with platinum-based chemotherapy and immune inhibitors. Taxane agents and MMAE share antitumor mechanisms through microtubule disruption, thus raising a notable concern regarding cross-resistance between these drugs. This case report describes two patients with taxane-based chemotherapy-refractory aUC who responded well to EV. A 71-year-old man (case 1) with pT3N0M0 renal pelvic UC showed a partial response to EV in metastatic lesions of the bilateral lungs and right pelvic lymph nodes after three cycles of paclitaxel plus gemcitabine chemotherapy. A 53-year-old man (case 2) with cT3bN2M0 bladder UC underwent platinum-based neoadjuvant chemotherapy and the following radial cystectomy (ypTis ypN0). He developed bilateral lung metastases and showed a complete response to EV in the metastatic lesions after 20 cycles of paclitaxel plus nedaplatin chemotherapy. Our experience of two cases demonstrated that tumor response to EV can be expected in patients with taxane-refractory aUC.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10667420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Case Reports in UrologyPub Date : 2022-11-21eCollection Date: 2022-01-01DOI: 10.1155/2022/3817554
Hugo Otaola-Arca, Patricio Vargas, Daniel Hasson, Marcelo Orvieto, Carmen Niño-Taravilla, Hugo Bermúdez
{"title":"Intranodal Ultrasound-Guided Percutaneous Methylene Blue Injection for the Identification of Leakage Point during Laparoscopic Repair of Refractory Chylous Ascites after Laparoscopic Lymphadenectomy for Kidney Cancer.","authors":"Hugo Otaola-Arca, Patricio Vargas, Daniel Hasson, Marcelo Orvieto, Carmen Niño-Taravilla, Hugo Bermúdez","doi":"10.1155/2022/3817554","DOIUrl":"https://doi.org/10.1155/2022/3817554","url":null,"abstract":"<p><p>Chylous ascites is an uncommon complication after surgery that can result in malnutrition and immunodeficiency. Therefore, surgical interventions are reserved for refractory patients, and the primary success factor for these interventions is locating the point of leakage, which is often tricky. We describe a case of a 56-year-old male with chylous ascites after laparoscopic radical nephrectomy and lumbo-aortic lymphadenectomy for kidney cancer. The patient was initially managed with dietary modifications and drainage placement. Afterward, lymphography with Lipiodol, percutaneous embolization of the leakage point, and total parenteral nutrition were established. Finally, the patient underwent laparoscopic repair after identifying the leakage point by injecting methylene blue through an inguinal node. Complete resolution was achieved, and no complications related to the procedure were recorded. Intranodal methylene blue injection can be an invaluable tool to identify the point of leakage in selected patients to improve the outcomes of surgical repair of refractory chylous ascites.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705082/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40711978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Case Reports in UrologyPub Date : 2022-11-17eCollection Date: 2022-01-01DOI: 10.1155/2022/9176199
David Zekan, Kareem Wasef, Zachary Werner, Robert Grammer, Cara Lombard, Adam Luchey, Ali Hajiran
{"title":"Crisis Averted: Clinical T1b Renal Mass with Concurrent Arteriovenous Malformation and Renal Vein Thrombus.","authors":"David Zekan, Kareem Wasef, Zachary Werner, Robert Grammer, Cara Lombard, Adam Luchey, Ali Hajiran","doi":"10.1155/2022/9176199","DOIUrl":"https://doi.org/10.1155/2022/9176199","url":null,"abstract":"<p><p>Arteriovenous malformations (AVMs) secondary to renal-cell carcinoma (RCC) are well-described in the literature. Independently, renal vein and inferior vena cava tumor thrombi can be detected in locally-advanced RCC. A 67-year-old gentleman presented with a cT1b renal mass detected on workup for elevated creatinine. Multiphase CT imaging obtained for partial nephrectomy surgical-planning revealed an initially-missed renal cortical AVM. This drastically changed the plan for intervention, including use of an open approach with AVM embolization by interventional radiology prior and avoidance of a nephron-sparing approach. Final pathology confirmed the AVM and a subclinical renal vein thrombus masked by arterial flow on CT imaging, making this the first concurrent case described in the literature. Herein, we describe avoidance of catastrophic intraoperative hemorrhage by careful review of preoperative imaging and provide a literature review of imaging modalities for both renal surgical-planning and detection of tumor thrombi in RCC.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40709369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Case Reports in UrologyPub Date : 2022-10-04eCollection Date: 2022-01-01DOI: 10.1155/2022/9966553
Victor A Abdullatif, Jacob Novack, Philip J Shalhoub, Todd G Campbell, Joel E Abbott
{"title":"A Rare Case of a Bladder Neck Abscess Masquerading as a Benign Mass.","authors":"Victor A Abdullatif, Jacob Novack, Philip J Shalhoub, Todd G Campbell, Joel E Abbott","doi":"10.1155/2022/9966553","DOIUrl":"https://doi.org/10.1155/2022/9966553","url":null,"abstract":"<p><strong>Introduction: </strong>Bladder neck abscesses are rare urologic pathologies with very few cases published in modern literature. This report explores a case of a bladder neck mass incidentally found on computed tomography (CT) imaging in a patient with an iliopsoas abscess. <i>Case Presentation.</i> We present a case of a 60-year-old woman who was recently treated for sepsis secondary to an iliopsoas abscess in July of 2022. A CT scan revealed an indeterminate structure in the posterior inferior left paramedian bladder wall. During a cystoscopy with transurethral resection of the mass, an abscess was uncovered and evacuated. A postoperative Foley catheter was left in place, and the patient recovered without any complications.</p><p><strong>Conclusion: </strong>At the time of publication, the patient feels well and denies pain or lower urinary tract symptoms. Although bladder abscesses are exceptionally rare, incidental findings during cystoscopy may warrant further investigation in patients with comorbid abscesses.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553506/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33513954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Plasmacytoid Urothelial Carcinoma of the Bladder That Manifests Disseminated Carcinomatosis of the Bone Marrow: A Case Report of Extremely Rapid Progression.","authors":"Nobuhiko Shimizu, Yoshinobu Moritoki, Nao Katsumi, Takahiro Yanase, Teruaki Sugino, Kazuhiro Kanemoto, Hidetoshi Akita, Takahiro Yasui","doi":"10.1155/2022/6082700","DOIUrl":"https://doi.org/10.1155/2022/6082700","url":null,"abstract":"<p><p>Plasmacytoid urothelial carcinoma (PUC) of the bladder is a rare variant of invasive urothelial carcinoma (UC) with aggressive behavior. Despite its prognosis being poorer than that of conventional UC, a median overall survival of approximately 2 years is ensured when it is treated with radical cystectomy (RC), and few patients die within a few months of RC. In this paper, we report the case of a patient with PUC who developed widespread bone metastasis only 6 weeks after RC, which resulted in death within 2 months postoperatively.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33482434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Case Reports in UrologyPub Date : 2022-08-27eCollection Date: 2022-01-01DOI: 10.1155/2022/4835945
Rojan Adhikari, Hari Prasad Baral, Utsav Bhattarai, Ravi Kiran Gautam, Kiran Jung Kunwar, Dipesh Shrestha, Bijay Mansingh Katwal
{"title":"A Rare Case Report of Giant Urinary Bladder Stone Causing Recurrent Dysuria in a Woman.","authors":"Rojan Adhikari, Hari Prasad Baral, Utsav Bhattarai, Ravi Kiran Gautam, Kiran Jung Kunwar, Dipesh Shrestha, Bijay Mansingh Katwal","doi":"10.1155/2022/4835945","DOIUrl":"https://doi.org/10.1155/2022/4835945","url":null,"abstract":"<p><strong>Background: </strong>Large urinary bladder stones are not common and even less common in females. We report a case of large bladder stone presented with acute retention of urine in a female patient. <i>Case Report</i>. A 62-year-old female presented in emergency department with retention of urine for 12 hours with history of recurrent UTIs for last 1 year. She was also complaining of mild dull lower abdominal pain for last 6 months. She had no history of incontinence of urine and fever. On physical examination, hard mass was palpable on suprapubic region on palpation of abdomen. Urine culture shows Escherichia coli for which antibiotics was given. An X-ray kidney ureter bladder showed a radio-opacity in the pelvic region measuring 9 × 8 cm in size. Ultrasonography revealed bilateral mild hydronephrosis with a large bladder stone. Open cystolithotomy was performed, and the stone was taken out. Stone biochemical analysis showed predominantly urate crystals. Patient had uneventful postoperative course, and she was discharged on 4<sup>th</sup> postoperative day and was followed up for 1 months after operation.</p><p><strong>Conclusions: </strong>Large urinary bladder stones are not common and even less common in females. Clinician should have think regarding large bladder stone as a cause of recurrent lower urinary tract symptoms like dysuria and should assess renal function for proper treatment. Open cystolithotomy is choice of operation in large bladder stone.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40352283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Case Reports in UrologyPub Date : 2022-08-22eCollection Date: 2022-01-01DOI: 10.1155/2022/4466602
Agustín Fraile Poblador, Manuel Hevia Palacios, Manuel Rodríguez Vegas, Alberto Artiles Medina, Enrique Sanz Mayayo, Silvia García Barreras, Guillermo Fernández Conejo, Rafael Rodríguez Patrón, Varona Crespo Constatino, Ana Saiz González, Javier Burgos Revilla
{"title":"Male Perineal Carcinoma: Experience in 4 Cases and Literature Review.","authors":"Agustín Fraile Poblador, Manuel Hevia Palacios, Manuel Rodríguez Vegas, Alberto Artiles Medina, Enrique Sanz Mayayo, Silvia García Barreras, Guillermo Fernández Conejo, Rafael Rodríguez Patrón, Varona Crespo Constatino, Ana Saiz González, Javier Burgos Revilla","doi":"10.1155/2022/4466602","DOIUrl":"https://doi.org/10.1155/2022/4466602","url":null,"abstract":"<p><p>Perineal carcinoma of unknown origin is a rare and aggressive disease, so an early diagnosis and adequate treatment are essential to prevent its progression. We report the first series of cases of perineal carcinoma of unknown origin: (I) a 62-year-old male patient being followed up for a urethral stricture treated with periodic dilations with subsequent development of perineal abscesses and perineal carcinoma; (II) a 67-year-old male patient who consults for urinary discomfort associated with a perineal abscess. Recurrence of the abscess in the first month revealed the presence of an underlying perineal carcinoma; (III) a 78-year-old male patient that underwent urethroplasty with graft with subsequent regimen of periodical dilations. Recurrent formation of perianal abscesses revealed the presence of an underlying perineal carcinoma; and (IV) a 78-year-old male patient with history of in situ penile carcinoma treated by glans resurfacing. He consulted for penile pain, and imaging tests revealed a perineal abscess adjacent to the left corpus cavernosum. The core needle biopsy revealed a squamous cell carcinoma. Penile exploration and negative glans biopsy ruled out possible recurrence of penile carcinoma. The form of presentation of the disease has been very similar in all patients, demonstrating the presence of perineal abscess in all cases. Two patients had inguinal lymph node disease at diagnosis. All patients were treated by surgery, and three of them required adjuvant systemic treatment. Surgery combined with systemic treatment is probably the best option if the patient's conditions allow it.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40336015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}