Case Reports in Urology最新文献

{"title":"Correction to \"Systemic Sporotrichosis With Testicular Involvement: Literature Review and Case Report\".","authors":"","doi":"10.1155/criu/9840325","DOIUrl":"10.1155/criu/9840325","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1155/criu/4235866.].</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"9840325"},"PeriodicalIF":0.0,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13396430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pembrolizumab-Induced Morphea in a Patient With Metastatic Urothelial Carcinoma.","authors":"Matthew A Drescher, Douglas W Murray, Douglas J Grider","doi":"10.1155/criu/2930700","DOIUrl":"10.1155/criu/2930700","url":null,"abstract":"<p><strong>Introduction: </strong>Immune checkpoint inhibitors, such as pembrolizumab, are increasingly used in high-grade urothelial carcinomas. Immune checkpoint inhibitors are known to cause immune-related adverse events (irAEs), often involving the skin.</p><p><strong>Case presentation: </strong>Reported is a 59-year-old woman with metastatic high-grade urothelial carcinoma of the right renal pelvis previously treated with chemoradiation and surgery. She developed morphea 1.5 years after initiating pembrolizumab therapy. The patient presented with violaceous, indurated plaques and paresthesias of the lower extremities. Biopsies revealed thickened collagen bundles and perivascular inflammation. MRI excluded eosinophilic fasciitis. She was diagnosed with pembrolizumab-induced morphea and treated with methotrexate and topical corticosteroids, leading to partial improvement.</p><p><strong>Conclusion: </strong>As immunotherapy becomes more widely used in urologic oncology, recognition of rare cutaneous irAEs such as morphea is crucial for timely diagnosis and management.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"2930700"},"PeriodicalIF":0.0,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13392509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148580080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invasive Primary Melanoma of the Kidney: A Rare Presentation of an Uncommon Malignancy and Review of Literature.","authors":"Joshua Ghoulian, Jersey-Kate Castillo, Ronaldo Dario Gnass, Vicente Ramos-Santillan, Antoin Douglawi, David Caba, Muhannad Alsyouf","doi":"10.1155/criu/3596493","DOIUrl":"10.1155/criu/3596493","url":null,"abstract":"<p><p>Primary melanoma is a very rare malignancy arising from the kidney. We present a case of a 78-year-old female who presented with locally advanced primary kidney melanoma requiring complex surgical intervention and multidisciplinary management. The patient underwent an open left radical nephrectomy with distal pancreatectomy, splenectomy, and colonic resection, followed by adjuvant immunotherapy. We additionally review the literature regarding the diagnosis and management of primary renal melanoma.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"3596493"},"PeriodicalIF":0.0,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13390015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148562862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep Cavernosal Melanoma Without Clinically Evident Mucosal or Cutaneous Involvement: A Case Report.","authors":"M J Iglesias, M Bogliaccini, L Mouro, C Villa","doi":"10.1155/criu/4792867","DOIUrl":"10.1155/criu/4792867","url":null,"abstract":"<p><strong>Background: </strong>Penile melanoma is an extremely rare malignancy, representing less than 0.1% of all melanomas. It most commonly arises from the glans, foreskin, or urethral meatus. Deep cavernosal involvement without clinically evident cutaneous, mucosal, or urethral disease is an unusual presentation and poses significant diagnostic and therapeutic challenges.</p><p><strong>Case presentation: </strong>A 23-year-old male presented with progressive penile induration and pain. MRI revealed a lesion predominantly involving the corpus cavernosum, with no clinically evident cutaneous, mucosal, or urethral involvement. An excisional biopsy established the diagnosis of malignant melanoma; however, the initial specimen showed tumor involvement of the resection margin and did not include epidermal sampling. Systemic staging with whole-body CT and PET-CT showed no evidence of metastatic disease. The patient subsequently underwent partial penectomy with bilateral sentinel lymph node dissection, showing negative sentinel lymph nodes and free final surgical margins. One year later, 18F-FDG PET-CT demonstrated nodal and osseous metastatic disease, with hypermetabolic lymphadenopathies in the distal retroperitoneal, left iliac, and left inguinal regions, osseous lesions in the sternal manubrium, and a new right upper-lobe pulmonary micronodule. The patient received immunotherapy with a limited clinical response.</p><p><strong>Conclusion: </strong>This case describes an unusual presentation of melanoma predominantly involving the corpus cavernosum without clinically evident cutaneous, mucosal, or urethral involvement. The absence of epidermal sampling prevents definitive histological exclusion of a regressed or deeply invasive mucosal/cutaneous primary lesion. This report highlights the aggressive behavior of deeply located penile melanoma and the need for careful clinicopathological correlation and individualized multidisciplinary management.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"4792867"},"PeriodicalIF":0.0,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13392520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148580431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Treatment of Glans Tumescence Dysfunction Caused by Abnormal Venous Communication Between the Great Saphenous Vein and the Deep Dorsal Vein: A Case Report.","authors":"Alessandro Zucchi, Fabio Pezzoni, Filippo Dazzi, Matteo Pacini, Antonio Luigi Pastore, Manfredi Sequi, Fabio Maria Valenzi, Fabrizio Ildefonso Scroppo","doi":"10.1155/criu/6933520","DOIUrl":"10.1155/criu/6933520","url":null,"abstract":"<p><strong>Background: </strong>Penile venous abnormalities are an uncommon cause of erectile dysfunction and are rarely implicated in isolated glans tumescence impairment. We report what may be the first successful surgical treatment of glandular tumescence dysfunction caused by an anomalous venous communication between the deep dorsal vein of the penis and the left great saphenous vein.</p><p><strong>Case presentation: </strong>A 42-year-old man presented with lifelong inadequate glans tumescence and mild erectile maintenance difficulty (International Index of Erectile Function-5 score, 18). Physical examination and hormonal evaluation were unremarkable. Dynamic penile color Doppler ultrasonography after intracavernosal prostaglandin E1 demonstrated normal cavernosal arterial inflow and preserved cavernous veno-occlusive function but showed markedly increased flow in the deep dorsal vein despite rigid shaft erection and persistent poor glans engorgement. Dynamic cavernosography identified an isolated anomalous collateral vessel connecting the deep dorsal vein to the left great saphenous vein, with no additional venous leakage sites. Surgical correction consisted of ligation and excision of the anomalous collateral vein, excision of the deep dorsal vein through an anterograde penile skin degloving approach, and selective ligation of cavernous veins.</p><p><strong>Conclusions: </strong>The patient reported complete restoration of glans tumescence at 1 month, sustained at 1 year, with improvement of the International Index of Erectile Function-5 score from 18 to 23. This case highlights the diagnostic value of cavernosography in selected patients with discordant findings between shaft rigidity and glans engorgement and suggests that targeted surgical correction may be effective when a highly localized venous shunt is identified.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"6933520"},"PeriodicalIF":0.0,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13376849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148580076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare Early Coexistence of Classic Urothelial and Small Cell Carcinoma of the Urinary Bladder.","authors":"Mohannad N AbuHaweeleh, Amro Elfaieg, Abdelkareem Alhyari, Nada Abuhayeh, Ibrahim A Khalil, Nabil Mahmood, Mohammed Akhtar, Khalid Al-Rumaihi","doi":"10.1155/criu/2064505","DOIUrl":"10.1155/criu/2064505","url":null,"abstract":"<p><strong>Introduction: </strong>Small cell carcinoma of the bladder (SCCB) is a rare aggressive cancer, representing less than 1% of bladder cancers. Similar to small cell lung cancer (SCLC), it progresses rapidly, metastasizes early, and has a poor prognosis, complicating treatment. Unlike more common bladder cancers, SCCB often resists localized treatments and responds better to chemotherapy. However, its management generally relies on protocols for SCLC due to limited specific research.</p><p><strong>Case presentation: </strong>A 47-year-old male from Bangladesh presented with intermittent painless hematuria, weak urinary stream, and incomplete voiding for 2 months. His medical history includes diabetes mellitus, chronic kidney disease, hypothyroidism, adrenal adenoma, and coronary artery disease. His physical examination was unremarkable. His blood work up showed hypochromic microcytic anemia and elevated creatinine. Urine cytology revealed atypical degenerated urothelial cells, polymorphonuclear leukocytes, and red blood cells. He underwent flexible cystoscopy, which showed a nodular tumor with a wide base at the left lateral bladder wall measuring less than 3 cm. He had a CT scan, which revealed irregular thickening in the left posterolateral bladder wall, suggesting muscle-invasive carcinoma extending into the perivesical fat. He had an MRI scan which confirmed a 4 x 4.5 - cm mass with extravesical involvement. Histopathology examination from his transurethral resection of bladder tumor specimens showed mixed carcinoma, comprising both classic invasive urothelial carcinoma (UC) and SCCB. The small cell component exhibited scant cytoplasm, high nuclear-to-cytoplasmic ratio, hyperchromatic nuclei, and numerous mitotic figures, with synaptophysin and weak chromogranin positivity; UC cells were GATA-3 positive. Surgical resection removed most of the tumor. The patient tolerated the procedure well, with no complications. After four chemotherapy cycles, he had a follow-up PET CT, which showed significant tumor regression.</p><p><strong>Conclusion: </strong>This case highlights the unusual early coexistence of SCCB with classic UC in the bladder, emphasizing the importance of comprehensive histopathological and immunohistochemical evaluation for accurate diagnosis and treatment planning. Further research on SCCB could improve diagnosis, treatment strategies, and identification of molecular targets, potentially enhancing survival rates and patient quality of life.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"2064505"},"PeriodicalIF":0.0,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13332126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148391892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidentally Detected Bilobed Testis in an Asymptomatic Adult Male: An Uncommon Variant of Polyorchidism.","authors":"Rachel Cockburn, Jennifer Xu, Anthony Kiosoglous","doi":"10.1155/criu/9963636","DOIUrl":"10.1155/criu/9963636","url":null,"abstract":"<p><p>Bilobed testis is an extremely rare congenital anomaly considered an incomplete form of polyorchidism, resulting from incomplete division of the genital ridge during embryogenesis. Fewer than 250 cases of polyorchidism have been reported worldwide, and bilobed variants represent only a small proportion of these cases. Recognition of this benign anatomical variant is important to avoid unnecessary surgical intervention. We report the case of a 37-year-old asymptomatic male in whom a left scrotal mass was detected incidentally on clinical examination. Scrotal ultrasonography demonstrated a well-defined ovoid nodule adjacent to the posterior-inferior aspect of the left testis measuring 14 × 15 × 8 mm. The lesion demonstrated identical echogenicity and internal architecture to the adjacent testicular parenchyma, consistent with a bilobed testis. Follow-up ultrasonography at 18 months showed no interval change, confirming stability. Given the benign imaging features, absence of symptoms and stability on serial imaging, the patient was managed conservatively with reassurance and education regarding testicular self-examination. This case highlights the importance of recognising bilobed testis as a rare but benign congenital variant. Accurate radiological diagnosis can prevent unnecessary surgical exploration, reduce patient anxiety and preserve fertility.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"9963636"},"PeriodicalIF":0.0,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13312304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148353784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urologic Involvement in the Management of Ureteral Hernias: A Case Series.","authors":"Sajya M Singh, Maya Weerasooriya, Joseph Baiocco, Kendrick Campbell, Tova Weiss, Gregory P Murphy","doi":"10.1155/criu/9002319","DOIUrl":"10.1155/criu/9002319","url":null,"abstract":"<p><p>In this case series, we describe our approach to the urologic management of ureteral hernias. This is a single-institution, multi-surgeon cohort of patients who presented with an abdominal hernia involving a ureter between 2018 and 2025. Among eight patients, seven male patients (87%) had an inguinal hernia involving the ureter. Six patients underwent urologic intervention at the time of inguinal hernia repair, most commonly preoperative ureteral stent placement (40%). Three patients (50%) experienced inguinal ureteral hernia recurrence, of whom two underwent ureteral reimplantation. Based on our experience, the majority of inguinal ureteral hernias can be managed with a preoperative ureteral stent at the time of hernia repair, although more complex ureteral reconstruction may be required in the setting of recurrence.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"9002319"},"PeriodicalIF":0.0,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13285589/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148309821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single Epididymis Metastasis 12 Years After Radical Prostatectomy: A Case Report and Literature Review.","authors":"Antonio Fanelli, Francesco Troiano, Francesco Guzzi, Marco Finati, Anna Ricapito, Oscar Selvaggio, Ugo Falagario, Gian Maria Busetto, Luigi Cormio, Carlo Bettocchi, Giuseppe Carrieri","doi":"10.1155/criu/7984631","DOIUrl":"10.1155/criu/7984631","url":null,"abstract":"<p><strong>Introduction: </strong>Metastatic spread of prostate cancer to the epididymis is exceptionally rare. Recognition is challenging because clinical and ultrasonographic findings may mimic benign or primary paratesticular lesions.</p><p><strong>Case presentation: </strong>We describe a 71-year-old man who developed an isolated epididymal metastasis 12 years after radical prostatectomy for high-risk prostate cancer. After adjuvant treatment and later biochemical recurrence managed with salvage radiotherapy and androgen deprivation therapy, prostate-specific antigen rose to 2.2 ng/mL despite castrate testosterone levels. Choline positron emission tomography/computed tomography identified a suspicious paratesticular lesion. Scrotal ultrasound showed a cystic mass initially suggestive of a benign epididymal lesion. Surgical exploration with hydrocelectomy and excision of the epididymal mass was performed for both diagnostic and therapeutic purposes. Histology and immunohistochemistry confirmed metastatic adenocarcinoma of prostatic origin. After surgery, prostate-specific antigen became undetectable.</p><p><strong>Conclusion: </strong>This case underlines the need to consider epididymal metastasis during follow-up when prostate-specific antigen rises without typical sites of relapse and supports the role of dedicated scrotal evaluation, molecular imaging, and individualized surgical management in selected patients.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"7984631"},"PeriodicalIF":0.0,"publicationDate":"2026-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13261093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148253701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Delayed Repair of a Penile Fracture due to COVID-19 Infection.","authors":"Darren William Rodgers, Keith Pace","doi":"10.1155/criu/9751872","DOIUrl":"10.1155/criu/9751872","url":null,"abstract":"<p><strong>Background: </strong>Penile fracture is a rare condition characterised by disruption of the tunica albuginea typically caused by blunt trauma to a tumescent penis. It is a urological emergency that requires prompt diagnosis with a view to urgent treatment. The current global consensus on management of penile fractures is urgent surgical exploration and repair of the tunical defect. This is recommended with a view to minimise the risk of long-term functional outcomes, mostly relating to sexual dysfunction. However, the lack of high quality data on 'immediate' versus 'delayed' surgical repair groups in terms of long-term outcomes means that the exact timing of surgical repair is still debatable.</p><p><strong>Case presentation: </strong>A 50-year-old healthy sexually active male presented after a snapping sound during sexual intercourse 90 minutes before, followed by detumescence and penile pain. A tunical breach in the left proximal penile shaft was diagnosed clinically and confirmed on emergency ultrasound. The patient tested positive for COVID-19 and, given the perioperative risk of morbidity and mortality, it was decided to delay surgical repair. 10 days after the injury, following a negative COVID-19 test, he successfully underwent circumferential degloving, circumcision and closure of the tunical defect. Upon review at 4 and 20 months post-op, there was no scarring or penile curvature, and he was having normal painless erections and penetrative sexual intercourse.</p><p><strong>Conclusions: </strong>This is a case of early presentation of penile fracture in a healthy sexually active male, where surgical repair was delayed by 10 days because of COVID-19 infection, with positive short and medium term outcomes. It reinforces the idea that penile fracture patients who present late should still be offered surgery and that delaying surgery to optimise a patient's condition may be an acceptable approach. However, more research is needed into timing of surgical repair and its effect on long-term functional outcomes.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"9751872"},"PeriodicalIF":0.0,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13248109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148219965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}