Case Reports in Urology最新文献

{"title":"Calculi in Three of the Four Ureters in a Case of Bilateral Complete Duplication, Complicated by Pyonephrosis in One Obstructed Moiety-A Rare Case Report.","authors":"Swanand E Chaudhary, Ved Mahajan, Ritvij Patankar, Rohit Nimje","doi":"10.1155/criu/6380877","DOIUrl":"10.1155/criu/6380877","url":null,"abstract":"<p><p>Duplex ureters, a urinary tract anomaly affecting 0.8% of the population, are typically asymptomatic. This case report describes an exceptionally rare presentation of bilateral complete ureteral duplication with calculi in three out of four ureters and pyonephrosis in one obstructed renal moiety. Although most cases of ureteral duplication are incidental findings, this report highlights a rare instance where bilateral complete duplication presented with symptomatic complications requiring intervention.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"6380877"},"PeriodicalIF":0.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13084322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147723862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clear Cell Renal Cell Carcinoma: Rare and Atypical Metastatic Localizations-A Case Series.","authors":"Roosvelt Tessa Djambong, Bril Laurel Follah Feudjio, Stéphane Rysselinck, Emmanuel Seront, Günter Niegisch, Christina Neppl, Alexander Müller","doi":"10.1155/criu/1777980","DOIUrl":"10.1155/criu/1777980","url":null,"abstract":"<p><strong>Introduction: </strong>Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of kidney cancer, characterized by its high degree of vascularity and metastatic potential. Although common metastatic sites include the lungs, lymph nodes, bones, liver, adrenal glands, and brain, rare localizations, such as those observed in the pancreas, gallbladder, thyroid gland, and nasal cavities, pose significant diagnostic and therapeutic challenges.</p><p><strong>Case presentation: </strong>The following report details four cases of ccRCC with atypical metastatic localizations: A nasal metastasis in one patient, a thyroid metastasis in one patient, a gallbladder metastasis in one patient, and pancreatic localizations in all four patients. These metastases, frequently asymptomatic, contributed to delays in diagnosis. The therapeutic management of these cases was individualized, incorporating surveillance, surgical intervention, radiotherapy, or immunotherapy, depending on the patient's clinical profile and the progression of the lesions.</p><p><strong>Conclusion: </strong>This series illustrates the diversity of metastatic presentations of ccRCC and highlights the importance of prolonged, personalized follow-up after nephrectomy. A multidisciplinary approach remains essential for the timely detection and optimal management of rare metastatic sites.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"1777980"},"PeriodicalIF":0.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13084330/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Testicular Compartment Syndrome Post Bilateral Microdissection Testicular Sperm Extraction: A Case Report and Review of the Current Literature.","authors":"Catherine Larard, Katie McComb, Ivo Donkov, Alberto Coscione, Panagiotis Nikolinakos, Karl H Pang","doi":"10.1155/criu/2710616","DOIUrl":"10.1155/criu/2710616","url":null,"abstract":"<p><strong>Background: </strong>Testicular compartment syndrome (TCS) is a rare phenomenon with around 14 cases reported in the literature. It occurs when extraluminal compression or increased venous resistance leads to raised intratesticular pressure. The fibrous tunica albuginea covering the testes does not distend, meaning the pressure is not relieved and compartment syndrome can develop. The ensuing reduction in perfusion and subsequent reperfusion injury can compromise testicular viability, making prompt identification and early surgical intervention essential in optimising outcomes.</p><p><strong>Case presentation: </strong>A 41-year-old male presented to the emergency department with acute severe bilateral testicular pain 1 day after bilateral microdissection testicular sperm extraction (mTESE) for primary infertility and azoospermia. He reported a gradual onset of bilateral testicular pain throughout the day accompanied by oozing and bleeding from the surgical wound. The pain escalated with time, and both testicles were exquisitely tender on palpation. Ultrasonography (US) demonstrated diffuse scrotal sac thickening, heterogenous testicles with hyperaemia on Doppler flow and bilateral hyperaemic enlargement of both epididymi. Thus, an emergency scrotal exploration was performed with evacuation of a left intratesticular haematoma and a right peritesticular haematoma. This restored perfusion to both testes and the patient had an uneventful postoperative course. A follow-up US after 6 weeks revealed both testicles had a reduction in volume and reduced blood flow.</p><p><strong>Conclusion: </strong>TCS is a previously undocumented complication of mTESE that should be considered in any patient presenting with pain out of proportion to clinical findings. Although the diagnosis is primarily clinical, US features, such as initial hyperaemia progressing to reduced blood flow, can support the diagnosis. Early surgical intervention to decompress the testis by incising the tunica layers is critical to reduce intratesticular pressure, restore perfusion and preserve testicular viability.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"2710616"},"PeriodicalIF":0.0,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunotherapy-Related Cystitis Induced by Nivolumab for Advanced Gastric Cancer: A Case Report.","authors":"Kentaro Arinami, Kozue Ito, Go Hasegawa, Yurie Takizawa, Yohei Ikeda, Takeshi Suda, Noboru Hara, Tsutomu Nishiyama","doi":"10.1155/criu/4082092","DOIUrl":"10.1155/criu/4082092","url":null,"abstract":"<p><p>A 70-year-old man received treatment for advanced gastric cancer involving capecitabine, oxaliplatin, and nivolumab therapy. Following four courses of this treatment, he developed severe urethralgia and hematopyuria. Urine bacterial culture was negative. Cystoscopy revealed readily bleeding and edematous, reddish mucosa. Computed tomography identified edematous changes in the wall of the bladder, but no lesions were noted in the upper urinary tract. The bladder wall was biopsied, and pathological findings indicated erosion and hemorrhage of the bladder mucosa, accompanied by lymphocytic infiltration. Based on the overall clinical presentation, immunotherapy-associated cystitis induced by nivolumab treatment for advanced gastric cancer was suspected. He began taking prednisolone at a dosage of 25 mg per day, which was gradually tapered over time, and the urinary symptoms markedly improved.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"4082092"},"PeriodicalIF":0.0,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arteriovenous Malformation of the Ureter: A Rare Urological Entity Managed With Endoscopic Laser Ablation.","authors":"A Anber, J Kyeremeh, A Coscione, L Dragos, A Ahmed","doi":"10.1155/criu/3037053","DOIUrl":"10.1155/criu/3037053","url":null,"abstract":"<p><strong>Background: </strong>Arteriovenous malformations (AVMs) of the urinary tract are exceedingly rare, especially when arising from the ureter. Presenting often with haematuria and obstructive symptoms, these lesions pose diagnostic and therapeutic challenges, with no established management guidelines.</p><p><strong>Case presentation: </strong>We report a case of a 41-year-old woman who presented with left-sided flank pain, fever and visible haematuria. Initial imaging revealed hydronephrosis and a proximal ureteric soft tissue lesion. Flexible ureteroscopy identified a large, pale and fleshy intraluminal mass extending into the pelviureteric junction. Laser ablation and endoscopic resection were performed, and histopathology confirmed a polypoid AVM. Postoperative recovery was uneventful, apart from a conservatively managed renal abscess. The patient remained asymptomatic at 12-month follow-up.</p><p><strong>Conclusion: </strong>This case highlights a rare presentation of ureteric AVM and supports flexible ureteroscopy with laser ablation as a viable and minimally invasive treatment modality. Clinicians should consider vascular anomalies in patients with unexplained haematuria, particularly when conventional aetiologies are excluded.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"3037053"},"PeriodicalIF":0.0,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13084136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147723916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iatrogenic Amputation of the Distal Third of the Penis During Circumcision: Successful Reimplantation Without Magnification.","authors":"Hassami Sawadogo, Clotaire Alexis Marie Kiemdiba Donega Yaméogo, Abdoul-Karim Paré, Abdoul-Karim Ouattara, Fatao Ouédraogo, Harouna Gnanou, Brahima Kirakoya, Adama Ouattara","doi":"10.1155/criu/5856486","DOIUrl":"10.1155/criu/5856486","url":null,"abstract":"<p><strong>Background: </strong>Traumatic penile amputations, although rare, represent complex urological emergencies. Cases of iatrogenic origin secondary to circumcision are an exceptionally uncommon but serious etiology. The standard of treatment is microsurgery. However, in many contexts, particularly in developing countries, access to microsurgery is limited, leading surgical teams to resort to reimplantation techniques without microvascular anastomosis, with variable results.</p><p><strong>Case presentation: </strong>An 8-year-old boy was admitted to our department for complete amputation of the distal third of the penis during a circumcision. The amputated segment was preserved in saline solution. Emergency reimplantation was performed within a 3-h timeframe. The procedure included end-to-end urethrorrhaphy over a stent, cavernorrhaphy, and vascular alignment, all without the use of loupes or an operating microscope. The patient was discharged on the 25th postoperative day with a perfectly viable reimplanted segment and a satisfactory aesthetic and functional outcome.</p><p><strong>Conclusions: </strong>This case demonstrates that penile reimplantation can be successful in the absence of microsurgery in children, through meticulous technique and aggressive postoperative management of edema in settings with limited technological resources. It also serves as an urgent reminder of the absolute necessity to prevent these tragic accidents through the standardization and medicalization of circumcision practices. Long-term follow-up is essential to assess the erectile and voiding function of this patient.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"5856486"},"PeriodicalIF":0.0,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Port-Site Seeding of Urothelial Carcinoma After Robotic-Assisted Radical Prostatectomy Accompanied With Elevated Serum Levels of Carbohydrate Antigen 19-9: A Case Report.","authors":"Jun Kaneko, Sayuri Takahashi, Kazuyoshi Izukuri, Fusako Niimi, Mariko Tabata, Yuta Takeshima, Haruki Kume","doi":"10.1155/criu/1618695","DOIUrl":"10.1155/criu/1618695","url":null,"abstract":"<p><p>Urothelial carcinoma (UC) of the bladder has a high recurrence rate. Non-muscle-invasive bladder cancer (NMIBC) requires careful follow-up after transurethral resection (TUR). Some cases of extravesical recurrence of UC have been reported following radical cystectomy or nephroureterectomy; however, few such cases following robot-assisted radical prostatectomy (RARP) are known. A 77-year-old man presented to our hospital with high serum prostate-specific antigen (PSA) levels and atypical urothelial cells. Prostate biopsy and photodynamic diagnosis (PDD)-TURBT were performed. Pathological diagnoses were adenocarcinoma (Gleason score 3 + 4) of the prostate and UC (high grade, pT1 + Tis) of the bladder. Intravesical Bacillus Calmette-Guerin (BCG) was administered. One year after BCG therapy, examinations showed no evidence of UC recurrence; RARP was performed in another hospital on his will. Four months following RARP, elevated serum carbohydrate antigen 19-9 (CA19-9), palpable port-site subcutaneous indurations, and intraperitoneal nodules were detected by blood test and positron emission tomography/computed tomography (PET/CT). The subcutaneous indurations were pathologically diagnosed as UC. Platinum-based chemotherapy decreased the level of serum CA19-9. Cancer progression with the elevation of serum CA19-9 was observed during subsequent avelumab therapy, and enfortumab vedotin therapy was initiated. The patient died from cancer progression 30 months after extravesical recurrence of UC. RARP for patients with a past history of bladder tumor presents a risk of dissemination of UC due to urine leakage. Thorough examination for UC before RARP is recommended.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"1618695"},"PeriodicalIF":0.0,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13069178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147676391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early-Onset Bilateral Clear Cell Renal Cell Carcinoma in a Pediatric Renal Transplant Recipient: A Rare Case Report.","authors":"Ravi Kiran Gautam, Mahesh Bahadur Adhikari, Ajit Khadga, Bipin Maharjan, Pramesh Prasad Shrestha, Prashant Mishra, Deepak Kumar Yadav, Birodh Basnet, Subodh Ghimire, Arnab Singh Parmar","doi":"10.1155/criu/7275534","DOIUrl":"10.1155/criu/7275534","url":null,"abstract":"<p><strong>Background: </strong>Renal transplantation (RTx) is the preferred treatment for end-stage renal disease (ESRD), reducing mortality and improving quality of life. However, long-term immunosuppression increases the risk of malignancy, with renal cell carcinoma (RCC) occurring in approximately 0.6%-0.7% of renal transplant recipients, most commonly arising in the native kidneys. Bilateral RCC is rare and is typically associated with papillary histology and acquired cystic kidney disease (ACKD).</p><p><strong>Case presentation: </strong>A 16-year-old male with ESRD secondary to diffuse mesangial hypercellularity underwent living-related renal transplantation from his mother. Fourteen months posttransplant, routine ultrasonography revealed bilateral renal masses in the native kidneys. Contrast-enhanced computed tomography confirmed multiple lesions in both kidneys. The patient underwent bilateral laparoscopic nephrectomy. Histopathology revealed bilateral clear cell renal cell carcinoma, confined to the kidneys with negative surgical margins. Multiple benign cortical cysts suggested early acquired cystic kidney disease. At 1-year follow-up, the patient showed no evidence of recurrence, with normal serum creatinine and stable graft function.</p><p><strong>Discussion: </strong>Bilateral RCC after renal transplantation is rare and is usually associated with papillary histology and acquired cystic kidney disease. The early occurrence of bilateral clear cell RCC in a pediatric transplant recipient is unusual and may indicate an underlying predisposition. Early detection through routine imaging allowed timely surgical management with preservation of graft function.</p><p><strong>Conclusion: </strong>This case highlights the rare occurrence of early bilateral clear cell RCC in a pediatric renal transplant recipient. Careful surveillance of native kidneys in transplant recipients may facilitate early diagnosis and favorable outcomes.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"7275534"},"PeriodicalIF":0.0,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13067055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147677190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitomycin Gel for the Pyelocaliceal System in Patients With Urinary Diversion: First Reported Cases and Operative Technique.","authors":"Kai Wen Cheng, Grant Sajdak, Ala A Farkouh, Sikai Song, Brian Hu","doi":"10.1155/criu/2901637","DOIUrl":"10.1155/criu/2901637","url":null,"abstract":"<p><strong>Purpose: </strong>Mitomycin gel for the pyelocaliceal system (UGN-101) is an approved kidney-sparing therapy for upper tract urothelial carcinoma (UTUC). Little to no data exist on its safety and efficacy in patients with a history of urinary diversion. We report our experience with overcoming the anatomical challenges of UGN-101 instillation in patients with UTUC and prior history of radical cystectomy with urinary diversion.</p><p><strong>Materials and methods: </strong>Retrospective review was performed on all patients with pre-existing urinary diversion who underwent UGN-101 instillation for management of UTUC at a single academic institution. Surgical techniques for instillation are described, and the clinical course, including complications and disease status, are reported.</p><p><strong>Results: </strong>Two patients met inclusion criteria. One patient had carcinoma in situ in the renal pelvis and was treated with antegrade instillation via nephrostomy tube at an infusion clinic. The second patient had multifocal disease in the renal pelvis and the distal ureter and was treated with targeted antegrade instillation using an end-hole catheter. Both patients experienced infectious complications, and one had a ureteral stricture that resolved without intervention. No diversion-related complications were observed. Both patients are disease-free at last follow-up (10 months) on endoscopy and biopsy, although one patient required systemic immunotherapy.</p><p><strong>Conclusions: </strong>Our series highlights the potential role of UGN-101 in patients with UTUC and pre-existing urinary diversion. Antegrade instillation of UGN-101 can be tailored to specific disease locations and should be considered for patients with a history of urinary diversion who are not candidates for extirpative surgery.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"2901637"},"PeriodicalIF":0.0,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13051902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147634536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Testicular Regression Syndrome Presenting as a Nonpalpable Undescended Testis in Adulthood: A Case Report and Literature Review.","authors":"Bartholomeo Nicholaus Ngowi, Alex Mremi, Ester Lekei, Orgeness Mbwambo, Jay Lodhia","doi":"10.1155/criu/3994628","DOIUrl":"10.1155/criu/3994628","url":null,"abstract":"<p><p>Vanishing testis is also known as testicular regression syndrome, which is atrophy and disappearance of one testis during fetal life. Vanishing testis accounts for < 5% of undescended testis. Vanishing testis is a rare condition that must be remembered in the differential diagnosis of undescended testis. We report a case of vanishing testis in a young man of 29 years old who underwent inguinal exploration for nonpalpable undescended testis. There was no obvious testis at exploration and instead the vas deferens together with cord vessels ended blindly distally. The spermatic cord was excised and the patient fared well postoperatively.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"3994628"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13045270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147623874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}