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PROTECTIVE RAGE FRAGMENT INHIBITS AMYLOID BETA OLIGOMERIZATION 保护性rage片段抑制淀粉样蛋白寡聚化
Institute of information technology Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-1-4.19
T. D. Volkova, A. Avetisyan, D. Koroev, O. Volpina
{"title":"PROTECTIVE RAGE FRAGMENT INHIBITS AMYLOID BETA OLIGOMERIZATION","authors":"T. D. Volkova, A. Avetisyan, D. Koroev, O. Volpina","doi":"10.47501/978-5-6044060-1-4.19","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.19","url":null,"abstract":"The article discusses the involvement of beta-amyloid in the mechanism of the protective action of the synthetic RAGE fragment. It was shown that the peptide is able to suppress the formation of oligomers and fibrils of beta-amyloid in solution. This confirms the hypothesis that the protective activity of the peptide is associated with its ability to inhibit the process of oligomerization of beta-amyloid.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115722214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MICROSTRUCTURAL INDICATORS OF MUSCLE TISSUE WITH VARYING DEGREES OF SEVERITY OF MYOPATHY SIGNS IN FASTGROWING PIGS 快速生长猪不同程度肌病体征肌肉组织显微结构指标
Institute of information technology Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-1-4.29
V. Nasonova, A. A. Semenova, T. Kuznetsova, R. Nekrasov
{"title":"MICROSTRUCTURAL INDICATORS OF MUSCLE TISSUE WITH VARYING DEGREES OF SEVERITY OF MYOPATHY SIGNS IN FASTGROWING PIGS","authors":"V. Nasonova, A. A. Semenova, T. Kuznetsova, R. Nekrasov","doi":"10.47501/978-5-6044060-1-4.29","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.29","url":null,"abstract":"The article presents the criteria for determining the severity of myopathy by assessing the morphological features of muscle tissue. Since it is known that hybrid pigs are most susceptible to stress, which further leads to the development of dystrophic (myopathic) changes in the structure of muscle tissue, which subsequently reduce the quality of pork.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"248 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116072581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
METHODOLOGICAL APPROACHES TO IDENTIFICATION AND DETECTION OF FALSE FOOD FISH PRODUCTS 鉴定和检测假食用鱼产品的方法学方法
Institute of information technology Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-1-4.28
L. Abramova, A. Kozin
{"title":"METHODOLOGICAL APPROACHES TO IDENTIFICATION AND DETECTION OF FALSE FOOD FISH PRODUCTS","authors":"L. Abramova, A. Kozin","doi":"10.47501/978-5-6044060-1-4.28","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.28","url":null,"abstract":"The article discusses the problem of creating objective methods for assessing the quality of fish raw materials. The NMR method is recommended for a comprehensive analysis of the metabolic profile of salmon and cod fish species in order to characterize the qualitative indicators and identify the species composition.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125013298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MEMBRANE TESTS FOR IDENTIFICATION OF RAW MATERIALS IN MEAT PRODUCTS 肉制品原料鉴别的膜试验
Institute of information technology Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-1-4.32
E. Zvereva, O. Hendrickson, D. Popravko, A. Zherdev, B. Dzantiev
{"title":"MEMBRANE TESTS FOR IDENTIFICATION OF RAW MATERIALS IN MEAT PRODUCTS","authors":"E. Zvereva, O. Hendrickson, D. Popravko, A. Zherdev, B. Dzantiev","doi":"10.47501/978-5-6044060-1-4.32","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.32","url":null,"abstract":"Membrane test systems have been developed for rapid out-of-laboratory identification of raw meat using immunochromatographic detection of protein biomarkers – troponin I, myoglobin, immunoglobulin. Their effectiveness has been shown for the control of various types of meat-containing products.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116833033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ANTITUMOR EFFECT OF NITRIC OXIDE (NO) DONORS AND MECHANISMS OF ITS IMPLEMENTATION 一氧化氮供体的抗肿瘤作用及其作用机制
Institute of information technology Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-1-4.23
V. Deryagina, N. Ryzhova, Lyudmila Savluchinskaya, L. Krivosheeva, K. Kirsanov
{"title":"ANTITUMOR EFFECT OF NITRIC OXIDE (NO) DONORS AND MECHANISMS OF ITS IMPLEMENTATION","authors":"V. Deryagina, N. Ryzhova, Lyudmila Savluchinskaya, L. Krivosheeva, K. Kirsanov","doi":"10.47501/978-5-6044060-1-4.23","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.23","url":null,"abstract":"The review discusses literature data and the results of our own studies on the role of nitric oxide in carcinogenesis. The antitumor potential of classical NO donors as cytotoxic compounds and modulators of signaling oncogenic pathways is analyzed.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117087177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DEREGULATORY ACTION OF ENDOCRINE DISRUPTOR DDT ON MORPHOGENESIS AND FUNCTION OF ADRENAL ZONA GLOMERULOSA 内分泌干扰物DDT对肾小球肾上腺带形态发生及功能的调控作用
Institute of information technology Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-1-4.11
S. Nazimova, N. Yaglova, D. Tsomartova, S. Obernikhin, V. Yaglov
{"title":"DEREGULATORY ACTION OF ENDOCRINE DISRUPTOR DDT ON MORPHOGENESIS AND FUNCTION OF ADRENAL ZONA GLOMERULOSA","authors":"S. Nazimova, N. Yaglova, D. Tsomartova, S. Obernikhin, V. Yaglov","doi":"10.47501/978-5-6044060-1-4.11","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.11","url":null,"abstract":"Exposure to endocrine disruptor DDT impairs development of adrenal zona glomerulosa by higher expression of pluripotency factors along with the suppression of factors that ensure the maturation of cortical cells. It leads to a decrease in aldosterone production and compensatory hyperplasia of zona glomerulosa.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114692005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NONSYMBIOTIC HEMOGLOBIN TRIGGERS PHOTOBIOMODULATION OF SEEDS 非共生血红蛋白触发种子的光生物调节
Institute of information technology Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-1-4.53
О. Tiflova, A. Dmitriev
{"title":"NONSYMBIOTIC HEMOGLOBIN TRIGGERS PHOTOBIOMODULATION OF SEEDS","authors":"О. Tiflova, A. Dmitriev","doi":"10.47501/978-5-6044060-1-4.53","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.53","url":null,"abstract":"The possibility of photobiomodulation of triticale seeds under the action of laser radiation with the parameters appropriate to spectral and kinetic characteristics of non symbiotic hemoglobin – potential O2-provider for 2-oxoglutarate/Fe(II)-dependent dioxygenases under hypoxia, has been revealed.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126196013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE DEGREE OF OXIDATIVE DAMAGE TO DNA IN VITRO AS A MOLECULAR PREDICTOR OF DISORDERS CAUSED BY EPIGENETIC AND EXOGENOUS FACTORS 体外DNA氧化损伤程度作为表观遗传和外源性因素引起的疾病的分子预测因子
Institute of information technology Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-1-4.49
E. Tekutskaya, I. Raybova, L. Gusaruk
{"title":"THE DEGREE OF OXIDATIVE DAMAGE TO DNA IN VITRO AS A MOLECULAR PREDICTOR OF DISORDERS CAUSED BY EPIGENETIC AND EXOGENOUS FACTORS","authors":"E. Tekutskaya, I. Raybova, L. Gusaruk","doi":"10.47501/978-5-6044060-1-4.49","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.49","url":null,"abstract":"In this work, we studied the mechanisms of oxidative damage to DNA molecules isolated from whole blood of healthy donors and patients with epigenetic disease (epidermolysis bullosa) when exposed to an alternating magnetic field of low frequency in vitro, associated with the formation of reactive oxygen species.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"58 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123225782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NITRIC OXIDE IN BLOOD VESSELS AND BRAIN IN NORMAL AND IN HYPOXIA / ISCHEMIA 正常和缺氧/缺血时血管和脑中的一氧化氮
Institute of information technology Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-1-4.21
V. Reutov, Elena Sorokina
{"title":"NITRIC OXIDE IN BLOOD VESSELS AND BRAIN IN NORMAL AND IN HYPOXIA / ISCHEMIA","authors":"V. Reutov, Elena Sorokina","doi":"10.47501/978-5-6044060-1-4.21","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.21","url":null,"abstract":"The review presents an analysis and generalization of literature data and the results of our own studies on the mechanisms of action of nitric oxide on blood vessels and the brain under normal physiological conditions, as well as during hypoxia / ischemia.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132754305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MECHANISMS OF FRACTIONATION OF STABLE ISOTOPES IN LIVING SYSTEMS 稳定同位素在生命系统中的分馏机制
Institute of information technology Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-1-4.17
S. Dzhimak, A. Elkina, A. Basov
{"title":"MECHANISMS OF FRACTIONATION OF STABLE ISOTOPES IN LIVING SYSTEMS","authors":"S. Dzhimak, A. Elkina, A. Basov","doi":"10.47501/978-5-6044060-1-4.17","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.17","url":null,"abstract":"Some physical laws are considered that provide stable fractionation of isotopes, leading to the accumulation of certain isotopic forms in the intracellular and intercellular space with the manifestation of these effects at various levels of the organism. It is suggested that for a more complete understanding of the above processes, it is necessary to study the mechanism of exchange interaction between particles with integer spin (bosons) and half-integer spin (fermions).","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116031679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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