内分泌干扰物DDT对肾小球肾上腺带形态发生及功能的调控作用

Institute of information technology Pub Date : 1900-01-01 DOI:10.47501/978-5-6044060-1-4.11

S. Nazimova, N. Yaglova, D. Tsomartova, S. Obernikhin, V. Yaglov

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引用次数: 0

摘要

暴露于内分泌干扰物DDT会通过提高多能性因子的表达，同时抑制确保皮质细胞成熟的因子，从而损害肾上腺肾小球带的发育。它导致醛固酮产生减少和肾小球带代偿性增生。

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DEREGULATORY ACTION OF ENDOCRINE DISRUPTOR DDT ON MORPHOGENESIS AND FUNCTION OF ADRENAL ZONA GLOMERULOSA

Exposure to endocrine disruptor DDT impairs development of adrenal zona glomerulosa by higher expression of pluripotency factors along with the suppression of factors that ensure the maturation of cortical cells. It leads to a decrease in aldosterone production and compensatory hyperplasia of zona glomerulosa.

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Institute of information technology

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