{"title":"EFFECT OF RHAPONTICUM CARTHAMOIDES AND CRANBERRY MEAL EXTRACTS COMPOSITION ON GLUCOSE LEVEL","authors":"D. Khalikova, S. Ankov, T. Tolstikova","doi":"10.47501/978-5-6044060-1-4.26","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.26","url":null,"abstract":"It has been found that Rhaponticum carthamoides and cranberry meal extracts composition at an effective dose of 35:250 mg/kg after 14 days of oral administration to mice promotes a significant glucose level reduction on the background of physical and glucose challenge compared to intact control.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133171264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EXPERIENCE IN USING INFORMATION AND COMMUNICATION TECHNOLOGIES IN CLINICAL PRACTICE AND EDUCATIONAL PROCESS","authors":"V. Y. Zobenko, Alexandra Zobenko, Yuri Vasiliev","doi":"10.47501/978-5-6044060-1-4.37","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.37","url":null,"abstract":"The article pays attention to modern information technologies that allow distance learning among students in higher educational institutions. Describes the role of modern technologies, information and communication, in the education system and the practice of a doctor. The ex-perience of introducing telecommunication technologies for holding meetings with participants in the educational and medical process is described.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126452535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Semenova, Yulia Konstantinovna Yushina, M. Grudistova, E. Zaiko, O. E. Ivanova
{"title":"STUDY OF MICROBIAL COMMUNITIES IN MEAT PROCESSING ENTERPRISES","authors":"A. Semenova, Yulia Konstantinovna Yushina, M. Grudistova, E. Zaiko, O. E. Ivanova","doi":"10.47501/978-5-6044060-1-4.30","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.30","url":null,"abstract":"The article discusses the results of a study of the microbial diversity of objects in the production environment of two meat processing enterprises, including antibiotic resistance, isolated strains of pathogenic microorganisms and their ability to biofilm formation.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131438488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Petrov, Yuliya S Sidorova, A. Kochetkova, V. Mazo
{"title":"DEVELOPMENT AND IN VIVO EVALUATION OF COMPLEXES OF BIOLOGICALLY ACTIVE COMPOUNDS WITH BIOPOLYMER MATRICES","authors":"N. Petrov, Yuliya S Sidorova, A. Kochetkova, V. Mazo","doi":"10.47501/978-5-6044060-1-4.36","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.36","url":null,"abstract":"The paper presents the results of a preclinical assessment of the effectiveness of food ingredients: a concentrate of blueberry leaf polyphenols sorbed on buckwheat flour, and a concentrate of phytoecdysteroid 20-hydroxyecdysone and quinoa grain flavonoids sorbed on chicken egg white.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121641174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Sorokina, Z. Semenova, V. I. Lukianov, O. Karaseva, S. A. Afanasieva, V. Reutov, L. Roshal, V. Pinelis
{"title":"BIOCHEMICAL PREDICTORS OF EARLY AND LONG-TERM OUTCOMES OF TRAUMATIC BRAIN INJURY IN CHILDREN","authors":"E. Sorokina, Z. Semenova, V. I. Lukianov, O. Karaseva, S. A. Afanasieva, V. Reutov, L. Roshal, V. Pinelis","doi":"10.47501/978-5-6044060-1-4.24","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.24","url":null,"abstract":"In children with mild and severe traumatic brain injury (TBI), the role of various damage/repair neuromarkers in the outcomes of trauma was studied. It has been shown that in the first days after TBI with adverse outcomes, there was a significant increase in NSE, S100b, NO products and a decrease in the content of BDNF and autoantibodies to NMDA (NR2) glutamate receptors (Glu) in the blood serum. After 6 months with unfavorable outcomes, there was an increase in aAb to S100b and a decrease in BDNF.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"124 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123250206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ADDITIONAL METAL-BINDING CENTERS IN PROTEINS: DAMAGE OR PROTECTION?","authors":"O. Kosmachevskaya, N. Novikova, A. Topunov","doi":"10.47501/978-5-6044060-1-4.44","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.44","url":null,"abstract":"The problem of the formation of additional metal-binding centers in proteins under conditions of increased production of reactive species is considered. In some cases, the formation of a complex of a metal with a post-translationally altered protein is a modulation mechanism its activity and stability.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115691855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Tsomartova, E. Timokhina, N. Yaglova, S. Obernikhin, V. Yaglov
{"title":"MITOTIC ACTIVITY OF LYMPHOCYTES IN PREPUBERTAL RATS EXPOSED TO LOW DOSES OF DDT","authors":"D. Tsomartova, E. Timokhina, N. Yaglova, S. Obernikhin, V. Yaglov","doi":"10.47501/978-5-6044060-1-4.13","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.13","url":null,"abstract":"Low-dose developmental exposure to DDT results in inhibited mitotic activity of thymic lymphocytes in prepubertal rats. Decreased number of proliferating cells in deeper layers of the cortex and in the medulla, not subcapsular lymphoblasts, contributes to lowered proliferation rate.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122725701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Tsomartova, N. Yaglova, S. Obernikhin, S. Nazimova, V. Yaglov
{"title":"ALTERED CYTOPHYSIOLOGY OF EPINEPHRINE-PRODUCING CELLS IN RATS AFTER CHRONIC EXPOSURE TO LOW DOSES OF DDT","authors":"D. Tsomartova, N. Yaglova, S. Obernikhin, S. Nazimova, V. Yaglov","doi":"10.47501/978-5-6044060-1-4.12","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.12","url":null,"abstract":"Chronic low-dose exposure to dichlorodiphenyltrichloroethane does not diminish epinephrine production since epinephrine-secreting adrenal cells significantly intensify mitochondrial ac-tivity to restore epinephrine secretion.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125125101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"OSTEOCHONDROSIS OF THE SPINE - A FACTOR OF PREMATURE AGING OF A PERSON","authors":"A. Cherkasov","doi":"10.47501/978-5-6044060-1-4.14","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.14","url":null,"abstract":"With the help of MRI and X-ray studies, carried out for 20 years, it was found that osteochondrosis of the spine is not only a manifestation of premature aging of bone and cartilage tissue, but also a pathological factor leading to premature and painful aging of a person.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123912537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Volpina, D. Koroev, T. D. Volkova, A. Kamynina, M. Serebryakova, N. Bobkova
{"title":"RESISTANCE TO PROTEOLISYS AND BIOLOGICAL ACTIVITY OF RAGE FRAG-MENTS","authors":"O. Volpina, D. Koroev, T. D. Volkova, A. Kamynina, M. Serebryakova, N. Bobkova","doi":"10.47501/978-5-6044060-1-4.20","DOIUrl":"https://doi.org/10.47501/978-5-6044060-1-4.20","url":null,"abstract":"It was shown the correlation between the resistance to proteolysis of (60-76) RAGE fragment and its protected analogue, formation of their fragments and revealed biological activity. We assumed that protected RAGE fragment is a promising for development of anti-AD therapy.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126016226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}