THE DEGREE OF OXIDATIVE DAMAGE TO DNA IN VITRO AS A MOLECULAR PREDICTOR OF DISORDERS CAUSED BY EPIGENETIC AND EXOGENOUS FACTORS

E. Tekutskaya, I. Raybova, L. Gusaruk
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Abstract

In this work, we studied the mechanisms of oxidative damage to DNA molecules isolated from whole blood of healthy donors and patients with epigenetic disease (epidermolysis bullosa) when exposed to an alternating magnetic field of low frequency in vitro, associated with the formation of reactive oxygen species.
体外DNA氧化损伤程度作为表观遗传和外源性因素引起的疾病的分子预测因子
在这项工作中,我们研究了从健康供体和表观遗传疾病(大疱性表皮松解症)患者全血中分离的DNA分子暴露于体外低频交变磁场时氧化损伤的机制,并与活性氧的形成相关。
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