IF 19.1 1区化学

Chem Pub Date : 2026-09-10 Epub Date: 2026-04-10 DOI: 10.1016/j.chempr.2026.103023

Yongkang Wang, Yair Litman, Minhaeng Cho, Stephen J. Cox, Mischa Bonn

{"title":"Wetting transparency of graphene across length scales: Macroscopic transparency but nanoscopic mirror-like behavior","authors":"Yongkang Wang, Yair Litman, Minhaeng Cho, Stephen J. Cox, Mischa Bonn","doi":"10.1016/j.chempr.2026.103023","DOIUrl":"10.1016/j.chempr.2026.103023","url":null,"abstract":"<div><div>Graphene supported on a substrate in contact with water underpins a wide range of processes and technologies, yet its wettability remains controversial. Understanding how substrate charges and graphene’s properties influence water organization is crucial. Here, we combine heterodyne-detected sum-frequency generation (HD-SFG) spectroscopy with molecular dynamics simulations to investigate CaF<sub>2</sub>-supported graphene interfaces in contact with water. We find that the interfacial water orientation is primarily governed by the CaF<sub>2</sub> substrate’s pH-dependent local electrostatics, confirming graphene’s macroscopic wetting transparency. However, at the nanoscale, graphene’s polarizability gives rise to a local reorientation of interfacial water above substrate charges, partially counteracting the electrostatic field originating from the substrate and revealing a subtle structural ordering that is masked in spatially averaged measurements. These insights elucidate the molecular origins of graphene’s wetting behavior and suggest new avenues for tailoring interfacial phenomena in graphene-based nanofluidic, sensing, and energy applications.</div></div>","PeriodicalId":268,"journal":{"name":"Chem","volume":"12 9","pages":"Article 103023"},"PeriodicalIF":19.1,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148940613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Catalysis engineering at the forefront of the chemical and energy transition 催化工程处于化学和能源转型的前沿

IF 19.1 1区化学

Chem Pub Date : 2026-09-10 DOI: 10.1016/j.chempr.2026.103245

Jingxiu Xie

引用次数: 0

Chem at 10: Sarbajit Banerjee

IF 19.1 1区化学

Chem Pub Date : 2026-09-10 DOI: 10.1016/j.chempr.2026.103161

Sarbajit Banerjee

引用次数: 0

Electrochemical reductive carboxylation with carbon dioxide using water as the reductant 以二氧化碳为还原剂的电化学还原羧化反应

IF 19.1 1区化学

Chem Pub Date : 2026-09-10 Epub Date: 2026-03-30 DOI: 10.1016/j.chempr.2026.103002

Can-Ming Zhu, Jun-Li Li, Hao-Yuan Li, Huai-Gui Li, Tao Wen, Xiaofu Sun, Qing-Yuan Meng

引用次数: 0

Polymerase-mediated expansion of DNA nanostructures 聚合酶介导的DNA纳米结构扩增

IF 19.1 1区化学

Chem Pub Date : 2026-09-10 Epub Date: 2026-04-21 DOI: 10.1016/j.chempr.2026.103038

Hong Kang, Yuexuan Yang, Qishu Zhang, Qi Yan, Bryan Wei

引用次数: 0

Out-of-equilibrium confinement catalysis mediated by compressive force 压缩力介导的非平衡约束催化

IF 19.1 1区化学

Chem Pub Date : 2026-09-10 Epub Date: 2026-04-17 DOI: 10.1016/j.chempr.2026.103026

Fang-Zi Liu, Shi Li, Yufei Zhu, Yan Liu, Jian Wang, Heather J. Kulik, KaKing Yan

{"title":"Out-of-equilibrium confinement catalysis mediated by compressive force","authors":"Fang-Zi Liu, Shi Li, Yufei Zhu, Yan Liu, Jian Wang, Heather J. Kulik, KaKing Yan","doi":"10.1016/j.chempr.2026.103026","DOIUrl":"10.1016/j.chempr.2026.103026","url":null,"abstract":"<div><div>Biological systems sustain non-equilibrium states through continuous energy inputs such as light or chemical fuels, whereas synthetic systems typically dissipate energy toward equilibrium. Here, we demonstrate that mechanical force delivered via ball milling serves as a unique energy source to drive endergonic coordination self-assembly inaccessible through conventional stimuli. Mechanistic studies combining ball-milling kinetics, model reactions, and density functional theory (DFT) calculations reveal that direct mechanical impact strongly deforms coordination cages, elevating their ground-state energies. These distorted cages enable barrier-free guest release, followed by cage reassembly. By coupling this force-driven step with a subsequent equilibrium process, two unprecedented outcomes are achieved: (1) an out-of-equilibrium catalytic confinement cycle and (2) a dissipative cycle. Notably, this mechanochemical strategy circumvents product inhibition in equilibrium-based supramolecular systems, enabling transformations with up to 85 catalytic turnovers. Our work highlights mechanical force as a design principle for non-equilibrium chemistry toward life-like systems.</div></div>","PeriodicalId":268,"journal":{"name":"Chem","volume":"12 9","pages":"Article 103026"},"PeriodicalIF":19.1,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147709069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Single-molecule FRET enables the detection of site-specific α-synuclein serine phosphorylation 单分子FRET能够检测位点特异性α-突触核蛋白丝氨酸磷酸化

IF 19.1 1区化学

Chem Pub Date : 2026-09-10 Epub Date: 2026-04-16 DOI: 10.1016/j.chempr.2026.103030

Moon Hyeok Choi, Mike Filius, Senne Klomp, Yen Way Isabell Trinh, Adam Pomorski, Chirlmin Joo

{"title":"Single-molecule FRET enables the detection of site-specific α-synuclein serine phosphorylation","authors":"Moon Hyeok Choi, Mike Filius, Senne Klomp, Yen Way Isabell Trinh, Adam Pomorski, Chirlmin Joo","doi":"10.1016/j.chempr.2026.103030","DOIUrl":"10.1016/j.chempr.2026.103030","url":null,"abstract":"<div><div>Phosphorylation, a key posttranslational modification, plays a crucial role in regulating protein function and stability. However, conventional ensemble assays, such as ELISA, are unable to resolve phosphorylation at the proteoform level, thereby obscuring the heterogeneity of site-specific modifications. To address this limitation, we present a single-molecule analysis platform that combines site-specific labeling of phosphorylation sites with fluorescence resonance energy transfer (FRET) to pinpoint the location of phosphorylation sites in full-length proteins. We demonstrate the applicability of our approach on α-synuclein (αSyn), a protein implicated in neurodegenerative diseases. We can quantify the number of phosphorylation sites and identify which amino acids are phosphorylated on αSyn, depending on the type of kinase used. This single-molecule platform achieves picomolar (pM) sensitivity, enabling the detection of distinct phosphorylated proteoforms that are beyond the reach of conventional ensemble methods. Our approach enables detailed analysis of protein modifications in neurodegenerative diseases and may aid biomarker discovery.</div></div>","PeriodicalId":268,"journal":{"name":"Chem","volume":"12 9","pages":"Article 103030"},"PeriodicalIF":19.1,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147709280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regulating transport processes in oxygen evolution catalyst layers for proton exchange membrane water electrolysis 质子交换膜电解析氧催化剂层中输运过程的调控

IF 19.1 1区化学

Chem Pub Date : 2026-09-10 Epub Date: 2026-08-17 DOI: 10.1016/j.chempr.2026.103198

Muhammad Irfansyah Maulana, Abdulrahman Allangawi, Zhi-Peng Wu, Zhiping Lai, Nikos Hadjichristidis, Xin-Yao Yu, Huabin Zhang

{"title":"Regulating transport processes in oxygen evolution catalyst layers for proton exchange membrane water electrolysis","authors":"Muhammad Irfansyah Maulana, Abdulrahman Allangawi, Zhi-Peng Wu, Zhiping Lai, Nikos Hadjichristidis, Xin-Yao Yu, Huabin Zhang","doi":"10.1016/j.chempr.2026.103198","DOIUrl":"10.1016/j.chempr.2026.103198","url":null,"abstract":"<div><div>Proton exchange membrane water electrolysis (PEMWE) has emerged as a promising platform for sustainable hydrogen production. However, its large-scale implementation is constrained by the high cost and inefficient utilization of iridium (Ir)-based oxygen evolution reaction (OER) catalysts. Beyond intrinsic catalytic activity, the performance of a practical membrane electrode assembly is governed by the interplay of multiple transport processes within the anode catalyst layer, including water delivery, oxygen removal, proton conduction, and electron transport. This review presents a transport-oriented framework for the rational design of OER catalyst layers in PEMWE. We first elucidate the fundamental transport mechanisms and their limitations during OER electrocatalysis, followed by recent advances in transport regulation through four key strategies: catalyst architecture, ionomer engineering, hierarchical pore design, and interface engineering. Finally, we summarize emerging design principles and outline future directions for developing ultralow-Ir, transport-efficient OER catalyst layers that enable scalable, durable, and economically viable PEMWE.</div></div>","PeriodicalId":268,"journal":{"name":"Chem","volume":"12 9","pages":"Article 103198"},"PeriodicalIF":19.1,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148756631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advanced bottom-up synthetic chemistry expanding the MXene family 先进的自下而上的合成化学扩展了MXene家族

IF 19.1 1区化学

Chem Pub Date : 2026-09-10 DOI: 10.1016/j.chempr.2026.103253

Wenyu Xu, Hongbo Ding, Xinliang Li

引用次数: 0

Emerging trends in light harnessing for CO2 reduction using photocatalytic MOFs 利用光催化mof减少二氧化碳的光利用新趋势

IF 19.1 1区化学

Chem Pub Date : 2026-09-10 Epub Date: 2026-05-20 DOI: 10.1016/j.chempr.2026.103044

Arthur Reymond, Almudena Marti, Ekaterina Chernova, Pedro Vidinha, Stefan Wuttke, Robert Wojcieszak

{"title":"Emerging trends in light harnessing for CO2 reduction using photocatalytic MOFs","authors":"Arthur Reymond, Almudena Marti, Ekaterina Chernova, Pedro Vidinha, Stefan Wuttke, Robert Wojcieszak","doi":"10.1016/j.chempr.2026.103044","DOIUrl":"10.1016/j.chempr.2026.103044","url":null,"abstract":"<div><div>Photocatalytic carbon dioxide (CO<sub>2</sub>) reduction, mimicking photosynthesis, emerges as a promising carbon capture and utilization (CCU) approach. This technology leverages innovative photocatalytic materials, particularly metal-organic frameworks (MOFs), to efficiently convert CO<sub>2</sub> into fuels by using light energy. MOFs, with their tunable structure, high surface area, and ability to incorporate co-catalysts, offer significant advantages for this process. However, a key challenge remains—inefficient light utilization, as many MOF photocatalysts primarily absorb ultraviolet (UV) light, a small fraction of the solar spectrum. This perspective explores emerging trends in light-harvesting strategies to overcome this limitation and maximize the efficiency of MOF-based photocatalytic CO<sub>2</sub> reduction. We discuss sensitization strategies (dye, quantum dot [QD], and plasmon enhancement), MOF structure engineering (light-harvesting antennae, hierarchical architectures, and thin films), and innovative concepts beyond single-photon excitation (upconversion and triplet-triplet annihilation [TTA]). Improving light harvesting is essential for unlocking the full potential of MOF-based photocatalysis, enabling sustainable CO<sub>2</sub> conversion.</div></div>","PeriodicalId":268,"journal":{"name":"Chem","volume":"12 9","pages":"Article 103044"},"PeriodicalIF":19.1,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148940620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chem最新文献