Carbohydrate Polymers最新文献_第2页

Dopamine-functionalized chondroitin sulfate/gelatin-based composite hydrogels for enhancing wound healing and bone regeneration 多巴胺功能化硫酸软骨素/明胶复合水凝胶促进伤口愈合和骨再生

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-05-24 DOI: 10.1016/j.carbpol.2025.123809

Jian Yang , Jiale Jin , Haojie Yu , Yun Wang , Li Wang , Xiaowei Liu , Dongyu Wang , Yudi Huang , Chenguang Ouyang , Yu Wang , Yichuan Hong , Shuning Ren , Jian Hu , Jingyi Feng

{"title":"Dopamine-functionalized chondroitin sulfate/gelatin-based composite hydrogels for enhancing wound healing and bone regeneration","authors":"Jian Yang , Jiale Jin , Haojie Yu , Yun Wang , Li Wang , Xiaowei Liu , Dongyu Wang , Yudi Huang , Chenguang Ouyang , Yu Wang , Yichuan Hong , Shuning Ren , Jian Hu , Jingyi Feng","doi":"10.1016/j.carbpol.2025.123809","DOIUrl":"10.1016/j.carbpol.2025.123809","url":null,"abstract":"<div><div>Severe trauma not only damages the skin, but also affects the bones, causing osteoarthritis or bone defects. Traditional treatment strategies (such as sutures, metal stents, <em>etc.</em>) have problems with the need for a second surgery and difficulty in degradation, which cannot meet the treatment expectations of clinical doctors well. As the novel biomedical material, hydrogels have great potential in the treatment of bone defects due to the advantages of seamless filling, degradability and easy operation. Here, we designed a composite hydrogel (Gel-Gym/HS-Dopa) composed of glycidyl methacrylate-modified gelatin (Gel-Gym) and dopamine-functionalized chondroitin sulfate (HS-Dopa). The hydrogel exhibited good tissue adhesion, self-healing, biodegradability, anti-inflammatory and biocompatibility. In animal experiments, Gel-Gym/HS-Dopa hydrogel could significantly promote the rat skin wound healing and bone defect reconstruction <em>in vivo</em>. Therefore, the hydrogel was promising as a potential deep trauma dressing.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"366 ","pages":"Article 123809"},"PeriodicalIF":10.7,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144178569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cellulose-based bipolar heterogeneous membranes with two-dimensional lamellar composite three-dimensional network structure for osmotic energy conversion 纤维素基双极性非均相膜的二维片层复合三维网络结构渗透能转换

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-05-24 DOI: 10.1016/j.carbpol.2025.123804

Xiao Zhang, Haocun Huang, Xiaoyu Huang, Kexin Sun, Chunli Yao, Yanglei Xu, Feng Xu

{"title":"Cellulose-based bipolar heterogeneous membranes with two-dimensional lamellar composite three-dimensional network structure for osmotic energy conversion","authors":"Xiao Zhang, Haocun Huang, Xiaoyu Huang, Kexin Sun, Chunli Yao, Yanglei Xu, Feng Xu","doi":"10.1016/j.carbpol.2025.123804","DOIUrl":"10.1016/j.carbpol.2025.123804","url":null,"abstract":"<div><div>Reverse electrodialysis (RED) technology is extremely promising in harvesting osmotic energy. The exchange membranes, which are the core components of RED systems, especially in the investigation of composite membrane systems, remain a challenge by balancing the key requirements of better compatibility and sufficient stability, ease of fabrication, etc. In view of the excellent compatibility and stability of forest biomass membrane materials, this work reports a two-dimensional (2D) lamellar regenerated cellulose (RC) composite with a three-dimensional (3D) network of bacterial cellulose membrane doped with alkali lignin (BC-AL) heterogeneous membrane. The 2D lamellar structure provides nano-confined channels with high ionic flux, while the asymmetric structure formed by compositing with the 3D porous spatial network positively reduces the energy barrier and effectively weakens the concentration polarization effect to a certain extent, which also results in the formation of bipolar surfaces. Moreover, the large negative charges on the surface of the composite membrane enhance the cation selectivity and ion diffusion rate. The heterogeneous membrane is more advantageous for osmotic energy harvesting, achieving a power density of nearly 2 W·m<sup>−2</sup> under alkaline conditions. Both experimental and simulation analysis have demonstrated the significant potential of this structured heterogeneous membrane in the field of osmotic energy harvesting.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"365 ","pages":"Article 123804"},"PeriodicalIF":10.7,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144178567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The regulatory effects of butyrylated starch on gut microbiota and metabolites during in vitro fermentation: advantages over exogenous butyrate and resistant starch 丁酸淀粉对体外发酵过程中肠道菌群和代谢物的调节作用：优于外源丁酸和抗性淀粉

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-05-23 DOI: 10.1016/j.carbpol.2025.123791

Yi Zhang , Lingjin Li , Yahui Gao , Li Cheng , Yan Hong , Zhengbiao Gu

{"title":"The regulatory effects of butyrylated starch on gut microbiota and metabolites during in vitro fermentation: advantages over exogenous butyrate and resistant starch","authors":"Yi Zhang , Lingjin Li , Yahui Gao , Li Cheng , Yan Hong , Zhengbiao Gu","doi":"10.1016/j.carbpol.2025.123791","DOIUrl":"10.1016/j.carbpol.2025.123791","url":null,"abstract":"<div><div>Butyrylated normal maize starch (BNMS) is a butyrate-carrying and resistant starch (RS). BNMS is fermented by the gut microbiota to produce large amounts of short-chain fatty acids (SCFAs), particularly butyrate, which are beneficial for intestinal health. However, the effects of BNMS on gut microbiota and metabolites, and its advantages over exogenous butyrate and RS, are unclear. The specific effects of BNMS were investigated <em>via in vitro</em> fermentation using sodium butyrate (SB) and high-amylose maize starch (HAMS) as controls. Compared to SB and HAMS, BNMS enhanced gas production, lowered pH, and produced numerous SCFAs. Additionally, BNMS effectively stimulated beneficial bacteria proliferation, including <em>Coprococcus</em>, <em>Faecalibacterium</em>, <em>Megamonas</em>, <em>Collinsella</em>, <em>Blautia</em>, and <em>Bifidobacterium</em>, and suppressed harmful bacteria proliferation, including <em>Escherichia-shigella</em> and <em>Desulfovibrio</em>, resulting in a healthier colony structure. Similarly, BNMS modulated many amino acids, neurotransmitters, vitamins, sphingolipids, carbohydrates, hormones levels, and multiple metabolic pathways, including arginine and proline metabolism, tryptophan metabolism, synaptic vesicle cycle, sphingolipid metabolism, riboflavin metabolism, amino sugar and nucleotide sugar metabolism, and steroid hormone biosynthesis. Overall, BNMS positively affected gut microbiota and metabolites, exhibiting advantages over exogenous butyrate and RS. These results provide some theoretical basis for the BNMS development and application as a functional food.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"364 ","pages":"Article 123791"},"PeriodicalIF":10.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144134936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Baricitinib-loaded separable microneedle array patch (S-MAP) based on hyaluronic acid for alopecia areata therapy 基于透明质酸的载baricitinib可分离微针阵列贴片（S-MAP）治疗斑秃

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-05-23 DOI: 10.1016/j.carbpol.2025.123789

Da In Jeong , Song Yi Lee , Sungyun Kim , Su-Min Jo , HeeSeon Yang , Jieun You , ChaeRim Hwang , Ji Won Huh , Yeoung Eun Choi , Wonjun Jo , In-Jeong Choi , Hae-Jin Hu , Seung-Ki Baek , Woonsung Na , Jung-Hwan Park , Hyun-Jong Cho

{"title":"Baricitinib-loaded separable microneedle array patch (S-MAP) based on hyaluronic acid for alopecia areata therapy","authors":"Da In Jeong , Song Yi Lee , Sungyun Kim , Su-Min Jo , HeeSeon Yang , Jieun You , ChaeRim Hwang , Ji Won Huh , Yeoung Eun Choi , Wonjun Jo , In-Jeong Choi , Hae-Jin Hu , Seung-Ki Baek , Woonsung Na , Jung-Hwan Park , Hyun-Jong Cho","doi":"10.1016/j.carbpol.2025.123789","DOIUrl":"10.1016/j.carbpol.2025.123789","url":null,"abstract":"<div><div>Separable and dissolvable microneedle array patch based primarily on hyaluronic acid is designed for the topical delivery of baricitinib in alopecia areata (AA) therapy. Locoregional application of a separable microneedle array patch (S-MAP) may avoid the systemic side effects of oral administration and can be administered without pain compared with typical intradermal injections. Baricitinib (which has poor aqueous solubility) is evenly suspended with sodium carboxymethylcellulose. Subsequently, the mixture is blended with other pharmaceutical excipients, such as hyaluronic acid, sucrose, and Tween 80, to fabricate the S-MAP. Crystalline baricitinib transformed into an amorphous state during the drying process, which may have contributed to complete drug dissolution in the aqueous buffer within 60 min. Proper insertion of a baricitinib-loaded S-MAP into porcine skin tissue and mouse skin is demonstrated using optical coherence tomography and near-infrared fluorescence imaging, respectively. Topical administration of the baricitinib-loaded S-MAP system to the AA lesion of mouse models resulted in significantly higher hair growth compared with the control group (S-MAP: 82 % <em>vs.</em> control: 31 %, <em>p</em> < 0.05). These findings suggest that the baricitinib S-MAP system can be used efficiently and safely, while affording pain-free and self-medication properties, for the AA therapy.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"364 ","pages":"Article 123789"},"PeriodicalIF":10.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is it possible to completely dry cellulose? 有可能使纤维素完全干燥吗？

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-05-23 DOI: 10.1016/j.carbpol.2025.123803

Aleksandar Y. Mehandzhiyski , Maria-Ximena Ruiz-Caldas , Patrick Heasman , Varvara Apostolopoulou-Kalkavoura , Lennart Bergström , Igor Zozoulenko

{"title":"Is it possible to completely dry cellulose?","authors":"Aleksandar Y. Mehandzhiyski , Maria-Ximena Ruiz-Caldas , Patrick Heasman , Varvara Apostolopoulou-Kalkavoura , Lennart Bergström , Igor Zozoulenko","doi":"10.1016/j.carbpol.2025.123803","DOIUrl":"10.1016/j.carbpol.2025.123803","url":null,"abstract":"<div><div>Cellulose nanocrystals (CNCs) are widely used in advanced materials due to their unique mechanical and physicochemical properties. However, their interactions with water, particularly in the context of drying, remain poorly understood. The presence of bound water in CNC poses challenges for processing, storage, and applications sensitive to moisture. In this study, we combine molecular simulations and experimental drying investigations to assess the extent of water retention in both native and TEMPO-CNC under different thermodynamic conditions. Our results demonstrate that while native CNCs can be fully dried under low pressure (≤1 mbar) and elevated temperature (110 °C), TEMPO-CNC retain a significant amount of water (1–7 wt%) due to electrostatic interactions between water molecules and the charged surface carboxylic groups and the sodium counter-ions. These findings provide fundamental insights into the drying behavior of functionalized nanocellulose and highlight the importance of considering residual bound water in applications requiring moisture-sensitive performance.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"365 ","pages":"Article 123803"},"PeriodicalIF":10.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144170361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Self-healing waterborne polyurethane nanocomposites with high strength and toughness based on ureidopyrimidinone-modified cellulose nanocrystals 基于脲嘧啶修饰纤维素纳米晶体的高强度、高韧性自修复水性聚氨酯纳米复合材料

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-05-23 DOI: 10.1016/j.carbpol.2025.123806

Naishuo Yan , Xiuzhong Zhu , Li Tian , Jinbang Han , Jinjie Zang , Haitao Zhang

{"title":"Self-healing waterborne polyurethane nanocomposites with high strength and toughness based on ureidopyrimidinone-modified cellulose nanocrystals","authors":"Naishuo Yan , Xiuzhong Zhu , Li Tian , Jinbang Han , Jinjie Zang , Haitao Zhang","doi":"10.1016/j.carbpol.2025.123806","DOIUrl":"10.1016/j.carbpol.2025.123806","url":null,"abstract":"<div><div>Cellulose nanocrystals (CNCs), as a biomass resource, are mainly used as fillers to enhance the mechanical strength of materials. However, CNCs are prone to aggregation in an aqueous matrix due to their high hydroxyl group content. Nevertheless, preparing high-performance synthetic polymers or biopolymers to reinforce polymer nanocomposites is still a significant challenge. Herein, a strategy was developed to prepare high-performance waterborne polyurethane (WPU) nanocomposites via synergistic interaction of multiple hydrogen-bonded assemblies and disulfide bonding. First, 2-ureido-4-[1H]-pyrimidinone (UPy) motifs were grafted onto CNC to obtain UPy-CNC and alleviate the aggregation problem. Then, WPU nanocomposites containing aromatic and aliphatic disulfide bonds were reinforced by UPy-CNC. The tensile strength and toughness of the composites were tested. The tensile strength of the material reached 48.07 ± 2.45 MPa, and the toughness was as high as 142.72 ± 2.7 MJ m<sup>−3</sup>. Thus, these nanocomposites exhibited exceptional tensile strength as well as good elongation at break and self-healing properties. This simple and effective strategy to prepare WPU nanocomposites may have excellent application value in waterborne coatings.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"365 ","pages":"Article 123806"},"PeriodicalIF":10.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144170360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural characterization of intact polysaccharides by MALDI-in-source decay-Fourier transform ion cyclotron resonance (FTICR) MS maldi源内衰减-傅里叶变换离子回旋共振（FTICR）质谱法表征完整多糖的结构

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-05-23 DOI: 10.1016/j.carbpol.2025.123785

Yasmin van der Velden , Christoph Gstöttner , Constantin Blöchl , Leon Coulier , Adriana Carvalho de Souza , Elena Domínguez-Vega , Yuri van der Burgt , Manfred Wuhrer

{"title":"Structural characterization of intact polysaccharides by MALDI-in-source decay-Fourier transform ion cyclotron resonance (FTICR) MS","authors":"Yasmin van der Velden , Christoph Gstöttner , Constantin Blöchl , Leon Coulier , Adriana Carvalho de Souza , Elena Domínguez-Vega , Yuri van der Burgt , Manfred Wuhrer","doi":"10.1016/j.carbpol.2025.123785","DOIUrl":"10.1016/j.carbpol.2025.123785","url":null,"abstract":"<div><div>Polysaccharides occur throughout all kingdoms of life including plants, microorganisms and animals. They differ profoundly in structure and function ranging from heparin that serves as an anti-coagulant to pectins that are used to modify food properties. Mass spectrometry (MS) is a powerful technique for the characterization of polysaccharides and is often applied in conjunction with chemical or enzymatic degradation. Here, we show that wide mass range ultrahigh-resolution matrix-assisted laser desorption/ionization (MALDI) in-source decay (ISD) Fourier transform ion cyclotron resonance (FTICR) MS is suitable as a generic and robust method for the analysis of polysaccharides at the level of large fragments. We successfully analyzed polysaccharides that differ widely regarding composition and origin. The ISD fragment ions conferred information on monosaccharide composition as well as modifications including sulfation, amidation and methoxylation. Additionally, we could determine the pectins' degree of methoxylation from these ISD fragment ions. Performing MS<sup>2</sup> of the ISD fragments confirmed the proposed identity and provided additional structural characteristics. We conclude that MALDI-ISD-MS is a fast and robust method for the characterization of polysaccharides complementing other analytical techniques. Specifically, the method may be evaluated for a rapid determination of differences between polysaccharide variants and batches, for establishing structure-function relationships.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"364 ","pages":"Article 123785"},"PeriodicalIF":10.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144170774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural characterization and anticancer properties of a novel mushroom-derived rhamnogalactan in a triple-negative breast cancer model 一种新型蘑菇衍生鼠李糖半乳聚糖在三阴性乳腺癌模型中的结构表征和抗癌特性

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-05-23 DOI: 10.1016/j.carbpol.2025.123735

Eliane Leal de Lara , Matheus Zavadinack , Shayane da Silva Milhorini , Karin Maciel Wurzer , Giseli Klassen , Lucimara M.C. Cordeiro , Marcello Iacomini

{"title":"Structural characterization and anticancer properties of a novel mushroom-derived rhamnogalactan in a triple-negative breast cancer model","authors":"Eliane Leal de Lara , Matheus Zavadinack , Shayane da Silva Milhorini , Karin Maciel Wurzer , Giseli Klassen , Lucimara M.C. Cordeiro , Marcello Iacomini","doi":"10.1016/j.carbpol.2025.123735","DOIUrl":"10.1016/j.carbpol.2025.123735","url":null,"abstract":"<div><div>Mushroom-derived polysaccharides are known for their diverse biological activities, including immunomodulatory and anticancer properties. Breast cancer, the leading cause of cancer-related death among women worldwide, lacks targeted molecular therapies, underscoring the need for novel therapeutic agents. In this study, we extracted, purified, and characterized a novel heteropolysaccharide (HTP) - a rhamnogalactan - composed of galactose (72.6 %) and rhamnose (27.4 %) from the edible mushroom <em>Lactarius quieticolor</em>. Structural analysis revealed that HTP consists of a (1 → 6)-linked α-<span>d</span>-galactopyranose backbone, heavily substituted at <em>O</em>-2 by non-reducing rhamnose units, with a weight-average molar mass of 2.41 × 10<sup>4</sup> g.mol<sup>−1</sup>. <em>In vitro</em> assays using a triple-negative breast cancer (TNBC) cell model - the most aggressive subtype - showed a significant reduction in cell viability (50 % at 1200 μg·mL<sup>−1</sup>). Furthermore, an additive effect was observed when co-administered with the chemotherapy drug paclitaxel, reducing the cell viability to 42 %. These findings suggest potential therapeutic applications of the purified mushroom rhamnogalactan reported in this study against TNBC.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"364 ","pages":"Article 123735"},"PeriodicalIF":10.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144147958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances in polysaccharide-based edible films/coatings for food preservation: fabrication, characterization, and applications in packaging 食品保鲜用多糖可食性薄膜/涂层的研究进展：制备、表征及其在包装中的应用

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-05-22 DOI: 10.1016/j.carbpol.2025.123779

Yiting Fan , Jiahao Ren , Xinglong Xiao , Yifang Cao , Youning Zou , Bowen Qi , Xuying Luo , Fengsong Liu

{"title":"Recent advances in polysaccharide-based edible films/coatings for food preservation: fabrication, characterization, and applications in packaging","authors":"Yiting Fan , Jiahao Ren , Xinglong Xiao , Yifang Cao , Youning Zou , Bowen Qi , Xuying Luo , Fengsong Liu","doi":"10.1016/j.carbpol.2025.123779","DOIUrl":"10.1016/j.carbpol.2025.123779","url":null,"abstract":"<div><div>Fruits and vegetables are highly susceptible to spoilage and deterioration after harvest due to ongoing metabolic activities and, most critically, microbial contamination, resulting in substantial losses and waste. To address the increasing consumer demand for safe, eco-friendly, nutritious, and long-shelf-life foods, polysaccharide-based edible films and coatings have emerged as an innovative and sustainable solution for food packaging. This paper presents a comprehensive review of the preparation and manufacturing methods of polysaccharide-based edible films and coatings, highlighting their key characteristics and applications. It systematically examines their classification, recent advancements, and impacts on food quality. Particular attention is given to recent innovations in active packaging, modified packaging, and intelligent packaging technologies. The review also explores the limitations of polysaccharide-based edible films and coatings in the post-harvest preservation of fruits and vegetables, discusses the latest developments in this field, and outlines promising future research directions. By synthesizing these insights, this paper aims to assist researchers in the food and related industries, offering valuable perspectives on the development trends of polysaccharide-based edible film and coating technology for sustainable food packaging.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"364 ","pages":"Article 123779"},"PeriodicalIF":10.7,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144134938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced antifungal activity of chitosan-coated cinnamaldehyde-immobilized thermostable cellulose from spent mushroom substrate against phytopathogenic fungi 壳聚糖包被肉桂醛固定化热稳定型废蘑菇底物纤维素对植物病原菌的抗真菌活性增强

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-05-22 DOI: 10.1016/j.carbpol.2025.123790

Usman Rasheed , Bin Liu , Qurat Ul Ain , Ganhui Mo , Bin Shan , Kaikai Meng , Ganlin Chen

{"title":"Enhanced antifungal activity of chitosan-coated cinnamaldehyde-immobilized thermostable cellulose from spent mushroom substrate against phytopathogenic fungi","authors":"Usman Rasheed , Bin Liu , Qurat Ul Ain , Ganhui Mo , Bin Shan , Kaikai Meng , Ganlin Chen","doi":"10.1016/j.carbpol.2025.123790","DOIUrl":"10.1016/j.carbpol.2025.123790","url":null,"abstract":"<div><div>Phytopathogenic fungi jeopardize global food security, fueling reliance on synthetic fungicides with severe ecological impacts. Avoiding these chemicals risks a food crisis, highlighting the need for sustainable alternatives. Cinnamaldehyde (CA) is a natural but chemically unstable fungicide, hence requiring stabilization through effective immobilization. This study presents a biodegradable and sustainable alternative to synthetic anchoring materials: spent-mushroom-substrate-derived cellulose. CA immobilized cellulose was coated with chitosan which further enhanced the antifungal potential and contributed to slow release of CA. Cellulose extraction and CA encapsulation were successfully confirmed through analytical characterization. The resulting product (CeCACs) proved a promising fungicide, inhibiting key phytopathogenic fungi <em>Fusarium oxysporum</em>, <em>Aspergillus flavus</em>, and <em>Aspergillus niger</em> at 46. 8 μg/mL and <em>Fusarium solani</em> at 93.7 μg/mL concentration. The obtained minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) values were significantly lower than commercial fungicide, tebuconazole (TB). The fungicidal mechanism involved reactive oxygen species accumulation, plasma membrane damage, and apoptosis-like cell death. Using CeCACs as a peanut seed coating enhanced seedling growth and enriched beneficial endophytic bacteria, while CeCACs fumigation effectively eradicated <em>Fusarium oxysporum</em> from peanut and passion fruit surfaces. This study emphasizes converting agri-waste into a green fungicide, supporting sustainable and regenerative agriculture.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"364 ","pages":"Article 123790"},"PeriodicalIF":10.7,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144131452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0