Carbohydrate Polymers最新文献_第2页

The structural discrepancy between the ability of fructan and arabinogalactan to cure acute pharyngitis in Hosta plantaginea (Lam.) Aschers flowers

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-26 DOI: 10.1016/j.carbpol.2024.123059

Tiankai Bai , Shuguang Bao , Yuhui Li , Xiaorong Hou , Sirigunqiqige Pan , Huan Wang , Yuping Zhao , Matthew Liddle , Huifang Li , Laxinamujila Bai , Xiaohe Xiao

{"title":"The structural discrepancy between the ability of fructan and arabinogalactan to cure acute pharyngitis in Hosta plantaginea (Lam.) Aschers flowers","authors":"Tiankai Bai , Shuguang Bao , Yuhui Li , Xiaorong Hou , Sirigunqiqige Pan , Huan Wang , Yuping Zhao , Matthew Liddle , Huifang Li , Laxinamujila Bai , Xiaohe Xiao","doi":"10.1016/j.carbpol.2024.123059","DOIUrl":"10.1016/j.carbpol.2024.123059","url":null,"abstract":"<div><div>The flowers of <em>Hosta plantaginea</em> (Lam.), a traditional Chinese medicine, is utilized for the treatment of sore throat, aphonia, and cough alleviation. The polysaccharides HPFP-1 and HPFP-2 were separated from these plants through water-soluble alcohol precipitation and column chromatography. After structural analysis (monosaccharide composition, methylation and NMR), The →1)-β-D-Fru<em>f</em>-(2→ and →1,6)-β-D-Fru<em>f</em>-(2→, →6)-α-D-Glc<em>p</em> were interconnected to form the main chain of HPFP-1. The →3,6)-β-D-Gal<em>p</em>-(1→, →5)-α-L-Ara<em>f</em>-(1→, and →3)-β-D-Gal<em>p</em>-6-OMe(1→, →6)-β-D-Gal<em>p</em>-(1→, →4)-α-D-Gal<em>p</em>-(1→ were interconnected to form the main chain of HPFP-2. In acute pharyngitis rats, HPFP effectively increased the level of NO, decreased the levels of TNF-α, IL-1β, and IL-6, and reduced macrophage and neutrophil infiltration. In the LPS-induced RAW 264.7 cell model, HPFP-1 and HPFP-2 decreased the levels of NO, TNF-α, IL-6, p-p65, and p-IκB, which demonstrated the anti-inflammatory mechanism of these two polysaccharides through the inhibition of the NF-κB signaling pathway. Therefore, they have the potential to be highly effective drugs for combating acute pharyngitis.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"350 ","pages":"Article 123059"},"PeriodicalIF":10.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elucidation of the fine structure and anti–breast tumor activity of a glucomannan from the pseudobulbs of Pleione bulbocodioides

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-26 DOI: 10.1016/j.carbpol.2024.123062

Wan-Qi Deng, Shao-Wei Han, Si-Yuan Shao, Shuai Li

{"title":"Elucidation of the fine structure and anti–breast tumor activity of a glucomannan from the pseudobulbs of Pleione bulbocodioides","authors":"Wan-Qi Deng, Shao-Wei Han, Si-Yuan Shao, Shuai Li","doi":"10.1016/j.carbpol.2024.123062","DOIUrl":"10.1016/j.carbpol.2024.123062","url":null,"abstract":"<div><div>Pseudobulbs of <em>Pleione bulbocodioides</em> have been used as traditional Chinese medicine for a long time to treat cancers through decoction with water. However, as its main water-soluble ingredient, the structure of polysaccharide has not been elucidated yet. To obtain its polysaccharide with antitumor activity, a series of isolation, structural identification and antitumor evaluation experiments were performed. As a result, a newly discovered glucomannan, named PBP, was isolated and purified from the pseudobulbs of <em>P. bulbocodioides</em>. The molecular weight of PBP is 1.11 × 10<sup>5</sup> Da. Its monosaccharide composition comprises mannose and glucose at a molar ratio of 5:3. The fine structure of PBP was confirmed as a linear glucomannan backbone primarily comprising repeating →4)-β-<span>d</span>-Glc-(1 → 4)-β-<span>d</span>-Man-(1 → 4)-β-<span>d</span>-Glc-(1 → 4)-β-<span>d</span>-Man-(1 → 4)-β-<span>d</span>-Glc-(1 → 4)-β-<span>d</span>-Man-(1→4)-β-<span>d</span>-Man-(1 → 4)-β-<span>d</span>-Man-(1 → via a combination of analytical techniques and enzymolysis methods. PBP effectively inhibited the growth of 4T1 tumors with low toxicity in vivo<em>.</em> Furthermore, a noteworthy augmentation in the expression levels of CD4+ and CD8+ T cells suggested the existence of an elevated immune response. In summary, a new glucomannan with anti-breast tumor activity was obtained, which has the potential to contribute to breast cancer therapy.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"351 ","pages":"Article 123062"},"PeriodicalIF":10.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142746002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A β-cyclodextrin-based supramolecular photonic crystal hydrogel biosensor with macroporous structures for naked-eye visual detection of cholesterol

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-26 DOI: 10.1016/j.carbpol.2024.123068

Xi Wang , Jingjing Mu , Junjie Ren , Hairong Yu , Xingbin Lv , Ting Liang , Changjing Cheng

{"title":"A β-cyclodextrin-based supramolecular photonic crystal hydrogel biosensor with macroporous structures for naked-eye visual detection of cholesterol","authors":"Xi Wang , Jingjing Mu , Junjie Ren , Hairong Yu , Xingbin Lv , Ting Liang , Changjing Cheng","doi":"10.1016/j.carbpol.2024.123068","DOIUrl":"10.1016/j.carbpol.2024.123068","url":null,"abstract":"<div><div>Cholesterol (CHO) is an essential lipid in cell membranes and a precursor for vital living substances. Abnormal CHO levels can cause cardiovascular diseases. Therefore, simple and accurate monitoring of CHO levels is crucial for early diagnosis and effective management of cardiovascular diseases. Herein, we report a <em>β</em>-cyclodextrin-based supramolecular photonic crystal hydrogel (PCH) biosensor for naked-eye visual CHO detection. This sensor is composed of a poly(acrylamide-<em>co</em>-<em>N</em>-isopropylacrylamide-<em>co</em>-maleic anhydride-<em>β</em>-cyclodextrin) smart hydrogel with embedding Fe<sub>3</sub>O<sub>4</sub> colloidal chains, which can translate CHO concentration signals into visually detectable color changes of the hydrogel. By carefully selecting a macromolecular crosslinker, a macroporous structure of the hydrogel was achieved, significantly enhancing CHO responsiveness. Molecular docking provides detailed information about the binding mode between MAH-<em>β</em>-CD and CHO. The cyclohexanol portion and alkyl chain of CHO molecule are inserted into MAH-<em>β</em>-CD cavity, driven primarily by hydrophobic interactions. Moreover, this sensor demonstrates excellent regenerability and could be facilely regenerated by washing using hot/cold water or acid solution. Furthermore, it is highly selective for CHO and is suitable for detecting actual human serums. Such a <em>β</em>-CD-based supramolecular PCH biosensor with visualization, excellent regenerability, and high sensitivity and selectivity toward CHO, provides a basis for clinical diagnosis of diseases relative to CHO abnormalities.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"351 ","pages":"Article 123068"},"PeriodicalIF":10.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Astragalus polysaccharide/carboxymethyl chitosan/sodium alginate based electroconductive hydrogels for diabetic wound healing and muscle function assessment

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-26 DOI: 10.1016/j.carbpol.2024.123058

Letian Tang , Shuyang Xie , Danyang Wang , Yiying Wei , Xiaopu Ji , Yicheng Wang , Nana Zhao , Zonglei Mou , Baoping Li , Wan Ru Sun , Ping Yu Wang , Nicola Paccione Basmadji , José Luis Pedraz , Claudia Vairo , Eusebio Gainza Lafuente , Murugan Ramalingam , Xiaofei Xiao , Ranran Wang

{"title":"Astragalus polysaccharide/carboxymethyl chitosan/sodium alginate based electroconductive hydrogels for diabetic wound healing and muscle function assessment","authors":"Letian Tang , Shuyang Xie , Danyang Wang , Yiying Wei , Xiaopu Ji , Yicheng Wang , Nana Zhao , Zonglei Mou , Baoping Li , Wan Ru Sun , Ping Yu Wang , Nicola Paccione Basmadji , José Luis Pedraz , Claudia Vairo , Eusebio Gainza Lafuente , Murugan Ramalingam , Xiaofei Xiao , Ranran Wang","doi":"10.1016/j.carbpol.2024.123058","DOIUrl":"10.1016/j.carbpol.2024.123058","url":null,"abstract":"<div><div>Natural polysaccharides with excellent biocompatibility are considered ideal materials for repairing diabetic foot ulcer. However, diabetic foot ulcer is often accompanied by decreased muscle function, even resulting in muscle atrophy. During wound repair, monitoring muscle function at the wound site in real time can identify the decreased muscle strength timely, which is crucial for precise wound rehabilitation. Nevertheless, the majority of hydrogels are primarily utilized for wound healing and lack the capability for electromyography monitoring.</div><div>Here, we designed a multinetwork hydrogel composed of astragalus polysaccharide, chitosan, and sodium alginate and internally embedded conductive PPy-PDA-MnO<sub>2</sub> nanoparticles (P-NPs) loaded with resveratrol (Res) for wound repair and muscle function assessment. The intrinsic hypoglycemic and anti-inflammatory properties of astragalus polysaccharides, combined with the antioxidative and proangiogenic functions of Res, synergistically facilitate wound healing. The multinetwork structure affords the hydrogel excellent mechanical properties. Furthermore, the addition of conductive NPs not only improves the mechanical performance of the hydrogel but also confers electrical conductivity. The conductive hydrogel acts as an epidermal electrode which can be utilized for monitoring of electromyography signals. This novel approach for treating diabetic wounds ultimately achieves improved wound repair and muscle function assessment, carrying out a monitoring-guided safe and accurate wound repair.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"350 ","pages":"Article 123058"},"PeriodicalIF":10.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wheat starch-Lonicera caerulea berry polyphenols complex regulates blood glucose and improves intestinal flora in type 2 diabetic mice

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-26 DOI: 10.1016/j.carbpol.2024.123061

Suwen Liu , Fanna Meng , Ruonan Sun , Yue Li , Hanchen Li , Binghao Liu

{"title":"Wheat starch-Lonicera caerulea berry polyphenols complex regulates blood glucose and improves intestinal flora in type 2 diabetic mice","authors":"Suwen Liu , Fanna Meng , Ruonan Sun , Yue Li , Hanchen Li , Binghao Liu","doi":"10.1016/j.carbpol.2024.123061","DOIUrl":"10.1016/j.carbpol.2024.123061","url":null,"abstract":"<div><div>Resistant starch (RS) reduces or delays the digestion of carbohydrates and glucose synthesis, thereby lowering postprandial blood glucose levels. The wheat starch-<em>Lonicera caerulea</em> berry polyphenols (WS-LCBP) complex was constructed using high hydrostatic pressure (HHP). The effects of intragastric administration of WS or WS-LCBP on blood glucose in T2DM model mice. RS in the composite preparation formed by HHP and 10 % LCBP at 600 MPa for 30 min increased from 7.65 % to 49.66 %. WS–LCBP formed an A + <em>V</em>-type crystal structure of the polyhydroxyl non-inclusion complex, which hindered the digestion of WS into glucose. Compared with LCBP intake, which caused 8.3 % reduction in 2-h postprandial blood glucose (<em>p <</em> 0.05), Homeostatic model assessment for insulin resistance demonstrated a 35.3 % decrease (<em>p <</em> 0.001) with WS-LCBP administration. Western blotting demonstrated that exposure to WS-LCBP activated the GLP-1R/PI3K/AKT signaling pathway in the liver tissue of T2DM mice, reducing insulin resistance. Furthermore, the concentration of short-chain fatty acids was markedly elevated. The structure and abundance of the intestinal flora were enhanced. The WS-LCBP complex demonstrated a more pronounced improvement than LCBP supplementation alone. This study offers a novel perspective and theoretical foundation for the regulation of postprandial blood glucose levels by polyphenol starch-based food biomacromolecules and their potential applications in starchy foods.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"351 ","pages":"Article 123061"},"PeriodicalIF":10.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of glycoside hydrolase-mediated wheat arabinoxylan hydrolysate on gut microbiota and metabolite profiles

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-26 DOI: 10.1016/j.carbpol.2024.123064

Zhijie Huang , Xudong Yang , Mingxi Liu , Lijun Yin , Xin Jia

{"title":"Effect of glycoside hydrolase-mediated wheat arabinoxylan hydrolysate on gut microbiota and metabolite profiles","authors":"Zhijie Huang , Xudong Yang , Mingxi Liu , Lijun Yin , Xin Jia","doi":"10.1016/j.carbpol.2024.123064","DOIUrl":"10.1016/j.carbpol.2024.123064","url":null,"abstract":"<div><div>Cereal arabinoxylans (AX) are complex non-digestible polysaccharides and their molecular structural features significantly influence their degradation and metabolic behaviors within the body. This study focuses on investigating the impact of wheat AX hydrolysates produced by different glycoside hydrolases on the gut microbiota during colonic fermentation. Endo-1,4-β-xylanase (XYN) and arabinofuranosidase (ARF) were used to hydrolyze the xylan backbone and remove the arabinose side chains, respectively. The digestive and degradation fate was analyzed through <em>in vitro</em> simulated gastrointestinal digestion and colonic fermentation models. Results indicated that all hydrolase-treated groups exhibited different intestinal flora community structures, characterized by enhanced diversity and reduced richness of gut microbiota, along with differentially enriched bacterial taxa compared to native AX. The glycosidase-treated group showed greater advantages in promoting the growth of beneficial bacteria such as <em>Bacteroides</em>, <em>Ruminococcus</em>, and <em>Faecalibacterium</em> and produced higher levels of beneficial metabolites, mainly acetate, butyrate and caproate. Lower degrees of polymerization and side-chain substitution in AX enzymatic hydrolysate, along with higher levels of arabinoxylan-oligosaccharides (AXOS) exhibited the optimal promotion effects. However, certain gut bacteria such as <em>Prevotella</em> and <em>Bifidobacterium</em> prefer structurally intact long-chain AX. This study demonstrates that AX hydrolysates with different molecular characteristics, induced by specific hydrolases selectively influence distinct microbial consortia. Higher levels of short-chain unsubstituted XOS are more effective at promoting intestinal health and maintaining intestinal homeostasis.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"351 ","pages":"Article 123064"},"PeriodicalIF":10.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142759157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insight into distribution and composition of nonhuman N-Glycans in mammalian organs via MALDI-TOF and MALDI-MSI

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-26 DOI: 10.1016/j.carbpol.2024.123065

Rui-Rui Guo , Bram Heijs , Wen-Jun Wang , Manfred Wuhrer , Li Liu , Guinevere S.M. Lageveen-Kammeijer , Josef Voglmeir

{"title":"Insight into distribution and composition of nonhuman N-Glycans in mammalian organs via MALDI-TOF and MALDI-MSI","authors":"Rui-Rui Guo , Bram Heijs , Wen-Jun Wang , Manfred Wuhrer , Li Liu , Guinevere S.M. Lageveen-Kammeijer , Josef Voglmeir","doi":"10.1016/j.carbpol.2024.123065","DOIUrl":"10.1016/j.carbpol.2024.123065","url":null,"abstract":"<div><div>The major hurdle of xenotransplantation is the immune response triggered by human natural antibodies interacting with carbohydrate antigens on the transplanted animal organ. Specifically, terminal glycoprotein motifs such as galactose-α1,3-galactose (α-Gal) and <em>N</em>-glycolylneuraminic acid (Neu5Gc) are significant obstacles. Little is known about the abundance and compositions of asparagine-linked complex carbohydrates (<em>N</em>-glycans) carrying these motifs in mammalian organs. By studying heart, kidney, and liver tissues from pig, cattle, and sheep, we aimed to gain insights into the abundance and spatial distribution of α-Gal- or Neu5Gc-containing <em>N</em>-glycans. <em>N</em>-glycomes were analyzed using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), MALDI-mass spectrometry imaging (MSI), and capillary electrophoresis-electrospray ionization (CE-ESI)-MS. Both α-Gal- and Neu5Gc-containing <em>N</em>-glycans were present in all samples, with α-Gal-modified <em>N</em>-glycans being the most abundant nonhuman carbohydrate motif. The abundance of <em>N</em>-glycans terminating with α-Gal or Neu5Gc was higher in heart and kidney samples than livers. MSI revealed kidneys had the highest glycosylation levels, and α-Gal-containing <em>N</em>-glycans were abundant in the kidney cortex but scarce in the medulla. This study enhances our understanding of α-Gal- and Neu5Gc-modified <em>N</em>-glycans in animal organs and may guide research on carbohydrate antigen-induced immune rejection in xenotransplantation.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"351 ","pages":"Article 123065"},"PeriodicalIF":10.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rheological and thermal property of KH570-modified nano-SiO2 grafted xanthan gum and its application in drilling fluid system

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-26 DOI: 10.1016/j.carbpol.2024.123013

Jingqi Shi , Long Chen , Ruihan Xie , Jiayin Zhang , Shuangcheng Pi , Jiaming Yang , Yunhai Zhao , Feng Xiong , Yongkui Zhang , Tonghui Xie

{"title":"Rheological and thermal property of KH570-modified nano-SiO2 grafted xanthan gum and its application in drilling fluid system","authors":"Jingqi Shi , Long Chen , Ruihan Xie , Jiayin Zhang , Shuangcheng Pi , Jiaming Yang , Yunhai Zhao , Feng Xiong , Yongkui Zhang , Tonghui Xie","doi":"10.1016/j.carbpol.2024.123013","DOIUrl":"10.1016/j.carbpol.2024.123013","url":null,"abstract":"<div><div>Xanthan gum (XG), recognized for its environmentally friendly properties and versatile capabilities, has been studied for drilling fluid applications. However, its limited solubility and thermal stability restricts its broader use. In this study, a modified XG derivative, XG-g-KH570 modified SiO<sub>2</sub>, was synthesized by grafting XG with KH570-modified nano-SiO<sub>2</sub>. The modified product exhibited lower molecular weights with M<sub>n</sub> and M<sub>w</sub> of 3.00 × 10<sup>5</sup> g/mol and 3.77 × 10<sup>5</sup> g/mol, respectively. Its pyruvate and acetyl contents decreased to 2.72 % and 1.68 %, respectively. Meanwhile, XG-g-KH570 modified SiO<sub>2</sub> showed a higher branching degree of 45.3 % based on methylation analysis. In terms of performance, XG-g-KH570 modified SiO<sub>2</sub> exhibited improved water solubility. XG-g-KH570 modified SiO<sub>2</sub> demonstrated superior high-temperature and high-salinity performance, retaining high viscosity retention and viscoelasticity. Additionally, XG-g-KH570 modified SiO<sub>2</sub> exhibited a markedly reduced fluid loss of only 3.4 mL at 150 °C, compatible with conventional desulphonated drilling fluids. Furthermore, its high-temperature thickening and fluid loss control mechanisms was found to be associated with an enhanced cross-linked network structure based on the zeta potential and particle size distribution under high-temperature and salinity conditions. These results represent a promising advancement in the field of biomolecular drilling fluid additives, providing an efficient and eco-friendly solution for the oil and gas industry.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"351 ","pages":"Article 123013"},"PeriodicalIF":10.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Links between single maltodextrin particles properties and powder functionality

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-26 DOI: 10.1016/j.carbpol.2024.123057

Regis Badin , Claire Gaiani , Stephane Desobry , Sangeeta Prakash , Bhesh Bhandari , Ron Rasch , Heike Bostelmann , Jennifer Burgain

{"title":"Links between single maltodextrin particles properties and powder functionality","authors":"Regis Badin , Claire Gaiani , Stephane Desobry , Sangeeta Prakash , Bhesh Bhandari , Ron Rasch , Heike Bostelmann , Jennifer Burgain","doi":"10.1016/j.carbpol.2024.123057","DOIUrl":"10.1016/j.carbpol.2024.123057","url":null,"abstract":"<div><div>Maltodextrins are extensively used in the food industry to shape the physicochemical properties of food products. This multiscale study investigates three different Dextrose Equivalent (DE) maltodextrins as model matrices to elucidate the relationship between techno-functional behaviors and single particle surface properties. It was evidenced that environmental variations and glass transition influence single particle properties, significantly impacting the powder bulk behavior. Utilizing Confocal Laser Scanning Microscopy (CLSM) and environmental Atomic Force Microscopy (AFM) at the single particle level, correlations between the wetting and nanomechanical properties of all maltodextrins were provided. It was revealed that wetting properties are directly DE dependent, as higher DE maltodextrins had shorter wetting times. Moreover, glass transition plays a critical role in determining surface elasticity and capillary adhesion, as it alters both physicochemical properties and particle morphology. Indeed, a decrease of the Young modulus with Relative Humidity (RH) and glass transition correlated with the increase of capillary forces. This was corroborated by Scanning Electron Microscopy (SEM) and Specific Surface Area (SSA) measurements at different RH. These findings confirmed that glass transition drives particle morphology, with global surface smoothing and swelling occurring in the rubbery state.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"350 ","pages":"Article 123057"},"PeriodicalIF":10.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142746055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Versatile inulin/trans-ferulic acid/silk sericin nanoparticles-nourished probiotic complex with prolonged intestinal retention for synergistic therapy of inflammatory bowel disease

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-26 DOI: 10.1016/j.carbpol.2024.123063

Yujie Zhang , Xiaojiang Zhang , Lianxi Lv , Sheng Gao , Xiang Li , Ruochen Wang , Pengqian Wang , Feiyu Shi , Junjun She , Ya Wang

{"title":"Versatile inulin/trans-ferulic acid/silk sericin nanoparticles-nourished probiotic complex with prolonged intestinal retention for synergistic therapy of inflammatory bowel disease","authors":"Yujie Zhang , Xiaojiang Zhang , Lianxi Lv , Sheng Gao , Xiang Li , Ruochen Wang , Pengqian Wang , Feiyu Shi , Junjun She , Ya Wang","doi":"10.1016/j.carbpol.2024.123063","DOIUrl":"10.1016/j.carbpol.2024.123063","url":null,"abstract":"<div><div>To achieve effective long-term synergistic treatment of inflammatory bowel disease (IBD) with probiotics, we developed a versatile inulin/trans-ferulic acid/silk sericin nanoparticles-nourished probiotic complex. Inulin/TFA/SS nanoparticles were fabricated by inulin, trans-ferulic acid (TFA), and silk sericin (SS), and then loaded onto the surface of poly-<span>l</span>-lysine (PLL) and poly-glutamic acid (PGA)-coated <em>Bifidobacterium longum</em> (BL) to obtain BL@PLL-PGA-Inulin/TFA/SS NPs (BL@PP-NPs). This design simultaneously endowed the complex with excellent gastrointestinal resistance, antioxidant, and anti-inflammation abilities. Moreover, the inulin in the nanoparticles acts as a prebiotic, promoting the <em>Bifidobacterium's</em> rapid proliferation to exert effects within a short period. Compared with uncoated BL, BL@PP-NPs exhibited excellent gastric acid tolerance and up to 31.32-fold colonic colonization, and the ROS scavenging and proliferative capacity were increased by 5.61- and 1.39-fold, respectively. In a mouse model of dextran sulfate sodium (DSS)- and trinitrobenzene sulfonic acid (TNBS)-induced colitis, the components of Inulin/TFA/SS NPs synergized with probiotics to efficiently treat IBD by attenuating oxidative stress, decreasing inflammation, repairing intestinal barrier, and promoting the rapid proliferation of probiotics to reverse gut microbial disorders. Collectively, food-grade BL@PP-NPs represent a novel approach to probiotic modification that offers an effective, safe, and synergistic therapy for IBD.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"350 ","pages":"Article 123063"},"PeriodicalIF":10.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0