Carbohydrate Polymers最新文献_第3页

α2,6-linked sialylated oligosaccharides riched in goat milk alleviate food allergy by regulating the gut flora and mucin O-glycosylation 山羊奶中富含的α2,6-连接的糖基化低聚糖通过调节肠道菌群和粘蛋白 O-糖基化缓解食物过敏症

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-23 DOI: 10.1016/j.carbpol.2024.123049

Cheng Li , Tianjiao Han, Peiyun Zhong, Yuyang Zhang, Tong Zhao, Shukai Wang, Xiaoqin Wang, Yang Tian, Guiping Gong, Yuxia Liu, Linjuan Huang, Yu Lu, Zhongfu Wang

{"title":"α2,6-linked sialylated oligosaccharides riched in goat milk alleviate food allergy by regulating the gut flora and mucin O-glycosylation","authors":"Cheng Li , Tianjiao Han, Peiyun Zhong, Yuyang Zhang, Tong Zhao, Shukai Wang, Xiaoqin Wang, Yang Tian, Guiping Gong, Yuxia Liu, Linjuan Huang, Yu Lu, Zhongfu Wang","doi":"10.1016/j.carbpol.2024.123049","DOIUrl":"10.1016/j.carbpol.2024.123049","url":null,"abstract":"<div><div>The nutritious goat milk has low allergenicity. Oligosaccharides represent one of the crucial functional constituents in goat milk, which are structurally similar to human milk oligosaccharides (HMOs). Currently, the anti-allergic activity of GMOs has not been reported. In this study, GMOs were efficiently separated into neutral (NGMOs) and sialylated (SGMOs) fractions, following by qualitative and quantitative analysis at the isomer level using online LC-MS/MS. Fifteen NGMOs and 28 SGMOs were detected in goat milk, with 10 SGMOs reported for the first time. Distinctly, α2,6-linked SGMOs were 3.9 times more abundant in goat milk than in bovine milk, with the total relative content of 6′SL, 3′SLN and 6′NGL in SGMOs approach to 60%, which is more similar to HMOs. Orally administering GMOs, especially α2,6-linked sialylated oligosaccharides, significantly alleviated food allergy in ovalbumin-induced BALB/c mice. SGMOs restored the balance of <em>Lachnospiraceae</em>, <em>Erysipelotrichaceae</em>, and <em>Bacteroidaceae</em>, reconstructed the intestinal mucosal barrier, especially restored the levels of fucosylation, sialylation, and sulfation of mucin <em>O</em>-glycans, increased the expression of four core type 2 <em>O</em>-glycans (F1H2N2, F2H2N2, S1F2H2N2, and A1F1H2N2) significantly. This is the first comprehensive study of the anti-allergic activity of GMOs, and the results lay the foundation for the development of GMOs-based natural anti-allergic components.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"350 ","pages":"Article 123049"},"PeriodicalIF":10.7,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142719733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MWCNTs-Beta-Cyclodextrin-reduced graphene oxide gel based electrochemical sensor for simultaneous detection of dopamine and uric acid in human sweat samples

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-23 DOI: 10.1016/j.carbpol.2024.123060

Muthui Martin Mwaurah , Jayaraman Mathiyarasu , A.M. Vinu Mohan

{"title":"MWCNTs-Beta-Cyclodextrin-reduced graphene oxide gel based electrochemical sensor for simultaneous detection of dopamine and uric acid in human sweat samples","authors":"Muthui Martin Mwaurah , Jayaraman Mathiyarasu , A.M. Vinu Mohan","doi":"10.1016/j.carbpol.2024.123060","DOIUrl":"10.1016/j.carbpol.2024.123060","url":null,"abstract":"<div><div>Accurate determination of dopamine (DA) and uric acid (UA) in biological samples is crucial in diagnosing neurodegenerative disorders and gout, respectively. Here we report a highly sensitive and inexpensive, flexible screen-printed sensor for determining DA and UA in sweat samples. Beta-cyclodextrin-based (βCD) composite gel with reduced graphene oxide (rGO) was synthesized by self-polymerization of βCD at an optimum ratio of “good” and “poor solvent”. Multiwall carbon nanotubes (MWCNTs) were incorporated into the composite as a conductive filler. The MWCNTs-βCD-rGO gel provides selective biorecognition of DA and UA at the electrode surface through guest-host interaction. The gels were characterized by XRD, TGA, FTIR, UV–Vis, <sup>1</sup>H NMR, FESEM, XPS and optical microscopy. The flexible printed sensor showed linear DA detection in the range 0.25 to 16 μM with a correlation coefficient (R<sup>2</sup>) of 0.9890, limit of detection (LoD) of 0.08 μM and sensitivity of 3.63 μA μM<sup>−1</sup> cm<sup>−2</sup>. Similarly, UA calibration showed linear detection from 50 to 700 μM with a R<sup>2</sup> value of 0.9860, LoD of 0.078 μM and sensitivity of 0.118 μA μM<sup>−1</sup> cm<sup>−2</sup>. The SPE/MWCNTs-βCD-rGOsensor showed simultaneous determination of DA and UA from exercise induced sweat samples. The proposed sensor demonstrated excellent repeatability and satisfactory recoveries in human sweat.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"350 ","pages":"Article 123060"},"PeriodicalIF":10.7,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142746054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, (bio)degradation, and utilization of starch-derived biopolymers in defined hard waters

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-23 DOI: 10.1016/j.carbpol.2024.123047

Adrián Matencio , David Rupérez-Cebolla , Edoardo Fioravanti , Daniele dalla Pria , Claudio Cecone , Filomena Silva , Francesco Trotta

{"title":"Synthesis, (bio)degradation, and utilization of starch-derived biopolymers in defined hard waters","authors":"Adrián Matencio , David Rupérez-Cebolla , Edoardo Fioravanti , Daniele dalla Pria , Claudio Cecone , Filomena Silva , Francesco Trotta","doi":"10.1016/j.carbpol.2024.123047","DOIUrl":"10.1016/j.carbpol.2024.123047","url":null,"abstract":"<div><div>Climate change is causing a change in local rainfall, which generally brings with it a reduction in rainfall and, consequently, an increase in water hardness. This study explores the suitability and stability of various dextrin-derived polymers for cation removal in simulated hard water conditions. Thermal analysis and Fourier-transform infrared spectroscopy confirm the polymers' thermal stability and proper formation. Biodegradability assessments reveal KLEPTOSE®LINECAPS (LC) and GLUCIDEX2® (Glu2) dextrin with pyromellitic dianhydride (PMDA) derivatives have higher durability as they were able to endure enzymatic activity. Adsorption experiments at 300 and 600 ppm indicate significant variations influenced by monomer and crosslinker types, with linear monomers demonstrating superior performance. Notably, different crosslinkers exhibit varying affinities for calcium and magnesium ions, with PMDA derivatives excelling for magnesium and citric acid (CA) derivatives for calcium. Kinetic and isotherm studies reveal a favorable trend towards quasi-second-order kinetics and Freundlich isotherm models, attributed to cavity heterogeneity and diverse attachment points as evidenced in existing literature. These findings suggest promising applications for these polymers, traditionally employed for organic contaminant removal, as additional filters to mitigate water hardness.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"350 ","pages":"Article 123047"},"PeriodicalIF":10.7,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New insights into rice starch-gallic acid-whey protein isolate interactions: Effects of multiscale structural evolution and enzyme activity on starch digestibility

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-22 DOI: 10.1016/j.carbpol.2024.123039

Ran Meng, Ran Feng, Si-Jie Wu, Qiu-Ya Ji, Han Tao, Bao-Cai Xu, Bao Zhang

{"title":"New insights into rice starch-gallic acid-whey protein isolate interactions: Effects of multiscale structural evolution and enzyme activity on starch digestibility","authors":"Ran Meng, Ran Feng, Si-Jie Wu, Qiu-Ya Ji, Han Tao, Bao-Cai Xu, Bao Zhang","doi":"10.1016/j.carbpol.2024.123039","DOIUrl":"10.1016/j.carbpol.2024.123039","url":null,"abstract":"<div><div>In starch-based food where proteins and polyphenols coexist, the impact of protein on the inhibition of starch digestion by polyphenols is unclear. Therefore, the aim of this study was to investigate the impact of whey protein isolate (WPI) on the inhibition of rice starch digestion by gallic acid (GA) from the aspects of multiscale structure and enzyme activity. Rice starch-gallic acid-whey protein isolate complex (RS-GA-WPI) was formed predominantly by hydrogen bonding and hydrophobic interactions. Compared to rice starch-gallic acid complex (RS-GA), RS-GA-WPI exhibited higher short-range ordering and thermal stability, and lower relative crystallinity. Fluorescence spectra and molecular docking showed that the interactions between GA and WPI weakened the hydrogen bond between GA and enzyme active site, so that WPI significantly reduced the enzyme inhibitory activity of GA. The above factors led to the result that the presence of WPI weakened the inhibitory effect of GA on starch digestibility. RS-GA-WPI showed higher starch digestibility and lower resistant starch content compared to RS-GA. This study provided a new understanding of starch digestion mechanism in starch-polyphenol-protein coexistence system.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"350 ","pages":"Article 123039"},"PeriodicalIF":10.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142746056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antifreeze proteins and surface-modified cellulose nanocrystals for designing anti-freezing conductive hydrogel sensors

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-22 DOI: 10.1016/j.carbpol.2024.123056

Liangjiu Bai , Chenglin Yang , Xin Sun , Dongqi Yue , Wenxiang Wang , Hou Chen , Huawei Yang , Lixia Yang

{"title":"Antifreeze proteins and surface-modified cellulose nanocrystals for designing anti-freezing conductive hydrogel sensors","authors":"Liangjiu Bai , Chenglin Yang , Xin Sun , Dongqi Yue , Wenxiang Wang , Hou Chen , Huawei Yang , Lixia Yang","doi":"10.1016/j.carbpol.2024.123056","DOIUrl":"10.1016/j.carbpol.2024.123056","url":null,"abstract":"<div><div>Antifreeze proteins (AFPs) are a type of protein capable of inhibiting ice crystal growth, lowering the freezing point, and protecting organisms from cold-induced damage. In this study, cellulose nanocrystals (CNCs) are chemically modified to enhance the hydrogel's performance. The synergistic effect with AFPs further regulates its mechanical properties, antifreeze performance, and high sensing sensitivity. First, based on the principles of mussel-inspired chemistry, dopamine (DA) was introduced to increase adhesion and chemical crosslinking points, successfully modifying zwitterionic proline (ZP) onto the CNCs surface to obtain cellulose nanocrystals@polydopamine@zwitterionic proline (CNCs@PDA@ZP). Subsequently, CNCs@PDA@ZP and AFPs were incorporated into a multi-component network of polyacrylic acid/guar gum (PAA/GG) and FeCl<sub>3</sub> to construct an antifreeze, self-healing nanocomposite hydrogel-based flexible sensor. Through the synergistic effect of its components, along with AFPs inhibiting ice crystal growth by binding to H<sub>2</sub>O, the hydrogel achieves an 81.7 % self-healing rate in 1.3 h at −20 °C and a fracture stress of 3.0 MPa. Additionally, the hydrogel's high sensitivity (GF = 4.0) enhances its suitability for motion detection in flexible sensors. This work provides a method for modifying nanomaterials and contributes an approach for antifreeze, self-healing nanocomposite hydrogels.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"350 ","pages":"Article 123056"},"PeriodicalIF":10.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insight into the structural, interfacial and functional properties of soybean 11S globulin-debranched starch conjugates through alkaline Maillard reaction 通过碱性马氏反应深入了解大豆 11S 球蛋白-脱颗粒淀粉共轭物的结构、界面和功能特性

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-22 DOI: 10.1016/j.carbpol.2024.123054

Zhen Yang , Yuanyang Song , Liang Chen , Weimin Zhang , Dan Xie , Lianzhou Jiang , Zhaoxian Huang , Dongze Li

{"title":"Insight into the structural, interfacial and functional properties of soybean 11S globulin-debranched starch conjugates through alkaline Maillard reaction","authors":"Zhen Yang , Yuanyang Song , Liang Chen , Weimin Zhang , Dan Xie , Lianzhou Jiang , Zhaoxian Huang , Dongze Li","doi":"10.1016/j.carbpol.2024.123054","DOIUrl":"10.1016/j.carbpol.2024.123054","url":null,"abstract":"<div><div>This study examined the effects of the alkaline Maillard reaction on the structural, interfacial, and functional properties of soybean 11S globulin-debranched starch (DBS) conjugates. The results showed that the degree of DBS binding to 11S globulin was influenced by the polymer ratios, which in turn affected the structural, interfacial, and functional characteristics. The 11S-DBS conjugates with a 2:1 biopolymer ratio exhibited the highest grafting degree, largest zeta potential absolute value, smallest particle size, and greatest thermal stability. Conjugates with higher globulin content demonstrated superior interfacial and functional properties, including improved solubility, increased surface hydrophobicity, and reduced interfacial tension. 3D fluorescence scanning revealed a decrease in the signal of aromatic amino acid residues, while microstructural observation provided insights into the binding behavior of different 11S-DBS conjugates. Molecular docking simulations highlighted the key role of hydrogen bonding in the formation of these conjugates. This study enhances understanding of soybean globulin-polysaccharide interaction mechanisms, expanding their potential applications in the food, medical, and bioengineering industries.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"350 ","pages":"Article 123054"},"PeriodicalIF":10.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142719731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The formation and performance tuning mechanism of starch-based hydrogels 淀粉基水凝胶的形成与性能调整机制

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-22 DOI: 10.1016/j.carbpol.2024.123048

Jin Zhang , Zihan Liu , Jingxuan Sun , Zhuojun Yao , Hao Lu

{"title":"The formation and performance tuning mechanism of starch-based hydrogels","authors":"Jin Zhang , Zihan Liu , Jingxuan Sun , Zhuojun Yao , Hao Lu","doi":"10.1016/j.carbpol.2024.123048","DOIUrl":"10.1016/j.carbpol.2024.123048","url":null,"abstract":"<div><div>Starch-based hydrogels, characterized by their three-dimensional network structures, are increasingly explored for their biodegradability, low cost, and abundance of modifiable hydroxyl groups. However, a comprehensive understanding of the mechanisms behind the formation and property modulation of these hydrogels has not been systematically described. Drawing from literature of the past decade, this review provides insights into designing multifunctional starch-based hydrogels through various gelation mechanism, crosslinking strategies, and second-network structure. This comprehensive review aims to establish a theoretical framework for controlling the properties of starch-based hydrogels. A crucial aspect of starch hydrogel formation is the dense, cellular structure produced by swollen particles; when these particles fully disrupt, amylose recrystallization creates “junction zones” essential for network stability. In double-network hydrogels, materials such as polyvinyl alcohol (PVA), sodium alginate (SA), and polyacrylamide (PAM) form an effective secondary network, enhancing the mechanical strength and versatility of the hydrogel. The functionalization of starch-based hydrogels is primarily achieved through the introduction of functional group, secondary networks, and ionic liquids.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"350 ","pages":"Article 123048"},"PeriodicalIF":10.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142719734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fine structure of starch biomacromolecules and digestibility: The regulative role of amylose and amylopectin in the digestive hydrolysis of starch in rice

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-22 DOI: 10.1016/j.carbpol.2024.123040

Xianglong Zhou , Yitao Chen , Puxu Feng , Jinqi Shen , Xiaolei Fan , Yuan Chen , Wenwen Yu

{"title":"Fine structure of starch biomacromolecules and digestibility: The regulative role of amylose and amylopectin in the digestive hydrolysis of starch in rice","authors":"Xianglong Zhou , Yitao Chen , Puxu Feng , Jinqi Shen , Xiaolei Fan , Yuan Chen , Wenwen Yu","doi":"10.1016/j.carbpol.2024.123040","DOIUrl":"10.1016/j.carbpol.2024.123040","url":null,"abstract":"<div><div>The digestibility of starch in staple foods has rarely been examined at the bio-macromolecular level. This study addresses this by investigating the fine structures of amylose and amylopectin to understand their roles in starch digestibility in cooked white rice. Using the static INFOGEST protocol and oral processing by human volunteers, we assessed the starch digestion characteristics of 13 rice varieties, with amylose and amylopectin chain length distribution being analyzed using size-exclusion chromatography and high-performance anion exchange chromatography, respectively. Kinetic modelling revealed that chewed white rice follows a typical parallel digestion pattern, with rapidly (<span><math><msub><mi>S</mi><mi>F</mi></msub><mo>)</mo></math></span> and slowly digestible starch (<span><math><msub><mi>S</mi><mi>S</mi></msub></math></span>) being digested simultaneously at distinctly different rates. Amylose content (AC) and amylose weight were significantly and positively correlated with the digestion rate and extent of <span><math><msub><mi>S</mi><mi>S</mi></msub></math></span>, whereas the digestion rate and extent of <span><math><msub><mi>S</mi><mi>F</mi></msub></math></span> were closely linked to amylopectin, particularly its short and intermediate chains (degree of polymerization 13–36). Compared to low-amylose rice (AC < 25 %), high-amylose rice exhibited significantly higher <span><math><msub><mi>S</mi><mi>S</mi></msub></math></span> but with a lower digestion rate, attributed to its higher AC with shorter chains and fewer short to intermediate Ap branches. These findings provide insights into starch structure-digestibility relationships, aiding the development of rice varieties with slower digestion rates.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"350 ","pages":"Article 123040"},"PeriodicalIF":10.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Construction of a non-toxic interpenetrating network hydrogel drug carrier supported by carbon microspheres and nanocellulose

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-22 DOI: 10.1016/j.carbpol.2024.123035

Yanan Wang , Ying Zhang , Hao Zhong , Minghui Guo , Xueqi Chen , Yanan Lu

{"title":"Construction of a non-toxic interpenetrating network hydrogel drug carrier supported by carbon microspheres and nanocellulose","authors":"Yanan Wang , Ying Zhang , Hao Zhong , Minghui Guo , Xueqi Chen , Yanan Lu","doi":"10.1016/j.carbpol.2024.123035","DOIUrl":"10.1016/j.carbpol.2024.123035","url":null,"abstract":"<div><div>To develop a stable hydrogel drug carrier with excellent biocompatibility, biodegradability and low toxicity, a green biomass-based hydrogel was prepared as a methylene blue (MB) drug carrier model using cellulose and sodium alginate (SA) polysaccharide. The addition of nanocellulose (CNF) and hydrothermally prepared carbon microspheres to the hydrogel network formed by SA undergoing chelation with Ca<sup>2+</sup> enhanced the multifaceted properties of the drug carrier. Additionally, the prepared SA-CNFgel<sub>CS0.1</sub> could withstand a pressure of 8.64 N and showed good compressive and elastic properties. Meanwhile, its encapsulation rate and drug loading capacity could reach 95.5 % and 19.36 mg/g, respectively. The drug release rate reached 43.4 % at 100 h in PBS solution simulating the pH value of the gastric environment, indicating good pH-responsiveness and long-lasting release ability during the drug-carrying release process. The release mechanism of the drug carrier to MB was investigated by different release kinetic models, which was in accordance with the first-order kinetic model. SA-CNFgel<sub>CS0.1</sub> at high concentration also did not affect the number of pancreatic cell survival and showed a high degree of biocompatibility. In addition to that, SA-CNFgel<sub>CS0.1</sub> can reach 100 % degradation rate in 18 days, which has no burden on the environment during use. The present study offers a novel approach to the synthesis of a biomass drug-carrying model with enhanced performance. Furthermore, this drug carrier provides a promising foundation for the development of oral MB as a potential treatment for gastrointestinal diseases and other chronic condition.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"350 ","pages":"Article 123035"},"PeriodicalIF":10.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanocellulose-based functional materials towards water treatment 基于纳米纤维素的水处理功能材料

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-22 DOI: 10.1016/j.carbpol.2024.122977

Xiaohui Jiao , Keli Jia , Yajing Yu , Danyu Liu , Jingli Zhang , Kai Zhang , Huanda Zheng , Xiaohang Sun , Yingjia Tong , Qufu Wei , Pengfei Lv

{"title":"Nanocellulose-based functional materials towards water treatment","authors":"Xiaohui Jiao , Keli Jia , Yajing Yu , Danyu Liu , Jingli Zhang , Kai Zhang , Huanda Zheng , Xiaohang Sun , Yingjia Tong , Qufu Wei , Pengfei Lv","doi":"10.1016/j.carbpol.2024.122977","DOIUrl":"10.1016/j.carbpol.2024.122977","url":null,"abstract":"<div><div>Water resources are important ecological resources for human survival. To date, advanced water purification technology has become one of the focus of global attention due to the continuous deterioration of the environment and the serious shortage of freshwater resources. Recently, nanocellulose, as a kind of sustainable and carbon-neutral biopolymer, has not only the properties of cellulose, but also the important nature of nanomaterials, including large specific surface area, tailorable surface chemistry, excellent mechanical flexibility, biodegradability, and environmental compatibility. Herein, this review covers several methods of extraction and preparation of nanocellulose and the functional modification strategies. Subsequently, we systematically review the application and latest research progress of nanocellulose-based functional material towards water treatment, from micro/nanoparticles filtration, dyes/organics adsorption/degradation, heavy metal ions adsorption/detection and oil-water separation to seawater desalination. Furthermore, scalable and low-cost nanocellulose synthesis strategies are discussed. Finally, the challenges and opportunities of nanocellulose water purification substrate in industrial application and emerging directions are briefly discussed. This review is expected to provide new insights for the application of advanced functional materials based on nanocellulose in water treatment and environmental remediation, and promote rapid cross-disciplinary development.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"350 ","pages":"Article 122977"},"PeriodicalIF":10.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142719730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0