Carbohydrate Polymers最新文献_第10页

Corrigendum to “Chitosan/rutin multifunctional hydrogel with tunable adhesion, anti-inflammatory and antibacterial properties for skin wound healing” [Carbohydr. Polym. 343 (2024) 122492 用于皮肤伤口愈合的具有可调粘附性、消炎和抗菌特性的壳聚糖/芦丁多功能水凝胶" [Carbohydr.Polym.343 (2024) 122492

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-10-15 DOI: 10.1016/j.carbpol.2024.122844

Ran An, Chenyu Shi, Yan Tang, Zan Cui, Yinping Li, Zhiyong Chen, Min Xiao, Li Xu

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Co-delivery of antimicrobial peptide and Prussian blue nanoparticles by chitosan/polyvinyl alcohol hydrogels 壳聚糖/聚乙烯醇水凝胶联合递送抗菌肽和普鲁士蓝纳米颗粒

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-10-14 DOI: 10.1016/j.carbpol.2024.122873

Zhiyi Liao , Jiayi Li , Wenqiang Ni , Rixing Zhan , Xisheng Xu

{"title":"Co-delivery of antimicrobial peptide and Prussian blue nanoparticles by chitosan/polyvinyl alcohol hydrogels","authors":"Zhiyi Liao , Jiayi Li , Wenqiang Ni , Rixing Zhan , Xisheng Xu","doi":"10.1016/j.carbpol.2024.122873","DOIUrl":"10.1016/j.carbpol.2024.122873","url":null,"abstract":"<div><div>Altered skin integrity increases the chance of infection, and bacterial infections often lead to a persistent inflammatory response that prolongs healing time. Functional artificial hydrogels are receiving increasing attention as suitable wound dressing barrier. However, the antimicrobial effect of the new dressing still needs to be explored in depth. In this work, the antimicrobial peptide MSI-1 was covalently attached to chitosan-modified poly (vinyl alcohol) hydrogels mixed with Prussian blue nanoparticles (PBNPs) via a primary amine group coupled to a carboxyl group. The synthesized hydrogel has a long-lasting antimicrobial surface and is able to maintain its bactericidal effect on <em>Staphylococcus aureus</em> and <em>Escherichia coli</em> for 24 h. Due to the presence of PBNPs, the hydrogel was able to rise to 48.3 °C within 10 min under near infrared (NIR) light irradiation at a wavelength of 808 nm and maintain this mild temperature to avoid bacterial biofilms. The hydrogel showed >90 % survival in co-culture with cells for 3 d and did not damage major organs in animal experiments. Thus, the photothermal dual-mode antimicrobial hydrogel synthesized in this study increases the selectivity as a safe and efficient wound dressing for the treatment of infected skin defects.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"348 ","pages":"Article 122873"},"PeriodicalIF":10.7,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142539079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Bionic cell wall models: Utilizing TEMPO-oxidized cellulose nanofibers for fucoxanthin delivery systems 仿生细胞壁模型：将 TEMPO 氧化纤维素纳米纤维用于岩藻黄质输送系统

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-10-14 DOI: 10.1016/j.carbpol.2024.122850

Fang Tian , Shuyi Xu , Miaoyu Gan , Baihui Chen , Qian Luan , Luyun Cai

引用次数: 0

Carboxymethyl chitosan-enhanced multi-level microstructured composite hydrogel scaffolds for bone defect repair 用于骨缺损修复的羧甲基壳聚糖增强型多层次微结构复合水凝胶支架

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-10-14 DOI: 10.1016/j.carbpol.2024.122847

Yilong Wang , Xingyu Zhou , Junhui Jiang , Tianhao Zhao , Junbo Dang , Ruibo Hu , Chen Shen , Qiaochu Fan , Dahui Sun , Mei Zhang

{"title":"Carboxymethyl chitosan-enhanced multi-level microstructured composite hydrogel scaffolds for bone defect repair","authors":"Yilong Wang , Xingyu Zhou , Junhui Jiang , Tianhao Zhao , Junbo Dang , Ruibo Hu , Chen Shen , Qiaochu Fan , Dahui Sun , Mei Zhang","doi":"10.1016/j.carbpol.2024.122847","DOIUrl":"10.1016/j.carbpol.2024.122847","url":null,"abstract":"<div><div>Critical-sized bone defects (CSBDs) necessitate interventions like bone grafts or tissue engineering scaffolds to surpass the body's limited spontaneous healing capacity and ensure effective bone regeneration. A multi-level microstructured composite hydrogel 3D scaffold was fabricated for enhanced bone defect repair, integrating a 3D-printed macroporous polylactic acid (PLA) scaffold with polydopamine treatment and filled with a sodium alginate/nano hydroxyapatite/carboxymethyl chitosan (SA/nHA/CMCS) micrometer-scale porous composite hydrogel. The incorporation of nano hydroxyapatite (nHA) nanoparticles enhanced hydrogel crosslinking and osteogenic activity. A systematic evaluation of CMCS concentration demonstrated its pivotal role in enhancing hydrogel cross-linking and mineralization, regulating degradation rate adapted to the osteogenic cycle, endowing the scaffold with a bioactive micrometer-scale porous structure. <em>In vitro</em> studies confirmed the osteogenic effectiveness of the composite hydrogel 3D scaffold, particularly those with CMCS, which boosted bone mesenchymal stem cells (BMSCs) adhesion, proliferation, and differentiation. The rabbit tibial bone defect model further confirmed that, compared to the DAPLA (dopamine modified PLA) scaffold, the bone trabecular number of the DSHC (DAPLA-SA/nHA/CMCS) scaffold increases 2.06-fold. In conclusion, this study expanded the application of hydrogel scaffolds in bone tissue engineering and provided an effective strategy for the development of hydrogel implant materials.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"348 ","pages":"Article 122847"},"PeriodicalIF":10.7,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Preparation of nanocellulose-silk fibroin stiff hydrogel and high absorbing-low expansion xerogel via polysaccharide-protein interactions 通过多糖-蛋白质相互作用制备纳米纤维素-蚕丝纤维素硬水凝胶和高吸收低膨胀异凝胶

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-10-13 DOI: 10.1016/j.carbpol.2024.122867

Yue Ma , Tian Huang , Zhixing Hu , Juan Yu , Liang Liu , Lin Lin , Meijuan Chen , Ruoxian Jia , Xin Li , Zhiguo Wang , Yimin Fan

{"title":"Preparation of nanocellulose-silk fibroin stiff hydrogel and high absorbing-low expansion xerogel via polysaccharide-protein interactions","authors":"Yue Ma , Tian Huang , Zhixing Hu , Juan Yu , Liang Liu , Lin Lin , Meijuan Chen , Ruoxian Jia , Xin Li , Zhiguo Wang , Yimin Fan","doi":"10.1016/j.carbpol.2024.122867","DOIUrl":"10.1016/j.carbpol.2024.122867","url":null,"abstract":"<div><div>Inspired by the unique environmental sensitivities of polysaccharides and proteins, nanocellulose (NC) and silk fibroin (SF) nanocomposite hydrogels with tailored network structures and mechanical properties were developed by varying induction methods and assembly sequences. In the optimal process, SF was first assembled along the NC template to create a unique nanobead-like structure under thermal induction, followed by crosslinking in an acetic acid coagulation bath to form a polysaccharide-protein nanocomposite hydrogel with high mechanical strength, with elastic modulus as of 62,330 G′ in Pa at only 0.25 wt% NC and 1.5 wt% SF. The introduction of carboxyl groups to NC <em>via</em> TEMPO-mediated oxidation and the formation of nanobead-like structures improved structure stability and significantly enhanced water retention. The NC-SF nanocomposite hydrogels exhibited excellent mechanical properties, while the derived xerogels offered outstanding liquid absorption (up to 2300 %) and retention with minimal volume expansion upon liquid binding (dissolution ratio below 5 %). These properties make them promising candidates for biodegradable, biocompatible materials in applications such as sanitary products, diapers, and hemostatic matrices.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"348 ","pages":"Article 122867"},"PeriodicalIF":10.7,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Structural characterization of arabinogalactan-II and pectin from Urtica cannabina 大麻荨麻中阿拉伯半乳聚糖-II 和果胶的结构特征

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-10-13 DOI: 10.1016/j.carbpol.2024.122868

Victoria V. Golovchenko , Victor A. Khlopin , Olga A. Patova , Fedor V. Vityazev , Andrey S. Dmitrenok , Alexander S. Shashkov

{"title":"Structural characterization of arabinogalactan-II and pectin from Urtica cannabina","authors":"Victoria V. Golovchenko , Victor A. Khlopin , Olga A. Patova , Fedor V. Vityazev , Andrey S. Dmitrenok , Alexander S. Shashkov","doi":"10.1016/j.carbpol.2024.122868","DOIUrl":"10.1016/j.carbpol.2024.122868","url":null,"abstract":"<div><div>Comparative analysis of extracellular and cell wall glycans from <em>Urtica cannabina</em> leaves was performed using chemical methods, GC, GC–MS, 1D, and 2D NMR spectroscopy. The structures of extracellular AG-II and cell wall AG-II are similar. The units are typical for AG-IIs: β-Glc<em>p</em>A-4-OMe-(1→, Rha<em>p</em>-(1 → 4)-β-Glc<em>p</em>A-(1→, attached to β-Gal<em>p</em> at <em>O</em>-6, as well as arabinan chains attached to β-Gal<em>p</em> at <em>O</em>-3. A single Ara<em>f</em> and a trisaccharide formed by 2,5-Ara<em>f</em> and two terminal Ara<em>f</em> form short arabinan side chains in AG-II. 1,5-arabinan with a backbone substituted by a single Ara<em>f</em> at <em>O</em>-3 was identified only in the side chains of cell wall AG-II. The side chains can be attached to <em>O</em>-3 and <em>O</em>-6 of the same β-Gal<em>p</em> to form a bifurcated AG side chain. The backbone of AG-II is formed by 1,6- rather than 1,3-linked Gal<em>p</em>, although it does include some 1,3-Gal<em>p</em>. The high content of 3,6-Gal<em>p</em> shows the highly branched nature of the AG carbohydrate chains. From the cell wall, AGP was extracted together with pectin, the simultaneous elution of which from both DEAE-cellulose and Sepharose may indicate a link between them.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"348 ","pages":"Article 122868"},"PeriodicalIF":10.7,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Blending pectin and κ-carrageenan converted the liquid yogurt induced by pectin into the solid yogurt 果胶和κ-卡拉胶混合后，果胶诱导的液态酸奶变成了固态酸奶

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-10-13 DOI: 10.1016/j.carbpol.2024.122869

Hongkai Zhang , H. Douglas Goff , Chengmei Liu , Shunjing Luo , Xiuting Hu

{"title":"Blending pectin and κ-carrageenan converted the liquid yogurt induced by pectin into the solid yogurt","authors":"Hongkai Zhang , H. Douglas Goff , Chengmei Liu , Shunjing Luo , Xiuting Hu","doi":"10.1016/j.carbpol.2024.122869","DOIUrl":"10.1016/j.carbpol.2024.122869","url":null,"abstract":"<div><div>Effects of 0.11 %–0.17 % pectin and the mixture of 0.03 % κ-carrageenan and 0.11 %–0.17 % pectin on texture and microstructure of yogurt were investigated in this work. Rheology analysis demonstrated that adding 0.11 %–0.17 % pectin before fermentation inhibited gelation of yogurt and liquid yogurt was formed. However, when the above κ-carrageenan/pectin mixture was added, yogurt was gelled and solid-like. It was demonstrated by CLSM that milk protein aggregated into separated particles in the liquid yogurt induced by pectin, while milk protein aggregated into a continuous network in the solid yogurt induced by the mixture. Adding 0.11 %–0.17 % pectin into the casein micelle suspension induced aggregation of casein micelles into separated particles, which was the same in the corresponding liquid yogurt samples. Moreover, casein micelles precipitated in the pectin/casein micelle mixtures after storage for 3 h. However, when the above mixture was added into the casein micelle suspension, tightly-connected casein micelle aggregates appeared and the resultant κ-carrageenan/pectin/casein micelle mixtures were stable after storage for 3 h. These results indicated that the pectin-casein micelle interaction played an essential role in formation of the liquid yogurt and κ-carrageenan altered this interaction. Thus, blending κ-carrageenan and pectin converted the liquid yogurt induced by pectin into the solid yogurt.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"348 ","pages":"Article 122869"},"PeriodicalIF":10.7,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142438151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Low mechanical-hysteresis conductive hydrogel conferred by chitosan bridging and MXene nanoconfined mechanism 壳聚糖桥接和 MXene 纳米约束机制带来的低机械滞后导电水凝胶

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-10-12 DOI: 10.1016/j.carbpol.2024.122849

Jian Zou , Xin Jing , Shitao Li , Yi Chen , Yuejun Liu , Pei-Yong Feng , Xiang-Fang Peng

{"title":"Low mechanical-hysteresis conductive hydrogel conferred by chitosan bridging and MXene nanoconfined mechanism","authors":"Jian Zou , Xin Jing , Shitao Li , Yi Chen , Yuejun Liu , Pei-Yong Feng , Xiang-Fang Peng","doi":"10.1016/j.carbpol.2024.122849","DOIUrl":"10.1016/j.carbpol.2024.122849","url":null,"abstract":"<div><div>Large mechanical hysteresis, stemming from the inherent viscoelasticity of the hydrogel networks, seriously affected its service life and application scope. Herein, we introduced a synergistic approach combining MXene nanoconfinement and bridging effect to produce hydrogels with low mechanical hysteresis. The introduced MXene was able to provide an effective nanoconfined effect on the polymerization of acrylamide monomers. By synergizing with the bridging effect—facilitated by strong interactions between chitosan-grafted polyacrylamide and solvent molecules to accelerate stress transfer—we successfully developed a MXene-reinforced conductive hydrogel with mechanical hysteresis as low as 3.17 %. Additionally, the strong electrostatic interactions between the chitosan and MXene further affiliate the dispersion of MXene within the hydrogel. The resulting MXene-reinforced conductive hydrogel demonstrated remarkable temperature sensitivity (TCR = −1.42 %/°C), making it suitable to be used as a health monitoring device. These findings opened up new perspectives for the further expansion of MXene and beyond.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"348 ","pages":"Article 122849"},"PeriodicalIF":10.7,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142446069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Cellulose nanocrystal based electrospun nanofiber for biomedical applications–A review 基于纤维素纳米晶的生物医学应用电纺纳米纤维--综述

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-10-11 DOI: 10.1016/j.carbpol.2024.122838

Saifuddin Ahmed, Ratul Ahmed Khan, Taslim Ur Rashid

{"title":"Cellulose nanocrystal based electrospun nanofiber for biomedical applications–A review","authors":"Saifuddin Ahmed, Ratul Ahmed Khan, Taslim Ur Rashid","doi":"10.1016/j.carbpol.2024.122838","DOIUrl":"10.1016/j.carbpol.2024.122838","url":null,"abstract":"<div><div>Electrospinning has become a revolutionized technique for nanofiber fabrication by offering versatile procedures to precisely regulate the nanofibers' properties suitable for a wide range of advanced applications. Nanofibers are utilized as carriers for delivering medications and other health supplements as well as their ability to discharge their contents can be easily programmed and tailored in a specific manner, while serving as tissue engineering scaffolds or medical devices. Cellulose nanocrystals (CNC) are one of the most significant natural biopolymers incorporated as reinforcing agents for nanostructured fibrous frameworks. The integration of electrospinning technology and CNC offers a viable method for manufacturing nanostructured porous substances with favorable functionality, a high ratio of surface area to volume, a tunable crystal structure along with non-toxicity and cytocompatibility, outstanding mechanical properties, flexibility, sustainability, and biodegradable properties. This article offers a thorough summary of the latest progress in the application of CNC based electrospun nanofibers in various biomedical fields such as drug delivery, tissue engineering, and wound healing. It covers the techniques and parameters used for their fabrication, the different types of raw materials employed, and their application criteria. The review concludes by discussing the prospects and challenges in this rapidly evolving research domains.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"348 ","pages":"Article 122838"},"PeriodicalIF":10.7,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142446071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Development of low-molecular-weight polysaccharide-based wound dressings for full-thickness cutaneous wound healing via coacervate formation 开发基于低分子量多糖的伤口敷料，通过形成凝聚剂促进全厚皮肤伤口愈合

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-10-11 DOI: 10.1016/j.carbpol.2024.122851

Mi Wu , Dafeng Deng , Deyi Peng , Chengfeng Tan , Jianhua Lv , Wenchang Zhang , Yunen Liu , Huaqin Tian , Yan Zhao

{"title":"Development of low-molecular-weight polysaccharide-based wound dressings for full-thickness cutaneous wound healing via coacervate formation","authors":"Mi Wu , Dafeng Deng , Deyi Peng , Chengfeng Tan , Jianhua Lv , Wenchang Zhang , Yunen Liu , Huaqin Tian , Yan Zhao","doi":"10.1016/j.carbpol.2024.122851","DOIUrl":"10.1016/j.carbpol.2024.122851","url":null,"abstract":"<div><div>The development of polysaccharide-based wound dressings that are easy to prepare, adhere to tissue, adapt to diverse shapes and exhibit tunable mechanical properties holds significant clinical interest. This study introduced a simple spontaneous liquid-liquid phase separation technique employing low-molecular-weight and high polyion concentration of chitosan (CS) and hyaluronic acid (HA) to fabricate CS/HA coacervates. Upon increasing the molecular weight of chitosan from 7 kDa to 250 kDa, a transition in the CS/HA coacervates from liquid-like state to an elastic liquid and eventually to a solid-like state was observed. The resulting CS/HA coacervates demonstrated robust water resistance and adhesion to skin tissue. Notably, the molecular weight of chitosan significantly influenced the mechanical properties and hydration levels of the CS/HA coacervates. Moreover, in vivo studies using a full-thickness cutaneous defect model revealed that the CS/HA coacervates, prepared using 100 kDa chitosan, markedly accelerate wound healing. The coacervates' ease of preparation, wet adhesion, heterogeneous structure, suitability for irregularly shaped wounds, and exceptional wound healing promotion of the coacervates qualify them as an optimal wound dressing.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"348 ","pages":"Article 122851"},"PeriodicalIF":10.7,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142446067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0