Carbohydrate Polymers最新文献

Formation and physical properties of skimmed milk/low-acyl gellan gum double gels: Influence of gelation sequence 脱脂奶/低酰基结冷胶双凝胶的形成和物理性质：凝胶化顺序的影响

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-15 DOI: 10.1016/j.carbpol.2024.123012

Weibo Zhang , Chong Chen , Pengjie Wang , Jingni Xu , Feng Zhang , Jing Wang , Yinhua Zhu , Jie Luo , Liang Zhao , Fazheng Ren

{"title":"Formation and physical properties of skimmed milk/low-acyl gellan gum double gels: Influence of gelation sequence","authors":"Weibo Zhang , Chong Chen , Pengjie Wang , Jingni Xu , Feng Zhang , Jing Wang , Yinhua Zhu , Jie Luo , Liang Zhao , Fazheng Ren","doi":"10.1016/j.carbpol.2024.123012","DOIUrl":"10.1016/j.carbpol.2024.123012","url":null,"abstract":"<div><div>Low-acyl gellan gum (LA) is a typical cold- and Ca<sup>2+</sup>-set gelation polysaccharide and is widely used to improve the stability of yoghurt. Acid and endogenous calcium can induce the formation of skimmed milk (SM)/LA double gels. However, the effect of acidification temperature on the formation and physical properties of SM/LA double gels has not been elucidated. In this study, temperature above and below the LA transition temperature (38 °C) were used as acidification temperatures, which adjusted the gelation sequence of SM and LA. The LA gel prior to the SM gel formed at acidification temperature of 37 °C, exhibiting the highest WHC and G′ among all samples. Moreover, SM/LA-37 double gels showed two networks: one was a porous network and the other was a dense network. By contrast, SM/LA mixtures acidified at 42 °C formed double networks during the cooling stage, and the previously formed SM gel hindered the formation of the LA gel. Consequently, SM/LA-42 double gels showed lower WHC and G′ compared with SM/LA-37 double gels. Overall, gelation sequence substantially affected the physical properties of SM/LA double gels. Our findings provide basis for adopting optimal methods to improve yoghurt quality and revealing the gelation mechanism involved in SM/LA double gels.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"349 ","pages":"Article 123012"},"PeriodicalIF":10.7,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142663903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biodegradable, robust, and conductive bacterial cellulose @PPy-P macrofibers as resistive strain sensors for smart textiles 可生物降解、坚固耐用且导电的细菌纤维素 @PPy-P 宏纤维作为智能纺织品的电阻应变传感器

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-14 DOI: 10.1016/j.carbpol.2024.122963

Zaixian Yuan , Hai Yin , Min Zheng , Xiao Chen , Wei Peng , Hongfu Zhou , Jun Xing , Li Wang , Sanming Hu

{"title":"Biodegradable, robust, and conductive bacterial cellulose @PPy-P macrofibers as resistive strain sensors for smart textiles","authors":"Zaixian Yuan , Hai Yin , Min Zheng , Xiao Chen , Wei Peng , Hongfu Zhou , Jun Xing , Li Wang , Sanming Hu","doi":"10.1016/j.carbpol.2024.122963","DOIUrl":"10.1016/j.carbpol.2024.122963","url":null,"abstract":"<div><div>Fiber-based resistive strain sensors have attracted significant interest in the development of smart wearable devices due to their portability, flexibility, and easy conformability. However, current fiber-based resistive strain sensors mainly composed of metals and nondegradable polymers are not environmentally friendly and have poor mechanical strength. In this work, we examined biodegradable, robust, and conductive macrofibers fabricated through the in situ polymerization of p-toluenesulfonic acid (P-TSA)-doped polypyrrole (PPy) in bacterial cellulose (BC) nanofibers using wet-stretching and wet-twisting methods. The BC/PPy-P macrofibers possessed excellent conductivity (~7.19 S/cm), with superior mechanical properties (~210 MPa tensile strength and 2 GPa Young's modulus). Importantly, the BC/PPy-P microfiber operating as a resistive strain sensor possessed fast response time (15 s) and long-term stability (up to 1000 cycles), which could be used to effectively detect human movements. Moreover, the matrix material BC of BC/PPy-P macrofibers could be completely degraded within 96 h in the cellulase solution, leaving only PPy-P particles that could be recycled for other use. Therefore, the prepared BC/PPy-P microfibers provided a promising strategy for developing green resistive strain sensing fibers, with great potential to design eco-friendly smart fabric for monitoring human movements.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"349 ","pages":"Article 122963"},"PeriodicalIF":10.7,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142663935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and characterization of interpenetrating network hydrogels based on sugar beet pectin and heteroprotein complex: Structural characteristics and physicochemical properties 基于甜菜果胶和杂蛋白复合物的互穿网络水凝胶的合成与表征：结构特征与理化性质

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-14 DOI: 10.1016/j.carbpol.2024.122959

Lijia Li, Yue Liu, Xiangyun Tan, Fei Teng, Yang Li

{"title":"Synthesis and characterization of interpenetrating network hydrogels based on sugar beet pectin and heteroprotein complex: Structural characteristics and physicochemical properties","authors":"Lijia Li, Yue Liu, Xiangyun Tan, Fei Teng, Yang Li","doi":"10.1016/j.carbpol.2024.122959","DOIUrl":"10.1016/j.carbpol.2024.122959","url":null,"abstract":"<div><div>Hydrogels made from natural polymers have excellent application potential due to their good biocompatibility. However, it is difficult to maximise the benefits of hydrogels when the gel network is formed by a single substance. The purpose of this study was to investigate the relationship between the interaction of modified soybean lipophilic proteins (SLP) and lysozyme (LY) and the formation of heteroprotein complexes. Subsequently, interpenetrating network (IPN) hydrogels were further synthesized on the basis of heteroprotein (HP) complexes and sugar beet pectin (SBP) as the backbone. The strong interaction between SLP and LY drove them to spontaneously form heteroprotein complexes. The HP-SBP IPN imparted good mechanical properties to the hydrogel, which could withstand a maximum pressure of 7500 pa at 88 % strain. Meanwhile, there was still 93.52 % of water being trapped in IPN after freeze-thawing. The HP-SBP IPN hydrogels could effectively protect the encapsulated substance during UV irradiation and maintain its morphology after undergoing dynamic pH changes. Furthermore, the HP-SBP IPN hydrogels could regulate their release ability through their own swelling and achieved more than 88 % release rate in simulated intestinal fluid. Therefore, this study was expected to provide a potential strategy for the synthesis of IPN hydrogels.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"349 ","pages":"Article 122959"},"PeriodicalIF":10.7,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142663905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibacterial chitosan/organic rectorite nanocomposite-conjugated gelatin/β-cyclodextrin hydrogels with improved hemostasis performance for wound repair 具有更好止血性能的抗菌壳聚糖/有机雷克托石纳米复合-共轭明胶/β-环糊精水凝胶用于伤口修复

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-13 DOI: 10.1016/j.carbpol.2024.122961

Rong Huang , Yongqian Bian , Wenxuan Wang , Lirong Xu, Hao Zhang, Haowei Zhou, Jincheng Du, Jiaqi Li, Yuheng Zhang, Xueyong Li, Jing Li

{"title":"Antibacterial chitosan/organic rectorite nanocomposite-conjugated gelatin/β-cyclodextrin hydrogels with improved hemostasis performance for wound repair","authors":"Rong Huang , Yongqian Bian , Wenxuan Wang , Lirong Xu, Hao Zhang, Haowei Zhou, Jincheng Du, Jiaqi Li, Yuheng Zhang, Xueyong Li, Jing Li","doi":"10.1016/j.carbpol.2024.122961","DOIUrl":"10.1016/j.carbpol.2024.122961","url":null,"abstract":"<div><div>Bacterial infections and severe bleeding continue to pose significant challenges in wound repair. There is an urgent need for innovative, nature-inspired hydrogel dressings with antibacterial and hemostatic properties. A Ge-β-CD-CS-OREC conjugate hydrogel was developed by grafting β-CD and CS-OREC nanocomposites into a Ge matrix using EDC/NHS crosslinking, as confirmed by FT-IR and EDX analyses. Compared to single Ge-β-CD cross-linked hydrogels, the addition of CS-OREC enhanced the hydrogel's properties, including increased pore size (60 ± 14 μm), improved wettability (WCA = 28.82 ± 0.6°), enhanced tensile strength (41.3 ± 3.56 KPa), and strong tissue adhesion. Furthermore, this hydrogel demonstrated excellent cytocompatibility when co-cultured with keratinocytes (Kcs) and vascular endothelial cells (VECs). The incorporation of CS chains into OREC interlayers allowed the hydrogel to specifically target bacteria and increase membrane permeability in <em>Pseudomonas aeruginosa</em> (PA), <em>Klebsiella pneumoniae</em> (KP), and <em>Staphylococcus aureus</em> (SA), effectively reducing the bacterial load in infected wounds by 50.24–73.92 % compared to controls in vivo<em>.</em> Further, the hydrogel exhibited superior hemostatic efficiency (78 ± 10 s) over commercial gauze and other gels by enhancing platelet activation and coagulation factor secretion. The hydrogel accelerated tissue regeneration by promoting epithelial maturation and blood vessel regeneration, indicating its clinical potential as promising wound dressing.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"349 ","pages":"Article 122961"},"PeriodicalIF":10.7,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142654751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sheet-laminated additive manufacturing of bacterial cellulose nanofiber-reinforced hydrogels 细菌纤维素纳米纤维增强水凝胶的片状层压添加制造

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-13 DOI: 10.1016/j.carbpol.2024.122972

Junsik Choi , Kiho Sung , Jinho Hyun , Sungchul Shin

{"title":"Sheet-laminated additive manufacturing of bacterial cellulose nanofiber-reinforced hydrogels","authors":"Junsik Choi , Kiho Sung , Jinho Hyun , Sungchul Shin","doi":"10.1016/j.carbpol.2024.122972","DOIUrl":"10.1016/j.carbpol.2024.122972","url":null,"abstract":"<div><div>Three-dimensional (3D) printing of hydrogels offers promising potential for creating intricate, customizable structures with superior elasticity, softness, and biocompatibility. However, due to their high-water content, hydrogels often suffer from reduced mechanical strength, which is further decreased when they absorb water, limiting their use in environments requiring high mechanical durability. To address this, we developed a novel 3D printing technique to fabricate bacterial cellulose (BC) nanofiber-reinforced hydrogels, which we term sheet-laminated additive manufacturing (SLAM). SLAM is based on digital light processing (DLP) 3D printing technology and involves a process of sequentially layering BC nanofiber sheets impregnated with a photocrosslinkable monomer. The BC nanofiber sheets provide a unique 3D network, resulting in a significant enhancement of the mechanical strength of various photocrosslinkable hydrogels. A unique aspect of BC sheets is their ability to further improve mechanical properties by inducing nanofiber alignment or adjusting nanofiber density through stretching and compression pretreatments. The printed BC nanofiber-reinforced hydrogels maintained their strength after swelling and demonstrated exceptional performance in applications requiring high mechanical robustness. Our SLAM approach successfully created complex 3D structures, such as BC-reinforced hydrogel earthworm structures and pressure sensors, demonstrating its potential for advanced applications in high-stress environments.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"349 ","pages":"Article 122972"},"PeriodicalIF":10.7,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142663904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural and physicochemical properties of corn starch modified by phosphorylase b, hexokinase and alkaline phosphatase 经磷酸化酶 b、己糖激酶和碱性磷酸酶改性的玉米淀粉的结构和理化特性

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-13 DOI: 10.1016/j.carbpol.2024.122979

Shuo Sun , Dengyue Sun , Li Guo , Bo Cui , Feixue Zou , Jinpeng Wang , Chunrui Sun , Yu Zhu , Xueling Li

{"title":"Structural and physicochemical properties of corn starch modified by phosphorylase b, hexokinase and alkaline phosphatase","authors":"Shuo Sun , Dengyue Sun , Li Guo , Bo Cui , Feixue Zou , Jinpeng Wang , Chunrui Sun , Yu Zhu , Xueling Li","doi":"10.1016/j.carbpol.2024.122979","DOIUrl":"10.1016/j.carbpol.2024.122979","url":null,"abstract":"<div><div>To improve the functional properties of corn starch, phosphorylase <em>b</em> (PB), hexokinase (HK), and alkaline phosphatase (AP) were used to produce enzyme-modified starches (PBMS, HKMS, and APMS). The results showed that enzyme-modified starches had different phosphorus contents and degrees of substitution. The presence of P<img>O bonds and P-O-C bonds further demonstrated that phosphate groups were grafted into starch. The proportions of monostarch phosphate in PBMS, HKMS, and APMS were 77.05 %, 79.33 % and 85.88 %, respectively. The introduction of phosphate groups affected the functional properties of starch. The swelling powers of PBMS, HKMS and APMS increased from 0.99 % to 12.86 %, 10.83 % and 5.95 %, respectively. Compared to native starch (1820 mPa·s), the peak viscosities of PBMS, HKMS and APMS increased to 2655, 2838, and 2021 mPa·s, respectively. Meanwhile, the introduction of phosphate groups endowed phosphorylated starch with better freeze-thaw stability, larger paste transparency, higher solubility, and slower retrogradation rate.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"349 ","pages":"Article 122979"},"PeriodicalIF":10.7,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142654752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intervention mechanism of amphiphilic natural sweeteners on starch chain dynamic behavior: Computational and experimental insights 两亲性天然甜味剂对淀粉链动态行为的干预机制：计算和实验见解

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-12 DOI: 10.1016/j.carbpol.2024.122978

Fan Wang, Jianfu Shen, Baiyi Lu

{"title":"Intervention mechanism of amphiphilic natural sweeteners on starch chain dynamic behavior: Computational and experimental insights","authors":"Fan Wang, Jianfu Shen, Baiyi Lu","doi":"10.1016/j.carbpol.2024.122978","DOIUrl":"10.1016/j.carbpol.2024.122978","url":null,"abstract":"<div><div>Amphiphilic natural sweeteners (i.e. steviol glycosides (STE) and glycyrrhizic acid (GA)) have been adopted to improve the quality of various starchy products, which can fundamentally be characterized as the intervention of the former in the chain dynamic behavior of the latter. However, these phenomena and related mechanisms still lack systematic insights. Herein, dual-temperature molecular dynamic simulations combined with experimental analysis were used to tandemly investigate the intervention of sweeteners in six types of chain dynamic behaviors that are strongly correlated with starch properties, including unwinding, movement, long/short-term reassociation, rearrangement, and depolymerization. The results show that STE and GA both promoted the chain unwinding and movement, and also retarded the chain short/long-term reassociation and rearrangement. Besides, GA exhibited a greater role than STE in facilitating chain unwinding and movement. Peculiarly, GA (0 %–40 % w/w) collaborated with starch to form a new microstructure, especially at high content (≥ 20 % w/w), which endowed starch with exceptionally high hardness (15.50 gf→189.36 gf) and hardening rate (2.72 gf/d→17.76 gf/d), and also placed a physical barrier to retard starch depolymerization (slowly digestible starch: 11.26 %→20.62 %). This work contributes data and theoretical support for the development of starch/amphiphilic natural sweetener composite matrices.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"349 ","pages":"Article 122978"},"PeriodicalIF":10.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142663906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PVA-enhanced green synthesis of CMC-based lithium adsorption films PVA 增强型 CMC 基锂吸附薄膜的绿色合成

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-12 DOI: 10.1016/j.carbpol.2024.122973

Shengkai Liu , Huiling Li , Xi Li , Wei Wang , Chunguang Rong , Mengjie Yang , Yonggui Wang , Jing Wang , Yabei Xu , Daxin Liang , Yanjun Xie

{"title":"PVA-enhanced green synthesis of CMC-based lithium adsorption films","authors":"Shengkai Liu , Huiling Li , Xi Li , Wei Wang , Chunguang Rong , Mengjie Yang , Yonggui Wang , Jing Wang , Yabei Xu , Daxin Liang , Yanjun Xie","doi":"10.1016/j.carbpol.2024.122973","DOIUrl":"10.1016/j.carbpol.2024.122973","url":null,"abstract":"<div><div>The titanium-based lithium ion sieve (HTO), renowned for its exceptional adsorption performance and cyclic stability, was utilized in addressing the global shortage of lithium resources. However, the recovery and reuse efficiency of HTO in powder form is relatively low, which limits its application in industrial fields. To address this issue, this study utilized carboxymethyl cellulose (CMC) as the principal matrix material, while polyvinyl alcohol (PVA) played a dual function as both matrix and crosslinker, negating the necessity for supplementary crosslinking materials. Employing water as the only solvent, HTO was embedded into the CMC-PVA blended film matrix. It was observed that augmenting the CMC content substantially elevates the adsorptive capability of the film. However, this enhancement comes at the cost of reduced mechanical robustness and diminished stability in solution. Consequently, by balancing the influence of adsorptive capacity and stability through fine-tuning the CMC-to-PVA ratio. Even when HTO powder is encapsulated within the film, the adsorption film retains the excellent adsorption properties of HTO, achieving an adsorption capacity for lithium of 29.21 mg g<sup>−1</sup> within 12 h. This study provides an innovative pathway and ideas for the large-scale, low-cost production of sustainable lithium-ion adsorption materials.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"349 ","pages":"Article 122973"},"PeriodicalIF":10.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142654854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mucoadhesive polyelectrolyte complexes of fucoidan and chitin nanowhiskers to prolong the antiprotozoal activity of metronidazole 褐藻糖胶和甲壳素纳米须的黏附性聚电解质复合物延长甲硝唑的抗原虫活性

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-12 DOI: 10.1016/j.carbpol.2024.122975

Natallia V. Dubashynskaya , Valentina A. Petrova , Irina S. Ustyukhina , Andrey V. Sgibnev , Yuliya I. Cherkasova , Yuliya A. Nashchekina , Elena N. Vlasova , Dmitry P. Romanov , Yury A. Skorik

{"title":"Mucoadhesive polyelectrolyte complexes of fucoidan and chitin nanowhiskers to prolong the antiprotozoal activity of metronidazole","authors":"Natallia V. Dubashynskaya , Valentina A. Petrova , Irina S. Ustyukhina , Andrey V. Sgibnev , Yuliya I. Cherkasova , Yuliya A. Nashchekina , Elena N. Vlasova , Dmitry P. Romanov , Yury A. Skorik","doi":"10.1016/j.carbpol.2024.122975","DOIUrl":"10.1016/j.carbpol.2024.122975","url":null,"abstract":"<div><div>The improvement of the specific pharmacological activity of agents with antimicrobial and antiprotozoal properties (e.g. metronidazole, MET) is of interest for clinical applications in the treatment of bacterial infections. In this work, we prepared the polyelectrolyte complexes (PEC) based on chitin nanowhiskers (CNW) and fucoidan (FUC) with hydrodynamic diameters of 244 and 816 nm, a ζ-potential of about −22 mV and good mucoadhesive properties. The incorporation of MET into PEC particles promoted the sustained release of MET for 10 h and maintained the antiprotozoal activity against clinical isolates of <em>Trichomonas vaginalis</em> for up to 10 h. At concentrations of 1–3 mg/mL, the CWN-FUC-MET particles showed no cytotoxicity (HeLa cell line). The sustained drug release rate, combined with pronounced mucoadhesive properties, improved pharmacological activity, and non-cytotoxicity makes the developed biopolymer delivery systems promising candidates for further clinical trials.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"349 ","pages":"Article 122975"},"PeriodicalIF":10.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142654856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research on the dielectric properties of flexible β-CD/PVDF all-organic films 柔性 β-CD/PVDF 全有机薄膜的介电性能研究

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2024-11-10 DOI: 10.1016/j.carbpol.2024.122968

Ming Wang , Hongwei Lu , Bengang Li , Shijia Yang , Weitao Su

{"title":"Research on the dielectric properties of flexible β-CD/PVDF all-organic films","authors":"Ming Wang , Hongwei Lu , Bengang Li , Shijia Yang , Weitao Su","doi":"10.1016/j.carbpol.2024.122968","DOIUrl":"10.1016/j.carbpol.2024.122968","url":null,"abstract":"<div><div>All-organic dielectric polymers are currently a hot topic in the study of dielectric materials. However, it is still challenging to improve the dielectric constant, breakdown strength, and energy storage density of materials simultaneously. This study used PVDF as the matrix, and β-CD/PVDF all-organic composite dielectric films were prepared using a solution blending method. The research found that after the introduction of β-Cyclodextrin (β-CD), the β-phase content of the polymer and the crystallinity of the films were 40.9 % and 48.96 %, respectively, which are 1.1 and 1.4 times that of pure PVDF. Improved microstructure significantly enhanced the dielectric performance and energy density of the composite films with β-CD. The composite films with β-CD with dielectric constant (<em>ε</em><sub><em>r</em></sub>), breakdown strength (<em>E</em><sub><em>b</em></sub>), and energy density reaching 12.35, 401.7 MV/m, and 6.11 J/cm<sup>3</sup>, respectively, which are 1.38, 1.1, and 1.3 times that of pure PVDF. This method provides a new pathway for preparing all-organic dielectric films with high dielectric constant, high breakdown strength, and high energy density.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"349 ","pages":"Article 122968"},"PeriodicalIF":10.7,"publicationDate":"2024-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142654982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0