Carbohydrate Polymers最新文献

Expression of concern: "Synthesis and evaluation of chondroitin sulfate based hydrogels of loxoprofen with adjustable properties as controlled release carriers" [Carbohydrate Polymers volume 181, 1 February 2018, pages 1169-1179].

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-04-01 Epub Date: 2024-11-08 DOI: 10.1016/j.carbpol.2024.122957

引用次数: 0

Structural characterization and immune-modulating properties of a novel β-galactomannan extracted from black soybean hulls

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-04-01 DOI: 10.1016/j.carbpol.2025.123568

Jingwu Lu , Yaxuan Wang , Xiaojing Feng , Xuefan Zhang , Yongpo Zhang , Chunyan Gao , Congcong Yin , Xiaofang Lu , Jinzhong Zhao , Weijun Du , Aiqin Yue

{"title":"Structural characterization and immune-modulating properties of a novel β-galactomannan extracted from black soybean hulls","authors":"Jingwu Lu , Yaxuan Wang , Xiaojing Feng , Xuefan Zhang , Yongpo Zhang , Chunyan Gao , Congcong Yin , Xiaofang Lu , Jinzhong Zhao , Weijun Du , Aiqin Yue","doi":"10.1016/j.carbpol.2025.123568","DOIUrl":"10.1016/j.carbpol.2025.123568","url":null,"abstract":"<div><div>Galactomannan soluble in water (BBHW) was extracted from black soybean hulls through acid-assisted extraction and column chromatography and its immune-modulating capacity and features of the structure were elucidated. BBHW had an average molecular mass of 134,194 Da and was made up of mannose, galactose, glucose, and arabinose in a molar ratio of 1.40:1.0:0.14:0.03. The backbone structure of BBHW were primarily composed of →4)-β-D-Man<em>p</em>-(1 → and →4,6)-β-D-Man<em>p</em>-(1→, branched with α-D-Gal<em>p</em>-(1→, α-D-Gal<em>p</em>-(1 → 6)-α-D-Glc<em>p</em>-(1→, and α-L-Ara<em>f</em>-(1 → at O-6. Further examination of BBHW's molecular chains disclosed a conformation consisting of a stacked macromolecular network and a triple-helix configuration. In vitro assays demonstrated that BBHW (50–400 μg/mL) significantly improved immunological responses in RAW264.7 macrophages by increasing phagocytosis and boosting NO and cytokine release via MAPK and NF-κB signaling. These findings indicate that BBHW holds considerable potential as an immunomodulatory agent, with applications in the food and pharmaceutical industries.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"358 ","pages":"Article 123568"},"PeriodicalIF":10.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Constructing anisotropic and strong polysaccharide-based hydrogels with stretching-dehydration strategy: Effect of sodium alginate, pectin, gellan gum, and curdlan

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-04-01 DOI: 10.1016/j.carbpol.2025.123567

Jun He, Jingwen Zhao, Wenzhe Jia, Yi Cui, Siyu Wei, Yiguo Zhao, Yapeng Fang

{"title":"Constructing anisotropic and strong polysaccharide-based hydrogels with stretching-dehydration strategy: Effect of sodium alginate, pectin, gellan gum, and curdlan","authors":"Jun He, Jingwen Zhao, Wenzhe Jia, Yi Cui, Siyu Wei, Yiguo Zhao, Yapeng Fang","doi":"10.1016/j.carbpol.2025.123567","DOIUrl":"10.1016/j.carbpol.2025.123567","url":null,"abstract":"<div><div>Polysaccharide-based hydrogels are widely utilized in the food industry and materials science due to their safety and abundance from natural sources. However, their functionality is often limited by poor mechanical properties, primarily due to their simple and isotropic structures. In this study, the stretching-dehydration (SD) processing was applied to create anisotropic structure and enhance the mechanical properties in polysaccharide-based hydrogels, specifically sodium alginate (SA), pectin (PE), gellan gum (GG), and curdlan (CU). Among these, low molecular weight sodium alginate (SA-L) hydrogel exhibited notable stretching-induced anisotropy and structural stability during dehydration. Furthermore, increasing the controlled strains (CSN) could improve anisotropy, stretching strength, and Young's modulus which reached up to 100 MPa in anisotropic SA-L hydrogel. The anisotropic hydrogels closely mimicked the microstructure of whole-muscle foods. Sensory evaluations highlighted the enhanced chewiness and hardness, suggesting the anisotropic hydrogels are promising candidates for emulating whole-muscle textures. This work highlights the potential of anisotropic hydrogels produced through simple SD treatment as advanced materials for both food and biomimetic applications.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"359 ","pages":"Article 123567"},"PeriodicalIF":10.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143769350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A sustainable alginate-based multifunctional porous material with integrated thermal barrier and reversible fire warning for enhanced building protection

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-03-31 DOI: 10.1016/j.carbpol.2025.123563

Md Hasib Mia , Yuhang Wan , Qing Jiang , Lele Huang , Mi Zhou , Jie Xu , Xiaoli Gong , Xiaodong Hu , Zhicai Yu , Hualing He

{"title":"A sustainable alginate-based multifunctional porous material with integrated thermal barrier and reversible fire warning for enhanced building protection","authors":"Md Hasib Mia , Yuhang Wan , Qing Jiang , Lele Huang , Mi Zhou , Jie Xu , Xiaoli Gong , Xiaodong Hu , Zhicai Yu , Hualing He","doi":"10.1016/j.carbpol.2025.123563","DOIUrl":"10.1016/j.carbpol.2025.123563","url":null,"abstract":"<div><div>The need for innovative bio-based building material development that solves excessive energy consumption and environmental sustainability and enables thermal barrier with sensitive early fire warnings is urgent. This study focuses on developing a sustainable multifunctional SNAP (sodium alginate/nickel oxide/ammonium polyphosphate/polypyrrole) porous material, fabricated by incorporating sodium alginate (NaAlg) as the primary structural matrix, ammonium polyphosphate (APP) as a flame retardant, nickel oxide (NiO) for temperature sensing and enhanced flame retardancy, and polypyrrole (PPy) to improve electrical conductivity for fire warning functionality. The inclusion of APP, NiO, and PPy significantly improved the limiting oxygen index to 48.7 %, and a robust char layer during flame exposure provided effective thermal barrier and self-extinguishing properties. The porous material exhibited thermal conductivity of 0.076 W·m<sup>−1</sup>·K<sup>−1</sup>. The synergistic integration of NiO and PPy enhanced temperature sensing and electrical conductivity, enabling ultrafast (0.9 s) flame detection and a stable fire warning period of 227 s (under continuous exposure) with reversible warning characteristics. Post-crosslinking with Ca<sup>2+</sup> ion improved mechanical strength (0.32 MPa) and maintained stability up to 48 h of immersion in deionized water. This innovative, environmentally friendly composite material holds significant promise in advanced building materials where high fire safety and early warning systems are critical.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"358 ","pages":"Article 123563"},"PeriodicalIF":10.7,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143760306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Construction and mechanism of konjac glucomannan-based laminated flexible sensor hydrogel

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-03-30 DOI: 10.1016/j.carbpol.2025.123564

Junying Wu , Di Zhang , Xianrui Chen , Xiangyun Sun , Jun Liao , Jie Pang , Shuyi Wu

{"title":"Construction and mechanism of konjac glucomannan-based laminated flexible sensor hydrogel","authors":"Junying Wu , Di Zhang , Xianrui Chen , Xiangyun Sun , Jun Liao , Jie Pang , Shuyi Wu","doi":"10.1016/j.carbpol.2025.123564","DOIUrl":"10.1016/j.carbpol.2025.123564","url":null,"abstract":"<div><div>Flexible hydrogel-based sensors show great potential but face challenges in dehydration for long-term storage and customization for various deformation measurements. This work reports a strategy for preparing hydrogel sensors by creating dry sensor films with different properties, which are rehydrated and laminated for specific applications. A polyhydroxyalkanoate (PHA) nanofiber membrane, produced via microfluidic blow spinning and combined with conductive Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> (MXene), achieved a Young's modulus of 46.59 MPa. A biomass polysaccharide hydrogel made from konjac glucomannan, xanthan gum, and sodium alginate (SA) encapsulated the PHA/MXene membrane. The Young's modulus and load testing of the hydrogel sensors can be adjusted by varying SA concentration. The gel-encapsulated films can be dried for long-term preservation. For applications, the dried layers with different SA concentrations were rehydrated and assembled according to load requirements. Crosslinking between Ca<sup>2+</sup> ions and SA's carboxyl groups ensures stable interlayer bonding. Numerical simulations showed that the laminated sensor, combining soft and hard layers, responds well to various external forces. The laminated sensor captured multiple electrical signals to differentiate shear and compressive loads, which is a challenge for traditional flexible devices. This study presents a customizable laminated sensor that can be tailored to specific measurement ranges, enhancing hydrogel-based sensing technologies.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"358 ","pages":"Article 123564"},"PeriodicalIF":10.7,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Multi-active-site antibacterial modification of dopamine-hyaluronic acid hydrogel with N-halamine for skin tissue engineering

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-03-30 DOI: 10.1016/j.carbpol.2025.123565

Chenghao Li , Saren Gerile , Nan Du , Liang Zou , Zhiqiang Wang , Yanfang Liu , Jili Hou , Kuntong Song , Yuanhao Xiao , Hui Ren , Jing Kang , Alideertu Dong , Run Xu

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Advances in fucoidan and fucoidan oligosaccharides: Current status, future prospects, and biological applications

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-03-28 DOI: 10.1016/j.carbpol.2025.123559

Hamed I. Hamouda , Tang Li , Samah Shabana , Amr H. Hashem , Heng Yin

{"title":"Advances in fucoidan and fucoidan oligosaccharides: Current status, future prospects, and biological applications","authors":"Hamed I. Hamouda , Tang Li , Samah Shabana , Amr H. Hashem , Heng Yin","doi":"10.1016/j.carbpol.2025.123559","DOIUrl":"10.1016/j.carbpol.2025.123559","url":null,"abstract":"<div><div>Sulfated polysaccharides (SPS) derived from seaweeds are precious bioactive compounds of diverse biological activities. Fucoidan is a complex SPS composed of L-fucose and sulfate groups, can be extracted from brown seaweeds, as well as microbial, insect, plant glycans, and marine invertebrates. It has gained considerable attention due to its anti-inflammatory, anticancer, antiviral, antithrombotic, hypolipidemic, and immune-modulatory properties. Recent research has focused on the extraction and extensive characterization of fucoidan. Its structural complexity, influenced by species, sources, and harvesting conditions, directly influences its bioactivity, with higher sulfation and lower molecular weight enhancing its activity. Interestingly, fucoidan oligosaccharides (FOs) play a critical role in various metabolic processes and hold significant potential in disease diagnostics. This comprehensive review explores the current status of fucoidan research, covering its sources, extraction and purification techniques, structural variations and biological activities. Additionally, we highlight its potential health benefits, providing insights for researchers interested in sulfated polysaccharides.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"358 ","pages":"Article 123559"},"PeriodicalIF":10.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143760305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Acetyl and pyruvate groups affect the synergistic interaction between xanthan gum and Gleditsia sinensis polysaccharide by regulating the conformational transition of xanthan gum

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-03-28 DOI: 10.1016/j.carbpol.2025.123558

Yantao Liu , Diming Li , Conghui Feng , Junxian Hu , Pengfei Li , Liang He , Nan Yang , Katsuyoshi Nishinari

{"title":"Acetyl and pyruvate groups affect the synergistic interaction between xanthan gum and Gleditsia sinensis polysaccharide by regulating the conformational transition of xanthan gum","authors":"Yantao Liu , Diming Li , Conghui Feng , Junxian Hu , Pengfei Li , Liang He , Nan Yang , Katsuyoshi Nishinari","doi":"10.1016/j.carbpol.2025.123558","DOIUrl":"10.1016/j.carbpol.2025.123558","url":null,"abstract":"<div><div>The contents of acetyl and pyruvate groups in XG is one of the important factors affecting its order-disorder conformation. However, with the deepening of study on the interaction between XG and other polysaccharides, the impact of this fine structure on the synergistic interaction is still unclear. To resolve this problem, a strategy mainly based on rheology was developed in this study. The deacetylated and depyruvated derivatives were prepared and characterized using FT-IR, XRD, and TG. Moreover, the quantitative results indicated that the acetyl content in Dea-XG is 0.043 % (<em>w/w</em>), and the content of pyruvate group in Dep-XG is 0.99 % (<em>w/w</em>). Rheological experiments revealed that Dea-XG exhibited stronger interactions with GSP (higher viscosity and modulus) compared with XG, while Dep-XG showed weaker synergy. The results of temperature sweep indicated that the binding temperatures of Dea-XG and XG with GSP are above the point of transition from disorder to order of the XG conformation, while Dep-XG is opposite. Temperature-dependent studies further confirm that XG fine structures enhance synergistic effects with GSP by increasing the disordered structure, while increasing the ordered structures inhibit them. This study provides a new idea for comprehensive understanding of the synergistic mechanism between XG and GSP.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"358 ","pages":"Article 123558"},"PeriodicalIF":10.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143747420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The mutual effect of dietary fiber and polyphenol on gut microbiota: Implications for the metabolic and microbial modulation and associated health benefits

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-03-28 DOI: 10.1016/j.carbpol.2025.123541

Bo Cheng , Hongyan Feng , Cheng Li , Fei Jia , Xiaowei Zhang

{"title":"The mutual effect of dietary fiber and polyphenol on gut microbiota: Implications for the metabolic and microbial modulation and associated health benefits","authors":"Bo Cheng , Hongyan Feng , Cheng Li , Fei Jia , Xiaowei Zhang","doi":"10.1016/j.carbpol.2025.123541","DOIUrl":"10.1016/j.carbpol.2025.123541","url":null,"abstract":"<div><div>Gut microbiota plays a critical role in maintaining human health by regulating digestion, metabolism, and immune function. Emerging research highlights the potential of dietary interventions, particularly dietary fiber (DF) and polyphenols, in modulating gut microbiota composition and function. DF serves as a fermentable substrate for beneficial gut bacteria, promoting the production of short-chain fatty acids (SCFAs). Polyphenols, a diverse group of bioactive compounds selectively modulate microbial populations and contribute to the production of bioactive metabolites with host health benefits. Importantly, the interplay between DF and polyphenols creates a synergistic effect within the gut microbiome, shaping microbial diversity, enhancing SCFAs production, and strengthening gut barrier function, which together support metabolic and immune homeostasis. This review systematically explores the synergistic effects of DF-polyphenol combinations on gut microbiota modulation, microbial metabolites, and their implications for overall health. The combined effects of DF and polyphenols hold promise for targeted nutritional strategies in preventing metabolic disorders and improving gut health. Moreover, the extent of these benefits is influenced by the structural characteristics of DF, the source and dosage of polyphenols, and individual gut microbiota composition. Further research is warranted to optimize DF-polyphenol interactions and facilitate their applications in personalized nutrition and functional food development.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"358 ","pages":"Article 123541"},"PeriodicalIF":10.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143760304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Refined regulation of polysaccharide biosynthesis in edible and medicinal fungi: From pathways to production

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-03-28 DOI: 10.1016/j.carbpol.2025.123560

Yuxi Guo , Mengmeng Xu , Jing Zhang , Zhongbao Ma , Jiahao Cuia , Liting Zhao , Lei Chen , Guiyang Shi , Zhongyang Ding

{"title":"Refined regulation of polysaccharide biosynthesis in edible and medicinal fungi: From pathways to production","authors":"Yuxi Guo , Mengmeng Xu , Jing Zhang , Zhongbao Ma , Jiahao Cuia , Liting Zhao , Lei Chen , Guiyang Shi , Zhongyang Ding","doi":"10.1016/j.carbpol.2025.123560","DOIUrl":"10.1016/j.carbpol.2025.123560","url":null,"abstract":"<div><div>Polysaccharides derived from edible and medicinal fungi (EMF) exhibit various biological activities, rendering them useful in the pharmaceutical, nutraceutical, and food industries. However, their intricate biosynthetic pathways limit their potential, necessitating a deeper understanding of their structure–function relationships. <em>Ganoderma lucidum</em> has emerged as a key model for elucidating polysaccharide biosynthesis in EMF. In this paper, we present a comprehensive review of the current state of research on EMF polysaccharide biosynthesis from the perspective of structure and biosynthetic pathways, and concentrate on strategies for enhancing the precise regulation of polysaccharide production. The complexity of these structures, governed by a refined biosynthetic pathway, is crucial for determining their functional diversity. This review highlights three key strategies for enhancing polysaccharide production. Genome-scale metabolic remodeling is useful for the systematic design and optimization of pathways, while profiling metabolic remodeling regulates critical genes and metabolic nodes. The regulation of enzyme activity, particularly glycosyltransferases and glycoside hydrolases, can enhance biosynthetic efficiency. Furthermore, this review identifies several future challenges pertaining to polysaccharide synthesis. We establish a robust foundation for the advanced bio-manufacturing of polysaccharides, and provide theoretical guidance, along with empirical support, to precisely regulate polysaccharide synthesis in EMF, underscoring their significance as functional foods.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"358 ","pages":"Article 123560"},"PeriodicalIF":10.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0