Survey of ophthalmology最新文献_第3页

Impact of artificial intelligence in vision science: A systematic review of progress, emerging trends, data domain quantification, and critical gaps. 人工智能在视觉科学中的影响：对进展、新趋势、数据域量化和关键差距的系统回顾。

IF 5.9 2区医学

Survey of ophthalmology Pub Date : 2025-09-16 DOI: 10.1016/j.survophthal.2025.09.014

Colby F Lewallen, Davide Ortolan, Dominik Reichert, Ruchi Sharma, Kapil Bharti

{"title":"Impact of artificial intelligence in vision science: A systematic review of progress, emerging trends, data domain quantification, and critical gaps.","authors":"Colby F Lewallen, Davide Ortolan, Dominik Reichert, Ruchi Sharma, Kapil Bharti","doi":"10.1016/j.survophthal.2025.09.014","DOIUrl":"10.1016/j.survophthal.2025.09.014","url":null,"abstract":"The prominence of artificial intelligence (AI) is growing exponentially, yet its implementation across research domains is uneven. To quantify AI trends in vision science, we evaluated over 100,000 PubMed article metadata spanning 35 years. Using Medical Subject Headings (MeSH) terms, we analyzed trends across four prominent ocular diseases: age-related macular degeneration, diabetic retinopathy, glaucoma, and cataract. Most articles utilized research techniques from at least one of the following domains: biological models, molecular profiling, image-based analysis, and clinical outcomes. Our quantification reveals that AI prominence is disproportionally concentrated in the image-based analysis domain, and, additionally, among 4 diseases evaluated, AI prevalence in cataract research is lagging. Contributing factors towards these disparities include insufficient data standardization, complex data structures, limited data availability, unresolved ethical concerns, and not gaining meaningful improvements over human-based interpretations. By mapping where AI thrives and where it lags, we offer a quantitative reference for funding agencies, clinicians, and vision scientists. Connecting various research domains with multimodal and generative AI could improve diagnostic utility; enabling earlier diagnosis, personalized therapy, reduced healthcare costs, and accelerate innovation. Future work should move AI in vision science beyond image-centric pattern recognition toward integrative, mechanistic analyses that explain - rather than merely detect - disease.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interventions to improve patients' knowledge in ophthalmology: A systematic review and narrative synthesis. 提高患者眼科知识的干预措施：系统回顾和叙述综合。

IF 5.9 2区医学

Survey of ophthalmology Pub Date : 2025-09-13 DOI: 10.1016/j.survophthal.2025.09.006

Dayyanah Sumodhee, Estelle Ioannidou, Rishi Ramessur, Jai Prashar, Mohammed Abbas, Konstantinos Balaskas, Nikolas Pontikos, Peter Thomas

{"title":"Interventions to improve patients' knowledge in ophthalmology: A systematic review and narrative synthesis.","authors":"Dayyanah Sumodhee, Estelle Ioannidou, Rishi Ramessur, Jai Prashar, Mohammed Abbas, Konstantinos Balaskas, Nikolas Pontikos, Peter Thomas","doi":"10.1016/j.survophthal.2025.09.006","DOIUrl":"10.1016/j.survophthal.2025.09.006","url":null,"abstract":"Low eye health knowledge is associated with suboptimal treatment adherence, self-care practice and follow-up rate leading to poorer outcomes. The aim of this review was to survey what interventions are effective at improving patients' knowledge of eye disease and treatments. Randomised controlled trials and cross-sectional studies delivering interventions to improve patients' knowledge about eye diseases were reviewed. Databases, grey literature, reference lists and journals were searched for relevant studies. Three authors reviewed and extracted the data and assessed quality. Seventeen publications were included examining different types of interventions. Thirteen studies showed significant improvements on patients' eye disease knowledge following intervention. These included all 5 verbal interventions, 5 out of 6 video interventions, 5 out of 8 written or image material interventions, and 1 out of 2 using other formats. Study quality varied, with 7 studies rated as having low risks of bias, 8 moderate, and 2 high. Intervention design varied considerably across studies, making comparisons challenging. Interventions to improve patients' knowledge of eye conditions show promising results in particular verbal and video interventions; however, higher quality studies, as well as standardisation of reporting and intervention formats, are required to strengthen the evidence base.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radiological features of lacrimal gland masses. 泪腺肿块的影像学特征。

IF 5.9 2区医学

Survey of ophthalmology Pub Date : 2025-09-13 DOI: 10.1016/j.survophthal.2025.09.005

Sonia Huang, Jessica Y Tong, Valerie Juniat, Abdullah Almater, Ilse Mombaerts, Dinesh Selva

引用次数: 0

Current advances in dome-shaped macula and associated conditions. 穹顶状黄斑及其相关疾病的最新进展。

IF 5.9 2区医学

Survey of ophthalmology Pub Date : 2025-09-06 DOI: 10.1016/j.survophthal.2025.09.004

Matteo Mario Carlà, Elise Philippakis, David Gaucher, Aude Couturier, Alain Gaudric

{"title":"Current advances in dome-shaped macula and associated conditions.","authors":"Matteo Mario Carlà, Elise Philippakis, David Gaucher, Aude Couturier, Alain Gaudric","doi":"10.1016/j.survophthal.2025.09.004","DOIUrl":"10.1016/j.survophthal.2025.09.004","url":null,"abstract":"Dome-shaped macula (DSM) is a distinctive anatomical entity characterized by an inward convexity of the macula, initially described in highly myopic eyes within posterior staphyloma, but is now recognized as occurring across a broader spectrum of refractive conditions, including mild myopia and even emmetropia. Since its initial description in 2008, advances in imaging technologies and longitudinal studies have significantly improved our understanding of DSM. We analyzed the recent literature, focusing on publications from the last 10 years. DSM affects about 0.2 % of the general population, with a prevalence reaching 10-20 % in highly myopic eyes. Its pathophysiology involves complex mechanisms ranging from emmetropization processes in non-myopic eyes to differential scleral biomechanics and asymmetric posterior segment growth in high myopia. Polarization-sensitive optical coherence tomography provided new insights into scleral fiber architecture, showing horizontal interpapillomacular fibers corresponding to the typical horizontal DSM configuration. DSM plays a dual role in myopic complications, potentially protecting against foveal retinoschisis while predisposing to serous retinal detachment (SRD) and retinal pigment epithelium (RPE) atrophy when the dome height exceeds specific thresholds. SRD, the most common (8-50 % of cases), and RPE atrophy are the main complications directly related to DSM. There are numerous treatment approaches for SRD with variable success rates. Longitudinal studies have described DSM evolution over time and shown that an increased dome height correlated with the axial elongation. We provide updated information on the epidemiology, pathophysiology, clinical presentation and management of DSM to improve the diagnosis and treatment of this increasingly recognized condition.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Choroidal vascularity index as a marker of health and disease: systematic review and meta-analyses. 脉络膜血管指数作为健康和疾病的标志：系统回顾和荟萃分析。

IF 5.9 2区医学

Survey of ophthalmology Pub Date : 2025-09-05 DOI: 10.1016/j.survophthal.2025.09.003

Nicholas Chieh Loh, William Rojas-Carabali, Yuan Heng Lim, Jo Earn Bong, Valeria Villabona-Martinez, Carlos Cifuentes-González, Meenakshi Kumar, Srinivas Sadda, Leopold Schmetterer, Chui Ming Gemmy Cheung, Vishali Gupta, Dilraj S Grewal, Sharon Fekrat, Alejandra de-la-Torre, Bernett Lee, Xin Wei, Lisa Nivison-Smith, Rupesh Agrawal

{"title":"Choroidal vascularity index as a marker of health and disease: systematic review and meta-analyses.","authors":"Nicholas Chieh Loh, William Rojas-Carabali, Yuan Heng Lim, Jo Earn Bong, Valeria Villabona-Martinez, Carlos Cifuentes-González, Meenakshi Kumar, Srinivas Sadda, Leopold Schmetterer, Chui Ming Gemmy Cheung, Vishali Gupta, Dilraj S Grewal, Sharon Fekrat, Alejandra de-la-Torre, Bernett Lee, Xin Wei, Lisa Nivison-Smith, Rupesh Agrawal","doi":"10.1016/j.survophthal.2025.09.003","DOIUrl":"10.1016/j.survophthal.2025.09.003","url":null,"abstract":"The Choroidal Vascularity Index (CVI), derived from optical coherence tomography (OCT), has emerged as a potential biomarker for detecting vascular changes. Understanding its variability across physiological states, ocular conditions, and systemic diseases is crucial for its integration into clinical practice. We evaluated variations in CVI across different physiological states (e.g., first-trimester pregnancy), ocular conditions (e.g., age-related macular degeneration[AMD]), and systemic diseases (e.g., diabetes mellitus) compared to healthy controls. From 1210 identified articles, 63 studies (7316 participants: 4000 controls and 3316 cases) met inclusion criteria. Data covered 12 distinct conditions and physiological states. Most studies were conducted in Europe and Asia, predominantly using spectral-domain OCT machines with a low risk of bias. Increased CVI was seen in some physiological states (e.g., Valsalva maneuver, first-trimester pregnancy) and some disorders (e.g. active panuveitis, inactive thyroid eye disease). Reduced CVI was found in diabetes mellitus (both with or without diabetic retinopathy), hyperopic amblyopia, and AMD. CVI demonstrates potential as a biomarker to differentiate between physiological states and pathological conditions compared to healthy controls. These findings underscore the choroid's adaptive response to systemic and ocular challenges, highlighting CVI's relevance in understanding disease mechanisms and monitoring health.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dissecting the clinical and pathophysiological complexity of fundus tessellation. 剖析眼底镶嵌的临床和病理生理复杂性。

IF 5.9 2区医学

Survey of ophthalmology Pub Date : 2025-09-04 DOI: 10.1016/j.survophthal.2025.09.001

Ramesh Venkatesh, Pratibha Hande, Vishma Prabhu, Shruthi Vidyasagar, Karishma Tendulkar, Rupak Roy, Kanika Godani, Alisha Sirsikar, Preksha Biradar, Priyanka Gandhi, Naresh Kumar Yadav, Jay Chhablani

{"title":"Dissecting the clinical and pathophysiological complexity of fundus tessellation.","authors":"Ramesh Venkatesh, Pratibha Hande, Vishma Prabhu, Shruthi Vidyasagar, Karishma Tendulkar, Rupak Roy, Kanika Godani, Alisha Sirsikar, Preksha Biradar, Priyanka Gandhi, Naresh Kumar Yadav, Jay Chhablani","doi":"10.1016/j.survophthal.2025.09.001","DOIUrl":"10.1016/j.survophthal.2025.09.001","url":null,"abstract":"Fundus tessellation (FT)-also referred to as tigroid or mosaic fundus-is characterized by increased visibility of underlying choroidal vessels. While often a physiological finding, FT may also signal early pathology in conditions such as high myopia, choroidal atrophy, or pigmentary disorders. We synthesize current understanding of the anatomical, optical, and imaging factors influencing FT appearance, including the roles of axial elongation, melanin distribution, and media clarity. Advances in multimodal imaging-such as color fundus photography, optical coherence tomography, and fundus autofluorescence-have improved the ability to differentiate physiological FT from disease-associated changes. Furthermore, artificial intelligence-driven tools like the Fundus Tessellation Density Index (FTDI) provide quantitative support for clinical decision-making. We propose a structured framework combining clinical parameters, imaging features, and FTDI to guide diagnosis and risk assessment. We underscore the clinical relevance of accurately distinguishing physiological from pathological FT and highlights directions for future research, including the potential of FTDI as a prognostic biomarker.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of lipid metabolism disorder in the progression and treatment of ocular vascular diseases. 脂质代谢紊乱在眼部血管疾病进展和治疗中的作用。

IF 5.9 2区医学

Survey of ophthalmology Pub Date : 2025-09-04 DOI: 10.1016/j.survophthal.2025.09.002

Weichen Song, Wen Chen, Jingyi Chi, Xinyu Liu, Wenwen Zhu

{"title":"The role of lipid metabolism disorder in the progression and treatment of ocular vascular diseases.","authors":"Weichen Song, Wen Chen, Jingyi Chi, Xinyu Liu, Wenwen Zhu","doi":"10.1016/j.survophthal.2025.09.002","DOIUrl":"10.1016/j.survophthal.2025.09.002","url":null,"abstract":"Lipid metabolism plays a critical role in maintaining normal physiological functions and is strongly linked to the pathogenesis of ocular vascular diseases. We examine how disorders of lipid metabolism drive progression in ocular vascular diseases, including diabetic retinopathy, age-related macular degeneration, retinal vascular occlusive diseases, and retinopathy of prematurity. These disorders are classified as a related group due to their common feature of impaired ocular vascularization. Glaucoma has also been increasingly recognized as a condition resulting from both retinal and choroidal blood flow abnormalities, with shared lipid metabolism disturbances contributing to its pathogenesis. Lipid components such as fatty acids may exacerbate retinal and choroidal damage by promoting neovascularization and inflammatory responses. Additionally, lipid metabolic dysregulation negatively influences the retinal and choroidal microenvironment by increasing oxidative stress and inhibiting autophagy. We also discuss emerging therapeutic strategies targeting lipid metabolism, highlighting their potential in preventing or mitigating ocular vascular diseases. These include lipid-modulating agents and their use in combination with established therapies. Understanding the influence of lipid metabolism on the pathophysiology of these diseases could pave the way for the development of novel treatment approaches. These advancements hold potential to improve visual prognosis in patients with ocular vascular diseases. Identifying the specific roles and molecular targets associated with lipid metabolism in ocular vascular diseases will offer valuable insights into disease mechanisms. This knowledge will lay the groundwork for personalized and more effective clinical interventions.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predicting treatment response in retinal vein occlusions using baseline optical coherence tomography biomarkers: A systematic review. 使用基线光学相干断层扫描生物标志物预测视网膜静脉闭塞的治疗反应：系统综述。

IF 5.9 2区医学

Survey of ophthalmology Pub Date : 2025-09-04 DOI: 10.1016/j.survophthal.2025.08.016

Amin Hatamnejad, Keean Nanji, Justin Grad, Abdullah El-Sayes, Andrew Mihalache, Mohamed Gemae, Ryan Huang, Nadia K Waheed, David Sarraf, SrinVas R Sadda, Tien Yin Wong, Dena Zeraatkar, Jinhiu Ma, Sunir J Garg, Marion R Munk, Enrico Borrelli, David H Steel, Sobha Sivaprasad, Charles C Wykoff, Varun Chaudhary

{"title":"Predicting treatment response in retinal vein occlusions using baseline optical coherence tomography biomarkers: A systematic review.","authors":"Amin Hatamnejad, Keean Nanji, Justin Grad, Abdullah El-Sayes, Andrew Mihalache, Mohamed Gemae, Ryan Huang, Nadia K Waheed, David Sarraf, SrinVas R Sadda, Tien Yin Wong, Dena Zeraatkar, Jinhiu Ma, Sunir J Garg, Marion R Munk, Enrico Borrelli, David H Steel, Sobha Sivaprasad, Charles C Wykoff, Varun Chaudhary","doi":"10.1016/j.survophthal.2025.08.016","DOIUrl":"10.1016/j.survophthal.2025.08.016","url":null,"abstract":"This systematic review examines the prognostic value of baseline optical coherence tomography (OCT) biomarkers in predicting visual acuity (VA) outcomes for eyes with macular edema secondary to retinal vein occlusions (RVO) treated with anti-VEGF therapies, steroids, laser photocoagulation, or combination treatments. VA predictions at 6, 12, and 24 months post-treatment were assessed using a narrative synthesis approach and vote counting based on effect direction relative to a minimal clinically important difference. Certainty of evidence was evaluated using GRADE guidelines. Confounding factors, biomarker variability, and inconsistent outcome measurements were critically analyzed. A total of 116 studies assessing 31 unique OCT biomarkers were included. 'Low' certainty evidence indicated that an intact external limiting membrane (ELM) at baseline predicted better VA at 6 months, while baseline ellipsoid zone (EZ) integrity predicted better VA at 12 months at 5-letter change, however, these associations were not observed at thresholds of 10 and 15 letters. Certainty of evidence was often downgraded due to confounding factors, variability in biomarker definitions, and inconsistent outcomes. These findings highlight OCT biomarkers' potential for prognostication in RVO patients, but underscore the need for standardized definitions and further research to address confounders, improving the reliability and clinical utility of OCT-based biomarkers.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection and quantification of fluorescein angiography leakage: From manual grading to advances in machine learning. 荧光素血管造影渗漏的检测和定量：从人工分级到机器学习的进展。

IF 5.9 2区医学

Survey of ophthalmology Pub Date : 2025-09-01 DOI: 10.1016/j.survophthal.2025.08.015

Uday Pratap Singh Parmar, Atul Arora, Aniruddha Agarwal, Sapna Gangaputra, Rupesh Agrawal, Vishali Gupta

{"title":"Detection and quantification of fluorescein angiography leakage: From manual grading to advances in machine learning.","authors":"Uday Pratap Singh Parmar, Atul Arora, Aniruddha Agarwal, Sapna Gangaputra, Rupesh Agrawal, Vishali Gupta","doi":"10.1016/j.survophthal.2025.08.015","DOIUrl":"10.1016/j.survophthal.2025.08.015","url":null,"abstract":"Fluorescein angiography (FA) has long been a cornerstone for evaluating retinal vascular leakage in diseases like uveitis, diabetic retinopathy, and macular degeneration, but its interpretation relies on subjective grading that can vary between clinicians. With the emergence of artificial intelligence (AI), there is a push to transform this qualitative assessment into objective, quantifiable metrics. We conducted a comprehensive literature search using PubMed, Embase, and Scopus, combining keywords and MeSH terms related to fluorescein angiography leakage, artificial intelligence, and retinal vascular diseases. Studies were included if they assessed FA leakage using manual, semi-automated, or AI-based methods and were peer-reviewed, published in English, and focused on human subjects. Our review charts the evolution from manual grading to modern machine learning techniques that segment and measure leakage using various angiograms. These AI-based approaches enable standardized, reproducible leakage indices that correlate with disease severity, inform treatment decisions, stratify high-risk patients, and facilitate sensitive monitoring of therapeutic response. We also introduce the concept of \"minimal residual disease\" in this context. By moving from coarse, subjective estimations to precise digital biomarkers, AI-driven FA leakage quantification promises to improve clinical care and research endpoints in retinal disease.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A narrative review of the psychological impact of intravitreal injections. 玻璃体内注射对心理影响的述评。

IF 5.9 2区医学

Survey of ophthalmology Pub Date : 2025-08-28 DOI: 10.1016/j.survophthal.2025.08.017

Nicholas George Giannopoulos, Carmelo Zak Macri, Isuri Apsara Kumari Seneviratne, Stephen Bacchi, Michelle Tian Sun, Weng Onn Chan

{"title":"A narrative review of the psychological impact of intravitreal injections.","authors":"Nicholas George Giannopoulos, Carmelo Zak Macri, Isuri Apsara Kumari Seneviratne, Stephen Bacchi, Michelle Tian Sun, Weng Onn Chan","doi":"10.1016/j.survophthal.2025.08.017","DOIUrl":"10.1016/j.survophthal.2025.08.017","url":null,"abstract":"Intravitreal injections (IVI) are a common, effective therapy for multiple retinal diseases although can be associated with significant psychological effects that reduce adherence to treatment. We reviewed the psychological impacts of IVI to characterise their causes, consequences, and solutions. We searched the electronic databases PubMed, OVID Medline, OVID Embase, Google Scholar and Cochrane Reviews and retrieved 1252 peer-reviewed articles. Thirty-four articles were ultimately included and analysed. The majority of retrieved articles pertained to anxiety; however, other impacts were also identified with limited available evidence regarding depression. Pre-procedural anxiety was generally mild to moderate and reported in 17.3-85 % of patients undergoing IVI. Key contributing factors to anxiety included a lack of patient education, pain and discomfort during the procedure, and travel and waiting times. Potential strategies to reduce anxiety included person-centred education, alternatives to speculum use, reducing clinic wait times, and music or handholding during the procedure. Patients experience significant anxiety from IVI, owing to multiple factors, including lack of education about the procedure, lack of procedural familiarity, and pain, which require a patient-centred approach to addressing that considers individual needs and preferences. Little data pertain to non-anxiety effects of IVI, and thus further research may identify additional barriers to adherence and their solutions.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144969816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0