Survey of ophthalmology最新文献

Pharmacological agents for treatment of proliferative vitreoretinopathy: A systematic review and network meta-analysis.

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-03-01 DOI: 10.1016/j.survophthal.2025.02.005

Sina Khosravi Mirzaei, Firouze Hatami, Sare Safi, Zahra Khorrami, Fatemeh Khosravi Shadmani, Seyed Mohamadmehdi Moshtaghion, Hamid Ahmadieh

{"title":"Pharmacological agents for treatment of proliferative vitreoretinopathy: A systematic review and network meta-analysis.","authors":"Sina Khosravi Mirzaei, Firouze Hatami, Sare Safi, Zahra Khorrami, Fatemeh Khosravi Shadmani, Seyed Mohamadmehdi Moshtaghion, Hamid Ahmadieh","doi":"10.1016/j.survophthal.2025.02.005","DOIUrl":"https://doi.org/10.1016/j.survophthal.2025.02.005","url":null,"abstract":"We performed a comprehensive systematic review and network meta-analysis (NMA) to assess the efficacy of pharmacological agents for the treatment of proliferative vitreoretinopathy (PVR) following retinal detachment (RD) surgery. A systematic search was performed across PubMed, Scopus, Web of Science, and Embase. Randomized and non-randomized controlled trials and comparative observational studies evaluating the effect of pharmacological agents in a clinical setting were included. The primary outcome was retinal reattachment rate, and secondary outcomes were PVR recurrence, reoperation, intraocular pressure (IOP), epiretinal membrane (ERM), and macular edema. A total of 23 studies with 1749 eyes were included. Twelve different drugs or drug combinations were assessed. The NMA was performed for retinal reattachment, PVR recurrence, and reoperation rate outcomes. Among the pharmacological agents analyzed, adjunctive therapy with 13-cis-retinoic acid (13-cis-RA) demonstrated a statistically significant improvement in retinal reattachment rates (RR =1.36, 95%CI=1-1.84) and a reduction in reoperation rates (RR=0.23, 95% CI=0.07 -0.69) compared to the control group, while none of the other drugs had statistically significant results. Additionally, adjunctive therapy did not yield significant improvements in IOP, ERM, or macular edema, except for a reduction in macular edema associated with dexamethasone in one study. This systematic review and NMA indicate that most pharmacological agents could not significantly improve retinal reattachment, reduce PVR recurrence, or lower reoperation rates following RD surgery. 13-cis-RA was the only drug that showed a significant impact on lowering retinal detachment and reoperation rates. Further high-quality clinical trials are warranted to confirm these findings.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancing Ophthalmology With Large Language Models: Applications, Challenges, and Future Directions.

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-03-01 DOI: 10.1016/j.survophthal.2025.02.009

Qi Zhang, Shaopan Wang, Xu Wang, Changsheng Xu, Jiajun Liang, Zuguo Liu

引用次数: 0

The mirrored arterial dilemma.

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-02-28 DOI: 10.1016/j.survophthal.2025.02.006

Skenda Jean-Charles, Marissa K Shoji, Don O Kikkawa, M Tariq Bhatti

引用次数: 0

Social media in ophthalmology: A comprehensive literature review.

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-02-22 DOI: 10.1016/j.survophthal.2025.02.003

Jennifer K Dunnigan, Celeste Y Wang, Livia George, Virginia A Lee, Kevin E Lai, Andrew R Carey, Andrew G Lee

引用次数: 0

Clinical strategies to prevent recurrence of Herpes simplex and Herpes zoster following ocular surgery: A comprehensive review with practical guidelines.

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-02-15 DOI: 10.1016/j.survophthal.2025.02.002

Sadegh Ghafarian, Bijan Samavat, Karen Lee, Sima Sheikhghomi, Kasra Cheraghpour, Deepak Shukla, Ali R Djalilian, James Chodosh, Mohammad Soleimani

引用次数: 0

If at first you don't succeed, try, try again.

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-02-14 DOI: 10.1016/j.survophthal.2025.01.011

Kambiz Ameli, Jacqueline M Ihinger, Michael S Lee, Andrew R Carey

引用次数: 0

The applications of viscoelastic agents in vitreoretinal surgery.

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-02-12 DOI: 10.1016/j.survophthal.2025.02.001

Matteo Mario Carlà, Federico Giannuzzi, Francesco Boselli, Carlos Mateo, Tomaso Caporossi, Stanislao Rizzo

{"title":"The applications of viscoelastic agents in vitreoretinal surgery.","authors":"Matteo Mario Carlà, Federico Giannuzzi, Francesco Boselli, Carlos Mateo, Tomaso Caporossi, Stanislao Rizzo","doi":"10.1016/j.survophthal.2025.02.001","DOIUrl":"10.1016/j.survophthal.2025.02.001","url":null,"abstract":"The introduction of viscoelastics in human ocular surgery dates back to 1972.Subsequntly, several substances were proposed as adjuvants, particularly for cataract surgery; however, the rheologic properties of ophthalmic viscosurgical devices (OVDs), such as viscosity, pseudoplasticity, and coatability led to their employment also in vitreoretinal surgery. OVDs can be used to separate tissues and create space, to break adhesions, to allow space for surgical manipulation, and to contain hemorrhage by dampening capillary oozing. We focus on the principles and clinical results of several viscosurgery techniques, such as viscodissection and viscodelamination for the management of proliferative vitreoretinopathy and diabetic retinopathy and suprachoroidal buckling for primary retinal detachment. Furthermore, we analyze the techniques in which OVDs served as adjuvants in macular hole surgery, particularly in the handling of the internal limiting membrane, and as volumetric substances against hypotony. Finally, we analyze recent perspectives on vitreous humor biochemical features. Preclinical research led to the belief that hyaluronic acid-based hydrogels could become ideal vitreous substitutes, thanks to their viscoelasticity, porosity, optical properties, and biocompatibility; however, although promising, long-term toxicity issues have limited studies on human subjects.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacological associations of central serous chorioretinopathy: Looking beyond corticosteroids.

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-02-09 DOI: 10.1016/j.survophthal.2025.01.017

Manish Jain, Arthi Mohankumar, Jairo Torres, Hamad A Alkorbi

{"title":"Pharmacological associations of central serous chorioretinopathy: Looking beyond corticosteroids.","authors":"Manish Jain, Arthi Mohankumar, Jairo Torres, Hamad A Alkorbi","doi":"10.1016/j.survophthal.2025.01.017","DOIUrl":"10.1016/j.survophthal.2025.01.017","url":null,"abstract":"Central serous chorioretinopathy (CSCR) has multiple associations and risk factors. Of these, psychological stress, corticosteroid treatment, and specific personality traits are well recognized. Other drugs, such as sympathomimetic agents, psychotropic drugs and phosphodiesterase inhibitors, are frequently incriminated. Male preponderance and higher incidence among pregnant and menopausal women give credence to a role of gonadal hormones; however, the acceptance or rejection of the proposed role of other drugs remains challenging due to paucity of data resulting from low usage. Despite presence of multiple risk factors in several patients, a large proportion remains idiopathic. We reviewed all such drugs, including sympathomimetic drugs, psychotropic drugs and recreational agents, phosphodiesterase inhibitors, gonadal hormones and analogues, vasopressin, minoxidil, follistatin, fingolimod, topiramate, muscle relaxants, and vaccines. The mechanisms and adverse event profile of these drugs suggest multiple ways such as alteration of hypothalamic-pituitary-adrenal axis, cortisol surge, activation of sympathetic nervous system, nitric-oxide synthetase, proinflammatory cytokines, complement factor F, Cytochrome P450 3A4, voltage gated ion channels, connexins and neurotransmitters that eventually contribute to CSCR. A common denominator, however, is the systemic and choroidal hemodynamic changes. A detailed medication history can unravel the modifiable risk factors in idiopathic CSCR; this history must include drugs that alter the clearance of other drugs and hormones via the cytochrome P450-3A4 system.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ocular-induced abnormal head postures: A systematic review and analysis.

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-02-09 DOI: 10.1016/j.survophthal.2025.01.016

Saja Al-Dabet, Sherzod Turaev, Nazar Zaki

{"title":"Ocular-induced abnormal head postures: A systematic review and analysis.","authors":"Saja Al-Dabet, Sherzod Turaev, Nazar Zaki","doi":"10.1016/j.survophthal.2025.01.016","DOIUrl":"10.1016/j.survophthal.2025.01.016","url":null,"abstract":"Abnormal head postures (AHPs) are frequently adopted as compensatory mechanisms by individuals affected by various ocular diseases to optimize the utilization of their visual field or alleviate symptoms such as diplopia. We review the causal relationship between ocular diseases and the resulting AHPs. An extensive literature search was conducted to identify and summarize relevant medical studies providing evidence of AHPs in patients diagnosed with conditions like Duane retraction syndrome, Brown syndrome, superior oblique palsy, and other ocular disorders. The analysis explores the proportion of AHP types (head tilt, turn, chin-up/down) and the frequency distribution of ocular conditions for each studied disease. In addition, the degrees of ocular misalignment (hypertropia, hypotropia, esotropia, exotropia) associated with specific AHP manifestations are quantified. Key properties of ocular misalignment and AHPs across different diseases are examined, and Cramer's V statistical measure is employed to assess the association between diseases, AHPs, and ocular misalignment. The findings highlight the need for comprehensive datasets encompassing diverse ocular diseases to support the development of robust artificial intelligence models capable of accurately diagnosing AHPs. This study contributes an in-depth understanding of the mechanisms underlying AHPs and provides a foundation for advancing diagnostic and rehabilitation strategies in vision sciences.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reply: A major review on punctal stenosis: Updated anatomy, epidemiology, etiopathology, and clinical presentation

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-02-06 DOI: 10.1016/j.survophthal.2025.01.014

Hatem A. Tawfik MD, Mohammad Javed Ali MD, PhD, FRCS

引用次数: 0