Survey of ophthalmology最新文献

{"title":"Efficacy and complications of microcatheter-assisted minimally invasive glaucoma surgery for open-angle glaucoma: A systematic review and network meta-analysis.","authors":"Luyi Han, Yingyan Mao, Qing Sang, Yue Wan, Ningli Wang","doi":"10.1016/j.survophthal.2025.06.001","DOIUrl":"https://doi.org/10.1016/j.survophthal.2025.06.001","url":null,"abstract":"<p><p>Microcatheter-assisted minimally invasive glaucoma surgery (MIGS) procedures is increasingly being used as an alternative to trabeculectomy combined with mitomycin C (MMC Trab) for controlling intraocular pressure (IOP) in open-angle glaucoma (OAG), but there are no head-to-head trials comparing diNerent microcatheter-assisted MIGS procedures and MMC Trab. We evaluate the relative efficacy and safety of microcatheter-assisted MIGS procedures, including microcatheter-assisted trabeculotomy (MAT), gonioscopy-assisted transluminal trabeculotomy (GATT), Ab-interno Canaloplasty(ABiC), ab-externo canaloplasty(ABeC), and trabeculotome tunnelling trabeculoplasty surgery (3T), through a network meta-analysis (NMA), with a focus on their priority ranking in IOP reduction and medication use. MMC Trab was included as the reference standard to contextualize the performance of emerging microcatheter-assisted techniques. We conducted searches for studies published between 01/01/2009 and 16/10/2024, with no restrictions regarding participant age or language of publication. The conduct of review followed a protocol registered on PROSPERO (CRD42024557637). PRISMA guidelines were followed for reporting. For observational studies and RCTs, use the Newcastle-Ottawa Quality Assessment Scale (NOS) and Cochrane Risk of Bias tool for Randomized Trials (RoB 2) respectively for evaluation. Data extraction was conducted by 2 independent reviewers, and then checked and adjudicated by a third reviewer. The mean differences for continuous variables, risk ratios for binary variables, 95% credible intervals (CI), and ranks of interventions were estimated. The outcomes examined included the reduction (%) in IOP and the reduction in medication used from baseline at 3 months and 1 year. We also extracted adverse events reported, such as hyphema, IOP spike and hypotony. Sixteen studies (a total of 1081 eyes) were included in the NMA. For efficacy at one year, MAT showed no significant difference compared to MMC Trab in both percent reduction in IOP (MD -4.78% (95%CI -3.01% to 3.45%), SUCRA 65.7) and reduction in medication used (MD 0.18 (95%CI -0.19 to 0.54%), SUCRA 97.4), GATT (MD -7.20% (95%CI -13.73% to -0.67%), SUCRA 53.1%) showed no significant difference from MMC Trab in terms of reduction in medication use. For complications within three months postoperatively, all microcatheter-assisted MIGS procedures showed no significant difference versus MMC Trab in terms of postoperative IOP spike. GATT (RR 0.06 (95%CI, 0.01 to 0.35), SUCRA 87%) and ABeC (RR 0.3 (95%CI, 0.1 to 2.92), SUCRA 44.3%) were associated with a lower risk of hypotony compared to MMC Trab. All microcatheter-assisted MIGS procedures were associated with a higher risk of hyphema. Compared to MMC Trab, MAT showed no significant difference in efficacy at one year postoperatively, and certain microcatheter-assisted MIGS procedures have specific advantages over MMC Trab in terms of postoperative complications.</p","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144249678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathophysiology of intraoperative floppy iris syndrome: An unsettled debate.","authors":"Yingchun Shen, Rachel Frauches, Jingyu Zhao, Chien-Hui Lo, Ke Ning, Siyu Chen, Zhiquan Liu, Fan Zhang, Yang Sun","doi":"10.1016/j.survophthal.2025.06.002","DOIUrl":"https://doi.org/10.1016/j.survophthal.2025.06.002","url":null,"abstract":"<p><p>Intraoperative floppy iris syndrome (IFIS)--characterized by iris blowing, prolapse, and progressive miosis during phacoemulsification surgery--poses significant challenges for eye surgeons. Despite being described almost 2 decades ago, its pathophysiology remains unclear. Initially, IFIS was thought to be a result of sympathetic signal blockage in the iris dilator muscle, since α-blockers such as tamsulosin were found to be a strong predisposing factor; however, many IFIS cases occur even in patients who discontinued α-blockers prior to cataract surgery. Several potential mechanisms through which α-blockers induces chronic changes in the iris - iris dilator atrophy, drug-melanin interaction, and loss of vascular tone - have been proposed as possible mechanisms. We address the prevailing theories on α-receptor-dependent mechanisms for IFIS and the current prophylactic measures undertaken to prevent IFIS-associated intraocular complications.</p>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optic disc drusen-associated neovascularization: A systematic review.","authors":"Anas Alkhabaz, Rishita Pujari, Yulan Ren, Stephen J Smith, Yaping Joyce Liao","doi":"10.1016/j.survophthal.2025.05.010","DOIUrl":"10.1016/j.survophthal.2025.05.010","url":null,"abstract":"<p><p>We have integrated current evidence of visual outcomes in optic disc drusen-associated choroidal neovascularization (ODD-CNV). We systematically reviewed all published ODD-CNV cases from 1974 to 2024 using three databases (PubMed, EMBASE, and Web of Science). Only studies reporting baseline visual acuity, follow-up visual acuity, and an intervention were included. Methodological quality was assessed using a standardized tool for case reports. Seventy-four eyes (65 patients) were identified from 48 eligible articles. The median age of the subjects was 13 years (range: 3-75), and 63.5 % were females. CNVs were mainly peripapillary, with 45.7 % of them progressing into the macula. On average, the eyes had a follow-up period of 21.5 months. Overall, treatment (of any type) showed better outcomes (0.53 LogMAR improvement, > 3 lines on Snellen chart) compared to observation only (0.09 LogMAR improvement). Anti-vascular endotheial growth factor (VEGF) injections and laser photocoagulation, the most frequently used interventions, showed 0.62 and 0.19 LogMAR improvement, respectively; however, the difference was not statistically significant (p = 0.05398). Among 24 pediatric eyes, anti-VEGF showed 0.71 LogMAR improvement with minimal side effects and recurrence in one eye only. When stratified by age, pediatric patients experienced a greater LogMAR improvement compared to adults, even when adjusting for anti-VEGF treatment (p = 0.0279). Our findings highlight the importance of intervention in ODD-CNV patients, particularly in the younger population, as they are more responsive to treatment. Anti-VEGF demonstrates great efficacy and safety profile in the pediatric population.</p>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of social determinants of health on causes of ophthalmic trauma: A narrative review.","authors":"Malik Muhammad Hamza Khan, Anam Akhlaq, Muhammad Jehanzeb Khan, Muhammad Ali, Emily Joseph, Grant A Justin, Fasika Woreta","doi":"10.1016/j.survophthal.2025.05.012","DOIUrl":"10.1016/j.survophthal.2025.05.012","url":null,"abstract":"<p><p>Ophthalmic trauma (OT) is a leading cause of monocular vision loss that preferentially affects certain populations. In this narrative review, we aim to discuss the impact of social determinants of health (SDOH) on the prevalence and outcomes of OT. We conducted a literature search to identify studies published between 2019 and 2024 that discuss the impact of SDOH on OT. A total of 92 studies were included. Overall, males, particularly those of younger and working age groups, are most commonly affected with OT, with assault-, firearm-, and occupation-related injuries being the most frequent. In comparison, falls and intimate partner violence are the most common causes of OT in women. Children are more prone to toys, sports, and firework-related injuries, while falls represent the leading cause in elderly and frequently results in open globe injury. Black and Hispanic individuals suffer disproportionately from assault- and firearm-related injuries. Unemployed individuals, those of rural residence or of low socioeconomic status have higher rates of OT. Our review underscores the impact of demographic, social, and economic factors on the risk and outcomes of OT and its subtypes. Only by understanding the patterns, targeted interventions and policy changes can be undertaken to address these disparities.</p>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness and safety of anti-vascular endothelial growth factor therapies for macular edema in retinal vein occlusion: A systematic review and network meta-analysis of randomized controlled trials.","authors":"Kai-Yang Chen, Hoi-Chun Chan, Chi-Ming Chan","doi":"10.1016/j.survophthal.2025.05.008","DOIUrl":"10.1016/j.survophthal.2025.05.008","url":null,"abstract":"<p><p>We evaluated the efficacy and safety of anti-vascular endothelial growth factor (anti-VEGF) therapies for macular edema (ME) secondary to retinal vein occlusion (RVO), a leading cause of vision loss. A comprehensive search of 6 databases identified 17 RCTs involving 4272 eyes. Eligible studies reported outcomes such as visual acuity, ETDRS letter scores, central retinal thickness (CRT), and adverse events, with follow-up of at least 6 months. Anti-VEGF therapy showed significant efficacy, with a pooled mean difference (MD) of 15.14 ETDRS letters (95 % CI: 14.24-16.03, p < 0.001). Over 12 months, patients were 2.87 times more likely to achieve gains of > 15 ETDRS letters (OR 2.87, 95 % CI: 2.21-3.72). CRT decreased by MD of -350 µm (95 % CI: -0.363 to -0.338, p < 0.001). Safety analysis revealed reduced treatment-related adverse events (TRAEs) (OR 0.88, p = 0.035) with no significant systemic risks. Intraocular pressure elevation (OR 1.924, p < 0.001) warrants monitoring. Subgroup analysis highlighted faricimab as most effective, with aflibercept, ranibizumab, and bevacizumab providing substantial benefits. Anti-VEGF therapy is an effective, safe cornerstone for managing ME in RVO. Further research should explore biomarkers and combination treatments to refine therapeutic approaches.</p>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catching up with the Planet of the Apex.","authors":"Priya Bahra, Amy Tsoi, Hannah Kamgarpour, Lloyd Kopecny, Ian C Francis","doi":"10.1016/j.survophthal.2025.05.007","DOIUrl":"https://doi.org/10.1016/j.survophthal.2025.05.007","url":null,"abstract":"","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clarification of insulin concentration reporting in Krolo and coworkers' review.","authors":"Sara Ben Addou Idrissi, Hassan Moutei, Ahmed Bennis, Fouad Chraibi, Meriem Abdellaoui, Idriss Benatiya Andaloussi","doi":"10.1016/j.survophthal.2025.05.006","DOIUrl":"10.1016/j.survophthal.2025.05.006","url":null,"abstract":"","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Authors' response to the letter of Ben Addou Idrissi and colleagues: \"Clarification of insulin concentration reporting in Krolo and coworkers' review\".","authors":"Iva Krolo, Joséphine Behaegel, Karolien Termote, Barbara de Bruyn, Manon De Schepper, Silke Oellerich, Sorcha Ní Dhubhghaill","doi":"10.1016/j.survophthal.2025.05.009","DOIUrl":"10.1016/j.survophthal.2025.05.009","url":null,"abstract":"","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144133066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to \"Catching up with the planet of the apex\".","authors":"Francesco Pellegrini, Maria Basciu, Rod Foroozan","doi":"10.1016/j.survophthal.2025.05.011","DOIUrl":"10.1016/j.survophthal.2025.05.011","url":null,"abstract":"","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144133071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Choroidal hypopigmented lesions: A review.","authors":"Elham Rahmanipour, Elham Sadeghi, Supriya Arora, Mohammad Ghorbani, Mehrnoosh Maalhagh, Ramesh Venkatesh, Jay Chhablani","doi":"10.1016/j.survophthal.2025.05.002","DOIUrl":"10.1016/j.survophthal.2025.05.002","url":null,"abstract":"<p><p>Choroidal hypopigmented lesions (CHLs) represent significant diagnostic and therapeutic challenges due to their diverse and complex etiologies, including neoplastic, infectious, and inflammatory origins. Accurately differentiating between benign lesions with good prognoses and malignant or life-threatening conditions is crucial in directing the appropriate management and avoiding unnecessary invasive interventions. We integrate the latest research and clinical guidelines on advanced multimodal imaging modalities, emphasizing their comparative diagnostic value across varied etiologies of CHLs. In contrast to prior studies, we comprehensively evaluates the clinical implications of these techniques in accurately differentiating between benign from malignant choroidal lesions. Emphasis is placed on the role of advanced imaging modalities, including swept-source optical coherence tomography, B-scan ultrasound, fundus autofluorescence, fluorescein angiography, and indocyanine green angiography, in enhancing diagnostic precision. These technologies have substantially increased the capability to distinguish between lesion types, improving diagnostic accuracy and giving more targeted therapeutic strategies.</p>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}