Survey of ophthalmology最新文献

{"title":"Corrigendum to \"Iris melanoma: Prognostication for metastasis\"[Survey Ophthalmol 68 (2023) 957-963].","authors":"Alexander Melendez-Moreno, Yağmur Seda Yeşiltaş, N P Jacquelyn Wrenn, Arun D Singh","doi":"10.1016/j.survophthal.2025.06.010","DOIUrl":"https://doi.org/10.1016/j.survophthal.2025.06.010","url":null,"abstract":"","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144554991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinopathy of prematurity training and education: A systematic review.","authors":"Amy Song, Esther Lee, Susan R Ostmo, Karyn E Jonas, Margaret A Chervinko, Aaron S Coyner, J Peter Campbell, R V Paul Chan","doi":"10.1016/j.survophthal.2025.06.007","DOIUrl":"10.1016/j.survophthal.2025.06.007","url":null,"abstract":"<p><p>Globally, management of retinopathy of prematurity (ROP) is limited by a shortage of ophthalmologists who are adequately trained in identifying disease due to limited exposure in ophthalmology residencies and fellowships. We review the current state of ROP education and training and propose strategies to addressing the ROP workforce shortage. Adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a systematic review was performed using PubMed, Embase, and SCOPUS. Terms that were used in the database searches include telemedicine, tele-education, tele-health, retinopathy of prematurity, artificial intelligence, medical education, training. Advancements in tele-education and artificial intelligence have paved the way for increased accessibility to ROP training, particularly in low- and middle-income countries; however, to ensure that these new modalities are effective in clinical practice and training, ophthalmology residency and fellowship programs must implement relevant education and training into their curricula.</p>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in diagnosing and treating giant cell arteritis: New hope for arteritic anterior ischemic optic neuropathy.","authors":"Leon von der Emde, Simon M Petzinna, Martina C Herwig-Carl, Maike S Adamson, Claus-Juergen Bauer, Julia Esser, Alexander Isaak, Katharina Wall, Jan H Terheyden, Frank G Holz, Valentin S Schäfer, Thomas Ach","doi":"10.1016/j.survophthal.2025.06.009","DOIUrl":"10.1016/j.survophthal.2025.06.009","url":null,"abstract":"<p><p>Giant cell arteritis (GCA) is an autoimmune disease of medium and large sized vessels. It is the most prevalent form of primary vasculitis in the western world. Vascular inflammation in GCA can lead to vascular occlusion. Severe neuro-ophthalmological complications, such as arteritic anterior ischemic optic neuropathy (aAION), may present with sudden partial or complete vision loss or diplopia. Visual impairment is often refractory to corticosteroid therapy, underscoring the critical importance of early diagnosis. Delayed diagnosis and initiation of high-dose corticosteroids can lead to contralateral eye involvement and bilateral irreversible vision loss. Recent advances in expedited diagnostics have significantly improved outcomes in GCA patients, particularly by reducing ischemic neuro-ophthalmological events. Thus, a key factor has been the introduction of Fast-Track Clinics (FTCs) that have successfully decreased the incidence of permanent blindness in GCA patients. In these clinics, imaging modalities such as vascular ultrasound, magnetic resonance imaging (MRI), and positron emission tomography-computed tomography (PET/CT) play a critical role in both diagnosis and disease monitoring, enabling timely and accurate intervention. On the therapeutic front, cytokine-specific inhibitors have improved GCA management, enhancing remission rates and reducing glucocorticoid use. Tocilizumab, an IL-6 receptor (IL-6R) inhibitor, has become a cornerstone of GCA treatment; however, since some patients do not respond to IL-6R inhibition, ongoing research is exploring alternative disease-modifying therapies. These new approaches aim to reduce glucocorticoid dependency, mitigate side effects, enhance visual outcomes, and improve patient outcomes, highlighting a shift towards more individualized treatment approaches.</p>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence in the prediction of glaucoma development and progression: A systematic review.","authors":"Wei Yun Lily Yang, Hon Jen Wong, Clarissa Elysia Fu, William Rojas-Carabali, Rupesh Agrawal, Bryan Chin Hou Ang","doi":"10.1016/j.survophthal.2025.06.006","DOIUrl":"10.1016/j.survophthal.2025.06.006","url":null,"abstract":"<p><p>Glaucoma remains the leading cause of irreversible blindness worldwide. Artificial intelligence (AI) may help enhance predict glaucoma development and progression. We provide a consolidated review of AI usage in predicting the (a) development of glaucoma in glaucoma suspects and normal patients, (b) progression of existing glaucoma, and (c) progression towards the occurrence of surgery. We searched PubMed, EMBASE, Scopus, ScienceDirect, and CENTRAL for observational studies and clinical trials comparing different AI models or AI models versus physician performance published in English from Aug 17, 2013, to Dec 5, 2024. We excluded studies describing AI models that required physician assistance or were designed to diagnose glaucoma. A total of 44 studies (7 studies for the development of glaucoma in glaucoma suspects and normal patients, 30 studies for progression of existing glaucoma, and 7 studies for progression towards the occurrence of surgery) were included. AI demonstrates favorable performance in predicting glaucoma development in glaucoma suspects and normal patients, as well as glaucomatous progression in diagnosed patients. There is significant potential for AI to aid the surveillance of glaucoma in those without a prior history. Moreover, its ability to predict future glaucomatous progression in diagnosed patients could improve systems-of-care targeted at halting disease progression.</p>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brillouin microscopy for focal biomechanical measurements in normal and keratoconic corneas: A narrative review.","authors":"Bassel Hammoud, Justin S Schumacher, Hongyuan Zhang, Barbara A L Dutra, Bianca N Susanna, Giuliano Scarcelli, J Bradley Randleman","doi":"10.1016/j.survophthal.2025.06.004","DOIUrl":"10.1016/j.survophthal.2025.06.004","url":null,"abstract":"<p><p>Corneal mechanical weakness is widely recognized as the root cause of keratoconus and a primary driver for undesirable refractive surgery outcomes. Theory, finite element modeling, and initial data predict that focal rather than generalized weakening precipitates corneal mechanical decompensation. Direct, 3-dimensionally (3-D) localized in vivo corneal mechanical measurements thus have the potential to revolutionize keratoconus management and the surgical correction of myopia. Collagen microarchitecture and mechanical profiles in normal and keratoconic corneas have been evaluated ex vivo, but significant gaps remain in our understanding of the earliest subclinical manifestations that can eventually lead to clinical disease. Nonperturbative Brillouin microscopy has emerged as a novel approach for measuring corneal mechanics by analyzing Brillouin light scattering, which encodes the corneal elastic modulus (longitudinal modulus). Early ex vivo works demonstrated the technique's ability to identify depth-dependent (axial) anisotropy in the normal cornea, focal weakening in the keratoconic cornea, and stiffening after corneal cross-linking. Recent advances using motion-tracking Brillouin imaging, which employs optical coherence tomography and eye tracking to facilitate 3-D signal localization, have provided novel insights into keratoconus at the subclinical stage. Locally reduced Brillouin shift values in the anterior cornea have differentiated subclinical keratoconic cornea from normal controls and outperformed current clinical standard morphologic evaluation using Scheimpflug technology. Herein, we highlight the development of Brillouin microscopy for in vivo corneal analysis, current imaging advances and technological limitations, and future directions for in vivo analysis of subclinical keratoconus to advance our understanding of keratoconus diagnosis, disease evolution, and management.</p>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144294955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inherited retinal disease in global Indigenous populations: A scoping review.","authors":"Emma C Tovey Crutchfield, Andrea L Vincent, Mitchell D Anjou, Hugh R Taylor, Shaun Tatipata, Krystal S Tsosie, Livia S Carvalho, Lauren N Ayton, Alexis Ceecee Britten-Jones","doi":"10.1016/j.survophthal.2025.06.005","DOIUrl":"10.1016/j.survophthal.2025.06.005","url":null,"abstract":"<p><p>Accurate diagnosis is essential for accessing emerging gene-targeted treatments for inherited retinal diseases (IRDs), but many minoritised communities face additional barriers to diagnosis. This scoping review synthesised clinical studies on the prevalence and diagnosis of IRDs among Indigenous Peoples worldwide. Medline, Embase, Global Health, Informit and CINAHL were searched on December 4, 2023. We included articles reporting Indigenous Peoples with IRDs from all global regions published between 1974 and 2023; 73 studies (581 cases) of IRDs in Indigenous Peoples from 24 countries were included, mostly reporting participants indigenous to the Middle East (34 %), Oceania (27 %) and North America (23 %). Studies of specific IRD cases showed geographical or cultural group associations, such as rod-cone dystrophy among the Diné (Navajo Nation) or Bardet-Biedl syndrome in Bedouin populations of the Middle East. With dedicated programs, population-specific IRD gene variants in the Middle Eastern Bedouin populations, New Zealand Māori and other Pacific peoples are the most well-characterised, and this has enabled improved diagnostic approaches. There is limited knowledge of the relative prevalence and support needs for IRDs among most other global Indigenous groups. Engagement, co-designed approaches and collective efforts, including raising awareness, may address challenges limiting equitable access to IRD diagnosis for Indigenous Peoples, facilitating access to emerging treatments.</p>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144294956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of neighborhood-level deprivation on glaucoma prevalence and treatment: A review of the literature.","authors":"Joshua Woo, Sakshi Chopra, Keke Liu, Brandi Tuttle, Kelly W Muir","doi":"10.1016/j.survophthal.2025.06.003","DOIUrl":"10.1016/j.survophthal.2025.06.003","url":null,"abstract":"<p><p>We summarize the existing literature describing the associations between neighborhood-level socioeconomic indices and various glaucoma-related health outcomes. Glaucoma remains one of the leading causes of blindness worldwide, and while risk factors have been identified, there remains an incomplete understanding of the relationship between glaucoma and social determinants of health, especially at the neighborhood-level. This is particularly clinically relevant for the treatment of glaucoma due to the importance of early detection, access to specialty care, and long-term medication adherence in slowing disease progression. A review of the literature was completed in MEDLINE (Ovid) and Scopus (Elsevier) from inception to December 4, 2023, of publications describing an association between a neighborhood-level index and a glaucoma-related outcome, yielding 15 studies. A manual networking search was performed on March 1, 2024, and an additional search update was completed on September 19, 2024, resulting in the inclusion of 7 additional studies. After a comprehensive search and full-text review, 22 papers were included in our final analysis. Across all studies encompassing over 60 million total records, the mean patient age was 66.5 years, with 47.4 % being male. The most utilized neighborhood indices were the Social Vulnerability Index (SVI) and Index of Multiple Deprivation (IMD), and nearly all studies were based in either the United States or Europe. The majority of studies found an association between socioeconomic deprivation and 1) higher prevalence of glaucoma, 2) greater visual field loss at initial presentation, or 3) reduced access or delays associated with glaucoma treatment. Of these relationships, the strongest evidence was found linking neighborhood-level deprivation to increased glaucoma prevalence. Our review provides useful insight about the role of neighborhood-level socioeconomic factors and glaucoma, particularly by identifying important relationships that may otherwise remain unnoticed with aggregate, country-level data. The disparities involving glaucoma prevalence, presentation and treatment, especially in underresourced communities, indicate a vital need for earlier, more accessible intervention and greater investment into preventive care. Future studies might look to analyze prospectively patient outcomes and isolate the biggest drivers of disparities in health outcomes at the neighborhood-level, with significant clinical implications.</p>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144286552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and complications of microcatheter-assisted minimally invasive glaucoma surgery for open-angle glaucoma: A systematic review and network meta-analysis.","authors":"Luyi Han, Yingyan Mao, Qing Sang, Yue Wan, Ningli Wang","doi":"10.1016/j.survophthal.2025.06.001","DOIUrl":"10.1016/j.survophthal.2025.06.001","url":null,"abstract":"<p><p>Microcatheter-assisted minimally invasive glaucoma surgery (MIGS) procedures are increasingly being used as an alternative to trabeculectomy combined with mitomycin C (MMC Trab) for controlling intraocular pressure (IOP) in open-angle glaucoma (OAG), but there are no head-to-head trials comparing different microcatheter-assisted MIGS procedures and MMC Trab. We evaluate the relative efficacy and safety of microcatheter-assisted MIGS procedures, including microcatheter-assisted trabeculotomy (MAT), gonioscopy-assisted transluminal trabeculotomy (GATT), Ab-interno Canaloplasty(ABiC), ab externo canaloplasty(ABeC), and trabeculotome tunnelling trabeculoplasty surgery (3 T), through a network meta-analysis with a focus on their priority ranking in IOP reduction and medication use. MMC Trab was included as the reference standard to contextualize the performance of emerging microcatheter-assisted techniques. We conducted searches for studies published between 01/01/2009 and 16/10/2024, with no restrictions regarding participant age or language of publication. We followed a protocol registered on PROSPERO (CRD42024557637). PRISMA guidelines were followed for reporting. For observational studies and randomized clinical trials, use the Newcastle-Ottawa Quality Assessment Scale and Cochrane Risk of Bias tool for Randomized Trials (RoB 2) respectively for evaluation. Data extraction was conducted by 2 independent reviewers, and then checked and adjudicated by a third reviewer. The mean differences for continuous variables, risk ratios for binary variables, 95 % credible intervals, and ranks of interventions were estimated. The outcomes examined included the reduction (%) in IOP and the reduction in medication used from baseline at 3 months and 1 year. We also extracted adverse events reported, such as hyphema, IOP spike and hypotony. Sixteen studies (a total of 1081 eyes) were included in the NMA. For efficacy at 1 year, MAT showed no significant difference compared to MMC Trab in both percent reduction in IOP (MD -4.78 % (95 %CI -3.01-3.45 %), SUCRA 65.7) and reduction in medication used (MD 0.18 (95 %CI -0.19-0.54 %), SUCRA 97.4), GATT (MD -7.20 % (95 %CI -13.73 % to -0.67 %), SUCRA 53.1 %) showed no significant difference from MMC Trab in terms of reduction in medication use. For complications within 3 months postoperatively, all microcatheter-assisted MIGS procedures showed no significant difference versus MMC Trab in terms of postoperative IOP spike. GATT (RR 0.06 (95 %CI, 0.01-0.35), SUCRA 87 %) and ABeC (RR 0.3 (95 %CI, 0.1-2.92), SUCRA 44.3 %) were associated with a lower risk of hypotony compared to MMC Trab. All microcatheter-assisted MIGS procedures were associated with a higher risk of hyphema. Compared to MMC Trab, MAT showed no significant difference in efficacy at 1 year postoperatively, and certain microcatheter-assisted MIGS procedures have specific advantages over MMC Trab in terms of postoperative complications.</p>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144249678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathophysiology of intraoperative floppy iris syndrome: An unsettled debate.","authors":"Yingchun Shen, Rachel Frauches, Jingyu Zhao, Chien-Hui Lo, Ke Ning, Siyu Chen, Zhiquan Liu, Fan Zhang, Yang Sun","doi":"10.1016/j.survophthal.2025.06.002","DOIUrl":"10.1016/j.survophthal.2025.06.002","url":null,"abstract":"<p><p>Intraoperative floppy iris syndrome (IFIS)--characterized by iris blowing, prolapse, and progressive miosis during phacoemulsification surgery--poses significant challenges for eye surgeons. Despite being described almost 2 decades ago, its pathophysiology remains unclear. Initially, IFIS was thought to be a result of sympathetic signal blockage in the iris dilator muscle, since α-blockers such as tamsulosin were found to be a strong predisposing factor; however, many IFIS cases occur even in patients who discontinued α-blockers prior to cataract surgery. Several potential mechanisms through which α-blockers induces chronic changes in the iris - iris dilator atrophy, drug-melanin interaction, and loss of vascular tone - have been proposed as possible mechanisms. We address the prevailing theories on α-receptor-dependent mechanisms for IFIS and the current prophylactic measures undertaken to prevent IFIS-associated intraocular complications.</p>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optic disc drusen-associated neovascularization: A systematic review.","authors":"Anas Alkhabaz, Rishita Pujari, Yulan Ren, Stephen J Smith, Yaping Joyce Liao","doi":"10.1016/j.survophthal.2025.05.010","DOIUrl":"10.1016/j.survophthal.2025.05.010","url":null,"abstract":"<p><p>We have integrated current evidence of visual outcomes in optic disc drusen-associated choroidal neovascularization (ODD-CNV). We systematically reviewed all published ODD-CNV cases from 1974 to 2024 using three databases (PubMed, EMBASE, and Web of Science). Only studies reporting baseline visual acuity, follow-up visual acuity, and an intervention were included. Methodological quality was assessed using a standardized tool for case reports. Seventy-four eyes (65 patients) were identified from 48 eligible articles. The median age of the subjects was 13 years (range: 3-75), and 63.5 % were females. CNVs were mainly peripapillary, with 45.7 % of them progressing into the macula. On average, the eyes had a follow-up period of 21.5 months. Overall, treatment (of any type) showed better outcomes (0.53 LogMAR improvement, > 3 lines on Snellen chart) compared to observation only (0.09 LogMAR improvement). Anti-vascular endotheial growth factor (VEGF) injections and laser photocoagulation, the most frequently used interventions, showed 0.62 and 0.19 LogMAR improvement, respectively; however, the difference was not statistically significant (p = 0.05398). Among 24 pediatric eyes, anti-VEGF showed 0.71 LogMAR improvement with minimal side effects and recurrence in one eye only. When stratified by age, pediatric patients experienced a greater LogMAR improvement compared to adults, even when adjusting for anti-VEGF treatment (p = 0.0279). Our findings highlight the importance of intervention in ODD-CNV patients, particularly in the younger population, as they are more responsive to treatment. Anti-VEGF demonstrates great efficacy and safety profile in the pediatric population.</p>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}