Survey of ophthalmology最新文献_第2页

Effectiveness and safety of anti-vascular endothelial growth factor therapies for macular edema in retinal vein occlusion: A systematic review and network meta-analysis of randomized controlled trials. 抗vegf治疗视网膜静脉闭塞黄斑水肿的有效性和安全性：随机对照试验的系统回顾和荟萃分析。

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-05-24 DOI: 10.1016/j.survophthal.2025.05.008

Kai-Yang Chen, Hoi-Chun Chan, Chi-Ming Chan

{"title":"Effectiveness and safety of anti-vascular endothelial growth factor therapies for macular edema in retinal vein occlusion: A systematic review and network meta-analysis of randomized controlled trials.","authors":"Kai-Yang Chen, Hoi-Chun Chan, Chi-Ming Chan","doi":"10.1016/j.survophthal.2025.05.008","DOIUrl":"10.1016/j.survophthal.2025.05.008","url":null,"abstract":"We evaluated the efficacy and safety of anti-vascular endothelial growth factor (anti-VEGF) therapies for macular edema (ME) secondary to retinal vein occlusion (RVO), a leading cause of vision loss. A comprehensive search of 6 databases identified 17 RCTs involving 4272 eyes. Eligible studies reported outcomes such as visual acuity, ETDRS letter scores, central retinal thickness (CRT), and adverse events, with follow-up of at least 6 months. Anti-VEGF therapy showed significant efficacy, with a pooled mean difference (MD) of 15.14 ETDRS letters (95 % CI: 14.24-16.03, p < 0.001). Over 12 months, patients were 2.87 times more likely to achieve gains of > 15 ETDRS letters (OR 2.87, 95 % CI: 2.21-3.72). CRT decreased by MD of -350 µm (95 % CI: -0.363 to -0.338, p < 0.001). Safety analysis revealed reduced treatment-related adverse events (TRAEs) (OR 0.88, p = 0.035) with no significant systemic risks. Intraocular pressure elevation (OR 1.924, p < 0.001) warrants monitoring. Subgroup analysis highlighted faricimab as most effective, with aflibercept, ranibizumab, and bevacizumab providing substantial benefits. Anti-VEGF therapy is an effective, safe cornerstone for managing ME in RVO. Further research should explore biomarkers and combination treatments to refine therapeutic approaches.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Catching up with the Planet of the Apex. 赶上顶点星球的进度。

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-05-23 DOI: 10.1016/j.survophthal.2025.05.007

Priya Bahra, Amy Tsoi, Hannah Kamgarpour, Lloyd Kopecny, Ian C Francis

引用次数: 0

Clarification of insulin concentration reporting in Krolo and coworkers' review. Krolo等人综述中胰岛素浓度报告的澄清。

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-05-22 DOI: 10.1016/j.survophthal.2025.05.006

Sara Ben Addou Idrissi, Hassan Moutei, Ahmed Bennis, Fouad Chraibi, Meriem Abdellaoui, Idriss Benatiya Andaloussi

引用次数: 0

Authors' response to the letter of Ben Addou Idrissi and colleagues: "Clarification of insulin concentration reporting in Krolo and coworkers' review". 作者对Ben Addou Idrissi等人的信的回应：“Krolo等人综述中胰岛素浓度报告的澄清”。

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-05-21 DOI: 10.1016/j.survophthal.2025.05.009

Iva Krolo, Joséphine Behaegel, Karolien Termote, Barbara de Bruyn, Manon De Schepper, Silke Oellerich, Sorcha Ní Dhubhghaill

引用次数: 0

Reply to "Catching up with the planet of the apex". 回复Priya Bahra等人的“赶上顶点星球”。

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-05-21 DOI: 10.1016/j.survophthal.2025.05.011

Francesco Pellegrini, Maria Basciu, Rod Foroozan

引用次数: 0

Choroidal hypopigmented lesions: A review. 脉络膜低色素病变：综述。

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-05-14 DOI: 10.1016/j.survophthal.2025.05.002

Elham Rahmanipour, Elham Sadeghi, Supriya Arora, Mohammad Ghorbani, Mehrnoosh Maalhagh, Ramesh Venkatesh, Jay Chhablani

{"title":"Choroidal hypopigmented lesions: A review.","authors":"Elham Rahmanipour, Elham Sadeghi, Supriya Arora, Mohammad Ghorbani, Mehrnoosh Maalhagh, Ramesh Venkatesh, Jay Chhablani","doi":"10.1016/j.survophthal.2025.05.002","DOIUrl":"10.1016/j.survophthal.2025.05.002","url":null,"abstract":"Choroidal hypopigmented lesions (CHLs) represent significant diagnostic and therapeutic challenges due to their diverse and complex etiologies, including neoplastic, infectious, and inflammatory origins. Accurately differentiating between benign lesions with good prognoses and malignant or life-threatening conditions is crucial in directing the appropriate management and avoiding unnecessary invasive interventions. We integrate the latest research and clinical guidelines on advanced multimodal imaging modalities, emphasizing their comparative diagnostic value across varied etiologies of CHLs. In contrast to prior studies, we comprehensively evaluates the clinical implications of these techniques in accurately differentiating between benign from malignant choroidal lesions. Emphasis is placed on the role of advanced imaging modalities, including swept-source optical coherence tomography, B-scan ultrasound, fundus autofluorescence, fluorescein angiography, and indocyanine green angiography, in enhancing diagnostic precision. These technologies have substantially increased the capability to distinguish between lesion types, improving diagnostic accuracy and giving more targeted therapeutic strategies.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Blow. 打击。

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-05-14 DOI: 10.1016/j.survophthal.2025.05.004

M Tariq Bhatti, Jeffrey G Moore, Thomas N Hwang, Jurij R Bilyk

{"title":"Blow.","authors":"M Tariq Bhatti, Jeffrey G Moore, Thomas N Hwang, Jurij R Bilyk","doi":"10.1016/j.survophthal.2025.05.004","DOIUrl":"10.1016/j.survophthal.2025.05.004","url":null,"abstract":"A 59-year-old woman presented with right periorbital frontal headache and vertical binocular diplopia. Computed tomography (CT) angiography of the head and neck with contrast was negative. C-reactive protein was 7.3 mg/dL (normal, <0.9 mg/dL) and erythrocyte sedimentation was 79 mm/hr. Despite a negative temporal artery biopsy, she was treated for biopsy-negative giant cell arteritis. Symptoms worsened over time. A review of the initial CT demonstrated paranasal sinus disease and a mass in the right medial orbit with disruption of the medial orbital wall. Magnetic resonance imaging showed an enhancing lesion in the inferomedial portion of the right orbit associated with opacification and enhancement of the right ethmoid, maxillary and frontal sinuses. Antineutrophil cytoplasmic antibodies (ANCA) were negative for myeloperoxidase (perinuclear ANCA) but positive for proteinase 3 (cytoplasmic ANCA). An intranasal biopsy demonstrated a nonspecific ulcer site reaction with a mixed inflammatory cell composition and focal vascular injury. Upon further questioning, the patient admitted to intranasal insufflation of cocaine confirming the diagnosis of cocaine-induced midline destructive lesions.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent updates in choroidal imaging biomarkers. 脉络膜成像生物标志物的最新进展。

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-05-13 DOI: 10.1016/j.survophthal.2025.05.005

Sumit Randhir Singh, Elham Sadeghi, Kiran Kumar Vupparaboina, Jay Chhablani

{"title":"Recent updates in choroidal imaging biomarkers.","authors":"Sumit Randhir Singh, Elham Sadeghi, Kiran Kumar Vupparaboina, Jay Chhablani","doi":"10.1016/j.survophthal.2025.05.005","DOIUrl":"10.1016/j.survophthal.2025.05.005","url":null,"abstract":"The choroid, a highly vascularized tissue, supplies the outer retina and is responsible for other functions such as thermoregulation, secretion of growth factors, and possibly emmetropization. Choroidal changes, therefore, may play a role in various chorioretinal diseases. The recent surge in publications focusing on the choroid can be attributed to improvements in both resolution and field of view of optical coherence tomography and indocyanine green angiography. Advancements in imaging have transitioned from manual to semi-automated and now fully automated methods for qualitative and quantitative choroidal analysis. These qualitative parameters include choroidal vascular patterns and focal or diffuse changes in the vascular wall, either bulbosity or tortuosity. Quantitative parameters include choroidal thickness, volume, vascularity index, contour, three-dimensional vessel quantification, and blood flow measurements using laser Doppler holography. We discuss these qualitative and quantitative biomarkers in detail, i.e., the underlying principles, clinical use, changes in normal and disease states, and their limitations. This will provide invaluable insights to clinicians in understanding the choroidal changes in physiological and pathological states.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Augmented and virtual reality in retinal care: A systematic review of their role in training, surgery, and treatment. 增强和虚拟现实在视网膜护理：系统回顾他们在培训，手术和治疗中的作用。

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-05-10 DOI: 10.1016/j.survophthal.2025.05.001

Murat Erdag, Mehmet Citirik, Ali Dal

{"title":"Augmented and virtual reality in retinal care: A systematic review of their role in training, surgery, and treatment.","authors":"Murat Erdag, Mehmet Citirik, Ali Dal","doi":"10.1016/j.survophthal.2025.05.001","DOIUrl":"10.1016/j.survophthal.2025.05.001","url":null,"abstract":"Augmented reality (AR) and virtual reality (VR) are game-changing technologies in retinal care, offering significant advancements in surgical training, diagnostic accuracy, and vision rehabilitation. We explore how AR/VR is being used in surgical training, intraoperative guidance, and vision restoration, focusing on their impact on surgical proficiency, diagnostic precision, and the management of retinal diseases. We analyzed studies from the Web of Science Core Collection, adhering to PRISMA 2020 guidelines. We included randomized controlled trials (RCTs) and prospective cohort studies that examined AR/VR applications in retinal surgery, diagnosis, and rehabilitation. Bias was evaluated using RoB 2.0 for RCTs and ROBINS-I for observational studies. Ten studies met our criteria (3 RCTs and 7 prospective cohort studies) with 6-48 participants, focusing on AR/VR's role in surgical simulation, diagnostics, and vision rehabilitation. The Eyesi Surgical Simulator significantly improved surgical skills, reduced complications, and accelerated learning curves. AR-assisted diagnostics enhanced retinal disease detection, while VR rehabilitation programs helped improve contrast sensitivity and visual acuity; however, methodological differences between studies made direct comparisons difficult. AR/VR technologies have the potential to enhance retinal care by improving surgical safety, diagnostic precision, and rehabilitation outcomes. Despite these benefits, high costs, accessibility challenges, and a lack of standardization remain significant barriers. Integrating AR/VR into medical training and clinical practice is recommended, but larger, long-term studies are needed to validate their effectiveness.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing outcomes of local and regional anesthesia in vitreoretinal surgery: A systematic review and network meta-analysis. 比较玻璃体视网膜手术中局部和区域麻醉的效果——系统综述和网络荟萃分析。

IF 5.1 2区医学

Survey of ophthalmology Pub Date : 2025-05-10 DOI: 10.1016/j.survophthal.2025.05.003

Abdulrahman Hameed Alsubhi, Saja Alanazi, Sadeem Tariq Atham, Saeed Alshahrani, Abdullah Alhumimidi, Sokinah Almusalami, Essa Alsultan, Wejdan Alghamdi, Ammr Alghamdi

{"title":"Comparing outcomes of local and regional anesthesia in vitreoretinal surgery: A systematic review and network meta-analysis.","authors":"Abdulrahman Hameed Alsubhi, Saja Alanazi, Sadeem Tariq Atham, Saeed Alshahrani, Abdullah Alhumimidi, Sokinah Almusalami, Essa Alsultan, Wejdan Alghamdi, Ammr Alghamdi","doi":"10.1016/j.survophthal.2025.05.003","DOIUrl":"10.1016/j.survophthal.2025.05.003","url":null,"abstract":"We systematically review and compare the available evidence on the various types of regional anesthesia and topical anesthesia (TA) in vitreoretinal surgery and evaluate their respective outcomes. The principles outlined in the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) extension for network meta-analysis were adhered to throughout this systematic review. The primary outcome measures were intraoperative pain score, the number of patients requiring additional anesthesia, and the number of adverse events. A preestablished protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO), ID Number: (CRD42023449755). Fifty-three studies were screened in full text, resulting in 11 with nearly 1076 patients who met our criteria. Most patients had a retrobulbar block, and the average surgical time was 48 min. Regarding the pain score, sub-Tenon (ST) injection had the best results, and TA was significantly less effective when compared to ST and peribulbar (PB) injection (SMD=1.28 and 0.88, 95 % confidence interval (CI) to 2.46 and 0.18-1.58). ST had significantly less risk of requiring additional anesthesia when compared to all other techniques. Six studies reported adverse events, and PB had the least risk of an adverse event. Future research should continue to explore direct comparisons between each type.","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0