Pediatric Obesity最新文献

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Correction to “Unintentional error in formula preparation and its simulated impact on infant weight and adiposity” 更正“配方奶粉配制中的意外错误及其对婴儿体重和肥胖的模拟影响”
IF 3.8 3区 医学
Pediatric Obesity Pub Date : 2023-08-25 DOI: 10.1111/ijpo.13074
{"title":"Correction to “Unintentional error in formula preparation and its simulated impact on infant weight and adiposity”","authors":"","doi":"10.1111/ijpo.13074","DOIUrl":"https://doi.org/10.1111/ijpo.13074","url":null,"abstract":"<p>Altazan AD, Gilmore LA, Guo J, et al. Unintentional error in formula preparation and its simulated impact on infant weight and adiposity. Pediatr Obes. 2019; 14:e12564. https://doi.org/10.1111/ijpo.12564</p><p>There was a mistake in the results section of the summary:</p><p>‘Results: Nineteen percent of bottles (20 of 636) prepared contained the recommended amount of infant formula powder.’</p><p>Should read as: ‘Nineteen percent of the bottles (121 of 636)…’.</p><p>The revised Results summary is shown below:</p><p>Nineteen percent of the bottles (121 of 636) prepared contained the recommended amount of infant formula powder. Three percent were underdispensed, and 78% of bottles were overdispensed, resulting in 11% additional infant formula powder. Mathematical modelling feeding 11% above energy requirements exclusively for 6 months for male and female infants suggested that infants at the 50th percentile for weight at birth would reach the 75th percentile with increased adiposity by 6 months.</p><p>We apologize for this error.</p>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"18 11","pages":""},"PeriodicalIF":3.8,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ijpo.13074","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41085124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Review of paediatric obesity and non-alcoholic fatty liver disease—A focus on emerging non-pharmacologic treatment strategies 儿童肥胖和非酒精性脂肪性肝病的研究综述——重点关注新兴的非药物治疗策略
IF 3.8 3区 医学
Pediatric Obesity Pub Date : 2023-08-21 DOI: 10.1111/ijpo.13067
Travis L. Piester, Nitin Jagtap, Rakesh Kalapala
{"title":"Review of paediatric obesity and non-alcoholic fatty liver disease—A focus on emerging non-pharmacologic treatment strategies","authors":"Travis L. Piester,&nbsp;Nitin Jagtap,&nbsp;Rakesh Kalapala","doi":"10.1111/ijpo.13067","DOIUrl":"https://doi.org/10.1111/ijpo.13067","url":null,"abstract":"<div>\u0000 \u0000 <p>Obesity in paediatrics has become one of the most serious public health concerns worldwide. Paediatric obesity leads to increased adult obesity and is associated with several comorbidities, both physical and psychological. Within gastroenterology, non-alcoholic fatty liver disease (NAFLD) is now the most common cause of paediatric liver disease and the most common cause of liver transplantation in young adults. Treatment for NAFLD largely focuses on treatment of obesity with weight loss strategies. Unfortunately, the traditional method of weight loss using multicomponent lifestyle modification (dietary changes, increased exercise and behavioural modification) has often led to disappointing results. In adult patients with obesity, treatment strategies have evolved to include bariatric surgery and, more recently, bariatric endoscopy. In paediatrics, the obesity and NAFLD epidemics will likely require this variety of treatment to address children in a personalized manner. Here, we present a review of paediatric obesity, paediatric NAFLD and the various treatment strategies to date. We focus on non-pharmacologic and emerging therapies, including bariatric surgery and bariatric endoscopy-based treatments. With such a large population of children and adolescents with obesity, further development of these treatments, including paediatric-focused clinical trials, is essential for these emerging modalities.</p>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"18 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"6395240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differential associations between television viewing, computer use, and adiposity by age, gender, and race/ethnicity in United States youth: A cross-sectional NHANES analysis 美国青少年年龄、性别和种族/民族对电视观看、电脑使用和肥胖的差异关联:一项横断面NHANES分析
IF 3.8 3区 医学
Pediatric Obesity Pub Date : 2023-08-14 DOI: 10.1111/ijpo.13070
Jennifer Zink, Benmei Liu, Chih-Hsiang Yang, Kirsten A. Herrick, David Berrigan
{"title":"Differential associations between television viewing, computer use, and adiposity by age, gender, and race/ethnicity in United States youth: A cross-sectional NHANES analysis","authors":"Jennifer Zink,&nbsp;Benmei Liu,&nbsp;Chih-Hsiang Yang,&nbsp;Kirsten A. Herrick,&nbsp;David Berrigan","doi":"10.1111/ijpo.13070","DOIUrl":"https://doi.org/10.1111/ijpo.13070","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Time spent on screens and adiposity change rapidly from childhood to adolescence, with differences by gender and race/ethnicity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Apply time-varying effect models (TVEMs) to a nationally representative sample of youth to identify the age ranges when the cross-sectional associations between television viewing, computer use, and adiposity are significant.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data from 8 to 15-year-olds (n = 3593) from the National Health and Nutrition Examination Survey (2011–2018) were extracted. TVEMs estimated the associations between television viewing, computer use, and fat mass index as dynamic functions of the participants' age, stratified by gender and race/ethnicity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>TVEMs revealed age-specific statistically significant associations that differed by gender and race/ethnicity. Notably, computer use was related to higher adiposity in non-Hispanic White females aged 9.3–11.4 years (slope β-range: 0.1–0.2) and in non-Hispanic Black females older than 14.8 years (β-range: 0.1–0.5). In males, these age windows were 13.5–15.0 years (non-Hispanic White, β-range: 0.1–0.2), 11.4–13.0 years (non-Hispanic Black, β-range: 0.1–0.14), and older than 13.0 years (Hispanic, β-range: 0.1–0.4).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>More research during the specific age ranges in the demographic subgroups identified here could increase our understanding of tailored interventions in youth.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"18 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2023-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"6345108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effects of obesity on longitudinal ventricular and atrial strain in a rural population of Spanish children and adolescents, evaluated by a new strain software 肥胖对西班牙农村儿童和青少年纵向心室和心房应变的影响,通过一种新的应变软件进行评估
IF 3.8 3区 医学
Pediatric Obesity Pub Date : 2023-08-09 DOI: 10.1111/ijpo.13069
Cristhian H. Aristizábal-Duque, Juan Fernández Cabeza, Isabel María Blancas Sánchez, Mónica Delgado Ortega, Pilar Aparicio-Martinez, Manuel Romero Salda?a, Francisco Javier Fonseca del Pozo, Manuel Pan álvarez-Ossorio, Martín Ruíz Ortiz, María Dolores Mesa Rubio
{"title":"The effects of obesity on longitudinal ventricular and atrial strain in a rural population of Spanish children and adolescents, evaluated by a new strain software","authors":"Cristhian H. Aristizábal-Duque,&nbsp;Juan Fernández Cabeza,&nbsp;Isabel María Blancas Sánchez,&nbsp;Mónica Delgado Ortega,&nbsp;Pilar Aparicio-Martinez,&nbsp;Manuel Romero Salda?a,&nbsp;Francisco Javier Fonseca del Pozo,&nbsp;Manuel Pan álvarez-Ossorio,&nbsp;Martín Ruíz Ortiz,&nbsp;María Dolores Mesa Rubio","doi":"10.1111/ijpo.13069","DOIUrl":"https://doi.org/10.1111/ijpo.13069","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Objectives</h3>\u0000 \u0000 <p>Research on the relationship between body mass index (BMI) and strain values in children and adolescents is limited. Our aim was to analyse the relationship between BMI and strain values of both ventricles and left atrium in children and adolescents.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Both ventricles and left atrial strain values were compared among different BMI categories in children and adolescents from a town in the South of Spain.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 198 subjects, aged 6–17 years, 53% were of normal weight, 26% were overweight and 21% had obesity. Lower absolute values of left ventricular global longitudinal strain (25.9 ± 2.0% vs. 26.9 ± 2.2%, <i>p</i> = 0.002) and right ventricular free wall longitudinal strain (29.5 ± 4.2% vs. 30.8 ± 4.5%, <i>p</i> = 0.04) were found in subjects with obesity and overweight versus subjects with normal weight. A lower right ventricular four-chamber longitudinal strain was also observed in males with obesity and overweight (24.8 ± 3.3% vs. 26.4 ± 3.6%, <i>p</i> = 0.03). Statistically significant negative correlations of BMI were found for all ventricular, but not atrial, strain values in univariate analysis. This association turned non-significant for right ventricular four-chamber longitudinal strain in multivariate analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Utilizing this new strain software, children and adolescents with high BMI were associated with significantly lower values for left and right ventricular free wall longitudinal strain, without impact in left atrial strain.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"18 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"6310360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal associations between diet quality, sedentary behaviours and physical activity and risk of overweight and obesity in preschool children: The ToyBox-study 学龄前儿童饮食质量、久坐行为和身体活动与超重和肥胖风险之间的纵向关联:toybox研究
IF 3.8 3区 医学
Pediatric Obesity Pub Date : 2023-07-31 DOI: 10.1111/ijpo.13068
María L. Miguel-Berges, Theodora Mouratidou, Alba Santaliestra-Pasias, Odysseas Androutsos, Violeta Iotova, Sonya Galcheva, Marieke De Craemer, Greet Cardon, Berthold Koletzko, Zbigniew Kulaga, Yannis Manios, Luis A. Moreno, the ToyBox-study group
{"title":"Longitudinal associations between diet quality, sedentary behaviours and physical activity and risk of overweight and obesity in preschool children: The ToyBox-study","authors":"María L. Miguel-Berges,&nbsp;Theodora Mouratidou,&nbsp;Alba Santaliestra-Pasias,&nbsp;Odysseas Androutsos,&nbsp;Violeta Iotova,&nbsp;Sonya Galcheva,&nbsp;Marieke De Craemer,&nbsp;Greet Cardon,&nbsp;Berthold Koletzko,&nbsp;Zbigniew Kulaga,&nbsp;Yannis Manios,&nbsp;Luis A. Moreno,&nbsp;the ToyBox-study group","doi":"10.1111/ijpo.13068","DOIUrl":"https://doi.org/10.1111/ijpo.13068","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Lifestyle behaviours related to diet and physical activity are associated with increased risk of obesity and evidence suggests that associations might be stronger when a synergetic effect is examined.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To examine the cross-sectional and longitudinal associations between diet, screen time (ST) and step recommendations and risk of overweight and obesity in European preschoolers participating in the ToyBox-study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this cluster-randomized clinical trial, 718 children (51.4% boys) from six European countries participated. Parents filled out questionnaires with information on socio-demographic status, step recommendations and ST.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Longitudinal results indicate that participants having a low Diet Quality Index (DQI), not meeting ST and step recommendations at T0 and T1 had higher odds of having overweight/obesity at T1 (odds ratio [OR] = 1.116; 95% confidence interval [CI] = 1.104–2.562) than those children having a high DQI and meeting ST and step recommendations at T0 and T1. Similarly, participants having a high DQI, but not meeting ST and step recommendations at T0 and T1 had increased odds of having overweight/obesity (OR = 2.515; 95% CI = 1.171–3.021).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The proportion of participants having a low DQI, not adhering to both step and ST recommendations was very high, and it was associated with a higher probability of having overweight and obesity.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"18 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ijpo.13068","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"6465215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electronic phenotypes to distinguish clinician attention to high body mass index, hypertension, lipid disorders, fatty liver and diabetes in pediatric primary care: Diagnostic accuracy of electronic phenotypes compared to masked comprehensive chart review 电子表型在儿科初级保健中区分临床医生对高体重指数、高血压、脂质紊乱、脂肪肝和糖尿病的关注:电子表型与蒙面综合图表比较的诊断准确性
IF 3.8 3区 医学
Pediatric Obesity Pub Date : 2023-07-17 DOI: 10.1111/ijpo.13066
Christy B. Turer, Jenny J. Park, Olga T. Gupta, Charina Ramirez, Mujeeb A. Basit, Daniel F. Heitjan, Sarah E. Barlow
{"title":"Electronic phenotypes to distinguish clinician attention to high body mass index, hypertension, lipid disorders, fatty liver and diabetes in pediatric primary care: Diagnostic accuracy of electronic phenotypes compared to masked comprehensive chart review","authors":"Christy B. Turer,&nbsp;Jenny J. Park,&nbsp;Olga T. Gupta,&nbsp;Charina Ramirez,&nbsp;Mujeeb A. Basit,&nbsp;Daniel F. Heitjan,&nbsp;Sarah E. Barlow","doi":"10.1111/ijpo.13066","DOIUrl":"https://doi.org/10.1111/ijpo.13066","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background/Objectives</h3>\u0000 \u0000 <p>Electronic phenotyping is a method of using electronic-health-record (EHR) data to automate identifying a patient/population with a characteristic of interest. This study determines validity of using EHR data of children with overweight/obesity to electronically phenotype evidence of clinician ‘attention’ to high body mass index (BMI) and each of four distinct comorbidities.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We built five electronic phenotypes classifying 2-18-year-old children with overweight/obesity (n = 17,397) by electronic/health-record evidence of distinct attention to high body mass index, hypertension, lipid disorders, fatty liver, and prediabetes/diabetes. We reviewed, selected and cross-checked random charts to define items clinicians select in EHRs to build problem lists, and to order medications, laboratory tests and referrals to electronically classify attention to overweight/obesity and each comorbidity. Operating characteristics of each clinician-attention phenotype were determined by comparing comprehensive chart review by reviewers masked to electronic classification who adjudicated evidence of clinician attention to high BMI and each comorbidity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In a random sample of 817 visit-records reviewed/coded, specificity of each electronic phenotype is 99%–100% (with PPVs ranging from 96.8% for prediabetes/diabetes to 100% for dyslipidemia and hypertension). Sensitivities of the attention classifications range from 69% for hypertension (NPV, 98.9%) to 84.7% for high-BMI attention (NPV, 92.3%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Electronic phenotypes for clinician attention to overweight/obesity and distinct comorbidities are highly specific, with moderate (BMI) to modest (each comorbidity) sensitivity. The high specificity supports using phenotypes to identify children with prior high-BMI/comorbidity attention.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"18 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"6366859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in insulin resistance, body mass index and degree of obesity among junior high school students: A comparison before and after the outbreak of the COVID-19 pandemic 新冠肺炎疫情前后初中生胰岛素抵抗、体重指数和肥胖程度的变化
IF 3.8 3区 医学
Pediatric Obesity Pub Date : 2023-07-06 DOI: 10.1111/ijpo.13065
Yuka Suganuma, Hiroshi Takahashi, Hironari Sano, Yuusaku Hayashi, Rimei Nishimura
{"title":"Changes in insulin resistance, body mass index and degree of obesity among junior high school students: A comparison before and after the outbreak of the COVID-19 pandemic","authors":"Yuka Suganuma,&nbsp;Hiroshi Takahashi,&nbsp;Hironari Sano,&nbsp;Yuusaku Hayashi,&nbsp;Rimei Nishimura","doi":"10.1111/ijpo.13065","DOIUrl":"https://doi.org/10.1111/ijpo.13065","url":null,"abstract":"<div>\u0000 \u0000 <p>This study aimed to investigate how the COVID-19 pandemic since 2020 has affected the homeostasis model assessment of insulin resistance (HOMA-IR), body mass index (BMI) and degree of obesity among Japanese children. HOMA-IR, BMI and degree of obesity were calculated for 378 children 14–15 years old (boys/girls, 208/170) who underwent checkups during 2015–2021. Changes in these parameters over time and correlations between parameters were assessed, and the proportions of participants with IR (HOMA-IR ≥2.5) were compared. HOMA-IR values increased significantly over the study period (<i>p</i> &lt; 0.001), with a significantly large proportion of participants with IR in 2020–2021 (<i>p</i> &lt; 0.001). Conversely, BMI and degree of obesity did not change significantly. HOMA-IR did not correlate with BMI or degree of obesity during 2020–2021. In conclusion, the COVID-19 pandemic may have had an impact on the increase in the proportion of children with IR, regardless of BMI or degree of obesity.</p>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"18 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"6292569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperglycemia: A determinant of cardiac autonomic dysfunction in youth with obesity across the spectrum of glycemic regulation 高血糖:一个决定因素心脏自主神经功能障碍的青年肥胖与血糖调节的频谱
IF 3.8 3区 医学
Pediatric Obesity Pub Date : 2023-06-13 DOI: 10.1111/ijpo.13063
Heba El-Ayash, Maurice Puyau, Fida Bacha
{"title":"Hyperglycemia: A determinant of cardiac autonomic dysfunction in youth with obesity across the spectrum of glycemic regulation","authors":"Heba El-Ayash,&nbsp;Maurice Puyau,&nbsp;Fida Bacha","doi":"10.1111/ijpo.13063","DOIUrl":"https://doi.org/10.1111/ijpo.13063","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To characterize the determinants of heart rate variability (HRV) in youth with obesity across the glycemia spectrum.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 94 adolescents, 15 ± 2.1 years (21 with normal weight, 23 with overweight-normal glucose tolerance, 26 with prediabetes and 24 with type 2 diabetes [T2D]) underwent an assessment of body composition (dual-energy x-ray absorptiometry), 2-h oral glucose tolerance test with the calculation of indices of glycemia and insulin sensitivity (IS), inflammatory markers (high-sensitivity C-reactive protein [hs-CRP] and tumour necrosis factor-α [TNF-α]), and HRV by peripheral arterial tonometry.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The HRV frequency-domain index (low-frequency to high-frequency ratio [LF/HF]), an estimate of the ratio between sympathetic and parasympathetic activity, increased across the glycemic spectrum, and was highest in T2D compared with the other three groups (<i>p</i> = 0.004). LF/HF correlated with %body fat (<i>r</i> = 0.22, <i>p</i> = 0.04); fasting (<i>r</i> = 0.39, <i>p</i> &lt; 0.001), 2-h (<i>r</i> = 0.31, <i>p</i> = 0.004), and area under the curve glucose (<i>r</i> = 0.32, <i>p</i> = 0.003); hs-CRP (<i>r</i> = 0.33, <i>p</i> = 0.002) and TNF-α (<i>r</i> = 0.38, <i>p</i> = 0.006). In a linear regression model, fasting glucose (<i>β</i> = 0.39, <i>p</i> = 0.003) and hs-CRP (<i>β</i> = 0.21, <i>p</i> = 0.09) contributed to the variance in Ln LF/HF independent of IS, %body fat, age, sex, race-ethnicity and Tanner stage (<i>R</i><sup>2</sup> = 0.23, <i>p</i> = 0.013).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Youth with impaired glucose regulation have evidence of cardiac autonomic dysfunction with decreased HRV, and sympathetic overdrive (increased LF/HF). This dysfunction is mainly related to glycemia and systemic inflammation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"18 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"6341557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infant effortful control predicts BMI trajectories from infancy to adolescence 婴儿努力控制预示着从婴儿期到青春期的BMI轨迹
IF 3.8 3区 医学
Pediatric Obesity Pub Date : 2023-06-08 DOI: 10.1111/ijpo.13059
LillyBelle K. Deer, Jenalee R. Doom, Kylie K. Harrall, Deborah H. Glueck, Laura M. Glynn, Curt A. Sandman, Elysia Poggi Davis
{"title":"Infant effortful control predicts BMI trajectories from infancy to adolescence","authors":"LillyBelle K. Deer,&nbsp;Jenalee R. Doom,&nbsp;Kylie K. Harrall,&nbsp;Deborah H. Glueck,&nbsp;Laura M. Glynn,&nbsp;Curt A. Sandman,&nbsp;Elysia Poggi Davis","doi":"10.1111/ijpo.13059","DOIUrl":"https://doi.org/10.1111/ijpo.13059","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Effortful control, or the regulation of thoughts and behaviour, is a potential target for preventing childhood obesity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To assess effortful control in infancy through late childhood as a predictor of repeated measures of body mass index (BMI) from infancy through adolescence, and to examine whether sex moderates the associations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Maternal report of offspring effortful control and measurements of child BMI were obtained at 7 and 8 time points respectively from 191 gestational parent/child dyads from infancy through adolescence. General linear mixed models were used.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Effortful control at 6 months predicted BMI trajectories from infancy through adolescence, <i>F</i>(5,338) = 2.75, <i>p</i> = 0.03. Further, when effortful control at other timepoints were included in the model, they added no additional explanatory value. Sex moderated the association between 6-month effortful control and BMI, <i>F</i>(4, 338) = 2.59, <i>p</i> = 0.03, with poorer infant effortful control predicting higher BMI in early childhood for girls, and more rapid increases in BMI in early adolescence for boys.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Effortful control in infancy was associated with BMI over time. Specifically, poor effortful control during infancy was associated with higher BMI in childhood and adolescence. These findings support the argument that infancy may be a sensitive window for the development of later obesity.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"18 9","pages":""},"PeriodicalIF":3.8,"publicationDate":"2023-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"6153390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationships examined: Parent and child readiness to change and sociodemographic characteristics in family based weight loss treatment 关系检验:父母和孩子准备改变和社会人口特征的家庭为基础的减肥治疗
IF 3.8 3区 医学
Pediatric Obesity Pub Date : 2023-06-06 DOI: 10.1111/ijpo.13062
Melissa Ramel, Denise E. Wilfley, Rachel Tabak, Daphne Lew, Nasreen A. Moursi, Colleen Kilanowski, Steven R. Cook, Ihouma U. Eneli, Teresa Quattrin, Kenneth B. Schechtman, Leonard H. Epstein
{"title":"Relationships examined: Parent and child readiness to change and sociodemographic characteristics in family based weight loss treatment","authors":"Melissa Ramel,&nbsp;Denise E. Wilfley,&nbsp;Rachel Tabak,&nbsp;Daphne Lew,&nbsp;Nasreen A. Moursi,&nbsp;Colleen Kilanowski,&nbsp;Steven R. Cook,&nbsp;Ihouma U. Eneli,&nbsp;Teresa Quattrin,&nbsp;Kenneth B. Schechtman,&nbsp;Leonard H. Epstein","doi":"10.1111/ijpo.13062","DOIUrl":"https://doi.org/10.1111/ijpo.13062","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Family based treatment is an effective, multipronged approach to address obesity as it plagues families.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To investigate the relationships among sociodemographic characteristics (e.g., education and income), body mass index (BMI) and race/ethnicity with readiness to change for parents enrolled in the Primary care pediatrics, Learning, Activity and Nutrition (PLAN) study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Multivariate linear regressions tested two hypotheses: (1) White parents will have higher levels of baseline readiness to change, when compared to Black parents; (2) parents with higher income and education will have higher levels of readiness to change at baseline.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A positive relationship exists between baseline parent BMI and readiness to change (Pearson correlation, 0.09, <i>p</i> &lt; 0.05); statistically significant relationships exist between parent education level (−0.14, <i>p</i> &lt; 0.05), income (0.04, <i>p</i> &lt; 0.05) and readiness to change. Additionally, a statistically significant relationship exists, with both White (β, −0.10, <i>p</i> &lt; 0.05), and Other, non-Hispanic (−0.10, <i>p</i> &lt; 0.05) parents exhibiting lower readiness to change than Black, non-Hispanic parents. Child data did not indicate significant relationships between race/ethnicity and readiness to change.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Results demonstrate that investigators should consider sociodemographic characteristic factors and different levels of readiness to change in participants enrolling in obesity interventions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"18 9","pages":""},"PeriodicalIF":3.8,"publicationDate":"2023-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"6104484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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