患有自闭症谱系障碍的儿童和青少年的体重状况：加拿大安大略省初级保健电子医疗记录和相关卫生管理数据集的横断面分析

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Obesity Pub Date : 2025-03-18 DOI:10.1111/ijpo.70000

Laura M. Kinlin, Natasha R. Saunders, Sarah Carsley, Charles Keown-Stoneman, Karen Tu, Lonnie Zwaigenbaum, Catherine S. Birken

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引用次数: 0

摘要

背景：患有自闭症谱系障碍（ASD）的个体肥胖和体重不足的风险可能会增加。目的：探讨儿童和青少年ASD与体重状况之间的关系，并对个体和社区水平的社会人口因素进行调整。方法：我们使用来自加拿大安大略省的卫生管理和人口统计数据，对≥2岁和≤18岁的儿童和青少年进行了横断面研究。使用2011年至2016年大型初级保健数据库中的增长测量数据，我们使用世界卫生组织的定义对体重状况进行了分类。我们根据先前验证的算法定义了ASD。结果：我们纳入了568名ASD儿童和青少年，32967名非ASD儿童和青少年。与非ASD患者相比，体重不足的患病率为3.5%对1.9%，超重的患病率为19.0%对18.2%，肥胖的患病率为12.9%对7.3%，严重肥胖的患病率为5.8%对2.2%。在完全校正多项logistic回归模型中，ASD仍与体重不足相关(校正优势比[aOR] 2.02；95%可信区间[CI] 1.27-3.20)、肥胖(aOR 1.87；95% CI 1.44-2.43)和重度肥胖(aOR 2.62；95% ci 1.81-3.80)。结论：患有ASD的儿童和青少年体重不足、肥胖和严重肥胖的风险增加，与社会人口学特征无关。在这一人群中，应对生长和体重状况的策略是必要的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Weight status of children and adolescents with autism spectrum disorder: A cross-sectional analysis of primary care electronic medical records and linked health administrative datasets in Ontario, Canada

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Background

Individuals with autism spectrum disorder (ASD) may be at increased risk of both obesity and underweight.

Objective

To examine the association between ASD and weight status in children and adolescents, adjusting for individual- and neighbourhood-level sociodemographic factors.

Methods

We conducted a cross-sectional study of children and adolescents ≥2 and ≤18 years old using health administrative and demographic data from Ontario, Canada. Using growth measurements from a large primary care database between 2011 and 2016, we categorized weight status using World Health Organization definitions. We defined ASD based on a previously validated algorithm.

Results

We included 568 children and adolescents with ASD and 32 967 without ASD. Comparing those with ASD to those without ASD, prevalence of underweight was 3.5% versus 1.9%, overweight 19.0% versus 18.2%, obesity 12.9% versus 7.3%, and severe obesity 5.8% versus 2.2%. In the fully adjusted multinomial logistic regression model, ASD remained associated with underweight (adjusted odds ratio [aOR] 2.02; 95% confidence interval [CI] 1.27–3.20), obesity (aOR 1.87; 95% CI 1.44–2.43) and severe obesity (aOR 2.62; 95% CI 1.81–3.80).

Conclusion

Children and adolescents with ASD are at increased risk of underweight, obesity, and severe obesity, independent of sociodemographic characteristics. Strategies addressing growth and weight status are warranted in this population.

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来源期刊

Pediatric Obesity PEDIATRICS-

CiteScore

7.30

自引率

5.30%

发文量

117

审稿时长

6-12 weeks

期刊介绍： Pediatric Obesity is a peer-reviewed, monthly journal devoted to research into obesity during childhood and adolescence. The topic is currently at the centre of intense interest in the scientific community, and is of increasing concern to health policy-makers and the public at large. Pediatric Obesity has established itself as the leading journal for high quality papers in this field, including, but not limited to, the following: Genetic, molecular, biochemical and physiological aspects of obesity – basic, applied and clinical studies relating to mechanisms of the development of obesity throughout the life course and the consequent effects of obesity on health outcomes Metabolic consequences of child and adolescent obesity Epidemiological and population-based studies of child and adolescent overweight and obesity Measurement and diagnostic issues in assessing child and adolescent adiposity, physical activity and nutrition Clinical management of children and adolescents with obesity including studies of treatment and prevention Co-morbidities linked to child and adolescent obesity – mechanisms, assessment, and treatment Life-cycle factors eg familial, intrauterine and developmental aspects of child and adolescent obesity Nutrition security and the "double burden" of obesity and malnutrition Health promotion strategies around the issues of obesity, nutrition and physical activity in children and adolescents Community and public health measures to prevent overweight and obesity in children and adolescents.