Pediatric Obesity最新文献

{"title":"Effectiveness of a Socioecological School-Based 24-h Movement Behaviour Intervention on Lifestyle Behaviours Among Children and Adolescents With Overweight or Obesity: A Gender-Stratified Quasi-Experimental Study","authors":"Moazzam Tanveer,&nbsp;Cai Yujun,&nbsp;Georgian Badicu,&nbsp;Junaid Sarfraz Khan,&nbsp;Alexios Batrakoulis,&nbsp;Ejaz Asghar,&nbsp;António Raposo,&nbsp;Umar Tanveer,&nbsp;Nadeem Roy,&nbsp;Luca Paolo Ardigò","doi":"10.1111/ijpo.70160","DOIUrl":"https://doi.org/10.1111/ijpo.70160","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Childhood obesity and inadequate physical activity are major public health concerns in Pakistan. Evidence on multicomponent school-based interventions targeting 24-h movement behaviours, particularly with gender-specific approaches, remains limited.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A 12-week quasi-experimental cluster-controlled study was conducted in eight public schools in Lahore, Pakistan. A total of 1200 children and adolescents (577 boys, 623 girls; aged 9–17 years) were assigned to an intervention group (<i>n</i> = 570) or a control group (<i>n</i> = 630). The intervention, guided by the socioecological model, included enhanced physical education, extracurricular physical activity, health education, parental engagement and supportive school environments. Outcomes included anthropometric measures and 24-h movement behaviours. Intervention effects were analysed using repeated-measures analysis of variance (ANOVA) and general linear mixed models (<i>p</i> &lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Significant group-by-time interactions were observed for physical activity (<i>η</i>² = 0.28), screen time (<i>η</i>² = 0.15), sleep duration (<i>η</i>² = 0.16) and fast-food consumption (<i>η</i>² = 0.07) (all <i>p</i> &lt; 0.001). The prevalence of <i>overweight and obesity among children and adolescents</i> declined from 31.0% to 28.0% in the intervention group but increased from 36.0% to 38.0% in the control group (<i>p</i> = 0.005). Physical activity guideline adherence increased from 26.3% to 71.8% among boys and from 22.2% to 63.3% among girls (both <i>p</i> &lt; 0.001). Significant reductions in BMI, waist circumference and waist-to-height ratio were also observed in the intervention group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>A multicomponent, socioecological, school-based intervention effectively improved movement behaviours, dietary habits, parental support and outcomes related to overweight and obesity among Pakistani children and adolescents. These findings support integrated school- and family-based strategies for preventing childhood obesity across both boys and girls.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"21 11","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149311387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to ‘Latent Class Analysis of Prenatal Characteristics and Their Associations With Early Childhood Weight’","authors":"","doi":"10.1111/ijpo.70162","DOIUrl":"https://doi.org/10.1111/ijpo.70162","url":null,"abstract":"<p>\u0000 <span>C. N. Kim</span>, <span>M. J. Messito</span>, <span>C. Duh-Leong</span>, et al., “ <span>Latent Class Analysis of Prenatal Characteristics and Their Associations With Early Childhood Weight</span>,” <i>Pediatric Obesity</i> <span>21</span>, no. <span>10</span> (<span>2026</span>): e70151, https://doi.org/10.1111/ijpo.70151.\u0000 </p><p>In the Funding section of the originally published article, three National Institutes of Health (NIH) career development awards were incorrectly included: K23HD081077 (NICHD; PI: Gross), K23ES035461 (NIEHS; PI: Duh-Leong), and K23HL159326 (NHLBI; PI: Katzow). These awards did not directly support the research and should not have been included in the funding acknowledgment.</p><p>The correct funding acknowledgement should read:</p><p>‘This research was supported by the United States Department of Agriculture (USDA) Agriculture and Food Research Initiative (AFRI) grants 2011-68001-30207 and 2017-68001-26350, and the Health Resources and Services Administration (HRSA) training grant T32HP22238 (Kim)’.</p><p>We apologize for this error.</p>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"21 11","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ijpo.70162","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149310849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pilot Implementation of an Adapted Online Clinic-Community Model for Childhood Obesity","authors":"Chu Shan Elaine Chew,&nbsp;Khairunisa Binte Khaider,&nbsp;Cody D. Neshteruk,&nbsp;Sarah C. Armstrong","doi":"10.1111/ijpo.70161","DOIUrl":"https://doi.org/10.1111/ijpo.70161","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Intensive health-behaviour lifestyle treatment is recommended for paediatric obesity, but evidence for young children and synchronous online delivery remains limited.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate the feasibility, acceptability, and preliminary effectiveness of an adapted online clinic-community model for children aged 4 to &lt; 8 years with overweight or obesity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this two-arm randomized controlled trial, children were randomized to an online family-based intervention or usual care. The primary outcome was treatment dose at 6 months, defined as intervention contact hours. Secondary outcomes included BMI z-score, percentage of the 95th BMI percentile, health-related quality of life, eating behaviours, and perceived movement skills at 3 and 6 months.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Forty children were enrolled; mean age was 6.6 ± 1.0 years and 58% were male. At 6 months, 70% of intervention participants achieved at least 26 treatment hours. Although the between-group differences were not statistically significant, the intervention group demonstrated numerically greater reductions in BMI z-score (−0.2 ± 0.3 vs. −0.1 ± 0.1; <i>p</i> = 0.091) and percentage of the 95th BMI percentile (−3.5 ± 6.4 vs. −0.2 ± 4.0; <i>p</i> = 0.075). Physical quality of life improved at 3 and 6 months, object control skills at 3 months, and perceived locomotor skills at 6 months.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The adapted online model was feasible and acceptable, with preliminary improvements in physical quality of life, movement skills, and BMI metrics. Larger adequately powered trials are needed to confirm effectiveness and longer-term outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"21 11","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149311388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Who Benefited Most? Identifying Parent–Child Dyads With Improved Weight Outcomes in the Feel4Diabetes Study","authors":"Dimitra-Irinna Vitoratou,&nbsp;Eva Karaglani,&nbsp;Matzourana Argyropoulou,&nbsp;Konstantina Dimakopoulou,&nbsp;Violeta Iotova,&nbsp;Yuliya Bazdarska,&nbsp;Tsvetalina Tankova,&nbsp;Greet Cardon,&nbsp;Luis A. Moreno,&nbsp;Imre Rurik,&nbsp;Péter Torzsa,&nbsp;Jaana Lindström,&nbsp;Konstantinos Makrilakis,&nbsp;Yannis Manios","doi":"10.1111/ijpo.70159","DOIUrl":"10.1111/ijpo.70159","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Family-based interventions offer a promising solution to the pressing global health concern of childhood obesity by addressing the interconnected behaviours of parents and children. Nevertheless, limited evidence identifies which families benefit most when outcomes are evaluated at the parent–child dyad level.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To identify which parent–child dyads experienced clinically meaningful improvements in weight status over 1- and 2-year periods within the Feel4Diabetes study, a school- and community-based intervention targeting European families at risk for Type 2 diabetes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data were drawn from 2402 high-risk families across six European countries. For participants with overweight/obesity, improvement meant ≥ 5% parental weight loss and a ≥ 0.15-unit child BMI-<i>z</i> reduction. Multiple logistic regression models identified socio-demographic and contextual predictors of dyadic improvement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>After 2 years, 5.3% of families achieved improvements in both parent and child. Significant predictors of dyadic success included intervention group participation [OR = 2.56 (95% CI: 1.31–5.03)] and residing in high-income countries under austerity measures [OR = 2.44 (1.00–6.02)]. Girls were more likely to improve than boys, while full-time maternal employment was associated with lower odds of dyadic improvement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Sustained benefits were observed in a subset of families, highlighting the need for tailored, context-sensitive family-centred obesity prevention strategies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"21 10","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13633390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149101689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Composite Summary Scores Capture Obesogenic Eating Risk Among Preadolescents Using the Child Eating Behaviour Questionnaire","authors":"Timothy J. Renier,&nbsp;Delaina D. Carlson,&nbsp;Diane Gilbert-Diamond,&nbsp;Jennifer A. Emond","doi":"10.1111/ijpo.70146","DOIUrl":"https://doi.org/10.1111/ijpo.70146","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The Child Eating Behaviour Questionnaire (CEBQ) measures multiple appetitive traits. We used a data-driven approach to identify simplified composite scores across traits to summarise obesogenic eating risk.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>From 354 unrelated 9-to-12-year-olds, we examined 29 items from CEBQ domains measuring food approach or avoidance: food responsiveness, enjoyment of food, emotional over-eating, desire to drink, satiety responsiveness, slowness in eating, and emotional under-eating. Factor analysis assuming a single factor was used to reduce the number of items in one composite, obesogenic eating score. Candidate composite scores averaged items with standardized loadings ≥|0.40|, ≥|0.50|, or ≥|0.70|. Those scores, the individual domain scores, and a theory-driven composite score were correlated with BMI z-scores and two obesity polygenic risk scores (PRS, subset <i>n</i> = 247).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The three data-driven composite scores (4–18 items) and the theory driven score were highly correlated with each other (<i>r</i> range: 0.77–0.97) and more strongly correlated with BMI (<i>r</i> range: 0.38–0.42; FDR <i>q</i> &lt; 0.001) than any individual domain score. Similarly, these scores were significantly correlated with both PRSs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>We identified CEBQ composite scores related to child BMI and genetic obesity risk, suggesting a subset of CEBQ items can measure obesity risk conferred by child appetitive traits.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"21 10","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ijpo.70146","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149068606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Latent Class Analysis of Prenatal Characteristics and Their Associations With Early Childhood Weight","authors":"Christina N. Kim,&nbsp;Mary Jo Messito,&nbsp;Carol Duh-Leong,&nbsp;Michelle Katzow,&nbsp;Noelle Armstrong,&nbsp;Kathleen Woolf,&nbsp;Rachel S. Gross","doi":"10.1111/ijpo.70151","DOIUrl":"https://doi.org/10.1111/ijpo.70151","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Identify patterns of obesity-related prenatal characteristics across ecological system levels and examine associations with child weight at 2 years old.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Secondary analyses were conducted using data from 533 low-income Hispanic families enrolled in a childhood obesity prevention intervention. Prenatal characteristics were assessed during the 3rd trimester and child weights at 2 years. Latent class analysis was conducted to identify groups of pregnant individuals with different patterns of prenatal characteristics. Associations between class membership and child weight outcomes at age 2 years were examined using the manual Bolck–Croon–Hagenaars method, controlling for intervention status.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Three groups were identified: <i>Non-US born/Lower adverse SDOH</i> (51%), <i>Non-US born/Higher adverse SDOH</i> (25%) and <i>US born/Lower adverse SDOH</i> (24%). Children of participants in the <i>Non-US born/Higher adverse SDOH</i> had significantly higher weight-for-age <i>z</i>-scores and higher odds of overweight or obesity compared to children of participants in the <i>Non-US born/Lower adverse SDOH</i> (<i>M</i>_diff = 0.61, SE = 0.21, <i>p</i> = 0.003, 95% CI [0.27, 0.95]; aOR = 2.83, 95% CI [1.09, 2.59]) and <i>Non-US born/Higher adverse SDOH burden</i> (<i>M</i>_diff = 0.55, SE = 0.20, <i>p</i> = 0.006, 95% CI [0.22, 0.89]; aOR = 2.83, 95% CI [1.09, 2.59]).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Higher concurrent levels of psychosocial stressors and material hardships during pregnancy may pose a particular risk for excess weight in early childhood, especially for children of non-US-born pregnant individuals.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"21 10","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149068444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Teleintervention Maintenance Programs for Children (Age 6–12) and Adolescents (Age 13–18) With Overweight or Obesity—Promoting a Healthy Lifestyle: A Systematic Review","authors":"Anna Wittmann,&nbsp;Pia Späth,&nbsp;Feline Zocher,&nbsp;Eckard Nagel,&nbsp;Michael Lauerer,&nbsp;Magdalena Schellenberg","doi":"10.1111/ijpo.70158","DOIUrl":"https://doi.org/10.1111/ijpo.70158","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Weight management and maintenance of healthy habits are crucial in combating paediatric obesity. This systematic review examines outcomes beyond BMI in teleintervention maintenance programmes, with a focus on sustaining a healthy lifestyle.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A PubMed, LIVIVO and Web of Science search was conducted for publications between 2012 and 4 November 2025 to identify primary studies evaluating teleintervention maintenance programmes of at least 12 weeks' duration, delivered to children and adolescents with overweight or obesity following structured obesity treatment. We extracted healthy lifestyle parameters (e.g., quality of life), behaviour change (e.g., diet) and clinician-reported outcomes (e.g., BMI). Quality assessment was tailored to study type. As data did not permit meta-analysis, we performed a narrative synthesis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Screening 2543 articles yielded 6 RCTs and 2 pre-post studies. Findings highlight improvements in psychosocial outcomes (e.g., social well-being), lifestyle modifications in daily choices (e.g., dietary patterns) and behaviours (e.g., screen time), and statistically significant outcomes including reductions in body fat percentage, metabolic profile improvements, cardiovascular enhancements and BMI stabilisation. Feasibility insights were also gained.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Teleintervention maintenance programmes following structured paediatric obesity treatment were associated with stabilisation of previously achieved weight-related and behavioural gains, rather than greater weight loss than comparator care, alongside consistently high feasibility and substantial reductions in healthcare visits and cost. Given the heterogeneity of designs and outcomes, findings should be interpreted as directional rather than pooled effect estimates, and a human component may be necessary to sustain them.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"21 10","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ijpo.70158","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149068443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obesity Disparities in California Vary by School Ethnic Segregation and School Neighbourhood Income","authors":"Sydney Miller,&nbsp;Emma Sanchez-Vaznaugh,&nbsp;Brisa N. Sánchez","doi":"10.1111/ijpo.70157","DOIUrl":"https://doi.org/10.1111/ijpo.70157","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study examines how ethnic disparities in childhood obesity differ across combinations of school ethnic composition and school neighbourhood income in California, to identify the contexts in which disparities are greatest. Prior studies have been unable to study this due to the high correlation between segregation and income.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This observational study focuses on overweight/obesity data objectively measured among California public school children in 2018/2019 and school neighbourhood data from the American Community Survey, using a ‘within versus between’ differences analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Black and Latino children had higher overweight/obesity prevalence than White children, but disparities varied across schools. Disparities were smallest in integrated low-income schools: the Black versus White (B/W) and the Latino versus White (L/W) disparities were 3% and 10%, respectively. In integrated high-income schools, these disparities were 8% and 13%, respectively. Disparities between segregated low-income schools and segregated high-income schools were 11% (B/W) and 14% (L/W), and 22% (B/W) and 26% (L/W). The largest disparity was between minority children in minority-segregated low-income schools compared to White children in White-segregated high-income schools (B/W disparity 23% and L/W 28%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Place-based interventions to reduce childhood obesity should prioritize low-income, ethnically segregated schools, where the largest disparities were observed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"21 10","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ijpo.70157","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149068442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adherence to the Mediterranean Diet Is Associated With a Lower Risk of Obesity in Children Under 18 Years: A Comprehensive Systematic Review and Meta-Analysis","authors":"Maryam Gholami Shahrbabak,&nbsp;Azam Gholami Shahrbabak,&nbsp;Artin Ebrahimi Meymand,&nbsp;Karen Tahmasebi Abdar,&nbsp;Maryam Mobasheri-Shiri","doi":"10.1111/ijpo.70154","DOIUrl":"https://doi.org/10.1111/ijpo.70154","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The Mediterranean Diet (MedDiet) is a plant-rich dietary pattern associated with favourable adiposity profiles, making it a relevant model for studying obesity risk in children and adolescents. This study aims to investigate the association between adherence to the MedDiet and risk of obesity in children and adolescents.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>An extensive search in databases PubMed/Medline, Scopus, Web of Science Core Collection, the Cochrane Library and Google Scholar up to October 2025 was conducted. Cohort studies which reported means and standard deviations for the body mass index (BMI) levels and MedDiet adherence scores, and crude and adjusted odds ratios (OR) for overweight or obesity among the children with high and low adherence to the MedDiet were eligible for inclusion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty three articles (26 studies) met the inclusion criteria. Results demonstrated that the mean BMI levels in children adhering to the MedDiet were significantly lower than those who did not adhere to it (weighted mean difference [WMD] = −0.42 kg/m², 95% CI: −0.61, −0.23, <i>I</i>² = 65.15%, <i>p</i> &lt; 0.001). Additionally, results indicated that children with overweight had a lower mean adherence score compared to children with normal weight (WMD = −0.44 scores, 95% CI: −0.76, −0.12, <i>I</i>² = 85.95%, <i>p</i> &lt; 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This meta-analysis highlights that greater adherence to the MedDiet was associated with lower odds of obesity among children and adolescents. However, these findings should be interpreted cautiously because the evidence was entirely cross-sectional, heterogeneity was substantial across several pooled analyses and some estimates were sensitive to exclusion of individual studies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"21 10","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149068447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitochondrial Dysfunction Markers in Paediatric Obesity: DNA Content and Oxidation Damage","authors":"Mailén Rojo,&nbsp;Andrea Liliana Millán,&nbsp;Alejandra Beatriz Duarte,&nbsp;Andrea Elena Iglesias Molli,&nbsp;Gustavo Daniel Frechtel,&nbsp;Gloria Edith Cerrone,&nbsp;Hernán Pérez","doi":"10.1111/ijpo.70153","DOIUrl":"https://doi.org/10.1111/ijpo.70153","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Childhood obesity increases chronic disease risk. Mitochondrial dysfunction, reflected by altered mitochondrial DNA (mtDNA) content and oxidative damage, has been implicated in obesity-related metabolic disorders, but paediatric data remain scarce.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate mtDNA content and oxidation in children with obesity, stratified as metabolically healthy (MHO) or unhealthy (MUO), compared with peers with normal weight (NW).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Cross-sectional study of 114 children aged 7–14 years: NW (<i>n</i> = 37), MHO (<i>n</i> = 40) and MUO (<i>n</i> = 37). mtDNA content was measured by qPCR, and oxidative damage as 8-oxoguanine by FPG-qPCR. Analyses included Student's <i>t</i>-test, one-way ANOVA with Tukey HSD, Pearson's χ² and linear regression adjusted for age, sex and Tanner stage.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Children with obesity showed elevated cardiometabolic risk, lower HDL-c, insulin resistance (IR), inflammation and significantly lower mtDNA content (−30.9%; <i>p</i> = 0.004) compared with NW, with no differences between MHO and MUO. Higher BMI was independently associated with lower mtDNA content (−3.72% per 1 kg/m²; <i>p</i> = 0.003), consistent across pubertal stages. In a multivariable model of metabolic syndrome components, HDL-c was independently associated with mtDNA content (<i>β</i> = 0.33; <i>p</i> = 0.016). Lower mtDNA content was also associated with IR and higher hs-CRP (<i>B</i> = −0.13; <i>p</i> = 0.028). mtDNA oxidation showed only a non-significant trend in obesity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Lower mtDNA content was detectable in MHO and independently associated with HDL-c and subclinical inflammation. The absence of MHO–MUO differences suggests that chronic inflammation and IR, common to both phenotypes, may be the main factors associated with mtDNA variation at this age.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"21 10","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149068439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}