Pediatric Obesity最新文献

{"title":"Leukocyte telomere length and birth characteristics associated with obesity in infancy in a predominantly Latinx cohort.","authors":"Abigail Duque, Jue Lin, Laura Jeliffe-Pawlowski, Kim Coleman-Phox, Larry Rand, Janet M Wojcicki","doi":"10.1111/ijpo.70034","DOIUrl":"10.1111/ijpo.70034","url":null,"abstract":"<p><strong>Background: </strong>Previous studies suggest that in utero exposures may impact future weight gain trajectories in infancy. Leukocyte telomere length (LTL) collected at birth may be an additional variable to test in models for childhood obesity as adult studies suggest that LTL may be predictive of metabolic disease.</p><p><strong>Methods: </strong>Using a primarily Latinx mother-child longitudinal cohort design, we assessed the relationship between newborn LTL measured via quantitative PCR and obesity at 12 months (WFA ≥ 95th percentile). Secondary outcomes included weight-for-age (WFA) Z scores at 12 months and covariates included birth anthropometrics and maternal prenatal health. Logistic and linear regression models were used to assess independent predictors for infant obesity and WFA Z scores.</p><p><strong>Results: </strong>We followed 302 children until 12 months including 65.89% with Latinx ethnicity and 4.97% had obesity at 12 months. Independent predictors of obesity at 12 months included higher birthweight Z scores (OR 2.24, 1.16, 5.05) and WFA Z scores at 6 months (OR 1.56, 1.19, 2.05). Longer LTL at birth and higher Apgar scores at 5 min were protective (OR 0.04, 95%CI 0.002, 0.79 and OR 0.30, 95%CI 0.13-0.72, respectively). LTL at birth was negatively associated with WFA Z scores at 12 months of age in multivariable models (Coeff = -0.58, 95%CI -1.05, -0.12).</p><p><strong>Conclusions: </strong>LTL at birth may be a marker, in addition to birthweight, that can be used to assess an infant's risk for subsequent obesity. Future studies are needed to better assess and determine possible maternal exposures associated with shorter newborn LTL.</p>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":" ","pages":"e70034"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultra-processed food intake and risk of obesity among schoolchildren aged 8-12 years living in Victoria, Australia.","authors":"Lachlan Clark, Kristy A Bolton, Kathellen E Lacy, Karen Lim, Priscila P Machado, Carley A Grimes","doi":"10.1111/ijpo.70030","DOIUrl":"10.1111/ijpo.70030","url":null,"abstract":"<p><strong>Introduction: </strong>Ultra-processed foods (UPF) are frequently consumed by children, possibly contributing to childhood obesity. It is unknown if UPF consumption among Australian children differentiates by sociodemographic factors.</p><p><strong>Objectives: </strong>To describe schoolchildren's intake of UPF across sexes, age, geographic location and socioeconomic status (SES). To analyse associations between UPF intake and indicators of obesity.</p><p><strong>Methods: </strong>UPF consumption of children aged 8-12 years in Victoria (Australia) was examined using 24-h dietary-recall data classified by the NOVA system. UPF intake was compared across sociodemographic groups. Regression analysis explored the association between UPF intake and BMI z-score, overweight/obesity and abdominal obesity.</p><p><strong>Results: </strong>UPF comprised 47.2% of total energy intake (range 23.7%-72.2%), with no significant differences across sex, age group (8-9 vs. 10-12 years), geographic location or SES. Including all children, there were no associations between UPF intake and obesity indicators. In age-stratified models, among children aged 10-12 years, a 10% increment in the proportion of UPF in the diet (% g/day) was significantly associated with a 0.07 (95% CI 0.01, 0.12) higher body mass index (BMI) z-score and a 19% (odds ratio 1.19, 95% CI 1.07, 1.33) increase in the odds of central obesity. No associations between UPF intake and indicators of obesity were found in the younger 8- to 9-year-old group.</p><p><strong>Conclusions: </strong>UPF contributed greatly to the dietary intake of primary schoolchildren. Among older children, higher intake of UPF was associated with higher BMI z-score and central adiposity. Further longitudinal research in Australian pediatric samples to understand UPF impact upon adiposity outcomes across different stages of childhood is needed.</p>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":" ","pages":"e70030"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does food reward predict changes in weight and body composition during multidisciplinary interventions in adolescents with obesity? Bayesian and frequentist meta-analyses.","authors":"Halim Moore, Julie Siroux, Maud Miguet, Alicia Fillon, Julie Masurier, Graham Finlayson, Bruno Pereira, David Thivel","doi":"10.1111/ijpo.70029","DOIUrl":"10.1111/ijpo.70029","url":null,"abstract":"<p><strong>Background: </strong>A predisposition to elevated food reward may hinder weight loss success during multidisciplinary interventions. However, this has not been consistently demonstrated in adults, nor at all in children.</p><p><strong>Objective: </strong>To test the associations between explicit and implicit food reward and preference at baseline and prospective changes in weight and body composition in adolescents with obesity.</p><p><strong>Methods: </strong>A meta-analysis of 6 clinical trials in adolescents with obesity was undertaken using frequentist and Bayesian linear mixed models. Participants from each study took part in similar 12-week multidisciplinary interventions. Liking and wanting for foods varying in fat content and sweet taste were assessed at enrolment, and both anthropometrics were tracked from enrolment to post-intervention.</p><p><strong>Results: </strong>In a grand sample of N = 132 adolescents with obesity, liking and wanting for high-fat foods did not significantly predict changes in weight or fat mass. However, implicit wanting for sweet foods predicted changes in standardised body and lean mass, such that a greater wanting for sweet foods was associated with greater loss of body (p = 0.039, η²p = 0.05) and lean mass (p < 0.001, η²p = 0.13) in both frequentist and Bayesian analyses.</p><p><strong>Conclusions: </strong>Baseline implicit wanting for sweet (high carbohydrate, low protein), but not energy-dense, foods may be more strongly related to prospective changes in lean mass than fat mass during weight loss in adolescents with obesity. Further research is needed to clarify whether low protein intake can account for this effect.</p>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":" ","pages":"e70029"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical burden of hyperphagia, obesity and health outcomes in paediatric individuals with Bardet-Biedl syndrome: A CRIBBS data analysis.","authors":"Jeremy Pomeroy, Uzoma Okorie, Jesse G Richardson, Ariane Faucher, Raluca Ionescu-Ittu, Francis Vekeman, Caroline Huber, Robert M Haws","doi":"10.1111/ijpo.70026","DOIUrl":"10.1111/ijpo.70026","url":null,"abstract":"<p><strong>Background: </strong>To date, research on the natural history of hyperphagia, weight gain and health outcomes in individuals with Bardet-Biedl syndrome (BBS) has been limited. Understanding these characteristics is important for disease burden management.</p><p><strong>Objectives: </strong>The international Clinical Registry Investigating BBS (CRIBBS) is a registry of individuals with BBS to investigate the severity of hyperphagia, the natural history of weight gain and the frequency of obesity-associated health outcomes in paediatric individuals with BBS.</p><p><strong>Methods: </strong>Paediatric participants (<18 years of age) enrolled in CRIBBS were evaluated to assess weight and weight loss interventions, hyperphagia and the frequency of cardiac, endocrine/diabetic and renal health outcomes.</p><p><strong>Results: </strong>Of 331 children, 81.0% had obesity at baseline and 22.7% reported use of weight loss diet or medication at baseline or later. Among participants with ≥2 weight measurements ≥2 years apart (n = 186), 17.2% had a higher weight classification from the first to the last assessment. Increasing hyperphagia severity was associated with increasing obesity. The prevalence of cardiac, diabetic, endocrine and renal health outcomes increased with obesity class.</p><p><strong>Conclusion: </strong>Hyperphagia and obesity are highly prevalent in children with BBS. Many children with BBS also experience adverse health outcomes. Timely diagnosis and targeted treatment of hyperphagia and obesity are needed.</p>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":" ","pages":"e70026"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A school-based intervention for obesity prevention and management: Effectiveness and determinants of its success. The Feel4Diabetes study.","authors":"Matzourana Argyropoulou, Costas A Anastasiou, Maria Papamichael, Greet Cardon, Stavros Liatis, Jaana Lindstrom, Luis A Moreno, Violeta Iotova, Yuliya Bazdarska, Tsvetalina Tankova, Imre Rurik, Peter Toprzsa, Katja Wikström, Konstantinos Makrilakis, Yannis Manios","doi":"10.1111/ijpo.70025","DOIUrl":"10.1111/ijpo.70025","url":null,"abstract":"<p><strong>Background: </strong>Curbing the rise in overweight and obesity in childhood is of top priority in the public health agenda.</p><p><strong>Objective: </strong>To examine the effectiveness of a 2-year school-based intervention on children's body mass index (BMI) z-score, considering children's baseline weight status, as well as to identify socio-demographic factors that could predict a positive weight outcome.</p><p><strong>Methods: </strong>Data were collected from 9255 children 5-12 years, from six European countries, participating in the Feel4Diabetes study. The intervention group received a lifestyle intervention, aiming to promote a healthy and active lifestyle. Children's anthropometrics were measured at baseline and 2-year follow-up.</p><p><strong>Results: </strong>Children with overweight, but not with obesity, at baseline randomized in the intervention group had a higher reduction in BMI z-scores compared to the control group. In logistic regression models, older age, female sex, overweight or obesity increased the likelihood of any decrease in BMI z-score in the intervention group. Mother's obesity and a lower family income were associated with a decreased probability of a positive weight outcome from the intervention.</p><p><strong>Conclusions: </strong>The Feel4Diabetes school-based intervention demonstrated that it could effectively improve the BMI z-score among children with overweight, but not with obesity. Family's characteristics (mother's weight and family income) may affect the effectiveness of such interventions and should be considered in relevant public health efforts.</p>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":" ","pages":"e70025"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preferences and willingness to pay for early childhood healthy lifestyle initiative outcomes: A discrete choice experiment.","authors":"Vicki Brown, Brittany J Johnson, Thomas Lung, Alison Hayes, Karen Matvienko-Sikar, Konsita Kuswara, Elisabeth Huynh","doi":"10.1111/ijpo.70033","DOIUrl":"10.1111/ijpo.70033","url":null,"abstract":"<p><strong>Background: </strong>Understanding stakeholder preferences and values for early childhood initiatives to support healthy diets, physical activity and reduce sedentary behaviour is key for effective intervention design and resource allocation. This study aims to estimate the preferences for and value of outcomes from the perspectives of parents/caregivers of Australian children aged from birth to 5 years.</p><p><strong>Methods: </strong>Discrete choice experiment, 466 parent/caregivers recruited from online platform. Participants selected between two healthy lifestyle initiatives or a \"neither\" option. Initiatives were described by attributes including cost, participation and outcomes. Mixed multinomial logistic models were used to determine preferences and willingness-to-pay per annum framed as an increase in income taxes.</p><p><strong>Results: </strong>Effect on diet was the most important influence on parent/caregiver choice to participate (p < 0.01), followed by effect on physical activity (p < 0.01), wellbeing (p < 0.01) and healthy growth (p < 0.01). Parents/caregivers were less sensitive to cost for initiatives aimed at specific children (e.g., targeted initiatives for a priority population). Willingness-to-pay estimates ranged from AUD$176 for improved wellbeing to $219 for healthier diets.</p><p><strong>Conclusions: </strong>Results suggest that leveraging the potential for healthier diets, followed by healthier physical activity behaviours, as a key benefit of participation may be particularly attractive to parents/caregivers. In addition, some level of equity preference could be acceptable to parents/caregivers in the allocation of scarce resources.</p>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":" ","pages":"e70033"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144281832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Randomised Controlled Trial Testing a Behavioural Intervention Program for the Prevention of Type 2 Diabetes Among American Indian Youth: The Tribal Turning Point Study.","authors":"Catherine C Cohen, Dana Dabelea, Madhumita Sinha, Alan M Delamater, Deborah H Glueck, Christine W Hockett, Mary A Hoskin, Spero Manson, Elizabeth Mayer-Davis, Phoutdavone Phimphasone-Brady, Jeffrey C Powell, Dorota Wasak, Alexandra V Stamatoiu, Rachel I Steinberg, Katherine A Sauder","doi":"10.1111/ijpo.70053","DOIUrl":"10.1111/ijpo.70053","url":null,"abstract":"<p><strong>Background: </strong>American Indian youth experience a high risk of overweight/obesity and type 2 diabetes.</p><p><strong>Objectives: </strong>To evaluate the effect of a behavioural intervention on diabetes risk factors among American Indian youth with overweight/obesity.</p><p><strong>Methods: </strong>Between 2018 and 2023, youth (7-10 years) were randomised to the tribal turning point (TTP) intervention (n = 87) or control arm (n = 95). Community coaches delivered the core intervention in the first 6 months (10 group classes, 4 individual sessions with motivational interviewing) followed by the booster intervention in the second 6 months (2 group classes, 3 individual sessions). The control arm received 4 health/safety classes over 12 months. Data were collected at baseline, 6, and 12 months. Co-primary outcomes were 12-month change in BMI and fasting insulin.</p><p><strong>Results: </strong>There were no significant differences by randomization for either primary outcome at 12 months. Among youth who completed 6-month assessments before the COVID-19 pandemic, the TTP intervention, compared to the control arm, was associated with significantly decreased change values for age/sex-adjusted BMI z-scores (p = 0.028) and waist circumference (p = 0.040) at 6 months.</p><p><strong>Conclusions: </strong>In this trial among American Indian youth spanning the COVID-19 pandemic, the TTP intervention yielded short-term improvements on obesity measures but only in the subset who participated before the pandemic.</p>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":" ","pages":"e70053"},"PeriodicalIF":2.7,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144937369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Application of Children's Sex- and Age-Specific Fat-Mass and Muscle-Mass Reference Curves From Dual-Energy X-Ray Absorptiometry Data for Predicting Cardiometabolic Risk.","authors":"Stephanie Tanasia Saputra, Andraea Van Hulst, Mélanie Henderson, Simone Brugiapaglia, Claudia Faustini, Lisa Kakinami","doi":"10.1111/ijpo.70051","DOIUrl":"https://doi.org/10.1111/ijpo.70051","url":null,"abstract":"<p><strong>Background: </strong>A dual-energy x-ray absorptiometry (DXA)-derived phenotype classification based on fat mass and muscle mass has been developed for adults. We extended this to a paediatric population.</p><p><strong>Methods: </strong>Children's (≤ 17 years) DXA data in NHANES (n = 6120) were used to generate sex- and age-specific deciles of appendicular skeletal muscle mass index and fat mass index with the Lambda Mu Sigma method. Four phenotypes (high [H] or low [L], adiposity [A] and muscle mass [M]: HA-HM, HA-LM, LA-HM, LA-LM) were identified based on being above/below the median compared to same-sex and same-age peers. These reference curves were applied to the QUALITY cohort (n = 630, 8-10 years of age in 2005) to assess whether the phenotypes correctly identified cardiometabolic risk at baseline, follow-up (2008-2010), and their longitudinal changes. Multiple linear regression models were adjusted for age, sex, and Tanner's stage.</p><p><strong>Results: </strong>Compared to the LA-HM reference group, the HA-HM phenotype was associated with less favourable HDL, triglycerides, and HOMA-IR at baseline and first follow-up, but not in their changes. The HA-LM phenotype was associated with less favourable HOMA-IR at baseline and first follow-up.</p><p><strong>Conclusions: </strong>Results suggest that phenotypes based on fat and muscle mass may have clinical utility in children and should be further investigated.</p>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":" ","pages":"e70051"},"PeriodicalIF":2.7,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144937306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Sleep Loss on Screen Time in Children: Secondary Analyses of a Randomised Crossover Trial Using Objective Measures of Screen Time.","authors":"R F Jackson, K A Meredith-Jones, J J Haszard, B C Galland, S Morrison, M Jaques, R W Taylor","doi":"10.1111/ijpo.70050","DOIUrl":"https://doi.org/10.1111/ijpo.70050","url":null,"abstract":"<p><strong>Background: </strong>How reduced sleep impacts screen time in children is unclear.</p><p><strong>Objectives: </strong>To explore how reduced sleep impacts objectively measured screen use.</p><p><strong>Methods: </strong>One hundred and five children (8-12 years) with caregiver-reported sleep of 8-11 h/night were randomised to 7 nights sleep extension (go to bed 1 h earlier) or sleep restriction (bed 1 h later) in a crossover trial with a 7-night washout between conditions. Sleep and time awake were measured using waist-worn accelerometry (ActiGraph wGT3X-BT) and screen time using wearable cameras (Brinno TLC130 Timelapse) and questionnaires. Camera images were coded as time spent on screens (raw data), including imputation for blocked images (Rules 1 and 2). Within-person differences (95% CI) were calculated in those with matched camera data across sleep intervention weeks, in minutes and as percentage of awake time.</p><p><strong>Results: </strong>Screen time before school or on weekends did not differ in the 49 children (10.4 years, 51% female, 41% overweight, 78% European) with suitable camera data. After school, children appeared to have similar screen time using raw data (median difference; 25th, 75th percentiles: 18.7 min; -10.2, 72.5), but greater screen time during sleep restriction compared with extension after allowance for blocked images (Rule 2: 66.3 min; 7.5, 102.9 or 6% of awake time; 0.5, 10.0). Parents (n = 98) reported greater total screen use in children during the sleep restriction week (mean difference; 95% CI: 16.8 min; 1.8, 31.8).</p><p><strong>Conclusions: </strong>In this secondary analysis, getting less sleep appeared to increase screen time in children during the weekday afternoon and evening hours, compared to when they received more sleep.</p><p><strong>Trial registration: </strong>ACTRN12618001671257 Australian New Zealand Clinical Trials Registry; ANZCTR.</p>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":" ","pages":"e70050"},"PeriodicalIF":2.7,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144937349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trajectory and Trend of Weight Status, Emotional Wellbeing and Sleep From Infancy to Childhood to Adolescence in Scotland: An Analysis of Growing up in Scotland Birth Cohort 1","authors":"Emma Louise Gale,&nbsp;Joanne Elizabeth Cecil,&nbsp;Andrew James Williams","doi":"10.1111/ijpo.70049","DOIUrl":"10.1111/ijpo.70049","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Childhood obesity interventions often overlook sleep and emotional wellbeing, though research shows both are associated with weight status across childhood. The timing of their co-development and the most effective point for intervention remain poorly understood. The aim of this study was to examine the trajectories of sleep, weight status and emotional wellbeing using the Growing Up in Scotland birth cohort 1 dataset.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study conducted secondary data analyses from sweeps 1–10 (10 months-14 years). Sleep was assessed through main-carer and self-reports, covering duration, bedtime, fragmentation, insomnia symptoms and oversleeping. Weight status was evaluated using BMI percentiles from objective height and weight measurements. Emotional wellbeing was evaluated using the emotional symptoms subscale of the Strengths and Difficulties Questionnaire. Trajectories were categorised as stable, improving, or declining for wellbeing; stable, obesogenic or leptogenic for weight; and compared against age-specific recommendations for sleep.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Analyses from 4157 participants (50.2% male) showed that sleep duration declined with age, falling significantly below age-specific recommendations between 8 and 14 years. Bedtimes became later and more variable between 8 and 10 years, with insomnia symptoms and delayed sleep onset common by age 14. Obesogenic or fluctuating weight trajectories were observed in 51.2% of participants. Emotional wellbeing declined notably between 10 and 14 years.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Declines in sleep and emotional wellbeing coincided with rising obesity rates between ages 10 and 12. Targeted intervention between ages 8 and 10 years offers a critical opportunity to mitigate risks of obesity, poor sleep and declining emotional wellbeing before adolescence.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"20 11","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ijpo.70049","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144833569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}