Flávio Eduardo da Silva de Carvalho , Felipe de Oliveira Salle , Karen Apellanis Borges , Karine Batista Machado de Carvalho , Thales Quedi Furian , Carlos Tadeu Pippi Salle
{"title":"Carcass condemnation prediction using artificial neural networks in poultry slaughterhouses","authors":"Flávio Eduardo da Silva de Carvalho , Felipe de Oliveira Salle , Karen Apellanis Borges , Karine Batista Machado de Carvalho , Thales Quedi Furian , Carlos Tadeu Pippi Salle","doi":"10.1016/j.rvsc.2025.105884","DOIUrl":"10.1016/j.rvsc.2025.105884","url":null,"abstract":"<div><div>Challenges related to carcass quality and high condemnation rates result in significant economic losses. Also, the rigorous inspection of broiler carcasses is essential to ensure sanitary standards and food safety in industrial poultry production. To enhance traditional inspection methods, this study evaluated the use of artificial neural networks (ANN) to predict conditions and condemnations in broiler chickens. Data from 3370 flocks inspected at a poultry company in southern Brazil between 2019 and 2022 were analyzed and 16 output variables were modeled using NeuroShell Predictor software. Nine models (56.25 %) were classified as good or excellent, with the models for “partial and total condemnation” presenting coefficients of determination (R<sup>2</sup>) > 0.93 and correlation coefficients close to 0.96, reflecting strong predictive performance and consistency between the predicted and actual values. Conditions involving more complex visual diagnoses such as cachexia, ascites, and cellulitis resulted in less accurate models. These findings suggest that ANNs can be useful tools to support postmortem inspection, reducing economic losses and improving the efficiency and sustainability of the poultry production chain. Nonetheless, because the data were sourced from a single production system, model applicability is limited to this context. Further studies using external datasets from other companies are recommended to assess model generalization under different production conditions.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"196 ","pages":"Article 105884"},"PeriodicalIF":1.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seavchou Laut , Saranya Poapolathep , Narumol Klangkaew , Napasorn Phaochoosak , Tara Wongwaipairoj , Elena Badillo , Pedro Marin , Elisa Escudero , Mario Giorgi , Amnart Poapolathep
{"title":"Pharmacokinetics of carprofen in Siamese crocodiles (Crocodylus siamensis)","authors":"Seavchou Laut , Saranya Poapolathep , Narumol Klangkaew , Napasorn Phaochoosak , Tara Wongwaipairoj , Elena Badillo , Pedro Marin , Elisa Escudero , Mario Giorgi , Amnart Poapolathep","doi":"10.1016/j.rvsc.2025.105886","DOIUrl":"10.1016/j.rvsc.2025.105886","url":null,"abstract":"<div><div>Carprofen (CAR) is an NSAID commonly used in veterinary medicine that preferentially inhibits cyclooxygenase-2 (COX-2), thereby mitigating inflammation and pain while minimizing adverse effects linked to cyclooxygenase-1 (COX-1) inhibition. This study characterizes the pharmacokinetics of CAR in Siamese crocodiles (<em>Crocodylus siamensis</em>) and was conducted at an ambient temperature range of 27–30 °C following single intravenous (IV) or intramuscular (IM) administration at 2 mg/kg, and IM administration at 4 mg/kg. Plasma concentrations were determined using a validated high-performance liquid chromatography method with ultraviolet detection (HPLC-UV). Pharmacokinetic parameters were derived using non-compartmental analysis (NCA). After IM administration, CAR exhibited dose-dependent increases in peak plasma concentrations (C<sub>max</sub>: 4.15 μg/mL at 2 mg/kg; 6.64 μg/mL at 4 mg/kg). The elimination half-life (t<sub>1/2λz</sub>) was prolonged following IM injection (37.00–40.22 h) compared to IV administration (25.69 h), suggesting flip-flop kinetics. The volume of distribution (Vd) ranged from 0.43 to 0.68 L/kg. The IM bioavailability (F) was calculated as 123.75 % at 2 mg/kg and 94.96 % at 4 mg/kg, potentially reflecting overestimation due to between-group variability in clearance, absence of a cross-over design, or factors such as analytical variation, vehicle effects, or lymphatic absorption. Plasma protein binding ranged from 73 % to 82 %. These findings indicate sustained systemic exposure and high bioavailability of CAR in <em>C. siamensis</em>, supporting its potential as a long-acting analgesic. Future studies should assess pharmacodynamic responses and therapeutic efficacy in clinical settings to optimize dosing regimens.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"196 ","pages":"Article 105886"},"PeriodicalIF":1.8,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145019279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Véronique Bernier Gosselin , Vincent Perreten , Alexandra Collaud , Gertraud Schüpbach-Regula , Mireille Meylan
{"title":"Antimicrobial resistance in Escherichia coli isolates from the calf environment on Swiss dairy farms","authors":"Véronique Bernier Gosselin , Vincent Perreten , Alexandra Collaud , Gertraud Schüpbach-Regula , Mireille Meylan","doi":"10.1016/j.rvsc.2025.105893","DOIUrl":"10.1016/j.rvsc.2025.105893","url":null,"abstract":"<div><div>Antimicrobial resistance (AMR) in the intestinal commensal flora of dairy calves is acquired during the first weeks of life. It has been hypothesized that one of the sources of colonization for such bacterial strains is the calf environment, whereas antimicrobial exposure of the calves plays a role in the selection and maintenance of AMR in the flora. The objectives of this cross-sectional observational study were to explore the associations between AMR and multidrug resistance (MDR; resistance to ≥ 3 drug classes) of <em>Escherichia coli</em> isolated from calves' pens and herd-level factors including quantitative antimicrobial use (AMU) on 60 Swiss dairy farms. Two swabs of calf pens' walls were collected on each farm, and two <em>E. coli</em> isolates from each swab were tested for antimicrobial susceptibility by broth microdilution. Among 240 isolates, the proportion showing no AMR was 57.9 %. The proportion of MDR isolates was 31.3 % and at least one MDR isolate was found on 50 % of the farms. Higher odds of AMR were associated with a producer-estimated incidence of calf pneumonia > 10 % (OR 17.3, 95 % CI 2.5–118.4). The introduction of cattle from ≥ 2 farms during the previous year was associated with increased odds of MDR (OR 12.3, 95 % CI 2.0–75.7). Multidrug-resistant <em>E. coli</em> were common in the calf environment on Swiss dairy farms. Our results suggest that in addition to antimicrobial stewardship, farm management factors including biosecurity practices should be considered in the investigation and prevention of the spread of AMR.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"196 ","pages":"Article 105893"},"PeriodicalIF":1.8,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145061142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eduarda Ribeiro Braga, Ana Karolina Panneitz, Fernando Antônio Moreira Petri, Luís Guilherme de Oliveira
{"title":"Prevalence of porcine circoviruses (PCV2 and PCV3) in slaughtered pigs with different pleurisy lesions score: Coinfections with Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, and Pasteurella multocida","authors":"Eduarda Ribeiro Braga, Ana Karolina Panneitz, Fernando Antônio Moreira Petri, Luís Guilherme de Oliveira","doi":"10.1016/j.rvsc.2025.105892","DOIUrl":"10.1016/j.rvsc.2025.105892","url":null,"abstract":"<div><div>Circovirus porcine (PCV) is a widespread pathogen in swine, consisting of four species: PCV1, PCV2, PCV3, and PCV4. Coinfection with other pathogens exacerbates the severity of Porcine Respiratory Disease Complex (PRDC), leading to significant economic losses. In Brazil, pleurisy lesions in pigs, often due to chronic inflammation from bacterial, viral, and environmental factors, are a major economic concern. This study aimed to detect PCV2 and PCV3 in PRDC by identifying these viruses in lung and pleural samples from pigs with varying degrees of pleurisy lesions. A total of 130 lung and pleural samples were collected from a slaughterhouse and analyzed using the Slaughterhouse Pleurisy Evaluation System (SPES). The qPCR results showed that 63.9 % of lung samples tested positive for PCV2, while 29.2 % were positive for PCV3. In pleural samples, 30.7 % were positive for PCV2 and 37.7 % for PCV3. Additionally, other pathogens, including <em>Mycoplasma hyopneumoniae</em> (Mhyo), <em>Actinobacillus pleuropneumoniae</em> (APP), and <em>Pasteurella multocida</em> (PM), were also detected in both lung and pleural samples. Coinfections were frequently observed in both tissues. Sequencing revealed that the PCV2d variant was the most prevalent; however, we also identified positive samples for PCV2c, a rare finding in Brazil. Our study highlights the complex interactions in PRDC, as well as the presence of PCV2 and PCV3 in this context.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"196 ","pages":"Article 105892"},"PeriodicalIF":1.8,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145019277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Detection of old and recently discovered parvoviruses in apparently healthy dogs in Campania region, Italy","authors":"Gianmarco Ferrara , Michela Chianese , Ugo Pagnini , Giuseppe Iovane , Serena Montagnaro","doi":"10.1016/j.rvsc.2025.105887","DOIUrl":"10.1016/j.rvsc.2025.105887","url":null,"abstract":"<div><div>In addition to the more famous canine parvovirus 2 (CPV-2), the <em>Parvoviridae</em> family includes other viruses able to infect dogs [canine chaphamaparvovirus (CaChPV), canine bocavirus-1 (CBoV-1), and canine bufavirus (CBuV)], whose etiological role is still controversial (mostly identified in animals with diarrhea but also detected in asymptomatic animals). The aim of this work was to evaluate the shedding of these common and recently discovered viruses in the dog population from the Campania region (Italy). A total of 170 feces from apparently healthy dogs were sampled and tested with specific real-time PCR. The prevalences obtained are reported below: 6.5 % (11/117) for CPV-2, 4.1 % (7/170) for CaChPV, 11.8 % (20/170) for CBoV-1, and 7.6 % (13/170) for CBuV. The analysis of risk factors found a greater risk of parvoviruses detection for animals of stray origin, with an altered fecal score, and those living outdoors. Considering single parvoviruses, we found a significantly higher prevalence of CBoV in animals with impaired fecal scores and in dogs living outdoors. The detection of CaChPV in fecal samples was correlated to the origin (stray) of the dog.</div><div>We also evaluated the changes in the fecal microbiota in positive dogs, observing a reduction of <em>Bacteroides</em> and an increase of <em>Enterobacteriaceae</em> (up to 70 %) in CPV-2-positive dogs. Only minor changes, however, were observed in animals positive for other parvoviruses.</div><div>Moreover, we established that the shedding of these parvoviruses did not affect the result of rapid direct assays commonly used in clinical routine diagnostics for CPV-2.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"196 ","pages":"Article 105887"},"PeriodicalIF":1.8,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145019278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A cohort study of nutritional secondary hyperparathyroidism in horses in Hawaiʻi","authors":"Laszlo M. Hunyadi , Emily A. Sundman","doi":"10.1016/j.rvsc.2025.105868","DOIUrl":"10.1016/j.rvsc.2025.105868","url":null,"abstract":"<div><div>Equine nutritional secondary hyperparathyroidism (NSHP, Bighead Disease) is a consequence of diets with abnormal calcium: phosphorus ratios. With the widespread availability of fortified feeds and legume forage, the disease has largely disappeared. The Hawaiian Islands are unique in that legume forage is largely unavailable and pastures have high oxalate concentrations. This was a cohort study that included seventeen adult horses imported from the continental US to the Waiki'i region, Hawaiʻi that grazed on kikuyu grass pastures. Plasma ionized calcium and parathyroid hormone concentrations at baseline and after eight months were evaluated. Calcium supplementation was provided via gastroprotectant formulations with Group 1 (eight horses) receiving supplement 1 and Group 2 (five horses) receiving supplement 2. 8/17 horses were normal and 9/17 horses were diagnosed with NSHP. In Group 1, 1 NSHP horse resolved, 4 NSHP horses remained affected, 2 non-NSHP horses remained unaffected, and 1 non-NSHP horse developed disease. In Group 2, 2 NSHP horses resolved, 1 NSHP horse remained affected, and 2 non-NSHP horses remained unaffected. A statistically significant difference between treatment cohorts was found in post-treatment ionized calcium (<em>p</em>-value =0.0063) and parathyroid hormone (p-value =0.0236) concentrations. The results of this study demonstrate that NSHP remains a common disease in regions without consistent access to fortified feeds and with high oxalate grasses leading to oxalate toxicosis. Calcium supplementation may be effective in some horses, but continued monitoring is required.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"196 ","pages":"Article 105868"},"PeriodicalIF":1.8,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cristina Higueras , Ángel Sainz , Mercedes García-Sancho , Fernando Rodríguez-Franco , Ana Isabel Rey
{"title":"Associations between hematological variables and fecal fatty acid profile in dogs with chronic inflammatory enteropathies","authors":"Cristina Higueras , Ángel Sainz , Mercedes García-Sancho , Fernando Rodríguez-Franco , Ana Isabel Rey","doi":"10.1016/j.rvsc.2025.105890","DOIUrl":"10.1016/j.rvsc.2025.105890","url":null,"abstract":"<div><div>The diagnosis of food-responsive enteropathy (FRE) and immunosuppressant-responsive enteropathy (IRE) relies on dietary response followed by other invasive methods, since the pathogenesis is unknown. This study aimed firstly, to evaluate differences in main blood cells, biochemical profile, and hematological inflammatory indices between (FRE) and (IRE) dogs; and secondly, to study and quantify possible associations between these blood variables and the fecal lipid profile to better understand both diseases. Dogs with IRE showed higher platelet counts, plateletcrit, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio, and systemic immune-inflammation index (SII) compared to dogs with FRE. Lymphocytes correlated with C16:1n-7 and the C16:1n-7/C16:0 ratio, with significant linear responses differing between FRE and IRE dogs. Positive correlations between fecal fat levels and immune cells or systemic indices of inflammation were observed. Acetic acid (C2) correlated and followed a significant linear response with platelet counts, and the SII index. Fecal C2 levels higher than 2 mM were associated with platelet counts within the reference range in FRE dogs; whereas the opposite was observed in IRE. Blood glucose and fecal short-chain fatty acids also presented significant correlations, quantified by regression equations in FRE dogs. Significant changes were found in NLR as fecal isoC15:0 levels increased, differing between FRE and IRE dogs. This research confirms that systemic changes in FRE and IRE dogs are directly related to the metabolism of fatty acids. Combining the hemogram or inflammatory indices with fecal fatty acids would allow these two enteropathies to be distinguished more accurately and establish a more appropriate dietary treatment.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"196 ","pages":"Article 105890"},"PeriodicalIF":1.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tatiana Geraissate Gorenstein , Pedro Antônio Bronhara Pimentel , Fabíola de Oliveira Paes Leme , Rita Carolina Figueiredo Duarte , Rodrigo dos Santos Horta
{"title":"Hemostatic evaluation in dogs with lymphoma – Systematic review","authors":"Tatiana Geraissate Gorenstein , Pedro Antônio Bronhara Pimentel , Fabíola de Oliveira Paes Leme , Rita Carolina Figueiredo Duarte , Rodrigo dos Santos Horta","doi":"10.1016/j.rvsc.2025.105885","DOIUrl":"10.1016/j.rvsc.2025.105885","url":null,"abstract":"<div><h3>Background</h3><div>Lymphoma is characterized by clonal proliferation of malignant lymphocytes and it is the most common hematopoietic cancer in dogs. Affected patients may exhibit increased thrombotic risk due to cancer-associated dysregulation of hemostatic pathways, including tissue factor overexpression in tumor stroma, activation of plasminogen inhibitors and coagulation proteases and systemic inflammation.</div></div><div><h3>Objectives</h3><div>This study aimed to evaluate the impact of lymphoma on hemostatic function in canine patients.</div></div><div><h3>Methods</h3><div>This review was elaborated in accordance with the Cochrane Handbook for Systematic Reviews (v6.3, 2022). Eligibility criteria encompassed original studies, published in databases, 1960–2024, assessing hemostatic variables in canine patients with confirmed diagnosis of lymphoma. Analyzed parameters included: platelet count, prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen, antithrombin (AT), fibrinogen degradation products (FDPs), D-dimer concentration, platelet aggregation and viscoelastic testing.</div></div><div><h3>Results</h3><div>Dogs with lymphoma demonstrated platelet counts, aPTT, and AT activity within reference intervals. Increased viscoelasticity and elevated FDPs/D-dimer levels, indicating hypercoagulability.</div></div><div><h3>Conclusions</h3><div>Canine lymphoma is linked to an increased thrombotic risk, reflected by hypercoagulable profiles and elevated FDPs and D-dimers, likely driven by tumor-associated procoagulant activity and inflammation. Platelet dynamics are variable and influenced by chemotherapy, and comparisons are limited by lymphoma heterogeneity and study variability. Future research should standardize lymphoma classification, monitor hemostatic changes longitudinally, and correlate biomarkers with clinical outcomes to improve risk stratification and therapy.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"196 ","pages":"Article 105885"},"PeriodicalIF":1.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caio Afonso Santos Malta , Alefe Luiz Caliani Carrera , Thiago André Salvitti Sá Rocha , Bruno Watanabe Minto , Luís Gustavo Gosuen Gonçalves Dias
{"title":"Comparison of compressive forces generated by dynamic compression angle-stable interlocking nail versus traditional dynamic compression plate and locking compression plate","authors":"Caio Afonso Santos Malta , Alefe Luiz Caliani Carrera , Thiago André Salvitti Sá Rocha , Bruno Watanabe Minto , Luís Gustavo Gosuen Gonçalves Dias","doi":"10.1016/j.rvsc.2025.105881","DOIUrl":"10.1016/j.rvsc.2025.105881","url":null,"abstract":"<div><div>The aim of this study was to compare the compressive forces generated by Dynamic Compression Angle-Stable Interlocking Nail (DCASIN) with those of traditional Dynamic Compression Plates (DCP) and Locking Compression Plates (LCP) using synthetic diaphyseal bone models (SDBM). Three groups were established based on the fixation method (G-DCASIN, G-DCP, and G-LCP), with implants fixed to SDBM simulating a transverse fracture, comprising 10 repetitions per group. A strain-gauge load cell was positioned in the SDBM gap to measure compressive forces in kilograms, recorded 30 s after the completion of each group-specific compression technique. For G-DCASIN, the proximal SDBM was compressed against the load cell using the external implantation guide and compression device. For G-DCP and G-LCP, the same-side double loading technique was applied to the proximal SDBM. Compressive forces among groups were compared using the Kruskal-Wallis test followed by Dunn's post-hoc analysis. The mean compressive forces recorded for G-DCASIN, G-DCP, and G-LCP were 22.56 ± 5.1 kg, 27.28 ± 1.86 kg, and 11.65 ± 1.69 kg, respectively. Both G-DCASIN and G-DCP exhibited significantly greater compressive forces compared to G-LCP (<em>p</em> = 0.0013 and <em>p</em> < 0.0001, respectively), whereas G-DCASIN and G-DCP did not differ significantly (<em>p</em> = 0.2228). In this mechanical trial, DCASIN demonstrated the ability to generate interfragmentary compression superior to LCP and comparable to DCP. The combination of compressive capability and angle-stable locking suggests that this model may be a viable option for the treatment of transverse fractures of long bones.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"196 ","pages":"Article 105881"},"PeriodicalIF":1.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144997450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jorge Ortiz-Gutiérrez , Miriam Portero-Fuentes , Hernán Fominaya García , Elena Mínguez-Pereira , Laura Martín-Carrasco , Enrique García Pérez , María Ángeles Daza
{"title":"Determination of the inter-observer and inter-scanner variability in the measurement of the renal resistive and renal pulsatility indices in dogs","authors":"Jorge Ortiz-Gutiérrez , Miriam Portero-Fuentes , Hernán Fominaya García , Elena Mínguez-Pereira , Laura Martín-Carrasco , Enrique García Pérez , María Ángeles Daza","doi":"10.1016/j.rvsc.2025.105882","DOIUrl":"10.1016/j.rvsc.2025.105882","url":null,"abstract":"<div><div>Renal Resistive Index (RRI) and Renal Pulsatility Index (RPI) are currently used in the diagnosis of ureteral obstruction, early diagnosis and follow-up of acute kidney injury, assessment of chronic kidney disease, and evaluation of transplanted kidneys. However, their inter-observer and inter-scanner variability has not been investigated in dogs, limiting the accuracy and clinical applicability of these indices. The objectives of this cross-sectional observational prospective study were to assess the inter-observer and inter-scanner variability of RRI and RPI and to determine whether operator experience influences measurement accuracy. RRI and RPI were measured in the left kidney of 10 client-owned dogs by four different operators with varying levels of experience, using two different ultrasound scanners. The intraclass correlation coefficient (ICC) between the two ultrasound scanners for both RRI and RPI were good to excellent in all four observers (ICC > 0.75 and <em>p</em> < 0.05). Similarly, a good to excellent correlation coefficient was observed between the measurements of the four operators for both indices across each ultrasound scanner (ICC > 0.75 and <em>p</em> < 0.05). These findings indicate that RRI and RPI are feasible and reproducible measurements with good inter-scanner and inter-observer agreement, regardless of operator experience. However, achieving high reproducibility requires adequate training and the use of a standardized protocol with strict but adaptable settings tailored to each patient's characteristics.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"196 ","pages":"Article 105882"},"PeriodicalIF":1.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145004946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}