Research in veterinary science最新文献

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Evaluation of a smartphone-based six‑lead ECG for clinical electrocardiography in cats. 基于智能手机的六导联心电图对猫临床心电图的评估。
IF 1.8 3区 农林科学
Research in veterinary science Pub Date : 2026-05-04 DOI: 10.1016/j.rvsc.2026.106236
L Alibrandi, R Tognetti, V Pellegrini, G Grosso, T Vezzosi
{"title":"Evaluation of a smartphone-based six‑lead ECG for clinical electrocardiography in cats.","authors":"L Alibrandi, R Tognetti, V Pellegrini, G Grosso, T Vezzosi","doi":"10.1016/j.rvsc.2026.106236","DOIUrl":"https://doi.org/10.1016/j.rvsc.2026.106236","url":null,"abstract":"<p><p>Smartphone-based electrocardiographic devices (smECGs) are promising tools for both human and veterinary medicine, as they provide greater portability convenience and ease of use than standard methods. Although six‑lead smECG devices have been studied in dogs, there is currently no research on their application in cats. This prospective observational study thus evaluates a six‑lead smECG device in feline clinical practice. A total of forty cats underwent simultaneous ECG recordings with a standard ECG (stECG) and the six‑lead smECG. Heart rhythm was assessed; heart rate, P- and R-wave amplitudes, wave and interval durations and the QRS mean electrical axis were measured. The Bland-Altman plot and Cohen's κ test were used to assess the agreement between the devices. All smECG traces were evaluable. The smECG showed perfect agreement with the stECG in heart rhythm diagnosis (κ = 1) and QRS axis deviation (κ = 1). No clinically significant differences in heart rate or wave and interval duration were observed between the devices. However, the smECG tended to underestimate the P- and R-wave amplitude. The six‑lead smECG device was easy to use and reliable in cats, providing an accurate assessment of heart rhythm and ECG parameters. This tool shows promise for integration into feline clinical practice.</p>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"208 ","pages":"106236"},"PeriodicalIF":1.8,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147842270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cervical disc disease in whippets: Results of an online survey involving Italian owners and breeders 惠比特犬的颈椎间盘疾病:一项涉及意大利犬主和饲养者的在线调查结果
IF 1.8 3区 农林科学
Research in veterinary science Pub Date : 2026-05-01 Epub Date: 2026-01-25 DOI: 10.1016/j.rvsc.2026.106068
Diletta Dell'Apa , Ezio Bianchi , Luigi Auletta , Mariaelena de Chiara , Fabiana Micieli , Francesco Ferrari , Barbara Lamagna , Maria Pia Pasolini
{"title":"Cervical disc disease in whippets: Results of an online survey involving Italian owners and breeders","authors":"Diletta Dell'Apa ,&nbsp;Ezio Bianchi ,&nbsp;Luigi Auletta ,&nbsp;Mariaelena de Chiara ,&nbsp;Fabiana Micieli ,&nbsp;Francesco Ferrari ,&nbsp;Barbara Lamagna ,&nbsp;Maria Pia Pasolini","doi":"10.1016/j.rvsc.2026.106068","DOIUrl":"10.1016/j.rvsc.2026.106068","url":null,"abstract":"<div><div>Whippet is considered quite a healthy breed. Nonetheless, the perception of some veterinary neurologists is that the occurrence of neurological diseases, especially cervical disc disease (CDD), is frequent in this breed. This study aimed to get information about the prevalence of the most common disorders and conditions affecting the Italian Whippet population, particularly investigating the prevalence of CDD and the perception of the problem by owners and breeders. Owners and breeders included in the Italian Sighthound Club register were invited to answer anonymously an online questionnaire. Descriptive statistics were used for breeder/owner and dog characteristics, and statistical association with the development of CDD were explored. Over 280 Whippets, the overall prevalence of CDD was 7.2% and 29% in Whippets older than 9 years. Whippets older than 9 years were overrepresented in the CDD group (<em>P</em> &lt; 0.0001; O.R. 0.07; 95% CI: 0.02–0.22) compared with the CDD group. These findings confirm the hypothesis that CDD may be a challenging and more prevalent than expected disorder in this breed and health screening programs could be recommended to breeders and owners to assess cervical spine conformation, especially before sporting activity or breeding.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106068"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146081421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
miRNA-mRNA integrative profiling in canine tubulopapillary mammary carcinoma 犬管状乳头状乳腺癌的miRNA-mRNA整合分析。
IF 1.8 3区 农林科学
Research in veterinary science Pub Date : 2026-05-01 Epub Date: 2026-02-17 DOI: 10.1016/j.rvsc.2026.106107
Nayra Cristina Herreira do Valle , Matheus Fujimura Soares , Natália Francisco Scaramele , Amanda de Oliveira Furlan , Maria Fernanda da Silva Lopes , Juliana de Souza Felix , Fernando Vissani Fernandes , Vinicius Aquiles Gomes Zamboni , Igor Luiz Salardani Senhorello , Alexandre Lima de Andrade , Flavia Lombardi Lopes
{"title":"miRNA-mRNA integrative profiling in canine tubulopapillary mammary carcinoma","authors":"Nayra Cristina Herreira do Valle ,&nbsp;Matheus Fujimura Soares ,&nbsp;Natália Francisco Scaramele ,&nbsp;Amanda de Oliveira Furlan ,&nbsp;Maria Fernanda da Silva Lopes ,&nbsp;Juliana de Souza Felix ,&nbsp;Fernando Vissani Fernandes ,&nbsp;Vinicius Aquiles Gomes Zamboni ,&nbsp;Igor Luiz Salardani Senhorello ,&nbsp;Alexandre Lima de Andrade ,&nbsp;Flavia Lombardi Lopes","doi":"10.1016/j.rvsc.2026.106107","DOIUrl":"10.1016/j.rvsc.2026.106107","url":null,"abstract":"<div><div>Canine mammary tumors (CMTs) are the most common neoplasia in intact female dogs. There are different histological subtypes, which are related to tumor behavior and prognosis. Among them, we highlight the tubulopapillary subtype, one of the most prevalent subtypes in female dogs. Although not the most aggressive subtype overall, it is associated with significantly higher lethality compared to other common subtypes, suggesting an underlying dysregulation of gene expression. However, global expression of RNAs in tubulopapillary CMTs is not available in the literature. Here, we analyzed the differential expression of mRNAs and miRNAs of tubulopapillary CMTs (<em>n</em> = 4) and compared them with normal mammary tissues (n = 4) using microarray. We found 842 downregulated and 385 upregulated mRNAs in the CMTs, which corresponded to the enrichment of 10 biological pathways. Also, we found 30 upregulated miRNAs and one downregulated (cfa-miR-345) in CMTs. Among the differentially expressed mRNAs, we identified 360 mRNAs that were targets of the differentially expressed miRNAs, which enriched 23 biological pathways, with the “Endocytosis” pathway being of particular significance. These findings highlight the complex interactions between mRNAs and miRNAs in tubulopapillary CMTs, thereby improving the understanding of the pathophysiology of this CMT subtype and providing targets for functional validation of biomarkers and/or therapeutics.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106107"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146258811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
S-palmitoylation of the viral Nsp10 by ZDHHC7 restricts PRRSV replication but is counteracted by Nsp2, Nsp4 and GP5 ZDHHC7对病毒Nsp10的s -棕榈酰化限制了PRRSV的复制,但被Nsp2、Nsp4和GP5抵消。
IF 1.8 3区 农林科学
Research in veterinary science Pub Date : 2026-05-01 Epub Date: 2026-02-06 DOI: 10.1016/j.rvsc.2026.106102
Huiyuan Jing , Zhifeng Peng , Pandeng Zhao , Erzhen Duan , Jie Liu , Xuyong Zhao , Huawei Li
{"title":"S-palmitoylation of the viral Nsp10 by ZDHHC7 restricts PRRSV replication but is counteracted by Nsp2, Nsp4 and GP5","authors":"Huiyuan Jing ,&nbsp;Zhifeng Peng ,&nbsp;Pandeng Zhao ,&nbsp;Erzhen Duan ,&nbsp;Jie Liu ,&nbsp;Xuyong Zhao ,&nbsp;Huawei Li","doi":"10.1016/j.rvsc.2026.106102","DOIUrl":"10.1016/j.rvsc.2026.106102","url":null,"abstract":"<div><div>Reversible S-palmitoylation, initiated by the Zinc finger aspartate-histidine-histidine-cysteine domain (ZDHHC) proteins and erased by the de-palmitoylases, plays an important role in the antiviral immune pathway. Our previous screening identified ZDHHC7 as a potent restriction factor for PRRSV. However, the mechanisms underlying ZDHHC7-mediated suppression of PRRSV replication remains unclear. Here, we showed that PRRSV RNA replication is impaired by ZDHHC7 in an acyltransferase-dependent manner. This antiviral effect was achieved by S-palmitoylation of Nsp10 (Nonstructural protein 10), which weakened the binding between viral RNA and Nsp10. By cleaving porcine ZDHHC7 at E226, PRRSV Nsp4 impaired the S-palmitoylation of Nsp10, STING, and MAVS. Additionally, the cleaved fragments did not inhibit PRRSV multiplication, whereas the cleavage-resistant mutant ZDHHC7-E226A exhibited enhanced antiviral activity. Finally, we demonstrated that PRRSV Nsp2 and GP5 (glycoprotein 5) induce the transcription of APT1 (Acyl-protein thioesterase 1) through the transcription factor NFATC3 to reverse the S-palmitoylation level of Nsp10. Collectively, this work uncovers the antagonistic strategy employed by PRRSV to dampen the antiviral function of ZDHHC7, which deepens our understanding of the immune evasion mechanisms during PRRSV infection.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106102"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146166478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular surveillance and genetic diversity of Enterohemorrhagic Escherichia coli O157:H7 Pathotypes using MLVA method 应用MLVA法监测肠出血性大肠杆菌O157:H7病原型的分子监测和遗传多样性。
IF 1.8 3区 农林科学
Research in veterinary science Pub Date : 2026-05-01 Epub Date: 2026-02-02 DOI: 10.1016/j.rvsc.2026.106093
Sedigheh Mokhtari , Yahya Tahamtan , Mohammad Kargar , Keyvan Tadayon , Elham Moazamian
{"title":"Molecular surveillance and genetic diversity of Enterohemorrhagic Escherichia coli O157:H7 Pathotypes using MLVA method","authors":"Sedigheh Mokhtari ,&nbsp;Yahya Tahamtan ,&nbsp;Mohammad Kargar ,&nbsp;Keyvan Tadayon ,&nbsp;Elham Moazamian","doi":"10.1016/j.rvsc.2026.106093","DOIUrl":"10.1016/j.rvsc.2026.106093","url":null,"abstract":"<div><h3>Background</h3><div><em>Escherichia coli</em> O157 is a major foodborne pathogen associated with severe human disease, with cattle serving as its primary reservoir, and in this study multilocus variable-number tandem-repeat analysis (MLVA) was applied to investigate the genetic diversity, distribution, and population structure of isolates collected in Fars Province, Iran.</div></div><div><h3>Method</h3><div>This study was performed on 150 swab samples were collected from rectum and carcasses of cattle, sheep and goats and fruit juice in Fars province. Samples were processed following standard bacteriological procedures. MLVA method was performed based on polymerase chain reaction (PCR) by using four variable-number tandem repeat (VNTR).</div></div><div><h3>Results</h3><div>22 isolates were identified as <em>E. coli</em> O157:H7 that 15, 6 and 1 were from cattle, sheep and fruit juice, respectively. By using MLVA technique, 22 isolates were separated into 15 distinct MLVA types. MST algorithm showed five genetically related clusters and by UPGMA method isolates were classified in 3 main cluster and 8 sub clusters.</div></div><div><h3>Conclusion</h3><div>This study showed that MLVA can be used as a valid, inexpensive and rapid method to trace and analyze the phylogenetic relationships between <em>E. coli</em> strains in epidemiological research.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106093"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146158163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From gut health to nutrient digestion and metabolism: An integrative biomarker analysis in nursery pigs 从肠道健康到营养物质消化和代谢:保育猪的综合生物标志物分析。
IF 1.8 3区 农林科学
Research in veterinary science Pub Date : 2026-05-01 Epub Date: 2026-01-26 DOI: 10.1016/j.rvsc.2026.106090
Marina P. Walter , Gabriela M. Galli , Marcos Kipper , Karine L. Takeuti , Ines Andretta
{"title":"From gut health to nutrient digestion and metabolism: An integrative biomarker analysis in nursery pigs","authors":"Marina P. Walter ,&nbsp;Gabriela M. Galli ,&nbsp;Marcos Kipper ,&nbsp;Karine L. Takeuti ,&nbsp;Ines Andretta","doi":"10.1016/j.rvsc.2026.106090","DOIUrl":"10.1016/j.rvsc.2026.106090","url":null,"abstract":"<div><div>This study aimed to explore the relationship between intestinal health biomarkers and nutrient digestion and metabolism in nursery pigs. Thirty-two weaned pigs were individually housed and fed a single experimental diet for 22 days. Feces and urine were collected on days 15 to 21 post-weaning to assess energy and protein digestibility and metabolizability. Blood samples were collected on day 22 to assess intestinal permeability, IgG, and IgA. Fecal samples were collected on the same day to quantify calprotectin, neopterin, lactoferrin, calcium-binding proteins, and fatty acid-binding protein (FABP). All pigs were euthanized on day 22 for intestinal tissue collection to determine villus height, villus width, crypt depth, and villus height-to-crypt depth ratio, thiobarbituric acid reactive substances (TBARS), glutathione S-transferase, protein thiols, resistance to rupture, zonula occludens-1, and occludin. Principal component analysis (PCA), correlation, and classification and regression tree (CART) methods were applied. Fecal calcium-binding proteins and FABP levels were identified in the tree-based models (CART) as key predictors of dry matter digestion. On the other hand, fecal calprotectin and FABP levels were the primary determinants of protein and energy digestibility and metabolizability. Fecal calprotectin levels between 79.4 and 79.6 ng/mL served as the cutoff to distinguish nursery pigs with high and low digestibility in two different CART models. Similarly, the cutoff for FABP levels ranged from 70.5 to 87.4 ng/mL, indicating its role in differentiating groups with high and low efficiency. Our results support the potential of fecal biomarkers as non-invasive indicators of digestibility and metabolism in weaned pigs.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106090"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subacute ivermectin–induced affective dysregulation: Evidence for hippocampal microglial and astrocytic activation 亚急性伊维菌素诱导的情感失调:海马小胶质细胞和星形胶质细胞激活的证据。
IF 1.8 3区 农林科学
Research in veterinary science Pub Date : 2026-05-01 Epub Date: 2026-02-13 DOI: 10.1016/j.rvsc.2026.106105
Mustafa Eser , Cevşen Yazıcı , Ümmühan Kandemir , Umut İrfan Üçel , Mehmet Fatih Bozkurt , Ümide Demir Özkay , Özgür Devrim Can
{"title":"Subacute ivermectin–induced affective dysregulation: Evidence for hippocampal microglial and astrocytic activation","authors":"Mustafa Eser ,&nbsp;Cevşen Yazıcı ,&nbsp;Ümmühan Kandemir ,&nbsp;Umut İrfan Üçel ,&nbsp;Mehmet Fatih Bozkurt ,&nbsp;Ümide Demir Özkay ,&nbsp;Özgür Devrim Can","doi":"10.1016/j.rvsc.2026.106105","DOIUrl":"10.1016/j.rvsc.2026.106105","url":null,"abstract":"<div><div>Ivermectin (IVR) is a semi-synthetic macrocyclic lactone widely used against nematodes. Under physiological conditions, its central nervous system (CNS) penetration is limited by P-glycoprotein–mediated efflux at the blood–brain barrier (BBB). Nevertheless, supratherapeutic dosing, BBB-compromising pathologies, concomitant P-glycoprotein inhibitors, or MDR1 variants can enhance CNS entry and precipitate neurotoxicity. To evaluate behavioural and neuroinflammatory sequelae of subacute exposure, rats received IVR (1, 5, or 10 mg/kg; i.p.) once daily for 21 days. Animals were assessed for motor function (activity cage, Rota-rod), affective behaviour (elevated plus maze, modified forced swim test), and cognition (Morris water maze). Assay validation employed diazepam (1 and 3 mg/kg; i.p.), desipramine (30 mg/kg; i.p.), and piracetam (200 mg/kg; i.p.), administered according to their respective protocols. IVR did not alter motor performance or spatial learning and memory across doses. However, 5 and 10 mg/kg reduced the percentage of open-arm entries and increased immobility, consistent with anxiety- and depression-like phenotypes, respectively. At 10 mg/kg, hippocampal immunohistochemistry revealed increased Iba1 and GFAP immunoreactivity within CA1, indicating microglial and astrocytic activation. Quantitative counts demonstrated no significant change in CA1 neuronal number across treatment groups, implying that the observed glial activation occurred in the absence of detectable neuronal loss. Collectively, our data indicate that subacute, high-dose IVR provokes affective behavioural alterations coupled to hippocampal neuroinflammation, while sparing gross motor function and measurable cognitive performance under the present conditions. These findings underscore caution when administering IVR at elevated doses or in settings that compromise BBB integrity and warrant further mechanistic and time-resolved investigation.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106105"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146220825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Registration, badges, and belonging: Reflections on gender inclusion in the veterinary profession 注册、徽章和归属:关于兽医职业性别包容的思考。
IF 1.8 3区 农林科学
Research in veterinary science Pub Date : 2026-05-01 Epub Date: 2026-02-14 DOI: 10.1016/j.rvsc.2026.106106
Emilian Malek , Erika Abbondati , Daniela Denk , Sarah Kirschner-Kitz , Maria Jose Navarrete Talloni , Roberta Rasotto , Chiara Palmieri
{"title":"Registration, badges, and belonging: Reflections on gender inclusion in the veterinary profession","authors":"Emilian Malek ,&nbsp;Erika Abbondati ,&nbsp;Daniela Denk ,&nbsp;Sarah Kirschner-Kitz ,&nbsp;Maria Jose Navarrete Talloni ,&nbsp;Roberta Rasotto ,&nbsp;Chiara Palmieri","doi":"10.1016/j.rvsc.2026.106106","DOIUrl":"10.1016/j.rvsc.2026.106106","url":null,"abstract":"","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106106"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146228578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Geospatial surveillance of the rabies virus in cattle in Brazil 巴西牛狂犬病毒的地理空间监测。
IF 1.8 3区 农林科学
Research in veterinary science Pub Date : 2026-05-01 Epub Date: 2026-02-09 DOI: 10.1016/j.rvsc.2026.106103
Valdir Vieira da Silva , Denny Parente de Sá Barreto Maia Leite , Pollyanne Raysa Fernandes de Oliveira , Lucilene Martins Trindade Gonçalves , Guilherme Valeriano Silva , Ana Clara Neves dos Santos , Raissa Santana Renovato , Yasmim Victória Santos Pereira , Rafaela Silva Santos , Beatriz Maria de Almeida Braz , Jonatas Campos de Almeida , Rinaldo Aparecido Mota
{"title":"Geospatial surveillance of the rabies virus in cattle in Brazil","authors":"Valdir Vieira da Silva ,&nbsp;Denny Parente de Sá Barreto Maia Leite ,&nbsp;Pollyanne Raysa Fernandes de Oliveira ,&nbsp;Lucilene Martins Trindade Gonçalves ,&nbsp;Guilherme Valeriano Silva ,&nbsp;Ana Clara Neves dos Santos ,&nbsp;Raissa Santana Renovato ,&nbsp;Yasmim Victória Santos Pereira ,&nbsp;Rafaela Silva Santos ,&nbsp;Beatriz Maria de Almeida Braz ,&nbsp;Jonatas Campos de Almeida ,&nbsp;Rinaldo Aparecido Mota","doi":"10.1016/j.rvsc.2026.106103","DOIUrl":"10.1016/j.rvsc.2026.106103","url":null,"abstract":"<div><div>In Brazil, bovine rabies causes significant economic losses and poses a risk to both human and veterinary public health. Its persistence is associated with agricultural expansion, environmental factors, and the presence of reservoirs that favor viral circulation. In this context, spatiotemporal analyses are essential to identify high-risk areas and guide effective surveillance strategies. This study aimed to analyze the spatiotemporal, and temporal trends of bovine rabies in Brazil between 2015 and 2024. An ecological study was conducted using data from the National Animal Health Information System (SIZ), applying spatiotemporal, and temporal trend analyses. A total of 7458 cases were reported during the study period, with higher concentrations in the Southeast (28.26%), South (27.76%), and Central-West (21.99%) regions. The highest incidence risks were observed in the South (8.15/100,000), Southeast (5.69/100,000), and Northeast (2.73/100,000). At the state level, Amapá (81.04/100,000), Paraná (8.51/100,000), Pernambuco (8.41/100,000), Amazonas (8.24/100,000), and São Paulo (7.83/100,000) stood out. <em>Desmodus rotundus</em> plays a central role in the maintenance and transmission of rabies virus to herbivores in Brazil, with case density and records of this species overlapping mainly in Minas Gerais, São Paulo, and Paraná, particularly in areas of pasture, temporary crops, and environmental mosaics. Retrospective analysis identified eight high-risk spatiotemporal clusters, with the primary cluster located in the South and Southeast (2015–2019), showing a relative risk (RR) of 2.86. Prospective analysis revealed five recent clusters, with the primary one located in Paraná and Santa Catarina (2022–2024; RR = 3.88). Joinpoint regression demonstrated an overall decreasing trend in incidence risk (APC: −8.6%). This is the first nationwide study integrating spatiotemporal, and temporal analyses of bovine rabies, highlighting its widespread occurrence across Brazil and identifying strategic areas for strengthening control measures.</div></div><div><h3>Keywords</h3><div>Bovine rabies</div><div>Spatiotemporal analysis</div><div>Epidemiology</div><div>Risk clusters</div><div>Brazil</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106103"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146776496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and distribution of anisakid species in fish from North African marine waters: A systematic review and meta-analysis 北非海域鱼类中茴香类的流行和分布:系统综述和荟萃分析。
IF 1.8 3区 农林科学
Research in veterinary science Pub Date : 2026-05-01 Epub Date: 2026-02-23 DOI: 10.1016/j.rvsc.2026.106123
Amir Nahal
{"title":"Prevalence and distribution of anisakid species in fish from North African marine waters: A systematic review and meta-analysis","authors":"Amir Nahal","doi":"10.1016/j.rvsc.2026.106123","DOIUrl":"10.1016/j.rvsc.2026.106123","url":null,"abstract":"<div><div>Foodborne parasites remain a concern for human health. Among marine parasites, anisakid nematodes are notable species frequently detected in marketable fish. This study aimed to estimate the prevalence of anisakid species in fish caught along the coasts of North African countries.</div><div>A systematic literature review was carried out using two electronic databases, in accordance with PRISMA guidelines. Forty studies published between 2006 and 2024 were included in the meta-analysis. Data were analyzed using the meta package in R software, employing a random-effects model.</div><div>The overall pooled prevalence of anisakid species was 32.12% (95% CI 20.53–44.91). Molecular methods identified five <em>Anisakis</em> species and <em>Skrjabinisakis physeteris</em>. Furthermore, the detection of <em>Contracaecum quadripapillatum</em> and <em>Phocanema decipiens</em> indicated the occurrence of other Anisakidae genera not previously documented in North African coastal ecosystems.</div><div>The pooled prevalence of anisakidosis was 35.48% (95% CI 23.37–48.6).while the prevalence of Anisakinae species varied depending on the year, country, fishing area, fish habitat and fish species. The highest prevalence was recorded between 2011 and 2015 (58.14%). Morocco and Libya showed the highest infection rates, whereas Algeria had the lowest (9.74%). The Atlantic coast exhibited the highest regional prevalence (53.69%). Pelagic fish showed greater infection levels (33.54%) than demersal species. Anisakinae species were reported in 44 fish species, with <em>Trachurus trachurus</em> being the most frequently examined (31.22%).</div><div>The widespread distribution of anisakid species in marine fish across North Africa underscores important public health concerns and highlights the necessity for ongoing monitoring and molecular characterization in the region.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106123"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147309617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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