Research in veterinary science最新文献

{"title":"Prevalence and distribution of anisakid species in fish from North African marine waters: A systematic review and meta-analysis","authors":"Amir Nahal","doi":"10.1016/j.rvsc.2026.106123","DOIUrl":"10.1016/j.rvsc.2026.106123","url":null,"abstract":"<div><div>Foodborne parasites remain a concern for human health. Among marine parasites, anisakid nematodes are notable species frequently detected in marketable fish. This study aimed to estimate the prevalence of anisakid species in fish caught along the coasts of North African countries.</div><div>A systematic literature review was carried out using two electronic databases, in accordance with PRISMA guidelines. Forty studies published between 2006 and 2024 were included in the meta-analysis. Data were analyzed using the meta package in R software, employing a random-effects model.</div><div>The overall pooled prevalence of anisakid species was 32.12% (95% CI 20.53–44.91). Molecular methods identified five <em>Anisakis</em> species and <em>Skrjabinisakis physeteris</em>. Furthermore, the detection of <em>Contracaecum quadripapillatum</em> and <em>Phocanema decipiens</em> indicated the occurrence of other Anisakidae genera not previously documented in North African coastal ecosystems.</div><div>The pooled prevalence of anisakidosis was 35.48% (95% CI 23.37–48.6).while the prevalence of Anisakinae species varied depending on the year, country, fishing area, fish habitat and fish species. The highest prevalence was recorded between 2011 and 2015 (58.14%). Morocco and Libya showed the highest infection rates, whereas Algeria had the lowest (9.74%). The Atlantic coast exhibited the highest regional prevalence (53.69%). Pelagic fish showed greater infection levels (33.54%) than demersal species. Anisakinae species were reported in 44 fish species, with <em>Trachurus trachurus</em> being the most frequently examined (31.22%).</div><div>The widespread distribution of anisakid species in marine fish across North Africa underscores important public health concerns and highlights the necessity for ongoing monitoring and molecular characterization in the region.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106123"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147309617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular surveillance and genetic diversity of Enterohemorrhagic Escherichia coli O157:H7 Pathotypes using MLVA method","authors":"Sedigheh Mokhtari ,&nbsp;Yahya Tahamtan ,&nbsp;Mohammad Kargar ,&nbsp;Keyvan Tadayon ,&nbsp;Elham Moazamian","doi":"10.1016/j.rvsc.2026.106093","DOIUrl":"10.1016/j.rvsc.2026.106093","url":null,"abstract":"<div><h3>Background</h3><div><em>Escherichia coli</em> O157 is a major foodborne pathogen associated with severe human disease, with cattle serving as its primary reservoir, and in this study multilocus variable-number tandem-repeat analysis (MLVA) was applied to investigate the genetic diversity, distribution, and population structure of isolates collected in Fars Province, Iran.</div></div><div><h3>Method</h3><div>This study was performed on 150 swab samples were collected from rectum and carcasses of cattle, sheep and goats and fruit juice in Fars province. Samples were processed following standard bacteriological procedures. MLVA method was performed based on polymerase chain reaction (PCR) by using four variable-number tandem repeat (VNTR).</div></div><div><h3>Results</h3><div>22 isolates were identified as <em>E. coli</em> O157:H7 that 15, 6 and 1 were from cattle, sheep and fruit juice, respectively. By using MLVA technique, 22 isolates were separated into 15 distinct MLVA types. MST algorithm showed five genetically related clusters and by UPGMA method isolates were classified in 3 main cluster and 8 sub clusters.</div></div><div><h3>Conclusion</h3><div>This study showed that MLVA can be used as a valid, inexpensive and rapid method to trace and analyze the phylogenetic relationships between <em>E. coli</em> strains in epidemiological research.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106093"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146158163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavioral and welfare responses of broiler chickens to plastic-grid flooring, zeolite, and wood shavings litter systems","authors":"Mehmet Kaya,&nbsp;Evrim Dereli Fidan,&nbsp;Hayriye Değer Oral Toplu,&nbsp;Solmaz Karaarslan,&nbsp;Mehmet Kenan Türkyilmaz,&nbsp;Ahmet Nazligül","doi":"10.1016/j.rvsc.2026.106104","DOIUrl":"10.1016/j.rvsc.2026.106104","url":null,"abstract":"<div><div>This study evaluated the effects of different litter systems—plastic-grid flooring, wood shavings, and zeolite-enriched shavings—on the behavioral, welfare, and physiological responses of broiler chickens. A total of 504 one-day-old Ross 308 male chicks were randomly assigned to three flooring treatments, each with four replicates of 42 birds. Housing conditions consisted of conventional wood-shavings litter, a raised plastic-grid flooring system, and a zeolite-supplemented wood-shavings mixture. At 42 days of age, welfare and physiological parameters were assessed in 120 birds (10 per replicate), including tonic immobility and heterophile-to-lymphocyte ratios. Zeolite-enriched litter resulted in significantly lower ambient ammonia concentrations (<em>P</em> &lt; 0.001). Behavioral observations revealed that broilers on plastic-grid floors performed less dust bathing but more stretching (<em>P</em> &lt; 0.001), whereas zeolite litter increased pecking activity, suggesting substrate-dependent modulation of comfort and exploratory behaviors. Significant differences were also found in footpad dermatitis (<em>P</em> = 0.001) and plumage cleanliness (<em>P</em> = 0.007). Plastic-grid flooring reduced podiatric lesions and improved hygiene but restricted natural behavior, while zeolite improved air quality but increased footpad damage. Neither tonic immobility nor heterophile-to-lymphocyte ratios differed significantly among groups, indicating comparable physiological stress levels. Overall, these results highlight that litter materials distinctly influence environmental hygiene, behavioral expression, and integumentary welfare. The findings underline the importance of developing flooring systems that balance hygienic advantages with behavioral and welfare needs to achieve optimal broiler welfare and productivity.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106104"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146213995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Staphylococcus haemolyticus isolated from the Elaphurus davidianus: Pathogenicity and antimicrobial susceptibility profile","authors":"Yongcheng Meng ,&nbsp;Qingyan Han ,&nbsp;Mengling Han ,&nbsp;Zhenpeng Li ,&nbsp;Jie Wang ,&nbsp;Sihan Zuo ,&nbsp;Zhen Huang ,&nbsp;Qian Mu ,&nbsp;Yongli Hua ,&nbsp;Wanling Yao ,&nbsp;Wangdong Zhang","doi":"10.1016/j.rvsc.2026.106116","DOIUrl":"10.1016/j.rvsc.2026.106116","url":null,"abstract":"<div><div><em>Staphylococcus haemolyticus</em> is an important zoonotic pathogen. The objective of this study was to investigate the pathogenicity of a <em>Staphylococcus haemolyticus</em> isolated from the blood of <em>Elaphurus davidianus</em> and evaluate its potential risks to public health. A combination of methods including 16S rRNA sequencing, PCR, antimicrobial susceptibility testing and mouse challenge assay was employed to systematically investigate its phylogenetic relationships, growth characteristics, virulence and antimicrobial resistance genes, LD₅₀, and antimicrobial resistance profile. The results indicated that the strain was identified as <em>Staphylococcus haemolyticus.</em> The LD₅₀ of the strain in mice was determined to be 6.4 × 10⁸ CFU/ml, and the strain caused significant pathological lesions in the heart, lung, spleen, kidney and liver of the mice. In addition, the strain harbored 8 virulence genes, including <em>Lipase</em>, <em>Polyglutamic acid capsule</em>, <em>Uge</em>, <em>WbtP</em>, <em>Thermonuclease</em>, <em>Type VII secretion system</em>, <em>Autolysin,</em> and <em>Cytolysin</em>. Meanwhile, it exhibited resistance to 18 antibiotics, such as oxacillin, ampicillin, benzylpenicillin, levofloxacin, ceftazidime, streptomycin, imipenem, minocycline, tetracycline, doxycycline, azithromycin, erythromycin, clindamycin, lincomycin, vancomycin, chloramphenicol, florfenicol, and cotrimoxazole, and harbored 12 antimicrobial resistance genes, including <em>msrA</em>, <em>mphC</em>, <em>PC1</em>, <em>AAC(6′)-Ie-APH(2″)-Ia, vanY</em> gene in <em>vanB</em> cluster, <em>vanY</em> gene in <em>vanM</em> cluster, <em>APH(3′)-IIIa, vanT</em> gene in <em>vanG</em> cluster, <em>sepA</em>, <em>norC</em>, <em>sdrM</em>, and <em>dfrG</em>. Collectively, these findings indicated that the strain possessed strong virulence and exhibited resistance to multiple antibiotics. This suggested that it posed considerable potential risks to public health. This study provides a scientific basis for further investigation into the pathogenic mechanisms, antimicrobial resistance mechanisms, and prevention and control strategies of this strain.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106116"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Veterinary perspectives on biosecurity measures in small-scale farming systems across European countries: Results from a cross-national survey","authors":"F. Duarte ,&nbsp;J. Prodanov-Radulović ,&nbsp;B. Mehmedi ,&nbsp;A. Piccirillo ,&nbsp;M. Stukelj ,&nbsp;E. Kldiashvili ,&nbsp;V. Nedosekov ,&nbsp;B. Milovanovic ,&nbsp;N.D. Ayaz ,&nbsp;R. Yildiz ,&nbsp;S. Meling ,&nbsp;I. Toftaker ,&nbsp;A. Sirbu ,&nbsp;A. Dodovski ,&nbsp;A. Allepuz ,&nbsp;A. Zbikowski ,&nbsp;Xh. Koleci ,&nbsp;C. Berger ,&nbsp;J. Starič ,&nbsp;M.E. Filippitzi ,&nbsp;I.M.G.A. Santman-Berends","doi":"10.1016/j.rvsc.2026.106089","DOIUrl":"10.1016/j.rvsc.2026.106089","url":null,"abstract":"<div><div>Maintaining sufficient levels of biosecurity at the farm level is crucial to prevent the introduction and spread of pathogens. However, data on biosecurity awareness and implementation in small-scale or backyard (hereafter referred to as small-scale) holdings across Europe are lacking. While the risk posed by these farms is generally regarded as limited, they represent a diverse group of farmers and do play a role in disease introduction and spread. The aim of this study was to explore veterinarians' perspectives on small-scale farming in Europe, including the frequency of farm visits, the definition of small-scale farming, the current status of biosecurity, and the most important measures to prevent pathogen introduction and spread. A multidisciplinary team developed a comprehensive survey to collect veterinarians' perspectives on biosecurity in small-scale farms. The survey was translated into 16 languages, digitalised, and distributed online between July and December 2024 by participants of COST Action BETTER. Data were analysed descriptively, and clusters of veterinarians were distinguished using multiple correspondence analysis. In total, 346 veterinarians from 23 countries participated in the survey. There is no standard definition of small-scale farming throughout Europe. According to the participating veterinarians, a small-scale farm was defined as having a median number of fewer than 20 cattle, 30 small ruminants, 13 pigs, or 99 heads of poultry. Three clusters of veterinarians were identified based on geographical location, field experience, biosecurity training, and perceived biosecurity awareness within the small-scale farming community. Biosecurity measures already applied in small-scale farming included fencing, carcass management, and biosecurity measures related to purchasing and feeding practices. According to the participating veterinarians, the most important biosecurity measures for small-scale farms to prevent pathogen introduction and spread included factors related to the introduction of animals, such as quarantine facilities, testing for health status, and purchasing animals from farms with a high health status. Besides factors related to the introduction of animals, hygiene measures and fencing were also frequently indicated as the most important biosecurity measures. Nevertheless, significant differences were found between the clusters regarding the importance of specific biosecurity measures. This study provides valuable insights into the perceived awareness, implementation, and desired biosecurity measures in European small-scale farming and underscores the importance of integrating small farms into “One Health” strategies, given their potential role in the spread of infectious diseases.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106089"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146119720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One health strategies for zoonosis prevention in developing countries: A systematic review (2015–2025)","authors":"Kunta Adnan Sahiman ,&nbsp;Siti Azizah ,&nbsp;Kuswati Kuswati ,&nbsp;Andi Moh. Iekram","doi":"10.1016/j.rvsc.2026.106091","DOIUrl":"10.1016/j.rvsc.2026.106091","url":null,"abstract":"<div><h3>Background</h3><div>Despite growing global investment in One Health initiatives, limited systematic synthesis exists examining veterinary authority strategies and their performance outcomes in developing countries, creating a knowledge gap for evidence-based policy formulation.</div></div><div><h3>Objective</h3><div>To develop a comprehensive taxonomy of One Health zoonosis prevention strategies implemented by veterinary authorities in developing countries and establish quantitative effectiveness patterns across resource-constrained settings.</div></div><div><h3>Methods</h3><div>We conducted a systematic review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines, searching Scopus, Web of Science, and PubMed for peer-reviewed studies published between January 2015 and July 2025. Two reviewers independently screened 126 records after deduplication with inter-rater agreement (κ = 0.82). We employed mixed-methods synthesis integrating thematic analysis and quantitative effectiveness scoring across 42 included studies.</div></div><div><h3>Results</h3><div>From 42 studies spanning 18 countries, we identified 14 distinct One Health strategies organized into three dominant modalities: intersectoral coordination mechanisms (35.7%), surveillance system enhancement (28.6%), and integrated service delivery (21.4%). Integrated approaches consistently demonstrated superior effectiveness scores (77–90, 95% CI: 73–94) compared to single-intervention strategies (25–95, 95% CI: 18–88). Mobile surveillance systems achieved 14-fold reporting increases (RR = 14.0, 95% CI: 13.8–14.2), while integrated surveillance systems demonstrated improved epidemiological understanding across human-animal interfaces.</div></div><div><h3>Conclusions</h3><div>Implementation quality and strategic integration represent more critical determinants of success than intervention type or resource intensity alone. Sub-optimal policy implementation and poor inter-sectoral coordination were consistently identified as barriers to achieving desired outcomes. These findings provide evidence-based guidance for optimizing limited resources in developing countries.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106091"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146132797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short communication: Amitraz treatments do not increase the frequency of mutations in the β2-adrenergic octopamine receptor in Varroa destructor: a field study in Central Spain","authors":"Antonio Pérez-Pérez ,&nbsp;Carolina Bartolomé ,&nbsp;Soledad Sagastume ,&nbsp;Aránzazu Meana ,&nbsp;Raquel Martín-Hernández ,&nbsp;Xulio Maside ,&nbsp;Mariano Higes","doi":"10.1016/j.rvsc.2026.106101","DOIUrl":"10.1016/j.rvsc.2026.106101","url":null,"abstract":"<div><div>The ectoparasitic mite <em>Varroa destructor</em> is a major threat to <em>Apis mellifera</em> colonies. Beekeepers use acaricides such as amitraz for control, but resistance has been reported, possibly linked to mutations in the <em>Octβ2R</em> gene. This study examined the frequency of these mutations in <em>Varroa</em> populations from two management systems: organic (oxalic acid treatment) and conventional (amitraz treatment). DNA was extracted individually from 83 mites collected from 14 apiaries, and a 1064 bp fragment of <em>Octβ2R</em> was amplified and sequenced. The F290L-related mutation appeared at a high frequency (89%), with no significant differences between treatments. No other reported mutations were found. The widespread homozygosity of F290L and lack of treatment-related variation suggest that this mutation existed before amitraz use, reflecting historical genetic variation rather than recent selection. Further research is needed to clarify its role in amitraz resistance.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106101"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146137767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Five-year evidence synthesis of African swine fever in domestic pigs in Southeast Asia: A systematic review and meta-analysis","authors":"Lintang Winantya Firdausy ,&nbsp;Faisal Fikri ,&nbsp;Salipudin Tasil Maslamama ,&nbsp;Muhammad Thohawi Elziyad Purnama","doi":"10.1016/j.rvsc.2026.106088","DOIUrl":"10.1016/j.rvsc.2026.106088","url":null,"abstract":"<div><div>African swine fever (ASF) continues to threaten pig production systems across Southeast Asia, yet regional epidemiological patterns remain fragmented. This systematic review and meta-analysis synthesized prevalence data to provide a consolidated assessment of ASF burden, spatial distribution, and temporal trends from 2019 to 2023. Following PRISMA 2020 guidelines, a comprehensive literature search was conducted across eight major databases and supplementary sources, with protocol registration in the Open Science Framework. Four reviewers independently screened studies, and eligible publications underwent quality appraisal using the Joanna Briggs Institute (JBI) checklist. Data extraction encompassed prevalence estimates, diagnostic methods, sample types, and geographic information, which were subsequently mapped using QGIS. Meta-analyses, subgroup analyses, meta-regression modelling, and Egger's test were performed in R Studio using the “meta” and “metafor” packages. Twelve studies met inclusion criteria, representing seven Southeast Asian countries. The random-effects model yielded an overall pooled prevalence of 29.14% (95% CI: 20.56–37.72), with substantial heterogeneity (<em>I</em>^<em>2</em> = 100%; <em>τ</em>^<em>2</em> = 0.1012). Subgroup analyses demonstrated marked variations by study period, diagnostic method, sample type, and country, with the highest prevalence estimates reported in Vietnam and Lao PDR. Meta-regression identified a significant decline in prevalence over time (<em>p</em> &lt; 0.001). Spatial mapping revealed pronounced regional burden prevalence, particularly in the Lao PDR and southern Vietnam. Funnel plot asymmetry and regression testing suggested the presence of small-study effects. These findings underscore the persistent and heterogenous nature of ASF across Southeast Asia, emphasizing the need for harmonized surveillance, strengthened biosecurity in smallholder systems, and enhanced diagnostic capacity.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106088"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146119674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of injection site on the pharmacokinetics of danofloxacin in Pekin ducks (Anas platyrhynchos domestica)","authors":"Kamil Uney ,&nbsp;Orhan Corum ,&nbsp;Duygu Durna Corum ,&nbsp;Devran Coskun ,&nbsp;Pedro Marin ,&nbsp;Mario Giorgi ,&nbsp;Amnart Poapolathep ,&nbsp;Saranya Poapolathep ,&nbsp;Tugce Karaahmetli ,&nbsp;Enver Yazar ,&nbsp;Muammer Elmas","doi":"10.1016/j.rvsc.2026.106122","DOIUrl":"10.1016/j.rvsc.2026.106122","url":null,"abstract":"<div><div>The purpose of this study was to investigate the influence of injection site on danofloxacin pharmacokinetics in Pekin ducks. Thirty-two male Peking ducks were divided into 4 equal groups as intravenous (IV), pectoral muscles (IMP), thigh muscles (IMT) and subcutaneous (SC). Danofloxacin was administered to all groups at a dose of 10 mg/kg. Plasma concentrations of danofloxacin were quantified by HPLC-UV. The volume of distribution at steady state and total clearance values of danofloxacin after IV injections in ducks were 4.43 L/kg and 0.42 L/h/kg, respectively. The terminal elimination half-life (t_1/2ʎz), area under the concentration-versus time curve (AUC)_0-last, and peak plasma concentration (C_max) were similar after SC and IMP injections of danofloxacin. However, t_1/2ʎz was shorter and AUC_0-last and C_max were lower in the IMT group compared to the IMP group. The bioavailability was lower in the IMT group than in the IMP and SC groups. Danofloxacin exhibited similar pharmacokinetic profiles after SC and IMP injection into Pekin ducks. In the IMT group, pharmacokinetics altered significantly, resulting in reduced body exposure and residence time of danofloxacin. Optimizing the injection site to subcutaneous or pectoral muscle routes may improve danofloxacin's therapeutic efficacy in Pekin ducks, while caution should be applied with thigh muscle injections due to reduced bioavailability and systemic exposure.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106122"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147309596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in expression of growth, immune activity and adaptation related genes in heat stressed dorper and second cross lambs","authors":"Aleena Joy ,&nbsp;Swagat Mohapatra ,&nbsp;Frank R. Dunshea ,&nbsp;Brian J. Leury ,&nbsp;Kristy DiGiacomo ,&nbsp;Minghao H. Zhang ,&nbsp;Archana Abhijith ,&nbsp;Richard Osei- Amponsah ,&nbsp;Iain J. Clarke ,&nbsp;Surinder Singh Chauhan","doi":"10.1016/j.rvsc.2026.106087","DOIUrl":"10.1016/j.rvsc.2026.106087","url":null,"abstract":"","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"203 ","pages":"Article 106087"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146081420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}