Jiwon Yang, Jihyeon Song, Su Ji Kim, Gayeon You, Jun Bae Lee, Hyejung Mok
{"title":"Chronic infrared‐A irradiation‐induced photoaging of human dermal fibroblasts from different donors at physiological temperature","authors":"Jiwon Yang, Jihyeon Song, Su Ji Kim, Gayeon You, Jun Bae Lee, Hyejung Mok","doi":"10.1111/phpp.12793","DOIUrl":"https://doi.org/10.1111/phpp.12793","url":null,"abstract":"In this study, we examined cellular responses to acute and chronic IRA irradiation at mild and natural levels of exposure in two types of human fibroblasts, each isolated from a different donor, at physiological temperature (34°C).","PeriodicalId":20060,"journal":{"name":"Photodermatology","volume":"115 1","pages":"571 - 581"},"PeriodicalIF":0.0,"publicationDate":"2022-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76842654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Lodi, M. Sannino, G. Cannarozzo, L. Bennardo, S. Nisticò
{"title":"Non‐epidermolytic palmoplantar keratoderma treated with blue LED light","authors":"G. Lodi, M. Sannino, G. Cannarozzo, L. Bennardo, S. Nisticò","doi":"10.1111/phpp.12791","DOIUrl":"https://doi.org/10.1111/phpp.12791","url":null,"abstract":"ulated at the mitochondrial level through the action of cytochrome oxidase. 5 Cytochrome oxidase is the terminal enzyme of the respi ratory chain that allows the transfer of electrons from cytochrome c to oxygen molecules, and that activates the production of super oxide anion that stimulates ATP (adenosine triphosphate) synthe -sis. Photobiomodulation has been clinically reported to positively impact on many dermatological conditions and on hair growth. 6 We decided nm studies demonstrated that keratinocyte proliferation is and differentiation of pri mary be ulation are This case report shows clinically significant re sults that could be used to start a prospective study on PPK treatment. Further studies may be in order to confirm the effectiveness and safety of biostimulation with visible blue light in PPK.","PeriodicalId":20060,"journal":{"name":"Photodermatology","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72731952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Eid, R. Aly, Shaimaa Abd Elkarim Elkholy, O. Sorour
{"title":"Influence of narrow‐band ultraviolet B therapy on sirtuin 1 expression in lesional skin of patients with chronic plaque psoriasis: Relation to clinical improvement and interferon‐γ expression","authors":"A. Eid, R. Aly, Shaimaa Abd Elkarim Elkholy, O. Sorour","doi":"10.1111/phpp.12790","DOIUrl":"https://doi.org/10.1111/phpp.12790","url":null,"abstract":"Reduced sirtuin 1 (Sirt1) expression in psoriasis was previously reported, and its activation was associated with disease improvement. Narrow‐band ultraviolet B (NB‐UVB) downregulates several pro‐inflammatory cytokines such as interferon‐γ (IFN‐γ) and influences keratinocyte differentiation in psoriasis.","PeriodicalId":20060,"journal":{"name":"Photodermatology","volume":"43 1","pages":"555 - 563"},"PeriodicalIF":0.0,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89801831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. B. Abdel-Naser, H. Seltmann, A. Altenburg, C. Zouboulis
{"title":"Endothelins and α‐melanocyte‐stimulating hormone are increased in plasma of patients treated with UVA1 and psoralen plus UVA","authors":"M. B. Abdel-Naser, H. Seltmann, A. Altenburg, C. Zouboulis","doi":"10.1111/phpp.12789","DOIUrl":"https://doi.org/10.1111/phpp.12789","url":null,"abstract":"Ultraviolet light (UV) and/or UVA plus psoralen (PUVA) may have a systemic effect on melanocytes of shielded skin. Melanocyte pro liferation and occurrence of UV- induced lentigines and malignan cies in sun- protected skin are in favor of this concept. 1– 4 Release of several melanocyte mitogens might be responsible for this ef -fect, but up- to- date results are inconsistent. In PUVA- treated re pigmenting generalized (non- segmental) vitiligo patients, a study has shown increased endothelin (ET)- 1 in plasma, whereas another study revealed normal ET- 1 but increased basic fibroblast growth factor (bFGF), stem cell factor (SCF) and hepatocyte growth factor (HGF) in sera. 5,6 In the present study, plasma ET- 1- 3, α - melanocyte-stimulating hormone ( α - MSH), bFGF, SCF, HGF, and granulocyte-macrophage colony- stimulating factor (GM- CSF) were assessed in the plasma of patients treated with UVA1 ( n = 16; disseminated morphea n = 4, eczema n = 6, lichen sclerosus et atrophicus n = 2, disseminated granuloma annulare n = 4), and cream PUVA ( n = 16; mycosis fungoides n = 3, prurigo simplex n = 3, atopic dermatitis n = 4, and non- segmental vitiligo n = 6). Selected patients were eligi ble for total body irradiation, were of similar age, day 1 but not at day 14 indicating that ET and α - MSH elevation is sustained and remains high so long as patients are under treat ment. Expectedly and due to the presence of the photosensitizer psoralen, PUVA therapy was significantly more effective in ET and α - MSH release in comparison with UVA1 at all post- irradiation eval uation time points.","PeriodicalId":20060,"journal":{"name":"Photodermatology","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85211772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Ju, R. W. Lee, Sujin Park, J. Bae, S. Oh, Jeonghyun Shin, H. Kang
{"title":"Maintenance phototherapy for vitiligo: A multicenter, randomized controlled trial","authors":"H. Ju, R. W. Lee, Sujin Park, J. Bae, S. Oh, Jeonghyun Shin, H. Kang","doi":"10.1111/phpp.12784","DOIUrl":"https://doi.org/10.1111/phpp.12784","url":null,"abstract":"included both NBUVB- and EL- treated patients, although the latter group tended to have localized lesions. In ad -dition, a one- month interval could have been too long to prevent re- activation of skin autoimmunity. However, the combination of TCI and phototherapy as maintenance may be synergistic as TCI has shown a promising result. Further studies should be investigated with larger sample sizes at more regular intervals to ensure the effi cacy of maintenance phototherapy.","PeriodicalId":20060,"journal":{"name":"Photodermatology","volume":"21 1","pages":"608 - 610"},"PeriodicalIF":0.0,"publicationDate":"2022-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73250798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In Memoriam","authors":"Elisabeth G. Richard, H. Lim","doi":"10.1111/phpp.12550","DOIUrl":"https://doi.org/10.1111/phpp.12550","url":null,"abstract":"","PeriodicalId":20060,"journal":{"name":"Photodermatology","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87116217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Park, Uri Shon, G. Seong, M. Kim, B. Park, S. Hong
{"title":"A comparative clinical trial to evaluate efficacy and safety of the 308‐nm excimer laser and the gain‐switched 311‐nm titanium:sapphire laser in the treatment of vitiligo","authors":"M. Park, Uri Shon, G. Seong, M. Kim, B. Park, S. Hong","doi":"10.1111/phpp.12512","DOIUrl":"https://doi.org/10.1111/phpp.12512","url":null,"abstract":"Ultraviolet B (UVB) laser irradiation in a targeted manner is a reasonable treatment option for localized vitiligo. Recently, narrow‐band UVB gain‐switched 311‐nm titanium:sapphire lasers (TSL) were developed for the treatment of localized vitiligo. We aimed to compare efficacy, patient satisfaction, and safety between the conventional 308‐nm excimer laser (EL) and gain‐switched 311‐nm TSL in patients with vitiligo.","PeriodicalId":20060,"journal":{"name":"Photodermatology","volume":"17 1","pages":"104 - 97"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91008884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yan Li, Chun-Yan Yang, M. Man, Hua Gu, Wenjuan Wu, Ying Tu, Dong-Mei Ding, Li He
{"title":"Disruption of epidermal permeability barrier enhances UV‐induced hyperpigmentation","authors":"Yan Li, Chun-Yan Yang, M. Man, Hua Gu, Wenjuan Wu, Ying Tu, Dong-Mei Ding, Li He","doi":"10.1111/phpp.12515","DOIUrl":"https://doi.org/10.1111/phpp.12515","url":null,"abstract":"The epidermal permeability barrier not only prevents transcutaneous loss of water and nutrients, but also protects the body from the outside insults (1, 2). Prior studies have demonstrated that permeability barrier dysfunction favors cutaneous colonization of Staphylococcus aureus (3). Moreover, disruption of epidermal permeability barrier increases transcutaneous absorption of topical substances (4). Likewise, a defective epidermal permeability barrier also decreases erythema threshold to UVB radiation.","PeriodicalId":20060,"journal":{"name":"Photodermatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89263104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Chasseuil, D. Boutin, E. Frouin, A. Leblanc, E. Hainaut
{"title":"Photodistributed sarcoidosis with ophthalmic, arterial and pulmonary symptoms","authors":"H. Chasseuil, D. Boutin, E. Frouin, A. Leblanc, E. Hainaut","doi":"10.1111/phpp.12513","DOIUrl":"https://doi.org/10.1111/phpp.12513","url":null,"abstract":"The photo-induced variant of sarcoidosis is rare. To our knowledge, nine cases have been described.1-6 Symptoms generally consist of mildly erythematous papules on the face and upper chest that respond to topical or systemic corticosteroids and antimalarial agents. We report a case of severe eruptive, photo-induced sarcoidosis with ophthalmic, pulmonary and femoral artery involvement treated successfully with methotrexate.","PeriodicalId":20060,"journal":{"name":"Photodermatology","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79074632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Hellen, E. Nic Dhonncha, A. Havelin, L. Fleming, A. Kavanagh, A. Lally, B. Kirby, B. Moriarty, P. Collins
{"title":"An audit of pain scores with conventional and white light topical 5‐methyl aminolaevulinic acid photodynamic therapy for superficial basal cell carcinoma and squamous cell carcinoma in situ","authors":"R. Hellen, E. Nic Dhonncha, A. Havelin, L. Fleming, A. Kavanagh, A. Lally, B. Kirby, B. Moriarty, P. Collins","doi":"10.1111/phpp.12521","DOIUrl":"https://doi.org/10.1111/phpp.12521","url":null,"abstract":"Conventional PDT (c-PDT) is an effective treatment for diffuse actinic keratoses, superficial basal cell carcinoma (sBCC) and squamous cell carcinoma in situ (SCCis). The prodrug (5-methyl aminolaevulinic acid, MAL) is applied to the treatment area for three hours before exposure to 50 J/cm2 red light (615-645 nm) at 50 mW/cm2 from light emitting diode (LED) lamps (Aktilite CL128 and Omnilux PDT). Patients receive two treatments one week apart. The main drawback is pain. Various approaches have been investigated to reduce pain scores in PDT, including alternative light sources and protocols.","PeriodicalId":20060,"journal":{"name":"Photodermatology","volume":"92 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78675636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}