R. Hellen, E. Nic Dhonncha, A. Havelin, L. Fleming, A. Kavanagh, A. Lally, B. Kirby, B. Moriarty, P. Collins
{"title":"对浅表性基底细胞癌和鳞状细胞癌进行常规和白光局部5‐甲基氨基乙酰丙酸光动力治疗的疼痛评分审计","authors":"R. Hellen, E. Nic Dhonncha, A. Havelin, L. Fleming, A. Kavanagh, A. Lally, B. Kirby, B. Moriarty, P. Collins","doi":"10.1111/phpp.12521","DOIUrl":null,"url":null,"abstract":"Conventional PDT (c-PDT) is an effective treatment for diffuse actinic keratoses, superficial basal cell carcinoma (sBCC) and squamous cell carcinoma in situ (SCCis). The prodrug (5-methyl aminolaevulinic acid, MAL) is applied to the treatment area for three hours before exposure to 50 J/cm2 red light (615-645 nm) at 50 mW/cm2 from light emitting diode (LED) lamps (Aktilite CL128 and Omnilux PDT). Patients receive two treatments one week apart. The main drawback is pain. Various approaches have been investigated to reduce pain scores in PDT, including alternative light sources and protocols.","PeriodicalId":20060,"journal":{"name":"Photodermatology","volume":"92 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"An audit of pain scores with conventional and white light topical 5‐methyl aminolaevulinic acid photodynamic therapy for superficial basal cell carcinoma and squamous cell carcinoma in situ\",\"authors\":\"R. Hellen, E. Nic Dhonncha, A. Havelin, L. Fleming, A. Kavanagh, A. Lally, B. Kirby, B. Moriarty, P. Collins\",\"doi\":\"10.1111/phpp.12521\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Conventional PDT (c-PDT) is an effective treatment for diffuse actinic keratoses, superficial basal cell carcinoma (sBCC) and squamous cell carcinoma in situ (SCCis). The prodrug (5-methyl aminolaevulinic acid, MAL) is applied to the treatment area for three hours before exposure to 50 J/cm2 red light (615-645 nm) at 50 mW/cm2 from light emitting diode (LED) lamps (Aktilite CL128 and Omnilux PDT). Patients receive two treatments one week apart. The main drawback is pain. Various approaches have been investigated to reduce pain scores in PDT, including alternative light sources and protocols.\",\"PeriodicalId\":20060,\"journal\":{\"name\":\"Photodermatology\",\"volume\":\"92 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Photodermatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1111/phpp.12521\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Photodermatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/phpp.12521","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
An audit of pain scores with conventional and white light topical 5‐methyl aminolaevulinic acid photodynamic therapy for superficial basal cell carcinoma and squamous cell carcinoma in situ
Conventional PDT (c-PDT) is an effective treatment for diffuse actinic keratoses, superficial basal cell carcinoma (sBCC) and squamous cell carcinoma in situ (SCCis). The prodrug (5-methyl aminolaevulinic acid, MAL) is applied to the treatment area for three hours before exposure to 50 J/cm2 red light (615-645 nm) at 50 mW/cm2 from light emitting diode (LED) lamps (Aktilite CL128 and Omnilux PDT). Patients receive two treatments one week apart. The main drawback is pain. Various approaches have been investigated to reduce pain scores in PDT, including alternative light sources and protocols.
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