Non‐epidermolytic palmoplantar keratoderma treated with blue LED light

ulated at the mitochondrial level through the action of cytochrome oxidase. 5 Cytochrome oxidase is the terminal enzyme of the respi ratory chain that allows the transfer of electrons from cytochrome c to oxygen molecules, and that activates the production of super oxide anion that stimulates ATP (adenosine triphosphate) synthe -sis. Photobiomodulation has been clinically reported to positively impact on many dermatological conditions and on hair growth. 6 We decided nm studies demonstrated that keratinocyte proliferation is and differentiation of pri mary be ulation are This case report shows clinically significant re sults that could be used to start a prospective study on PPK treatment. Further studies may be in order to confirm the effectiveness and safety of biostimulation with visible blue light in PPK.