Non‐epidermolytic palmoplantar keratoderma treated with blue LED light

G. Lodi, M. Sannino, G. Cannarozzo, L. Bennardo, S. Nisticò
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Abstract

ulated at the mitochondrial level through the action of cytochrome oxidase. 5 Cytochrome oxidase is the terminal enzyme of the respi ratory chain that allows the transfer of electrons from cytochrome c to oxygen molecules, and that activates the production of super oxide anion that stimulates ATP (adenosine triphosphate) synthe -sis. Photobiomodulation has been clinically reported to positively impact on many dermatological conditions and on hair growth. 6 We decided nm studies demonstrated that keratinocyte proliferation is and differentiation of pri mary be ulation are This case report shows clinically significant re sults that could be used to start a prospective study on PPK treatment. Further studies may be in order to confirm the effectiveness and safety of biostimulation with visible blue light in PPK.
蓝光LED灯治疗非表皮松解性掌足底角化病
在线粒体水平上通过细胞色素氧化酶的作用进行调节。细胞色素氧化酶是呼吸链的末端酶,它允许电子从细胞色素c转移到氧分子,并激活产生刺激ATP(三磷酸腺苷)合成的超氧阴离子。据临床报道,光生物调节对许多皮肤病和头发生长有积极的影响。我们认为,纳米研究表明,角质细胞增殖和细胞分化是有效的,该病例报告显示了具有临床意义的结果,可用于启动PPK治疗的前瞻性研究。进一步的研究可能是为了确认可见蓝光生物刺激对PPK的有效性和安全性。
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