A. Eid, R. Aly, Shaimaa Abd Elkarim Elkholy, O. Sorour
{"title":"窄带紫外线B治疗对慢性斑块型银屑病患者病变皮肤sirtuin 1表达的影响:与临床改善和干扰素γ表达的关系","authors":"A. Eid, R. Aly, Shaimaa Abd Elkarim Elkholy, O. Sorour","doi":"10.1111/phpp.12790","DOIUrl":null,"url":null,"abstract":"Reduced sirtuin 1 (Sirt1) expression in psoriasis was previously reported, and its activation was associated with disease improvement. Narrow‐band ultraviolet B (NB‐UVB) downregulates several pro‐inflammatory cytokines such as interferon‐γ (IFN‐γ) and influences keratinocyte differentiation in psoriasis.","PeriodicalId":20060,"journal":{"name":"Photodermatology","volume":"43 1","pages":"555 - 563"},"PeriodicalIF":0.0000,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Influence of narrow‐band ultraviolet B therapy on sirtuin 1 expression in lesional skin of patients with chronic plaque psoriasis: Relation to clinical improvement and interferon‐γ expression\",\"authors\":\"A. Eid, R. Aly, Shaimaa Abd Elkarim Elkholy, O. Sorour\",\"doi\":\"10.1111/phpp.12790\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Reduced sirtuin 1 (Sirt1) expression in psoriasis was previously reported, and its activation was associated with disease improvement. Narrow‐band ultraviolet B (NB‐UVB) downregulates several pro‐inflammatory cytokines such as interferon‐γ (IFN‐γ) and influences keratinocyte differentiation in psoriasis.\",\"PeriodicalId\":20060,\"journal\":{\"name\":\"Photodermatology\",\"volume\":\"43 1\",\"pages\":\"555 - 563\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-03-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Photodermatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1111/phpp.12790\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Photodermatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/phpp.12790","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Influence of narrow‐band ultraviolet B therapy on sirtuin 1 expression in lesional skin of patients with chronic plaque psoriasis: Relation to clinical improvement and interferon‐γ expression
Reduced sirtuin 1 (Sirt1) expression in psoriasis was previously reported, and its activation was associated with disease improvement. Narrow‐band ultraviolet B (NB‐UVB) downregulates several pro‐inflammatory cytokines such as interferon‐γ (IFN‐γ) and influences keratinocyte differentiation in psoriasis.
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