Oman Journal of Ophthalmology最新文献_第4页

Vitreous hemorrhage after weight loss therapy. 减肥治疗后玻璃体出血。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_60_26

Ahmed S Al-Hinai

引用次数: 0

Pharmacological management of nystagmus: An in-depth review for clinical practice. 眼球震颤的药物治疗：临床实践的深入回顾。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_246_25

Hassan Asadigandomani, Paria Kazemian, Masoud Khorrami-Nejad, Humaid Sulaiman Al Kalbani, Babak Masoomian

{"title":"Pharmacological management of nystagmus: An in-depth review for clinical practice.","authors":"Hassan Asadigandomani, Paria Kazemian, Masoud Khorrami-Nejad, Humaid Sulaiman Al Kalbani, Babak Masoomian","doi":"10.4103/ojo.ojo_246_25","DOIUrl":"10.4103/ojo.ojo_246_25","url":null,"abstract":"Nystagmus, characterized by involuntary ocular movements, presents significant challenges in both congenital and acquired forms, often significantly impacting visual acuity and quality of life. This comprehensive review examines the current landscape of pharmacological interventions for nystagmus, highlighting several key drug classes and their mechanisms of action. To identify relevant studies, an extensive literature search was conducted in PubMed, Web of Science, and Scopus, covering English-language articles from 1960 to 2025. Gabapentin, a calcium channel blocker with potential effects on gamma-aminobutyric acid (GABA) activity, and baclofen, a GABAergic agent, have shown promise in treating both congenital and acquired forms, whereas glutamate antagonists like memantine have demonstrated efficacy in some cases. Potassium channel blockers, including aminopyridines, have proven especially effective for certain acquired nystagmus types, particularly downbeat nystagmus. The potential of anticholinergic drugs and benzodiazepines in specific nystagmus subtypes is also discussed. Efficacy often varies among individuals, highlighting the need for personalized approaches. This review underscores the importance of both nystagmus reduction and preservation of normal eye movements. Although many medications show promise, most studies have small sample sizes and lack long-term data, making direct comparisons challenging. Therefore, further research (particularly large-scale randomized controlled trials) is needed to support the development of novel targeted therapies, including combination treatments or adjunctive nonpharmacological approaches, to improve management of this complex condition.","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 1","pages":"9-16"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13043125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cyclosporine A as an adjuvant therapy in high-risk penetrating keratoplasty: A systematic review and meta-analysis. 环孢素A作为高风险穿透性角膜移植术的辅助治疗：系统回顾和荟萃分析。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_288_24

Tania Tandra, Clarissa Djarizal, Syska Widyawati, Yulia Aziza

{"title":"Cyclosporine A as an adjuvant therapy in high-risk penetrating keratoplasty: A systematic review and meta-analysis.","authors":"Tania Tandra, Clarissa Djarizal, Syska Widyawati, Yulia Aziza","doi":"10.4103/ojo.ojo_288_24","DOIUrl":"10.4103/ojo.ojo_288_24","url":null,"abstract":"Immunologic rejection is a significant cause of graft failure in high-risk keratoplasty, with rejection rates exceeding 70% without immunosuppressive therapy. Cyclosporine A (CsA) is emerging as a valuable adjunct to corticosteroids, the standard rejection prevention therapy. A literature review conducted in March 2024 through PubMed, Proquest, and Google Scholar utilized keywords (keratoplasty OR \"high risk keratoplasty\" OR \"high risk corneal transplantation\" OR \"corneal transplantation\") AND (cyclosporine OR ciclosporin OR ciclosporine), covering studies from 2000 to 2024. The review included three randomized controlled trials, four retrospective cohort studies, and one retrospective case-control study, evaluating rejection-free graft survival rates and side effects associated with CsA therapy. Topical CsA significantly reduced rejection events compared to controls at 1 year follow-up (n = 215, 17.78% vs. 32.41%, risk ratios [RR] 0.55, 95% confidence interval [CI]: 0.34-0.92, P = 0.02, I 2 = 31%, fixed effects), whereas systemic CsA showed no significant difference (n = 248, 19.33% vs. 24.81%, RR 0.66, 95% CI: 0.40-1.08, P = 0.10, I 2 = 0%, fixed effects). No significant difference in graft survival rates was observed between the CsA and control groups. Systemic CsA was associated with systemic side effects, whereas topical CsA primarily caused ocular side effects. In summary, topical CsA significantly reduces rejection rates without substantial ocular or systemic side effects.","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 1","pages":"28-36"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13043114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Large language models and eye education: A narrative review. 大语言模型与眼教育：述评。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_223_24

Albert Andrew, Sasha Rodenko

引用次数: 0

The skills and keystone assessment for regional anesthesia (SanKARA) scoring system for evaluating competency in peribulbar anesthesia. 区域麻醉（SanKARA）评分系统评估球周麻醉能力的技巧和重点评估。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_129_25

Matteo Ripa, Deergha Pareek, Neeraj Apoorva Shah

{"title":"The skills and keystone assessment for regional anesthesia (SanKARA) scoring system for evaluating competency in peribulbar anesthesia.","authors":"Matteo Ripa, Deergha Pareek, Neeraj Apoorva Shah","doi":"10.4103/ojo.ojo_129_25","DOIUrl":"10.4103/ojo.ojo_129_25","url":null,"abstract":"Purpose: The purpose of this study was to introduce a standardized tool, developed through expert consensus with face and content validation, that integrates a comprehensive rubric with a scoring system for evaluating the ophthalmology residents' competency in peribulbar anesthesia: The Skills and Keystone Assessment for Regional Anesthesia (SanKARA) Scoring System.Materials and methods: A multidisciplinary expert panel from Sankara Eye Hospital, Jaipur, India, each with experience of ≥2000 peribulbar anesthesia blocks, was established to develop a tool that combined a comprehensive rubric outlining essential competency criteria with a scoring system designed to assign numerical values to performance. The explicit behavioral descriptors for each crucial step of the peribulbar block were scored using a modified four-point Dreyfus scale of skill acquisition.Results: The SanKARA Scoring System encompassed 20 crucial steps for evaluating competency in peribulbar anesthesia. These steps were further subgrouped into specific categories (pre-procedural-related, procedural-related, and post-procedural-related) to summarize the specific stages of the whole procedure. Key procedural aspects included needle positioning, drug administration, patient monitoring, and adverse event management.Conclusions: The SanKARA Scoring System integrates a structured rubric and scoring system to standardize peribulbar anesthesia training. This system can be globally adopted to assess and improve the training of ophthalmology residents, guide them in learning this paramount skill, and set a global competency benchmark.","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 1","pages":"65-74"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13043115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on of "Effect of ginkgo biloba extracts in the prevention of posterior capsule opacification after cataract surgery: A randomized clinical trial". 《银杏叶提取物预防白内障术后后囊膜混浊的随机临床试验》一文评论。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_295_25

Pugazhenthan Thangaraju, T Tamilselvan, T Y Sree Sudha, T Eswaran

引用次数: 0

Effect of Ginkgo biloba extracts in the prevention of posterior capsule opacification after cataract surgery: A randomized clinical trial - Response to reviewer comments. 银杏叶提取物预防白内障术后后囊膜混浊的作用：一项随机临床试验-对审稿人评论的回应。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_417_25

Amir Ahmadzadeh Amiri, Ali Ahmadzadeh Amiri, Hossein Asgari Rad, Fatemeh Daneshvar, Jamshid Yazdani Charati, Ahmad Ahmadzadeh Amiri

引用次数: 0

A stone in the orbit: Dramatic pediatric ocular trauma. 眼窝结石：戏剧性的儿童眼外伤。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_175_24

Meryem Benchekroun Belabbes, Narjisse Taouri, Imane Ed-Derraz, Lalla Ouafa Cherkaoui

引用次数: 0

Sighting dominance, retinal nerve fiber layer and macula; are they related? - An ocular dominance analysis study. 视优势、视网膜神经纤维层及黄斑；他们有亲戚关系吗？-眼优势分析研究。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_145_24

Roshni Robert, Mahesh Babu, Krishnendu Unnikannan, Konatham Shruthi

{"title":"Sighting dominance, retinal nerve fiber layer and macula; are they related? - An ocular dominance analysis study.","authors":"Roshni Robert, Mahesh Babu, Krishnendu Unnikannan, Konatham Shruthi","doi":"10.4103/ojo.ojo_145_24","DOIUrl":"10.4103/ojo.ojo_145_24","url":null,"abstract":"Purpose: The purpose of this study was to study ocular dominance and its association with retinal nerve fiber layer (RNFL) and macular thickness.Methodology: A cross-sectional study was conducted on 432 participants with nonpathological eyes. We determined the ocular dominance by the hole-in-card test (Dolman method). A comprehensive eye examination was conducted on the participants, including best-corrected visual acuity, intraocular pressure, and anterior and posterior segment examination. The RNFL thickness was measured using optical coherence tomography. The findings were analyzed using paired t-tests to compare between dominant and nondominant eyes.Results: Out of the 432 participants, 70.4% (304) showed right eye dominance of study population had right eye dominance. The average RNFL (AvRNFL) thickness showed a small but significantly higher value in dominant eyes compared to nondominant eyes. We found significantly higher RNFL thickness in temporal, inferior and nasal quadrants in dominant eyes compared to nondominant eyes. Age had minimal effect on the difference in AvRNFL thickness between dominant and nondominant eyes (P = 0.144). There was no significant difference in macular retinal thickness between the eyes.Conclusions: Ocular dominance was found predominantly in the right eye. The dominant eye showed greater AvRNFL thickness compared to nondominant eye. AvRNFL, inferior RNFL, Nasal RNFL, Temporal RNFL thickness were greater in the dominant eye compared to the nondominant eye. There was no difference in macular thickness. Our findings suggest the need to consider dominance in various disease entities, in clinical decision making and normative data particularly concerning retinal nerve fiber layer.","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 1","pages":"54-58"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13043111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147608948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydroxychloroquine retinopathy screening: An evidence-based national guideline. 羟氯喹视网膜病变筛查：循证国家指南。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_20_26

Rashmi Mercy Lobo, Washoo Mal, Ahmed Rashid Al-Hinai, Nawal Ali Al-Fadhil, Mohamed Said Al-Abri

引用次数: 0