Oman Journal of Ophthalmology最新文献

{"title":"A comparative study of retinal vein occlusion and serum 25 hydroxy Vitamin D at a tertiary care centre.","authors":"Aishwarya Bhattacharya, Swati Majumdar, Manali Sinha Ray, Debasmita Nandi, Sambuddha Ghosh, Debolina Banerjee","doi":"10.4103/ojo.ojo_364_24","DOIUrl":"10.4103/ojo.ojo_364_24","url":null,"abstract":"<p><strong>Background: </strong>Prevalence of retinal vascular occlusion is second to diabetic retinopathy and age-related macular degeneration. Various age-related local and systemic factors have been associated with retinal vein occlusion (RVO). Hemodynamic changes (venous stasis), degenerative changes of the vessel wall and blood hypercoagulability underlies the pathogenesis. The role of Vitamin D in modulating the inflammatory responses within the arterial wall, the capacity to attenuate the oxidative stress and direct effect of hypovitaminosis D on increased vascular resistance hints at a potential association of Vitamin D levels with disorders of retinal vasculature.</p><p><strong>Aim: </strong>To estimate serum 25-hydroxyvitamin D (25 OH Vit D) level in patients of RVO and compare it with matched controls.</p><p><strong>Materials and methods: </strong>Fifty patients of RVO as cases and 50 without RVO as controls underwent systemic and ocular examination including the estimation of serum 25 OH Vit D and other biochemical parameters.</p><p><strong>Statistical analysis: </strong>Statistical Package for the Social Sciences (SPSS) software version 25 was used for the analysis. An alpha level of 5% was taken, that is <i>P</i> < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>Mean serum 25 OH Vit D level in cases of RVO was 21.82 nanogram/deciliters (ng/dL) compared to 30.71 ng/dL in the control group which was significantly lower in cases compared to control (<i>P</i> < 0.001). The odds ratio calculated for RVO cases versus controls was 1.137; 95% confidence interval (1.074-1.203).</p><p><strong>Conclusion: </strong>A positive association of low serum 25 OH Vit D levels and RVO was found highlighting the importance of evaluating serum Vitamin D levels in all the cases of RVO. This correlation may have possible implications for prophylaxis and treatment of RVO, even though this part of our country gets abundant sunlight throughout the year.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"182-186"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resolution of the hole-related subclinical retinal detachment following barrage and sectorial laser photocoagulation in ischemic branch retinal vein occlusion.","authors":"Mustafa Kayabasi, Seher Köksaldi, Ali Osman Saatci","doi":"10.4103/ojo.ojo_148_23","DOIUrl":"10.4103/ojo.ojo_148_23","url":null,"abstract":"","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"243-245"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258823/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare case of precursor B-cell lymphoblastic lymphoma of the orbit in a child.","authors":"Ruhi Girish Jange, Kirthi Koka, Subramanian Krishnakumar, Dhaarani Jayaraman, Julius Xavier Scott, Bipasha Mukherjee","doi":"10.4103/ojo.ojo_346_24","DOIUrl":"10.4103/ojo.ojo_346_24","url":null,"abstract":"<p><p>A 5-year-old boy presented with gradually progressive painful proptosis of the left eye for 5 months. He had an incidental testicular swelling for which he underwent high inguinal orchidectomy and histopathology showed atypical lymphoid cells. His vision was 6/6, N6 in the right eye, and no perception of light in the left eye. Left eye examination revealed an inferior dystopia and total ophthalmoplegia with corneal exposure changes. A computerized tomography scan showed an isodense mass molding around the globe. An incision biopsy from the subconjunctival mass showed atypical large lymphocytes on histopathology which on immunohistochemistry confirmed a diagnosis of precursor B-cell lymphoblastic lymphoma (B-LBL). Bone marrow aspiration and biopsy were normal. The patient was started on oral steroids and high-risk acute LBL chemotherapy protocol to which he showed excellent response. Precursor B-LBL is a rare neoplasm of the pediatric and adolescent age group. A total of 22 cases involving the orbit have been reported to date of which 17 belonged to the pediatric age group. Early detection and prompt initiation of multiagent chemotherapy have shown good survival rates in these patients.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"212-215"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ocular perfusion in primary angle-closure suspect and primary angle-closure eyes without prior acute angle closure.","authors":"Reni Philip, Venkateshwaran Kannan, Lingam Vijaya, Rashima Asokan, Shantha Balekudaru, Annadurai Parivadhini, Ronnie George","doi":"10.4103/ojo.ojo_154_24","DOIUrl":"10.4103/ojo.ojo_154_24","url":null,"abstract":"<p><strong>Background: </strong>Acute intraocular pressure (IOP) spike in acute primary angle closure (APAC) decreases ocular blood flow. It is not known if this is true in primary angle-closure (PAC) eyes without prior APAC who may have had subacute attacks. Hence, we aimed to assess the ocular perfusion using optical coherence tomography angiography (OCTA) characteristics in normal, PAC suspect (PACS), and PAC eyes without APAC.</p><p><strong>Materials and methods: </strong>This was a prospective cross-sectional study, which determined patients' (40-80 years) optic nerve peripapillary perfusion, flux, and macular vessel density (6 mm × 6 mm and 3 mm × 3 mm) in the superficial retinal layer on OCTA.</p><p><strong>Results: </strong>We included 135 eyes of 135 patients (45 per subgroup). The mean age was 59.7 ± 8.3 years. The mean peripapillary perfusion was 44.4% ±1.5% in normal, 44.2% ±1.7% in PACS, and 44.1% ±1.5% in PAC eyes. There was no significant difference between OCTA parameters among normal, PACS, and PAC eyes (<i>P</i> = 0.75 - peripapillary perfusion, 0.92 - flux, 0.58 - 6 × 6 and 0.09 - 3 mm × 3 mm). The maximum recorded IOP was significantly correlated with retinal nerve fiber layer thickness in the PAC group (<i>P</i> = 0.045) but not correlated with the perfusion parameters in any subgroup. The mean deviation on Humphrey visual field was significantly worse in PAC eyes compared to PACS eyes (<i>P</i> = 0.02).</p><p><strong>Conclusion: </strong>Similar OCTA parameters were seen in normal, PACS, and PAC eyes without prior APAC, suggestive of absence of vascular factors in eyes without APAC in angle-closure disease. Functional impairment, despite similar structural and perfusion parameters in PAC eyes compared to PACS eyes, may be suggestive of ganglion cell dysfunction prior to loss.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"133-137"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gyrate atrophy of the choroid and retina with vitreous hemorrhage complication in a Vietnamese child.","authors":"Nguyen Minh-Phu, Nguyen Hanh Giang, Nguyen Ngan-Ha, Nguyen Huu Hong Thu, Nguyen Hai Ha","doi":"10.4103/ojo.ojo_247_24","DOIUrl":"10.4103/ojo.ojo_247_24","url":null,"abstract":"<p><p>Gyrate atrophy (GA) of the choroid and retina is a rare autosomal recessive inherited disease characterized by elevation of plasma ornithine levels due to deficiency of the mitochondrial enzyme <i>ornithine aminotransferase</i> resulting in progressive chorioretinal atrophy, nyctalopia, and possibly blindness. This report presents the case of a 7-year-old Vietnamese boy with no history of trauma and a complaint of sudden visual loss over the past 6 weeks. Fundus examination showed vitreous hemorrhage in the right eye and chorioretinal atrophy with hyperpigmented margins in the periphery retina of the left eye. Based on the high serum ornithine level and compound heterozygous mutations detected in the <i>ornithine aminotransferase</i> (<i>OAT</i>) gene of the patient, he was diagnosed with GA. The patient underwent a right eye vitrectomy and was supplemented with Vitamin B6 and an arginine-restricted diet. Four months after surgery, the patient's visual acuity was significantly improved, and there was no progression of chorioretinal atrophy or recurrent vitreous hemorrhage. GA is an extremely rare disease and difficult to diagnose, especially when accompanied by vitreous hemorrhage. Combining genetic tests with clinical examinations helped diagnose accurately, and prompt treatment could restore the patient's visual function.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"208-211"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of photokeratitis after a salon visit: A retrospective observational study.","authors":"Bipasha Mukherjee, Jay Kalliath, Sonia Mathew, Vijaya Natarajan, Sandeep Thirumalai, Rajesh Dalvi, Kavitha Avadhani","doi":"10.4103/ojo.ojo_392_24","DOIUrl":"10.4103/ojo.ojo_392_24","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to report the incidence of bilateral photokeratitis in patrons of hair-cutting salons following inadvertent exposure to ultraviolet (UV) rays from germicidal sterilizing cabinets.</p><p><strong>Materials and methods: </strong>It is a retrospective observational study of 30 patients who were diagnosed with UV-associated photokeratitis after a visit to a salon.</p><p><strong>Results: </strong>Thirty patients presented between January 2019 and November 2023, with bilateral conjunctival congestion with superficial punctate epithelial erosions typical of photokeratitis. All of them were males, aged between 27 and 64 years (mean = 35 years; median = 33 years). All of them gave a history of a visit to a salon within 24 h before the onset of symptoms. The typical onset of symptoms was seen after a few hours of exposure, ranging from 4 to 12 (mean = 7.4; median = 6.5 h). They were treated with topical lubricants and antibiotics. Six of them were reviewed after 24 h when five were asymptomatic and one patient developed a corneal epithelial defect.</p><p><strong>Conclusion: </strong>Germicidal UV lamps are used ubiquitously for disinfection in barbershops. This report highlights the risk of accidental exposure to such lamps and the need to increase awareness among the general public to prevent such accidents.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"172-176"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258850/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Objective and subjective outcomes following implantable collamer lens (ICL) implantation for the correction of myopia.","authors":"Gaurav Kapoor, Vijay Kumar Sharma, Prabhjot Singh, Deepti Sahran, Sankalp Seth, Vikas Ambiya, Nidhi Kalra, Avinash Mishra","doi":"10.4103/ojo.ojo_171_24","DOIUrl":"10.4103/ojo.ojo_171_24","url":null,"abstract":"<p><strong>Background: </strong>Implantable collamer lens (ICL) implantation has gained popularity as a surgical option for the correction of high myopia. This study aimed to evaluate the visual outcomes, patient satisfaction, and safety of ICL implantation by combining objective and subjective parameters for a comprehensive assessment.</p><p><strong>Methods: </strong>This prospective, interventional study included 67 eyes from 37 patients who underwent ICL implantation. Visual acuity, refractive outcomes, anterior chamber depth, ICL vault, endothelial cell density, intraocular pressure, and patient satisfaction using the Visual Function Questionnaire-25 (VFQ-25) were assessed preoperatively and at various postoperative time points up to 12 months.</p><p><strong>Results: </strong>At 12 months postoperatively, the mean uncorrected distance visual acuity improved to 0.10 ± 0.08 LogMAR, and the mean corrected distance visual acuity improved to 0.04 ± 0.05 LogMAR. The mean spherical equivalent decreased from -10.57 ± 2.22 D preoperatively to -0.10 ± 0.25 D, with 95.5% of eyes within ±0.50 D of the target refraction. The mean ICL vault was stable at 625 ± 80 μm, and no significant endothelial cell loss or complications were observed. The mean composite VFQ-25 score improved significantly from 72.87 ± 11.23 preoperatively to 93.39 ± 4.68 at 12 months postoperatively (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>This study demonstrates that ICL implantation is a safe, effective, and predictable option for the correction of high myopia, providing excellent visual outcomes, refractive stability, and significant improvements in patient satisfaction and quality of life. The combination of objective and subjective parameters provides a comprehensive assessment of surgical success and patient-reported outcomes.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"187-192"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to Letter to the Editor.","authors":"Gurcharan Singh, Shayri Pillai","doi":"10.4103/ojo.ojo_85_25","DOIUrl":"10.4103/ojo.ojo_85_25","url":null,"abstract":"","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"260"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinal nerve fiber layer defect secondary to cotton wool spots.","authors":"Tarannum Mansoori","doi":"10.4103/ojo.ojo_171_23","DOIUrl":"10.4103/ojo.ojo_171_23","url":null,"abstract":"","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"241-242"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of central and peripheral contrast sensitivity in myopes using Spaeth/Richman contrast sensitivity.","authors":"Parul Ichhpujani, Uday Pratap Singh Parmar, Rohan Bir Singh, Suresh Kumar","doi":"10.4103/ojo.ojo_271_23","DOIUrl":"10.4103/ojo.ojo_271_23","url":null,"abstract":"<p><strong>Background: </strong>Assessing central and peripheral contrast sensitivity (CS) in myopic patients with varying degrees of refractive error using Spaeth/Richman contrast sensitivity test (SPARCS) and compared it with emmetropic individuals.</p><p><strong>Materials and methods: </strong>CS of 50 consecutive myopic individuals of varying severity was matched with emmetropes using an online CS test, SPARCS, and Pelli-Robson test. Group comparisons for continuously distributed data were made using analysis of variance (ANOVA) when comparing the groups. A <i>post hoc</i> analysis was also done to compare pairs of each group. SPARCS scores were correlated with age and gender.</p><p><strong>Results: </strong>Data of 126 eyes, 96 eyes from 50 myopes and 30 eyes from 15 emmetropes, were analyzed. The total SPARCS scores of Groups 1, 2, 3, and 4 were 75.15 ± 9.59, 76.48 ± 7.74, 74.55 ± 7.48, and 86.43 + 5.3, respectively. Univariate ANOVA analysis revealed a statistically significant difference in total SPARCS score distribution in the three subgroups with myopia (<i>P</i> = 0.048) and between all the groups (<i>P</i> = 0.000). No statistically significant difference was seen between the groups when comparing the individual SPARCS scores with either age or gender.</p><p><strong>Conclusion: </strong>The study concludes that there is a significant difference in the CS in patients with varying severity of myopia and assessing peripheral CS is an important adjunct to central CS.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 1","pages":"16-21"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}