{"title":"Evaluation of optical coherence tomography in patients with coronary artery disease and systemic hypertension.","authors":"Shikha Bhardwaj, Farhat Abrar","doi":"10.4103/ojo.ojo_245_25","DOIUrl":"10.4103/ojo.ojo_245_25","url":null,"abstract":"<p><strong>Background: </strong>Systemic hypertension and coronary artery disease (CAD) cause widespread vascular and neurodegenerative changes, including in the retina. Optical coherence tomography (OCT) offers a noninvasive means to visualise these changes, serving as a potential marker of systemic vascular health. Retinal layers like the peripapillary retinal nerve fiber layer (p-RNFL) and ganglion cell-inner plexiform layer (GC-IPL) are especially vulnerable to vascular damage, making them useful indicators of cardiovascular risk. This study aimed to evaluate and compare the p-RNFL and GC-IPL thickness among hypertensive individuals with and without CAD and healthy controls.</p><p><strong>Materials and methods: </strong>This prospective observational study included 140 participants divided into three groups: healthy controls (Group A, <i>n</i> = 40), hypertensives without CAD (Group B, <i>n</i> = 50), and hypertensives with CAD (Group C, <i>n</i> = 50). All subjects underwent comprehensive ophthalmic evaluation, including spectral-domain-OCT, to measure p-RNFL and GC-IPL thickness in both eyes. Data were analyzed using analysis of variance with a significance threshold of <i>P</i> < 0.05.</p><p><strong>Results: </strong>Both p-RNFL and GC-IPL were significantly thinned in hypertensive subjects, especially those with CAD. Group A had the highest mean RNFL (114.11 ± 10.09 μm) and GC-IPL (85.07 ± 2.30 μm), whereas Group C showed the lowest (RNFL: 84.90 ± 11.81 μm; GC-IPL: 105.97 ± 11.72 μm). Differences were significant (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>OCT can find early signs of retinal nerve damage related to high blood pressure and CAD, indicating it can be a helpful noninvasive method for checking and tracking heart health risks.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 2","pages":"204-209"},"PeriodicalIF":0.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13404916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148605686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Delayed recognition of giant cell arteritis presenting as ear pain leading to vision loss: First biopsy-proven case encountered at a tertiary eye center in Oman.","authors":"Noor Saif A Al Jabri, Farida Wali M Al Belushi","doi":"10.4103/ojo.ojo_392_25","DOIUrl":"10.4103/ojo.ojo_392_25","url":null,"abstract":"<p><p>A 70-year-old Omani male with a history of poorly controlled diabetes, hypertension, and dyslipidemia presented with a 6-month history of persistent right ear and temporomandibular joint pain, culminating in sudden painless vision loss in the right eye and jaw claudication. Despite multiple prior consultations and misdiagnoses, the diagnosis of giant cell arteritis (GCA) was only made after ophthalmologic assessment revealed arteritic anterior ischemic optic neuropathy. Bilateral temporal artery biopsies confirmed GCA. The patient was managed with intravenous methylprednisolone, oral steroids, methotrexate, and later Tocilizumab. While systemic symptoms improved, vision loss was irreversible. This case underscores the diagnostic challenges of GCA in regions with low prevalence and highlights the importance of early recognition to prevent blindness.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 2","pages":"256-258"},"PeriodicalIF":0.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13404712/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148605457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A rare case of self-inflicted needle injury.","authors":"Tülay Karacan Ersekerci, Kemal Örnek","doi":"10.4103/ojo.ojo_446_25","DOIUrl":"10.4103/ojo.ojo_446_25","url":null,"abstract":"","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 2","pages":"275"},"PeriodicalIF":0.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13404705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148605753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Moein Zeinalddin, Ahmed Al Maskari, Ahmed Kenawy, Turkiya Al-Siyabi, Nagi Elsidig, Fahad Al Balushi, Anuradha Ganesh
{"title":"Successful management of pediatric <i>Pythium insidiosum</i> keratitis - A case report highlighting the role of targeted antimicrobial therapy and mechanical debridement.","authors":"Moein Zeinalddin, Ahmed Al Maskari, Ahmed Kenawy, Turkiya Al-Siyabi, Nagi Elsidig, Fahad Al Balushi, Anuradha Ganesh","doi":"10.4103/ojo.ojo_377_25","DOIUrl":"10.4103/ojo.ojo_377_25","url":null,"abstract":"<p><p>Human pythiosis keratitis is a rare but potentially sight-threatening infection. We report the case of an 8-year-old boy who developed a nonhealing corneal ulcer after finger nail trauma that did not respond to broad-spectrum antibiotics. Initial cultures identified <i>Staphylococcus warneri</i> and <i>Streptococcus mitis</i>. Worsening clinical signs prompted repeat investigations, which confirmed <i>Pythium insidiosum</i> through polymerase chain reaction. Despite intensive topical (natamycin and voriconazole) and systemic antifungals (voriconazole), the ulcer progressed with biofilm formation. Manual debridement and a revised regimen of topical linezolid 0.2% alternating with topical ceftazidime 5% led to significant clinical improvement. After 8 weeks of topical therapy and regular debridement, the infection eventually resolved with a paracentral scar and unaided visual acuity of 6/6. This case highlights the diagnostic complexity of <i>Pythium</i> keratitis and the crucial role of early microbial identification in pediatric ocular trauma. We attribute the successful management in this case to prompt diagnostic reevaluation, targeted antimicrobial therapy, and repeated scraping of ulcer biofilm.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 2","pages":"248-251"},"PeriodicalIF":0.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13404925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148605755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yusuf Evcimen, Ozgur Bulent Timucin, Burhan Baskan
{"title":"Vertical phakic intraocular lens implantation yields superior astigmatic stability compared to horizontal orientation: A retrospective analysis.","authors":"Yusuf Evcimen, Ozgur Bulent Timucin, Burhan Baskan","doi":"10.4103/ojo.ojo_156_25","DOIUrl":"10.4103/ojo.ojo_156_25","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the effect of the implantation meridian (horizontal or vertical) of the Eyecryl phakic intraocular lens (pIOL) on ocular residual astigmatism (ORA), anterior chamber depth (ACD), and vault height.</p><p><strong>Methods: </strong>A total of 44 eyes were retrospectively analyzed and divided into two groups based on the meridian of pIOL implantation: horizontal (<i>n</i> = 16) and vertical (<i>n</i> = 28). Keratometry, refractive astigmatism, ORA, ACD, and vault height were compared between the groups.</p><p><strong>Results: </strong>A significant postoperative increase in ORA was observed in the horizontal group (<i>P</i> < 0.001), whereas ORA remained stable in the vertical group. ACD reduction was more pronounced in the horizontal group (<i>P</i> = 0.006). No significant difference was found between the groups in terms of changes in vault height (<i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>In this study, ORA values remained stable in the group with vertically implanted pIOLs during both the preoperative and postoperative periods. This finding suggests that vertical implantation provides more stable refractive outcomes.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 2","pages":"223-227"},"PeriodicalIF":0.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13404932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148605802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antiplatelets and anticoagulants in glaucoma surgery and laser.","authors":"Hemlata Udenia, Sushmita Bairagi, Dewang Angmo, Nitika Beri, Deepti Siddharthan, Renu Sinha, Namrata Sharma, Tanuj Dada","doi":"10.4103/ojo.ojo_215_24","DOIUrl":"10.4103/ojo.ojo_215_24","url":null,"abstract":"<p><p>With the increasing prevalence of cardiovascular diseases, it has become common for patients to be on different classes of anticoagulant medications. The blood-thinning characteristic of these drugs makes them essential for the management of long-term comorbidities, but it also raises the possibility of hemorrhagic complications during and after ophthalmic surgery. Although there is some agreement regarding the preoperative use of anticoagulant drugs in cataract surgery, little is known about the continuation or discontinuation of these drugs before surgeries for glaucoma. Regarding the use of anticoagulants before glaucoma surgery, surgeons' practices differ greatly. Anticoagulation therapy must be understood in the context of glaucoma surgery and laser treatment, as the evidence currently available is inconclusive regarding the benefits of continuing/withholding anticoagulation or using bridging therapy. Modifying anticoagulation therapy for glaucoma surgery must be done carefully and after consulting primary care physicians, internists, cardiologists, and neurologists due to the potential serious adverse effects of stopping the treatment.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 2","pages":"174-182"},"PeriodicalIF":0.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13404719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148605074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fungal keratitis after conjunctivitis.","authors":"Kshiti Saruparia, Isha Chaudhari, Shweta Singh","doi":"10.4103/ojo.ojo_139_25","DOIUrl":"10.4103/ojo.ojo_139_25","url":null,"abstract":"<p><p>Self-medication, over-the-counter medication, and injudicious use of eye drops are not uncommon in our society. Use of such over-the-counter drugs without proper knowledge may be a convenient or cheaper alternative in some scenarios but can have serious implications. With this case series, we intend to highlight one of the risks associated with inappropriate steroid use. We describe the case of three patients who presented with <i>Fusarium</i> keratitis after an episode of conjunctivitis and prolonged use of steroids. All three patients had varying outcomes, ranging from successful medical management to the needing a therapeutic penetrating keratoplasty. This study underscores the critical need for judicious prescription practices. Enhanced diagnostic vigilance and patient education on the risks of self-medication with steroids are essential to mitigate the incidence of this sight-threatening condition.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 2","pages":"244-247"},"PeriodicalIF":0.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13404930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148605656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Goudappa Patil, Premika Pandarasamy, N V S Krishna Reddy, Pratyusha Ganne
{"title":"Rod-cone dystrophy with myriad systemic manifestations.","authors":"Goudappa Patil, Premika Pandarasamy, N V S Krishna Reddy, Pratyusha Ganne","doi":"10.4103/ojo.ojo_134_25","DOIUrl":"10.4103/ojo.ojo_134_25","url":null,"abstract":"<p><p>Rod-cone dystrophy (RCD) is an inherited retinal disorder primarily affecting rod photoreceptors, followed by cone degeneration. We present the case of a 26-year-old male with RCD and multiple systemic abnormalities (atrial septal defect, hypogonadism, liver disease with gastric varices, hypertriglyceredemia, hypothyroidism, adrenal insufficiency, and delayed epiphyseal closure) in the same individual. Ophthalmic evaluation revealed retinal pigment epithelial atrophy, bone spicule pigmentation, a macular hole in the right eye, and an epiretinal membrane in the left. Genetic testing identified a heterozygous ABCA4 c.3113C>T (p.Ala1038Val) mutation, previously associated with retinal dystrophies. We postulate that this case represents a unique blended phenotype, i.e., retinal disease due to ABCA4 and multiple systemic issues due to an unidentified syndrome.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 2","pages":"267-270"},"PeriodicalIF":0.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13404936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148605791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Delvi Indera Mayasari, Ulfah Rimayanti, Marlyanti Nur Rahmah, Purnamanita Syawal
{"title":"Comparison of refractive examination results in children with and without cycloplegia using retinoscopy and autorefractors.","authors":"Delvi Indera Mayasari, Ulfah Rimayanti, Marlyanti Nur Rahmah, Purnamanita Syawal","doi":"10.4103/ojo.ojo_100_25","DOIUrl":"10.4103/ojo.ojo_100_25","url":null,"abstract":"<p><strong>Context: </strong>Uncorrected refractive errors are the most common cause of visual impairment and global blindness.</p><p><strong>Aims: </strong>This study aims to assess the accuracy of refractive error measurements using streak retinoscopy and autorefraction, both with and without administering cycloplegics, in children aged 4-10 years.</p><p><strong>Settings and design: </strong>This study is an analytical observational research with a cross-sectional design.</p><p><strong>Subjects and methods: </strong>This study was conducted at an eye clinic from January 2020 to August 2020, with 90 subjects. The examination utilized 1% cyclopentolate cycloplegia administered twice within 1 h, along with retinoscopy and autorefractors.</p><p><strong>Statistical analysis used: </strong>The data were analyzed using the Wilcoxon signed-rank test.</p><p><strong>Results: </strong>The study results indicate that (1) there was no significant difference in the mean spherical equivalent (SE) before cycloplegia between the two instruments (<i>P</i> = 0.630); (2) a significant difference in mean SE after cycloplegia was observed for both instruments (<i>P</i> < 0.001); (3) significant differences in mean SE after cycloplegia were noted for both instruments in cases of compound myopic astigmatism (<i>P</i> < 0.001), compound hyperopic astigmatism (<i>P</i> = 0.007), and mixed astigmatism (<i>P</i> = 0.001); and (4) examination of all subjects showed undercorrection of autorefractometry results compared to those of retinoscopy.</p><p><strong>Conclusions: </strong>Retinoscopy and autorefractors yield different results for refractive error correction after cycloplegia. Therefore, autorefractor examination with cycloplegia cannot be considered a substitute for retinoscopy with cycloplegia.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 2","pages":"232-238"},"PeriodicalIF":0.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13404713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148605447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}