Oman Journal of Ophthalmology最新文献

{"title":"Evaluation of corneal endothelial cell loss following vitrectomy with different endotamponades.","authors":"Kirti Rani, Anil Solanki, Neha Agarwal, Shashi Nath Jha, Ritika Aggarwal","doi":"10.4103/ojo.ojo_258_24","DOIUrl":"10.4103/ojo.ojo_258_24","url":null,"abstract":"<p><strong>Context: </strong>Ensuring functional corneal endothelium is imperative for achieving optimal surgical outcomes following successful vitreoretinal surgery. Despite the critical role of the corneal endothelium in postoperative recovery, limited research has addressed endothelial cell damage specifically attributed to vitreoretinal procedures. This knowledge gap necessitates further investigations to better understand the potential loss of corneal endothelial cells (CECs) associated with vitreoretinal surgery.</p><p><strong>Aims: </strong>To evaluate the effect of vitreoretinal surgery on CECs by using different endotamponading agents.</p><p><strong>Settings and design: </strong>Prospective, nonrandomized, comparative, and observational study.</p><p><strong>Subjects and methods: </strong>Patients (<i>n</i> = 32) were divided into three groups: C3F8 gas (Group A), silicone oil (Group B), and Ringer Lactate (Group C). Corneal endothelial parameters including, the corneal endothelial cell density (ECD), average cell area (AVG), coefficient of variation (CV), central corneal thickness (CCT), and percentage of hexagonal cells (HEX) were assessed preoperatively, at 1 month, and 3 month postsurgery.</p><p><strong>Statistical analysis used: </strong>SPSS software version 16.0, Kolmogorov-Smirnov, Wilcoxon, and Chi-square tests were used. Statistical significance was set at <i>P</i> < 0.05.</p><p><strong>Results: </strong>Significant differences in the changes in ECD and CCT were observed between the groups (<i>P</i> > 0.05). However, AVG, CV and HEX were not significantly different between the groups. No significant differences in the changes in endothelial cell parameters were noted between phakic and pseudophakic eyes.</p><p><strong>Conclusions: </strong>CEC damage following vitrectomy with different endotamponades is a crucial consideration in vitreoretinal surgery. Vitreoretinal surgeons must carefully weigh the benefits and risks associated with different tamponade agents to safeguard corneal health in vitreoretinal surgeries.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"150-154"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of cenegermin for the management of neurotrophic keratopathy after penetrating keratoplasty.","authors":"Alexandra R Zaloga, Ashley Khalili, Brandon D Ayres, Brenton D Finklea, Beeran B Meghpara, Christopher J Rapuano, Zeba A Syed","doi":"10.4103/ojo.ojo_311_24","DOIUrl":"10.4103/ojo.ojo_311_24","url":null,"abstract":"<p><strong>Background: </strong>The study aimed to report the outcomes of patients treated with cenegermin 0.002% for neurotrophic keratopathy (NK) following penetrating keratoplasty (PK).</p><p><strong>Materials and methods: </strong>This retrospective case series included patients evaluated at a tertiary care hospital who completed an 8-week course of cenegermin for NK within 12 months following PK. The primary outcome measure was NK stage, while secondary outcomes included complete epithelial healing, epithelial defect size, and best-corrected visual acuity (BCVA) at baseline and four time points during and following treatment. We also evaluated disease progression.</p><p><strong>Results: </strong>Fourteen eyes of 14 patients were included and demonstrated significant improvement in NK stage at 4 weeks (1.1 ± 0.7; <i>P</i> = 0.006) and 8 weeks after treatment initiation (0.9 ± 0.7; <i>P</i> = 0.002) and 1 month (0.6 ± 0.5; <i>P</i> < 0.001) and 6 months after treatment completion (0.8 ± 0.9; <i>P</i> = 0.002) compared to baseline (1.6 ± 0.5). Complete epithelial healing was noted 1 month (42.9%; <i>P</i> = 0.016) and 6 months after treatment completion (38.5%; <i>P</i> = 0.016). Epithelial defect size improved to <5 mm² at all points (<i>P</i> < 0.05) during and after treatment compared to baseline (37.24 mm²). Improvement in BCVA was not significant at any time point. Two (14.3%) patients experienced disease progression up to 6 months of follow-up.</p><p><strong>Conclusions: </strong>Following an 8-week course of cenegermin, patients with a history of PK demonstrated improvement in NK stage, epithelial healing, and reduced epithelial defect size lasting 6 months after treatment completion. Patients with prior PK and NK may be considered candidates for cenegermin treatment.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"198-204"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive decline, dual sensory loss and the use of visual aids in elderly - A narrative review.","authors":"Sourav Karmakar, Animesh Mondal, Pampa Bhowmick, Gaurav Kumar Bhardwaj","doi":"10.4103/ojo.ojo_177_23","DOIUrl":"10.4103/ojo.ojo_177_23","url":null,"abstract":"<p><p>The relationships between visual acuity, contrast sensitivity, stereo acuity, and cognition varied, implying that domain-specific cognitive loss patterns exist. This review aims to learn how visual aids help patients with visual impairment and cognitive decline. The electronic searches had no language restrictions or research design filters. However, from 2016 forward, searches were restricted, and the electronic databases were last examined in 2022. There were 537 papers discovered in PubMed and 18,000 articles found in Google Scholar, of which ten articles fit the criteria. Patients who participated in the trials had an average age of 81-82 years. Patients with self-reported vision difficulties had a higher incidence of dementia. The majority were female populations. Auditory and visual loss was detected in 5.5% of dementia cases versus 4.9% of nondementia subjects. Early-stage cognitive impairment raises the chance of dementia later in the disease. Along with motor dysfunction, impairments in visual memory, verbal fluency, and executive functions, as well as increased depressive symptoms, predicted worse Parkinsonian disability, highlighting the critical role of nonmotor factors such as cognitive and visual dysfunction, as well as depression, in disability, even in the early stages of Parkinsonian disability.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"113-120"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corneal epithelial thickness profile at different corneal zones of normal eyes in a population sample from northern Iran: A cross-sectional study.","authors":"Reza Soltani Moghadam, Mitra Akbari, Parisa Rouhani, Abdolreza Medghalchi, Ehsan Kazemnezhad Leili, Ebrahim Azaripour","doi":"10.4103/ojo.ojo_236_23","DOIUrl":"10.4103/ojo.ojo_236_23","url":null,"abstract":"<p><strong>Background: </strong>Determination of the normal range of corneal epithelial thickness (CET) profiles in different populations is important. Accordingly, the present study aimed to investigate the CET in normal eyes in Guilan province of Iran.</p><p><strong>Materials and methods: </strong>In this cross-sectional study, a total of 169 patients (18-60 years old) who were referred to the ophthalmology clinics in Rasht for corneal refractive surgery were included. They underwent a complete ophthalmological examination, including visual acuity, intraocular pressure examination, and fundoscopy examination with a 90 D lens. Spectral-domain optical coherence tomography was used to examine CET; corneal epithelial mapping was done with Optovue I scan 500s.</p><p><strong>Results: </strong>The mean CET at 5-6 mm and 2-5 mm zones was 52.88 ± 2.8 and 53.24 ± 2.9, in the 2 mm of the center was 53.67 ± 3.24, in the superior and inferior 5-6 mm zone was 50.8 ± 3.18 and 54.38 ± 3.53, and in superior and inferior 2-5 mm zone was 52.14 ± 2.98 and 54.41 ± 3.60, respectively; there was a significant difference between 5-6 and 2-5 mm of the superior zone. The supratemporal region had the thinnest epithelium, and the inferior region had the thickest. The central CET was statistically different between males and females, and the relationship between paracentral and peripheral thickness (2-5 and 5-6 mm) with age, especially in ages 33-46 and 47-60, was stronger.</p><p><strong>Conclusion: </strong>The values of the CET map, defined in the present study, in a sample of Guilan population with normal eyes, can be further used as a reference (normal) range for this population.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"144-149"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corneal melting following intrastromal injection of bevacizumab for corneal neovascularization.","authors":"Muna Salim Al-Ruhaili, Haitham Hilal Al-Mahrouqi","doi":"10.4103/ojo.ojo_344_24","DOIUrl":"10.4103/ojo.ojo_344_24","url":null,"abstract":"<p><p>The aim is to report corneal melting following intrastromal injection of antivascular endothelial growth factor (anti-VEGF), bevacizumab, for pre-existing corneal neovascularization. A 68-year-old male with a history of failed bilateral penetrating keratoplasties due to scarring from childhood measles and trachoma underwent right eye superficial keratectomy, intrastromal bevacizumab, and amniotic membrane transplant to control the neovascularization in an overseas center. A week later developed corneal melting. In conclusion, anti-VEGF can be used in controlling corneal neovascularization, albeit, is associated with risks such as delayed epithelial healing and corneal melting, particularly in those with limbal stem cell deficiency.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"205-207"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolated conjunctival lymphangioma.","authors":"Ritesh Verma, Aminder Singh, Buse Guneri Beser","doi":"10.4103/ojo.ojo_423_24","DOIUrl":"10.4103/ojo.ojo_423_24","url":null,"abstract":"","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"253-254"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous inverse couching.","authors":"Lipi Mittal, Mayank Sharma, Sandeep Choudhary","doi":"10.4103/ojo.ojo_354_24","DOIUrl":"10.4103/ojo.ojo_354_24","url":null,"abstract":"","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"255-256"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anterior segment optical coherence tomography: A monitoring tool in anterior scleritis.","authors":"Saloni Desai, Jyotirmay Biswas, Sudha K Ganesh, Darshan Bhatt","doi":"10.4103/ojo.ojo_376_24","DOIUrl":"10.4103/ojo.ojo_376_24","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to evaluate the role of anterior segment optical coherence tomography (ASOCT) in the diagnosis and management of anterior scleritis.</p><p><strong>Patients and methods: </strong>In this retrospective study, we examined 58 eyes of 44 patients with anterior scleritis. The unaffected eye served as a control. In bilateral cases, the less affected eye was taken as the control. ASOCT image over the inflamed area and over the corresponding same area in the control eye was taken. The images were analysed for the presence or absence of hyporeflective areas, and the mean total scleral thickness (MTST) was measured. Both the images were then compared.</p><p><strong>Results: </strong>The mean age of our cohort was 51 ± 14.57 years. There were 14 males and 30 females. 68.18% (<i>n</i> = 30) were unilateral cases. The mean duration of anterior scleritis was 55.3 months, with 50% (<i>n</i> = 22) of patients having diffuse anterior scleritis. The majority of patients were treated with oral steroids (97.7%, <i>n</i> = 43) with or without the combination of immunosuppressant and biologics. The MTST during active disease (922.17 μm ± 252.03 μm) was statistically higher than the control group (798.05 μm ± 150.61 μm) (<i>P</i> = 0.005). The MTST in unilateral cases during active disease was 929.88 μm, which was significantly higher than in the control eyes (801.65 μm) (<i>P</i> = 0.02). There were 31 recurrent cases, of which 41.9% (<i>n</i> = 13) showed scleral thinning, and the mean scleral thinning in recurrent cases after treatment was 86.71 μm.</p><p><strong>Conclusion: </strong>ASOCT serves as a useful qualitative and quantitative tool for monitoring of patients with anterior scleritis under treatment.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"155-161"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crystals and cookies: Different appearances of calcium deposits on intraocular lens.","authors":"Dhanashree Ratra, Jyotirmay Biswas, Vineet Ratra, Ramavath Sree Keerti, J S Deepikasri, Uyanga Bayarsaikhan, Devika Pradeep Damle","doi":"10.4103/ojo.ojo_324_24","DOIUrl":"10.4103/ojo.ojo_324_24","url":null,"abstract":"","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"246-247"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immediate sequential bilateral cataract surgery: Is it time to change?","authors":"Haitham Hilal Al-Mahrouqi, Malyar Mohsin Al-Marhoon","doi":"10.4103/ojo.ojo_112_25","DOIUrl":"10.4103/ojo.ojo_112_25","url":null,"abstract":"","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"110-112"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}