{"title":"Impact of global shortage of verteporfin (visudyne<sup>®</sup>) on photodynamic therapy.","authors":"Ahmed S Al-Hinai","doi":"10.4103/ojo.ojo_99_25","DOIUrl":"10.4103/ojo.ojo_99_25","url":null,"abstract":"","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"107-109"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Mejbahul Alam, Zahedur Rahman, Krishnakumar Subramanian, Parthopratim Dutta Majumder
{"title":"Tuberculous endogenous endophthalmitis presenting acute anterior uveitis with hypopyon.","authors":"M Mejbahul Alam, Zahedur Rahman, Krishnakumar Subramanian, Parthopratim Dutta Majumder","doi":"10.4103/ojo.ojo_87_24","DOIUrl":"10.4103/ojo.ojo_87_24","url":null,"abstract":"<p><p>A 27-year-old male with pain, redness, and vision loss in the right eye was diagnosed with acute anterior uveitis with hypopyon and treated with topical corticosteroid and cycloplegic eyedrops. Two weeks later, he developed severe vitritis. Then, after 1 month of oral corticosteroid treatment, his condition did not improve; therefore, he underwent pars plana vitrectomy with intravitreal antimicrobial injection in the right eye with suspicion of endogenous endophthalmitis. Polymerase chain reaction (PCR) from vitreous aspirate were negative for herpes viruses, eubacterial and panfungal genomes. After 3 months, the patient developed a painful blind eye and was eviscerated. Histopathology and PCR from ocular specimens confirmed the presence of <i>Mycobacterium tuberculosis</i>. High-resolution computed tomography chest showed calcific nodules in the upper lobe of the right lung, and the Mantoux test was positive. Further inquiry revealed that the patient's father had pulmonary tuberculosis (TB) 4 years earlier. Ocular TB remains a great masquerader; the clinicians in the TB-endemic region must bear a high index of suspicion of TB while managing a case of endogenous endophthalmitis.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"221-223"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Uveitis in Parry-Romberg syndrome: A case report and review of literature.","authors":"Parthopratim Dutta Majumder, Anitha Manoharan, Harshita Atmakur, Anindya Kishore Majumder","doi":"10.4103/ojo.ojo_56_24","DOIUrl":"10.4103/ojo.ojo_56_24","url":null,"abstract":"<p><p>Parry-Romberg syndrome (PRS) is a rare, acquired condition characterized by progressive atrophy of the skin and soft tissue of one side. A 35-year-old female with a 4-year history of recurrent uveitis and hypotony in the right eye, previously diagnosed with granulomatous anterior uveitis and pars planitis, was referred to our clinic. Despite treatment, she continued to develop recurrences of inflammation, with intraocular pressure dropping to 0 mmHg twice. She was managed with periocular injection triamcinolone acetonide with systemic anti-inflammatory treatment. A dermatology consultation was sought based on a general examination that revealed hyperpigmented lesions on the right side of the forehead and scalp, as well as alopecia patches. The dermatologist diagnosed her with PRS. She was managed with oral methotrexate and subsequently did not develop any further recurrence of inflammation or hypotony. A literature search revealed 23 cases of PRS with uveitis. Most cases reported an early onset of PRS preceding a uveitis episode. The most common subtypes of uveitis were retinal vasculitis and Coats'-like response that were associated with inflammation in the anterior chamber and vitreous. PRS can be a rare cause of uveitis but can be often overlooked by clinicians. Such patients should be monitored closely, as they may develop ocular hypotony over time, but can be managed with aggressive treatment.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"216-220"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endocrine mucin-producing sweat gland carcinoma of eyelid as a presenting feature of breast carcinoma in a male patient.","authors":"Tanisha Sehgal, Ritesh Verma, Aminder Singh, Yesha Gupta","doi":"10.4103/ojo.ojo_190_24","DOIUrl":"10.4103/ojo.ojo_190_24","url":null,"abstract":"<p><p>Endocrine mucin-producing sweat gland carcinoma (EMPSGC) is a rare indolent tumor with predilection for periocular skin of elderly women. Although recurrences may occur, metastases are uncommon with EMPSGC. We present a case of EMPSGC of the eyelid as a presenting feature of invasive carcinoma of the breast in a male patient. A 71-year-old male presented with a right eyelid mass from the past 6 months. A wide excision biopsy with intraoperative frozen section margin control and reconstruction was done. Histopathology and immunohistochemistry (IHC) were suggestive of EMPSGC. On systemic examination, the patient had a breast mass 2 cm × 3 cm × 1 cm which he did not reveal at presentation. A Trucut biopsy was performed, and the histopathology was similar to the eyelid tumor. On positron emission tomography (PET) scan, there was uptake in the breast mass, axillary and mediastinal lymph nodes, and multiple nodular lesions in the lungs were noted. The patient underwent BRCA1/2 mutation test which revealed a variance of uncertain significance. In view of hormone receptor positivity, the patient was then started on hormonal therapy and the tumor showed significant regression on serial examination and successive PET scans. We discuss the management of the eyelid lesion and compare the histopathology and IHC of the primary and metastatic tumor.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"228-231"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258855/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endoscopic-guided monocanalicular versus bicanalicular Ritleng intubation for treating congenital nasolacrimal duct obstruction in patients aged 24-53 months.","authors":"Walid Mohamed Abdalla, Eman N Sultan","doi":"10.4103/ojo.ojo_250_24","DOIUrl":"10.4103/ojo.ojo_250_24","url":null,"abstract":"<p><strong>Background: </strong>Congenital nasolacrimal duct obstruction (CNLDO) is a common condition in neonates, often requiring intervention when conservative treatments and simple probing fail. This study aimed to explore the efficiency and safety of endoscopic-guided bicanalicular (BC) and monocanalicular (MC) Ritleng intubation in treating CNLDO.</p><p><strong>Methodology: </strong>This multicenter, prospective, nonrandomized comparative study was conducted between 2007 and 2022. The study included a total of 90 patients aged 24-53 months who had either failed probing or presented late with CNLDO. The participants were divided into two groups: 45 treated with BC and the other 45 with MC Ritleng intubation. Surgical procedures were performed under general anesthesia. Follow-up visits were scheduled at 1 week postoperatively, then at 1 month, and 3 months after stent removal. Finally, postoperative outcomes were analyzed.</p><p><strong>Results: </strong>The clinical success rates were comparable, with BC achieving 93.3% and MC achieving 92.2% (<i>P</i> = 0.68). BC intubation was associated with a higher complication rate (28.9%) compared to MC (4.4%), with a statistically significant difference (<i>P</i> = 0.004). The study also revealed the absence of significant associations between the incidence of complications and age, gender, or preexisting conditions (<i>P</i> = 0.90).</p><p><strong>Conclusions: </strong>Both BC and MC Ritleng intubation are effective treatments for late-presenting CNLDO and cases following failed probing. However, MC intubation stands out as a safer and quicker option, significantly reducing the risk of complications. This study emphasizes the advantages of MC Ritleng intubation for pediatric patients with CNLDO.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"193-197"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258858/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hyphaema, heterochromia and hyperpigmented cutaneous nodules.","authors":"Nidhi Mamtani, Sagarika Snehi, Puja Hingorani Bang, Kanishk Singh, Rajesh Pattebahadur, Meghana Kandi, Sachin Chaudhari, Pankaj Dwivedi","doi":"10.4103/ojo.ojo_296_24","DOIUrl":"10.4103/ojo.ojo_296_24","url":null,"abstract":"<p><p>Juvenile xanthogranuloma (JXG) is a rare, benign granulomatous disorder predominantly affecting young children, characterized by the presence of Touton giant cells. While typically presenting as cutaneous lesions, JXG can also involve the eyes, potentially leading to severe complications such as hyphema and glaucoma. Here, we present the case of an 11-month-old girl with multifaceted systemic and ocular manifestations of JXG. She presented with unilateral redness, watering, photophobia, and hyperpigmented nodules distributed across her body. Ocular examination revealed hyphema, heterochromia iridis, fibrinous reaction, and elevated IOP with signs of glaucomatous optic neuropathy. Despite initial treatment with topical steroids and antiglaucoma medications, the patient experienced recurrent hyphema. Further evaluation identified peripheral anterior synechiae and delicate vessels spanning the trabecular meshwork. Histopathological analysis of the skin nodules confirmed the diagnosis of JXG, with systemic involvement noted in the spleen and other organs. Multidisciplinary management, including chemotherapy, resulted in the regression of hyphema and the fibrinous reaction. This case underscores the importance of comprehensive evaluation and a multidisciplinary approach in managing JXG, highlighting the challenges faced by ophthalmologists in preventing complications such as rebleeding and refractory glaucoma.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"235-238"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neodymium-doped yttrium aluminum garnet laser for minimally invasive management of limbal cysts in allergic conjunctivitis.","authors":"Avadhesh Oli, Agrima Bhatia","doi":"10.4103/ojo.ojo_93_24","DOIUrl":"10.4103/ojo.ojo_93_24","url":null,"abstract":"<p><p>Allergic conjunctivitis is a widely prevalent disease across the globe. Conjunctival congestion and papillae are the most common ocular manifestations. Limbal involvement in the form of limbitis is common but limbal cysts are very rare. We present a rare case of bilateral conjunctival inclusion cysts secondary to allergic conjunctivitis, successfully managed with neodymium-doped yttrium aluminum garnet (Nd: YAG) laser photodisruption. Unwilling for surgical excision, Nd: YAG laser was considered a minimally invasive, nonsurgical option to rupture the cysts. Over a follow-up period of seven months, all the cysts disappeared and the patient became symptom-free. This modality can be considered a minimally invasive alternative outpatient procedure to surgical excision with good outcomes, especially in cases with multiple small inclusion cysts as in our case.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"232-234"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Priyanka Pramod Dhande, Nisha V Ahuja, Neel Shaileshbhai Shah
{"title":"The outcome of uveal coloboma patients undergoing manual small incision cataract surgery and intraocular lens implantation.","authors":"Priyanka Pramod Dhande, Nisha V Ahuja, Neel Shaileshbhai Shah","doi":"10.4103/ojo.ojo_114_23","DOIUrl":"10.4103/ojo.ojo_114_23","url":null,"abstract":"<p><strong>Aims: </strong>The aim is to study the outcome of uveal coloboma patients undergoing manual small incision cataract surgery (MSICS) and intraocular lens (IOL) implantation.</p><p><strong>Subjects and methods: </strong>The study included 14 patients with uveal coloboma who underwent small incision cataract surgery and IOL implantation between March 2022 and February 2023. The systemic analysis of preoperative, intraoperative, and postoperative data was done.</p><p><strong>Results: </strong>The average patient age at the time of surgery was 58.5 years (range 45-74 years). Out of a total of 14 patients, 10 patients had unilateral coloboma and four patients had bilateral presentation. Of these, two patients had only one functioning eye, two had bilateral microcornea, and two had unilateral phacodonesis. Small incision cataract surgery was performed in all cases in one eye. Intraoperative zonular dialysis was noted in five cases where a capsular tension ring was used in two cases and IOL was placed in the bag and an iris-claw was tucked in three cases. Two patients had descemets membrane detachment, where DM repositioning was done with air. None of the cases underwent pupilloplasty.</p><p><strong>Conclusions: </strong>The cataract patient with congenital iridochoroidal coloboma can be better managed with an MSICS. Although phacoemulsification is the treatment of choice nowadays, a small incision cataract surgery can be considered rescuer in a patient with a hard cataract and microcornea.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"177-181"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vision related quality of life in keratoconus patients with intra stromal corneal ring segments implantation.","authors":"Sahar Mohaghegh, Shahram Bamdad, Haleh Kangari, Mohammad Reza Khalili, Sharafat Javaheri","doi":"10.4103/ojo.ojo_228_23","DOIUrl":"10.4103/ojo.ojo_228_23","url":null,"abstract":"<p><strong>Background: </strong>To evaluate the vision-related quality of life in keratoconus patients who had undergone intrastromal-corneal-ring-segment (ICRS) implantation using the Persian version of Vision-Function-Questionnaire-25.</p><p><strong>Methods: </strong>In a cross-sectional study, 20 keratoconus patients, mean age 33.50 ± 5.50 years old, managed with bilateral ICRS implantation were included. Thirty age- and sex-matched normal individuals mean age of 30.00 ± 6.20 years old were included in the control group. The binocular visual acuity and vision-related quality of life were compared between the ICRS and control groups. The Persian version of Vision-Function Questionnaire-25 was applied.</p><p><strong>Results: </strong>The mean binocular best corrected visual acuity in the keratoconus group was 0.06 ± 0.08 logarithm of the minimum angle of resolution (LogMAR), and in normal individuals was 0.00 ± 0.00 LogMAR, (<i>P</i> = 0.001). The mean total score of Vision-Function-Questionnaire-25 in the ICRS group was 81.00 ± 14.00, and in the control group was 90.50 ± 8.00 (<i>P</i> = 0.004). The ICRS group showed significantly lower scores in distance vision, near vision, peripheral vision, role limitation, and night-time driving, <i>P</i> < 0.05. The differences in the mean values of social function, dependency, day driving, ocular pain, and color vision were insignificant compared to normal individuals (<i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>ICRS implantation can improve some social functions of keratoconus patients to the level of normal individuals; however, visual functions and night driving remain affected compared to normal individuals.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 2","pages":"162-166"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}