Oman Journal of Ophthalmology最新文献_第5页

Atypical presentation of persistent fetal vasculature with Berger's space hemorrhage: Challenges in surgical management. 持续胎儿血管与伯杰氏间隙出血的不典型表现：手术处理的挑战。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_264_22

Sushma Jayanna, Tapas Ranjan Padhi, Komal Agarwal, Subhadra Jalali

引用次数: 0

Fungal keratitis treatment: Unveiling strategies and emerging trends - A systematic review. 真菌性角膜炎治疗：揭示策略和新趋势-系统综述。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_67_25

Gabriella Hafidha Badruddin, Stella Nathania, Lukman Edwar

{"title":"Fungal keratitis treatment: Unveiling strategies and emerging trends - A systematic review.","authors":"Gabriella Hafidha Badruddin, Stella Nathania, Lukman Edwar","doi":"10.4103/ojo.ojo_67_25","DOIUrl":"10.4103/ojo.ojo_67_25","url":null,"abstract":"This study evaluates the efficacy of antifungal medications for fungal keratitis through a systematic review in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. A comprehensive search of PubMed, Cochrane, and ScienceDirect was performed, including randomized controlled trials (RCT), cohort, and case-control studies on antifungal therapy for fungal keratitis. Keywords and MeSH terms, including \"keratitis,\" \"fungal keratitis,\" \"antifungal,\" and \"therapy,\" were used to identify relevant studies. The screening process was facilitated through Rayyan, an online-based platform. The inclusion criteria were English-language, full-text human studies on antifungal therapy. Data extraction included study details, interventions, outcomes, and adverse effects, with efficacy evaluated on a scale of 0-2 based on clinical outcomes. Twelve RCT involving 1.715 adult patients from India, China, and Nepal were reviewed. The mean patient age was 48.1 years, with males predominating. All studies used 5% natamycin eye drops, with seven incorporating voriconazole in various forms. Additional therapies included chlorhexidine, amphotericin B, ciprofloxacin, levofloxacin, hypochlorous acid (HOCI), and ketoconazole. Seven studies reported significant improvements in best-corrected visual acuity, infiltrate size, and treatment success. Natamycin monotherapy was shown to have the highest efficacy with a score of 11. Combination therapies, including voriconazole showed effectiveness but with slightly lower scores. In severe cases, combining natamycin with systemic antifungals such as voriconazole, ketoconazole, or amphotericin B was necessary for optimal outcomes.","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 1","pages":"37-47"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13043117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intracameral perfluoropropane for the management of acute hydrops following keratoconus recurrence in a corneal graft. 眼内全氟丙烷治疗角膜移植术后圆锥角膜复发急性积液。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_422_24

Ritu Arora, Abhilasha Sanoria, Rushad Shroff, Palak Gupta, Apoorva Aggarwal

引用次数: 0

Oral cyclophosphamide as part of the treatment regimen in patients with nonparaneoplastic autoimmune retinopathy secondary to birdshot chorioretinopathy. 口服环磷酰胺作为鸟射性脉络膜视网膜病变继发的非副肿瘤性自身免疫性视网膜病变患者治疗方案的一部分

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_126_24

Diana Morvey, Arash Maleki, Paula Vivian Tan, C Stephen Foster

{"title":"Oral cyclophosphamide as part of the treatment regimen in patients with nonparaneoplastic autoimmune retinopathy secondary to birdshot chorioretinopathy.","authors":"Diana Morvey, Arash Maleki, Paula Vivian Tan, C Stephen Foster","doi":"10.4103/ojo.ojo_126_24","DOIUrl":"10.4103/ojo.ojo_126_24","url":null,"abstract":"The purpose of this case series is to delineate the rationale for employing oral cyclophosphamide along with rituximab in three patients with nonparaneoplastic autoimmune retinopathy (npAIR) secondary to birdshot chorioretinopathy. Case 1: A 50-year-old male with a history of amblyopia in the right eye (OD) presented with floaters and reduced vision in the OD. He was diagnosed with birdshot chorioretinopathy (BSCR) in both eyes (OU). He was successfully treated with cyclosporine and mycophenolate mofetil; however, later, he developed npAIR. He started rituximab infusion and oral cyclophosphamide. After 7 months of treatment, oral cyclophosphamide was stopped due to severe side effects. Case 2: A 58-year-old male presented with an acquired color vision problem in the left eye. He was diagnosed with BSCR in OU. He responded to a clinical trial study for BSCR; however, later, he was diagnosed with npAIR. This patient failed oral cyclophosphamide therapy due to ineffectiveness and side effects. He, subsequently, failed rituximab and bortezomib therapy. Case 3: A 52-year-old female was diagnosed with BSCR. She was successfully treated with mycophenolate mofetil and infliximab for BSCR. She, subsequently, was diagnosed with npAIR, which failed oral cyclophosphamide therapy due to ineffectiveness and side effects and was successfully treated with rituximab and intravenous immunoglobulin infusions. The inclusion of oral cyclophosphamide into the treatment regimen for patients with npAIR secondary to BSCR may raise concerns regarding its safety and efficacy, suggesting the need for careful consideration and evaluation during treatment.","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 1","pages":"92-99"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13043124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe panuveitis - Uncommon presentation of cat scratch disease. 严重的全葡萄膜炎-罕见的猫抓病的表现。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_151_23

Sahel-Akmal Che Mohd Hazidi, Abdul-Hadi Rosli, Aidila Jesmin Jabbari

{"title":"Severe panuveitis - Uncommon presentation of cat scratch disease.","authors":"Sahel-Akmal Che Mohd Hazidi, Abdul-Hadi Rosli, Aidila Jesmin Jabbari","doi":"10.4103/ojo.ojo_151_23","DOIUrl":"10.4103/ojo.ojo_151_23","url":null,"abstract":"Cat scratch disease (CSD) is a systemic infectious illness caused by the Bartonella henselae and usually transmitted to humans directly through bites, scratches, or licks. The most common posterior segment ocular complication of B. henselae is neuroretinitis. Also reported in the literature are a few unusual retinal presentations including retinal white spots, retinal vasoproliferative lesions, papillitis, macular hole, vitreal detachment, vitritis, and branch retinal artery and venous occlusions. This case report describes a CSD patient who presented with unilateral severe panuveitis. This case highlights another posterior segment presentation of CSD. A 7-year-old boy presented with reduced vision in the right eye for 3 days following cat scratch over the right conjunctiva and lower lid 1 week before. Visual acuity in the right eye was counting finger and the left eye was 6/6. There was no relative afferent papillary defect. The right conjunctiva was mildly injected with healed scar. The intraocular pressure was normal. There was the presence of grade four anterior chamber cells but no hypopyon seen. The right posterior segment showed the presence of vitritis, hyperaemic optic disc swelling, vasculitis, and retinitis lesion. He underwent intravitreal tapping and vancomycin and ceftazidime injection. Subsequently, trans pars plana vitrectomy was performed due to worsening ocular condition and visual acuity (hand movement). The serology investigation was positive for B. henselae. The patient was treated with systemic and topical antibiotics up to 6 weeks. Systemic steroid was added subsequently after the infection was controlled. Following treatment, the ocular inflammations had resolved. The final visual acuity of the right eye was 6/6. Published articles on severe panuveitis as presentation of CSD are extremely limited. A high index of suspicion will facilitate the diagnosis and management, especially in the patient with a history of cat scratch.","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 1","pages":"114-117"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13043169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147608914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Myelin oligodendrocyte glycoprotein antibody-associated disease presenting with posterior scleritis. 髓鞘少突胶质细胞糖蛋白抗体相关疾病表现为后巩膜炎。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_300_25

Nisreen Al Balushi, Avital Okrent-Smolar, Sachin Kedar

{"title":"Myelin oligodendrocyte glycoprotein antibody-associated disease presenting with posterior scleritis.","authors":"Nisreen Al Balushi, Avital Okrent-Smolar, Sachin Kedar","doi":"10.4103/ojo.ojo_300_25","DOIUrl":"10.4103/ojo.ojo_300_25","url":null,"abstract":"The objective of this article is to describe an unusual presentation of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) with posterior scleritis and optic neuritis. We report the case of a 50-year-old woman who presented with acute visual deterioration, headache, and painful eye movements. Clinical examination revealed profound vision loss, optic disc edema, and posterior scleritis confirmed via B-scan ultrasound. Magnetic resonance imaging demonstrated optic nerve involvement with perineuritis, and myelin oligodendrocyte glycoprotein antibodies were detected. The patient was treated with intravenous methylprednisolone, oral steroid taper, and plasma exchange, leading to gradual vision recovery. At the 4-month follow-up, she regained functional vision with residual visual field deficits. Ancillary testing confirmed bilateral involvement, despite unilateral symptoms. This case highlights a rare manifestation of MOGAD, suggesting possible inflammatory extension into the scleral tissue. Recognizing posterior scleritis as part of the MOGAD spectrum can aid in timely diagnosis and management.","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"19 1","pages":"111-113"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13043157/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe panuveitis - Uncommon presentation of cat scratch disease. 严重的全葡萄膜炎-罕见的猫抓病的表现。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_48_26

Jyotirmay Biswas, Suchitra Pradeep, Anjana Parameswaran

引用次数: 0

Spontaneously arrested primary congenital glaucoma. 自发性先天性青光眼。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_101_24

Priyasha Goel, Julie Pegu, Suneeta Dubey, Monica Gandhi

引用次数: 0

The pull of the macula: Optic disc dragging in large macular coloboma. 黄斑的牵拉：大黄斑结肠的视盘牵拉。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_424_24

Sahana S Karanth, Akansha Shetty, K Vaishna

引用次数: 0

Leber hereditary optic neuropathy triggered by the AstraZeneca coronavirus disease 2019 vaccination. 阿斯利康2019冠状病毒病疫苗引发的Leber遗传性视神经病变。

Oman Journal of Ophthalmology Pub Date : 2026-02-27 eCollection Date: 2026-01-01 DOI: 10.4103/ojo.ojo_431_24

Anan A Aljawi, Nooran Osama Badeeb

引用次数: 0