{"title":"A 2-year longitudinal evaluation of the iStent inject<sup>®</sup> system for open-angle glaucoma in East Asian eyes.","authors":"Ru Jian Jonathan Teoh, Rupini Yogesvaran, Felicia Foo Yuen Cheng, Roslinah Muji","doi":"10.4103/ojo.ojo_223_23","DOIUrl":"10.4103/ojo.ojo_223_23","url":null,"abstract":"<p><strong>Background: </strong>The aim of the study was to assess the midterm efficacy and safety of the iStent glaucoma device in patients with open-angle glaucoma (OAG).</p><p><strong>Materials and methods: </strong>We conducted a retrospective case series of all patients implanted with iStent inject® in OAG. Primary outcomes included intraocular pressure (IOP) and the reduction of antiglaucoma medications. Safety outcomes comprised adverse complications, additional surgeries, and postoperative best-corrected visual acuity (BCVA).</p><p><strong>Results: </strong>Eight eyes from eight patients were included in this series. The mean age was 56.3 ± 17.5 years. Six eyes had primary OAG and two eyes had secondary OAG. The majority of eyes (75%) had mild-to-moderate glaucoma. Five eyes underwent combined surgery, whereas the remaining three eyes underwent a standalone procedure. The mean baseline IOP was 22.9 ± 8.2 mmHg, and the mean IOP at 2 years after the procedure was 13.6 ± 2.8 mmHg. There was a 44.5% (10.2 ± 2.5 mmHg; <i>P</i> = 0.002) IOP reduction over 2 years. There was also a reduction in medication burden from a baseline mean of 3.4 ± 0.7 to 2.0 ± 1.2 (<i>P</i> = 0.17). There was no documented intraoperative adverse complication, whereas one patient required trabeculectomy post iStent for IOP control.</p><p><strong>Conclusion: </strong>iStent inject implantation safely reduced IOP and medication burden up to 24 months postoperative.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 1","pages":"28-32"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fluorescein-free detection of focal leak in a patient with acute central serous chorioretinopathy.","authors":"Sashwanthi Mohan, Geethu Sugathan","doi":"10.4103/ojo.ojo_29_24","DOIUrl":"10.4103/ojo.ojo_29_24","url":null,"abstract":"<p><p>Fundus fluorescein angiography (FFA) is considered the gold standard for identifying focal leaks in central serous chorioretinopathy (CSCR). However, there are situations where FFA cannot be performed, and alternative noninvasive investigations are required to pinpoint area of focal leaks. We present a case of a 36-year-old female patient with bilateral steroid induced acute CSCR with three distinct fluorescein-free signs converging in the same area indicating presence of focal leak.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 1","pages":"48-50"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An acute posterior multifocal placoid pigment epitheliopathy with presumed systemic lupus erythematosus etiology.","authors":"Omer Othman Abdullah","doi":"10.4103/ojo.ojo_188_23","DOIUrl":"10.4103/ojo.ojo_188_23","url":null,"abstract":"<p><p>This case report describes a patient with acute posterior multifocal placoid pigment epitheliopathy, presumed to be the initial manifestation of systemic lupus erythematosus (SLE), who responded to oral immunotherapy. The clinical, hematological, serological, and imaging examinations were carried out on the 28-year-old female who presented with bilateral multifocal central creamy lesions. The imaging modalities' findings and the overall visual improvement led us to diagnose acute posterior multifocal placoid pigmented epitheliopathy. This is the second time SLE has been presented as acute posterior multifocal placoid pigmented epitheliopathy, and before declaring it is idiopathic, we must investigate it thoroughly.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 1","pages":"51-54"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spontaneous resolution of photodynamic therapy-induced acute exudative maculopathy in a patient suffering from polypoidal choroidal vasculopathy: A case report with 3-year follow-up.","authors":"Alexandros Rouvas, Ilias Georgalas, Malvina-Efthimia Tzanidaki, Nikolaos Gouliopoulos","doi":"10.4103/ojo.ojo_85_24","DOIUrl":"10.4103/ojo.ojo_85_24","url":null,"abstract":"<p><p>A 60-year-old woman suffering from polypoidal choroidal vasculopathy (PCV) was treated with photodynamic therapy (PDT). The treatment spot was small (850 µm) and was targeted only against the lesion and not the surrounding vascular network. Three days later, she complained of severe visual impairment and the clinical examination set the diagnosis of PDT-induced acute exudative maculopathy (PAEM). Further examinations 3 days later demonstrated on the one hand that subretinal fluid had regressed, but on the other hand, it was identified that PDT possibly resulted in the activation of two other previously quiescent PCV lesions. No other treatment was applied, and the patient's clinical status was monitored. A new evaluation after 6 weeks, revealed the complete resolution of the exudative phenomena and the significant improvement of vision. Three years later, the condition remains stable. Our report is the first in the literature to describe a case of PAEM following PDT with a small target spot (850 µm), while no other report has demonstrated that PCV-associated PAEM may resolve spontaneously without any treatment. Moreover, the application of PDT was accompanied by the activation of two previously inactive PCV lesions, an adverse effect that has not been previously described.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 1","pages":"61-65"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The conundrum of post-traumatic corneal rupture in a patient with Ehlers-Danlos syndrome.","authors":"Parul Jain, Isha Gupta, Avani Hariani, Gahan Reddy","doi":"10.4103/ojo.ojo_153_24","DOIUrl":"10.4103/ojo.ojo_153_24","url":null,"abstract":"<p><p>To describe the management of post-traumatic Descemet's membrane detachment and intraoperative corneal rupture in a known case of Ehlers-Danlos Syndrome (EDS). A 7-year-old child, a known case of EDS, presented with Descemet's membrane tear in the right eye for which intracameral sulfur hexafluoride (SF<sub>6</sub>) and descemetopexy were done. Intraoperative spontaneous rupture of the cornea was noted during descemetopexy which was managed using cyanoacrylate glue and bandage contact lens. We successfully used cyanoacrylate tissue adhesive glue for sealing of corneal rupture suggesting that it can be considered a treatment option for such cases where there is a lack of tissue strength for suturing.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 1","pages":"58-60"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral peripheral ulcerative keratitis in a child with juvenile idiopathic arthritis.","authors":"Alma Siddiqui, Reena Kumari, Dinesh Kumar Bhagat","doi":"10.4103/ojo.ojo_141_24","DOIUrl":"10.4103/ojo.ojo_141_24","url":null,"abstract":"<p><p>Peripheral ulcerative keratitis (PUK) is characterized by epithelial destructive lesions in the perilimbal cornea causing corneal thinning. It is an inflammatory condition commonly associated with systemic autoimmune disorders and mainly found in middle-aged females. It is a sight threatening entity with potential for severe visual impairment or loss of eye. Recognition of ocular manifestations of PUK is essential especially in the younger age group, as it is difficult to diagnose in a child. We present a unique case of a 13-year-old girl with bilateral PUK and later diagnosed with juvenile idiopathic arthritis. She was started on methotrexate tablets to control the systemic disease and advised continuation of topical cyclosporine eye drops.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 1","pages":"85-87"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Canalicular repair in an infant with a simple modification in implantation technique of a conventional innovative implant for canalicular stenting.","authors":"Vikas Sharma, Ritesh Waghray, Anuradha Singh, Agrima Bhatia, Akanksha Sahu, Nidhi Kalra, Subhasish Patnaik","doi":"10.4103/ojo.ojo_206_24","DOIUrl":"10.4103/ojo.ojo_206_24","url":null,"abstract":"<p><p>Eyelid injuries associated with canalicular rupture may lead to lacrimal drainage obstruction if not repaired in time. Of the various techniques available, monocanalicular stenting is the procedure of choice. However, these stents are not only costly but also their availability is a limitation. Majority literature focuses on innovative techniques to identify the lost medial part of canaliculi. We developed a novel surgical technique for canalicular repair by inserting a 26 gauge plastic sleeve of pediatric Intravenous cannula utilizing 27 gauge metal irrigation cannula as a guiding tool.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 1","pages":"66-69"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contact lens-related keratitis due to an emerging pathogen <i>Alcaligenes faecalis</i>.","authors":"Venugopal Anitha, Avani Soni, Aditya Sanjeev Ghorpade, Meenakshi Ravindran, Uma Rani","doi":"10.4103/ojo.ojo_203_23","DOIUrl":"10.4103/ojo.ojo_203_23","url":null,"abstract":"<p><p>This case report highlights a rare case of contact lens-related keratitis (CLRK) caused by the emerging pathogen <i>Alcaligenes faecalis</i>, which underscores the growing diversity of microorganisms implicated in ocular infections. A 28-year-old female, who had been using yearly disposable contact lenses (CLs) for the past 8 years without prior complications, developed peripheral corneal infiltrates. The infiltrates were attributed to the chronic use of CLs. Corneal scraping and CL culture results identified <i>A. faecalis</i> as the causative organism, a rare and novel cause of keratitis in CL users. The patient was treated promptly with broad-spectrum topical antibiotics, leading to a full resolution of the infiltrates. This is likely the first documented case of CLRK caused by <i>A. faecalis</i>. While <i>A. faecalis</i> belongs to the Pseudomonadaceae family, it did not manifest as a typical aggressive infection, suggesting a potentially less virulent course in CLRK. This case adds to the growing awareness of nonconventional pathogens in ocular infections and highlights the importance of early detection and treatment to prevent more severe outcomes.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 1","pages":"81-84"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925364/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optical coherence tomography findings in patients with diabetic macular edema: A retrospective analysis.","authors":"Manjunathan Sivarasu, Gopinath Madheswaran, Saranya Sachi Balasubramaniam, Chinnasamy Balasubramaniam","doi":"10.4103/ojo.ojo_23_24","DOIUrl":"10.4103/ojo.ojo_23_24","url":null,"abstract":"<p><strong>Background: </strong>Diabetic macular edema (DME) is a leading cause of vision loss in diabetic people. DME can be treated with various medications, including intravitreal injections, laser therapy, and surgery. Early detection and treatment of DME is essential to prevent vision loss. The study aimed to describe patients' demographic and clinical characteristics with DME, optical coherence tomography (OCT) findings, and visual acuity outcomes.</p><p><strong>Methodology: </strong>A retrospective study reviewed case records of patients with DME between 2017 and 2020. Demographic data, clinical characteristics, and examination results were extracted and analyzed using Microsoft Excel (2013). All patients clinically diagnosed with DME underwent assessment by OCT examination. DME was classified based on OCT findings. Statistical significance was observed at <i>P</i> < 0.05.</p><p><strong>Results: </strong>This retrospective study included 213 eyes of 134 patients, of which 77.6% were male and 22.4% were female. Nonproliferative diabetic retinopathy (NPDR) was present in 51.64% of eyes, and PDR was present in 48.36%. Focal, diffuse, and cystoid macular edema was observed in 68, 31, and 65 eyes, respectively. Tractional macular edema was seen in 16 eyes with posterior hyaloid traction, 13 with epiretinal membrane (ERM), and one with both conditions. DME associated with subretinal fluid (SRF) detachment was seen in 8.92% of eyes. The mean (standard deviation) central retinal thickness was 284.5 (28.9), 434.0 (97.5), 426.5 (27.5), 510.5 (14.1), and 465.5 (280.7) μm in focal, diffuse, cystoid, ERM, and SRF, respectively. Increased central retinal thickness was associated with decreased visual acuity (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The findings of this study suggest that DME is a common and visually significant complication of diabetes. The OCT findings can be used to classify DME into different subtypes, which may help to guide treatment decisions. Focal edema was the most common type of DME with the least central retinal thickness. In NPDR, focal macular edema was the most common; in PDR, cystoid edema was the most common. Cystoid edema was the most common type in the subgroup of patients with recurrent DME following anti-vascular endothelial growth factor injection.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 1","pages":"22-27"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}