Nature Physics最新文献_第5页

The actin cortex acts as a mechanical memory of morphology in confined migrating cells 肌动蛋白皮层在受限的迁移细胞中充当形态的机械记忆

IF 18.4 1区物理与天体物理

Nature Physics Pub Date : 2025-08-25 DOI: 10.1038/s41567-025-02980-z

Yohalie Kalukula, Marine Luciano, Gleb Simanov, Guillaume Charras, David B. Brückner, Sylvain Gabriele

{"title":"The actin cortex acts as a mechanical memory of morphology in confined migrating cells","authors":"Yohalie Kalukula, Marine Luciano, Gleb Simanov, Guillaume Charras, David B. Brückner, Sylvain Gabriele","doi":"10.1038/s41567-025-02980-z","DOIUrl":"10.1038/s41567-025-02980-z","url":null,"abstract":"Cell migration in narrow microenvironments occurs in numerous physiological processes. It involves successive cycles of confinement and release that drive important morphological changes. However, it remains unclear whether migrating cells can retain a memory of their past morphological states that could potentially facilitate their navigation through confined spaces. We demonstrate that local geometry governs a switch between two cell morphologies, thereby facilitating cell passage through long and narrow gaps. We combined cell migration assays on standardized microsystems with biophysical modelling and biochemical perturbations to show that migrating cells have a long-term memory of past confinement events. The morphological cell states correlate across transitions through actin cortex remodelling. These findings indicate that mechanical memory in migrating cells plays an active role in their migratory potential in confined environments. Cells often navigate through confined spaces. Now it is shown that cells retain a mechanical memory of previous confinement events, which makes them more efficient at migrating through narrow microenvironments.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"21 9","pages":"1451-1461"},"PeriodicalIF":18.4,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144900285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bloch oscillations of a soliton in a one-dimensional quantum fluid 一维量子流体中孤子的布洛赫振荡

IF 18.4 1区物理与天体物理

Nature Physics Pub Date : 2025-08-22 DOI: 10.1038/s41567-025-02970-1

F. Rabec, G. Chauveau, G. Brochier, S. Nascimbene, J. Dalibard, J. Beugnon

{"title":"Bloch oscillations of a soliton in a one-dimensional quantum fluid","authors":"F. Rabec, G. Chauveau, G. Brochier, S. Nascimbene, J. Dalibard, J. Beugnon","doi":"10.1038/s41567-025-02970-1","DOIUrl":"10.1038/s41567-025-02970-1","url":null,"abstract":"The motion of a quantum system under an external force often challenges classical intuition. A notable example is the dynamics of a single particle in a periodic potential, which undergoes Bloch oscillations under the action of a constant force. Similar oscillations can also occur in one-dimensional quantum fluids without a lattice. The generalization of Bloch oscillations to a weakly bounded ensemble of interacting particles has so far been limited to the experimental study of the two-particle case, where the observed period is halved compared to the single-particle case. In this work, we observe the oscillations of the position of a mesoscopic solitonic wave packet—consisting of approximately 1,000 atoms—in a one-dimensional Bose gas subjected to a constant uniform force and in the absence of a lattice potential. The oscillation period scales inversely with the number of atoms, revealing its collective nature. We demonstrate the role of the phase coherence of the quantum bath in which the wave packet moves and investigate the underlying topology of the associated superfluid currents. Our measurements highlight the periodicity of the dispersion relation of collective excitations in one-dimensional quantum systems. Studies of Bloch oscillations in many-body systems remain limited due to their interaction-induced damping. Now, such oscillations have been observed in a solitonic wave packet of atoms in a Bose gas at the mesoscopic scale.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"21 10","pages":"1541-1547"},"PeriodicalIF":18.4,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144900161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Magnon-polarons in the Fermi–Hubbard model 费米-哈伯德模型中的磁偶极子

IF 18.4 1区物理与天体物理

Nature Physics Pub Date : 2025-08-22 DOI: 10.1038/s41567-025-03004-6

Max L. Prichard, Zengli Ba, Ivan Morera, Benjamin M. Spar, David A. Huse, Eugene Demler, Waseem S. Bakr

{"title":"Magnon-polarons in the Fermi–Hubbard model","authors":"Max L. Prichard, Zengli Ba, Ivan Morera, Benjamin M. Spar, David A. Huse, Eugene Demler, Waseem S. Bakr","doi":"10.1038/s41567-025-03004-6","DOIUrl":"10.1038/s41567-025-03004-6","url":null,"abstract":"The interplay of magnetic excitations and itinerant charge carriers is a ubiquitous phenomenon in strongly correlated electron systems. A key theoretical question is understanding the renormalization of the magnon quasiparticle, a collective spin excitation, upon doping a magnetic insulator. Here we observe a new type of quasiparticle—a magnon-Fermi-polaron—arising from the dressing of a magnon with the doped holes of a cold-atom Fermi–Hubbard system. Using Raman excitation with controlled momentum in a doped, spin-polarized band insulator, we address the spectroscopic properties of the magnon-polaron. In an undoped system with strong interactions, photoexcitation produces magnons, whose properties are accurately described by spin-wave theory. We measure the evolution of the photoexcitation spectra as we move away from this limit to produce magnon-polarons due to dressing of the magnons by charge excitations. We observe a shift in the polaron energy with doping that is strongly dependent on the injected momentum, accompanied by a reduction of spectral weight in the probed energy window. We anticipate that the technique introduced here, which is the analogue of inelastic neutron scattering, will provide atomic quantum simulators with access to the dynamics of a wide variety of excitations in strongly correlated phases. In strongly correlated systems, how magnetic excitations are renormalized by charge carriers remains an open question. An experiment now reports the observation of magnon-polarons—magnons dressed by doped holes—in a Fermi–Hubbard quantum simulator.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"21 10","pages":"1548-1554"},"PeriodicalIF":18.4,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144901755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extended native gate sets to unlock the performance of quantum processors 扩展原生门集以解锁量子处理器的性能

IF 18.4 1区物理与天体物理

Nature Physics Pub Date : 2025-08-21 DOI: 10.1038/s41567-025-02991-w

引用次数: 0

Universal quantum gate set for Gottesman–Kitaev–Preskill logical qubits 为Gottesman-Kitaev-Preskill逻辑量子比特设置的通用量子门

IF 18.4 1区物理与天体物理

Nature Physics Pub Date : 2025-08-21 DOI: 10.1038/s41567-025-03002-8

V. G. Matsos, C. H. Valahu, M. J. Millican, T. Navickas, X. C. Kolesnikow, M. J. Biercuk, T. R. Tan

{"title":"Universal quantum gate set for Gottesman–Kitaev–Preskill logical qubits","authors":"V. G. Matsos, C. H. Valahu, M. J. Millican, T. Navickas, X. C. Kolesnikow, M. J. Biercuk, T. R. Tan","doi":"10.1038/s41567-025-03002-8","DOIUrl":"10.1038/s41567-025-03002-8","url":null,"abstract":"Conventional approaches towards creating a large-scale, fault-tolerant quantum computer require an error correction scheme that uses multiple physical qubits to encode one logical qubit of protected quantum information. A key limiting factor in realizing error-corrected quantum information processing is the large ratio of physical-to-logical qubits required by many error correction codes, outstripping the size of near-term devices. The Gottesman–Kitaev–Preskill (GKP) code offers hardware efficiency at the cost of increased encoding complexity by encoding a logical qubit into a single quantum harmonic oscillator. Building on earlier demonstrations of GKP-encoded operations, we realize an entangling gate on GKP logical qubits. Our experiments use an optimal control strategy that deterministically implements a universal set of energy-preserving logical gates on finite-energy GKP states encoded in the mechanical motions of a trapped ion. We also directly generate a GKP Bell state starting from vacuum. Our approach is compatible with existing hardware architectures, demonstrating the potential for optimal control techniques with advanced encoding schemes to accelerate the path towards large-scale fault-tolerant quantum information processing. There are many quantum systems that act as high-quality quantum harmonic oscillators, and they can be used to store quantum information using the Gottesman–Kitaev–Preskill code. Entangling gates have now been demonstrated between two of these qubits.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"21 10","pages":"1664-1669"},"PeriodicalIF":18.4,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41567-025-03002-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantum logic with bosonic error correction 具有玻色子纠错的量子逻辑

IF 18.4 1区物理与天体物理

Nature Physics Pub Date : 2025-08-21 DOI: 10.1038/s41567-025-03011-7

Zhubing Jia

引用次数: 0

Optical signatures of interlayer electron coherence in a bilayer semiconductor 双层半导体层间电子相干性的光学特征

IF 18.4 1区物理与天体物理

Nature Physics Pub Date : 2025-08-20 DOI: 10.1038/s41567-025-02971-0

Xiaoling Liu, Nadine Leisgang, Pavel E. Dolgirev, Alexander A. Zibrov, Jiho Sung, Jue Wang, Takashi Taniguchi, Kenji Watanabe, Valentin Walther, Hongkun Park, Eugene Demler, Philip Kim, Mikhail D. Lukin

{"title":"Optical signatures of interlayer electron coherence in a bilayer semiconductor","authors":"Xiaoling Liu, Nadine Leisgang, Pavel E. Dolgirev, Alexander A. Zibrov, Jiho Sung, Jue Wang, Takashi Taniguchi, Kenji Watanabe, Valentin Walther, Hongkun Park, Eugene Demler, Philip Kim, Mikhail D. Lukin","doi":"10.1038/s41567-025-02971-0","DOIUrl":"10.1038/s41567-025-02971-0","url":null,"abstract":"Emergent strongly correlated electronic phenomena in atomically thin transition-metal dichalcogenides are an exciting frontier in condensed matter physics, with examples ranging from bilayer superconductivity and electronic Wigner crystals to the ongoing search for exciton condensation. Here we take a step towards the latter by reporting experimental signatures of unconventional hybridization of the excitons with opposing dipoles consistent with coherence between interlayer electrons in a transition-metal dichalcogenide bilayer. We investigate naturally grown MoS2 homobilayers integrated in a dual-gate device structure allowing independent control of the electron density and out-of-plane electric field. By electron doping the bilayer when electron tunnelling between the layers is negligible, we observe that the two interlayer excitons hybridize, displaying unusual behaviour distinct from both conventional level crossing and anti-crossing. We show that these observations can be explained by quasi-static random coupling between the excitons, which increases with electron density and decreases with temperature. We argue that this phenomenon is indicative of a spatially fluctuating order parameter in the form of interlayer electron coherence, a theoretically predicted many-body state that has yet to be unambiguously established experimentally outside of the quantum Hall regime. Condensates of excitons have been observed in the quantum Hall regime, but evidence for their existence at low magnetic fields remains controversial. Now evidence of coherence between optically pumped interlayer excitons in MoS2 marks a step towards confirming exciton condensation at low magnetic fields.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"21 10","pages":"1563-1569"},"PeriodicalIF":18.4,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41567-025-02971-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145284986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evasive condensate caught by fingerprints 被指纹捕获的逃逸冷凝水

IF 18.4 1区物理与天体物理

Nature Physics Pub Date : 2025-08-20 DOI: 10.1038/s41567-025-03017-1

Harley Scammell

引用次数: 0

Image-guided treatment of mouse tumours with radioactive ion beams 放射性离子束图像引导治疗小鼠肿瘤

IF 18.4 1区物理与天体物理

Nature Physics Pub Date : 2025-08-19 DOI: 10.1038/s41567-025-02993-8

Daria Boscolo, Giulio Lovatti, Olga Sokol, Tamara Vitacchio, Martina Moglioni, Francesco Evangelista, Emma Haettner, Walter Tinganelli, Christian Graeff, Uli Weber, Christoph Schuy, Munetaka Nitta, Daria Kostyleva, Sivaji Purushothaman, Peter G. Thirolf, Andreas Bückner, Jonathan Bortfeldt, Christoph Scheidenberger, Katia Parodi, Marco Durante

{"title":"Image-guided treatment of mouse tumours with radioactive ion beams","authors":"Daria Boscolo, Giulio Lovatti, Olga Sokol, Tamara Vitacchio, Martina Moglioni, Francesco Evangelista, Emma Haettner, Walter Tinganelli, Christian Graeff, Uli Weber, Christoph Schuy, Munetaka Nitta, Daria Kostyleva, Sivaji Purushothaman, Peter G. Thirolf, Andreas Bückner, Jonathan Bortfeldt, Christoph Scheidenberger, Katia Parodi, Marco Durante","doi":"10.1038/s41567-025-02993-8","DOIUrl":"10.1038/s41567-025-02993-8","url":null,"abstract":"Charged particle therapy with protons or heavier ions is one of the most effective radiotherapy techniques, but uncertainties in the beam range can limit its efficacy. Radioactive ion beams are ideal for image-guided particle therapy because isotopes that undergo β+ decay can be visualized with positron emission tomography. This allows spatial localization of the particle distribution in vivo, which can be correlated with the expected dose deposition for online beam range verification. Here we report the successful treatment of a mouse osteosarcoma using a radioactive 11C-ion beam. The tumour was located in the neck, close to the spinal cord, where deviations of even a few millimetres in the beam range could lead to unintended dose deposition in the spine and radiation-induced myelopathy, an injury to the spinal cord. We achieved complete tumour control with the highest dose of 20 Gy while avoiding paralysis. Low-grade neurological side effects were correlated to the activity measured by positron emission tomography in the spine. The biological washout of the activity from the tumour volume was dependent on the dose, indicating a potential component of vascular damage at high doses. This experiment marks a step towards future clinical applications of radioactive ion beams. Particle therapy is subject to uncertainties in the range of the beam. In this study, tumours in the necks of mice were treated with radioactive ion beams, which enabled real-time verification of the beam range.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"21 10","pages":"1648-1656"},"PeriodicalIF":18.4,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41567-025-02993-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145285002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Magnon-polaritons dance around exceptional points 磁非极化子围绕特殊点跳舞

IF 18.4 1区物理与天体物理

Nature Physics Pub Date : 2025-08-19 DOI: 10.1038/s41567-025-02999-2

Changhao Meng, Zhenghua An

引用次数: 0