Nanotechnology最新文献_第8页

The therapeutic potential of reduced graphene oxide in attenuating cuprizone-induced demyelination in mice. 还原氧化石墨烯在减轻铜绿素诱导的小鼠脱髓鞘方面的治疗潜力。

IF 2.9 4区材料科学

Nanotechnology Pub Date : 2024-10-21 DOI: 10.1088/1361-6528/ad857e

Cintia Rizoli, Nathalia Medina Dos Santos, Mário Roberto Maróstica Júnior, Maria Alice da Cruz-Höfling, Monique Culturato Padilha Mendonça, Marcelo Bispo de Jesus

{"title":"The therapeutic potential of reduced graphene oxide in attenuating cuprizone-induced demyelination in mice.","authors":"Cintia Rizoli, Nathalia Medina Dos Santos, Mário Roberto Maróstica Júnior, Maria Alice da Cruz-Höfling, Monique Culturato Padilha Mendonça, Marcelo Bispo de Jesus","doi":"10.1088/1361-6528/ad857e","DOIUrl":"10.1088/1361-6528/ad857e","url":null,"abstract":"Reduced graphene oxide (rGO) has unique physicochemical properties that make it suitable for therapeutic applications in neurodegenerative scenarios. This study investigates the therapeutic potential of rGO in a cuprizone-induced demyelination model in mice through histomorphological techniques and analysis of biochemical parameters. We demonstrate that daily intraperitoneal administration of rGO (1 mg ml-1) for 21 days tends to reduce demyelination in theCorpus callosumby decreasing glial cell recruitment during the repair mechanism. Additionally, rGO interferes with oxidative stress markers in the brain and liver indicating potential neuroprotective effects in the central nervous system. No significant damage to vital organs was observed, suggesting that multiple doses could be used safely. However, further long-term investigations are needed to understand rGO distribution, metabolism, routes of action and associated challenges in central neurodegenerative therapies. Overall, these findings contribute to the comprehension of rGO effectsin vivo, paving the way for possible future clinical research.","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of sulphur in resistive switching behavior of natural rubber-based memory. 硫在天然橡胶记忆体电阻开关行为中的作用。

IF 2.9 4区材料科学

Nanotechnology Pub Date : 2024-10-18 DOI: 10.1088/1361-6528/ad8890

Muhammad Awais, Nadras Othman, Mohamad Danial Shafiq, Feng Zhao, Kuan Yew Cheong

{"title":"Role of sulphur in resistive switching behavior of natural rubber-based memory.","authors":"Muhammad Awais, Nadras Othman, Mohamad Danial Shafiq, Feng Zhao, Kuan Yew Cheong","doi":"10.1088/1361-6528/ad8890","DOIUrl":"https://doi.org/10.1088/1361-6528/ad8890","url":null,"abstract":"The rising environmental awareness has spurred the extensive use of green materials in electronic applications, with bio-organic materials emerging as attractive alternatives to inorganic and organic materials due to their natural biocompatibility, biodegradability, and eco-friendliness. This study showcases the natural rubber based resistive switching memory devices and how varying sulphur concentrations (0 - 0.8 wt.%) in natural rubber thin films impact the resistive switching characteristics. The natural rubber was formulated and processed into a thin film deposited on an ITO substrate as the bottom electrode and with an Ag film as the top electrode. The addition of sulphur modifies the degree of crosslinking in the natural rubber thin film, from which the concentration of -C=C- group and density of defect site (S+) are affected, and hence the resistive switching behavior of the memory device. The devices exhibit bipolar resistance with symmetric switching characteristics which are attributed to the formation of conductive paths facilitate by electron transport along -C=C- and S+ defect sites between the two electrodes. Notably, a sample with 0.2 wt.% sulphur exhibits a high ON/OFF ratio (104), a large memory window (5.5 V), prolonged data retention (10 years), and reliable endurance (120 cycles). These findings highlight the potential of natural rubber as a promising material for eco-friendly resistive-switching random access memory applications.&#xD.","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142470543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reliable fabrication of 3D freestanding nanostructures via all dry stacking of incompatible photoresist. 通过不相容光刻胶的全干式堆叠，可靠地制造出独立的三维纳米结构。

IF 2.9 4区材料科学

Nanotechnology Pub Date : 2024-10-18 DOI: 10.1088/1361-6528/ad8359

Zhiwen Shu, Huikang Liang, Lei Chen, Qing Liu, Pei Zeng, Yuting Zhou, Quan Wang, Fu Fan, Yu Zhou, Yiqin Chen, Bo Feng, Huigao Duan

{"title":"Reliable fabrication of 3D freestanding nanostructures via all dry stacking of incompatible photoresist.","authors":"Zhiwen Shu, Huikang Liang, Lei Chen, Qing Liu, Pei Zeng, Yuting Zhou, Quan Wang, Fu Fan, Yu Zhou, Yiqin Chen, Bo Feng, Huigao Duan","doi":"10.1088/1361-6528/ad8359","DOIUrl":"https://doi.org/10.1088/1361-6528/ad8359","url":null,"abstract":"Three-dimensional (3D) free-standing nanostructures based on electron-beam lithography (EBL) have potential applications in many fields with extremely high patterning resolution and design flexibility with direct writing. In numerous EBL processes designed for the creation of 3D structures, the multilayer resist system is pivotal due to its adaptability in design. Nevertheless, the compatibility of solvents between different layers of resists often restricts the variety of feasible multilayer combinations. This paper introduces an innovative approach to address the bottleneck issue by presenting a novel concept of multilayer resist dry stacking, which is facilitated by a near-zero adhesion strategy. The poly(methyl methacrylate) (PMMA) film is stacked onto the hydrogen silsesquioxane (HSQ) resist using a dry peel and release technique, effectively circumventing the issue of HSQ solubilization by PMMA solvents typically encountered during conventional spin-coating procedures. Simultaneously, a dry lift-off technique can be implemented by eschewing the use of organic solvents during the wet process. This pioneering method enables the fabrication of high-resolution 3D free-standing plasmonic nanostructures and intricate 3D free-standing nanostructures. Finally, this study presents a compelling proof of concept, showcasing the integration of 3D free-standing nanostructures, fabricated via the described technique, into the realm of Fabry-Perot cavity resonators, thereby highlighting their potential for practical applications. This approach is a promising candidate for arbitrary 3D free-standing nanostructure fabrication, which has potential applications in nanoplasmonics, nanoelectronics, and nanophotonics.","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":"36 2","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142470547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RABV antigenic peptide loaded polymeric nanoparticle production, characterization, and preliminary investigation of its biological activity. RABV 抗原肽负载聚合物纳米粒子的生产、表征及其生物活性的初步研究。

IF 2.9 4区材料科学

Nanotechnology Pub Date : 2024-10-18 DOI: 10.1088/1361-6528/ad84fe

Kübra Bezir, Pelin Pelit Arayici, Buşra Akgül, Emrah Şefik Abamor, Serap Acar

{"title":"RABV antigenic peptide loaded polymeric nanoparticle production, characterization, and preliminary investigation of its biological activity.","authors":"Kübra Bezir, Pelin Pelit Arayici, Buşra Akgül, Emrah Şefik Abamor, Serap Acar","doi":"10.1088/1361-6528/ad84fe","DOIUrl":"10.1088/1361-6528/ad84fe","url":null,"abstract":"Nanoparticle-based antigen carrier systems have become a significant area of research with the advancement of nanotechnology. Biodegradable polymers have emerged as particularly promising carrier vehicles due to their ability to address the limitations of existing vaccine systems. In this study, we successfully encapsulated the G5-24 linear peptide, located between amino acids 253 and 275 in the primary sequence of the rabies virus G protein, into biodegradable and biocompatible PLGA copolymer using the double emulsion solvent evaporation method. The resulting nanoparticles had a size of approximately 230.9 ± 0.9074 nm, with a PDI value of 0.168 ± 0.017 and a zeta potential value of -9.86 ± 0.132 mV. SEM images confirmed that the synthesized nanoparticles were uniform in size and distribution. Additionally, FTIR spectra indicated successful peptide loading into the nanoparticles. The encapsulation efficiency of the peptide-loaded nanoparticles was 73.3%, with a peptide loading capacity of 48.2% and a reaction yield of 30.4%. Peptide release studies demonstrated that 65.55% of the peptide was released in a controlled manner over 28 d, following a 'biphasic burst release' profile consistent with the degradation profile of PLGA. This controlled release is particularly beneficial for vaccine studies. Cytotoxicity tests revealed that the R-NP formulation did not induce cytotoxicity in fibroblast cells and enhanced NO production in macrophages, indicating its potential for vaccine development.","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heat transfer origin of adhesion behaviors between liquid-aluminum and solid aluminum/silicon interfaces. 液态铝和固态铝/硅界面之间粘附行为的传热起源。

IF 2.9 4区材料科学

Nanotechnology Pub Date : 2024-10-17 DOI: 10.1088/1361-6528/ad8581

Yun Dong, Weibin Hui, Yusong Ding, Fangming Lian, Lianjia Yan

引用次数: 0

Simulating graphene-based single-electron transistor: incoherent current effects due to the presence of electron-electron interaction. 模拟基于石墨烯的单电子晶体管：电子-电子相互作用导致的非相干电流效应。

IF 2.9 4区材料科学

Nanotechnology Pub Date : 2024-10-17 DOI: 10.1088/1361-6528/ad83da

Washington F Dos Santos, Felippe Amorim, Alexandre Reily Rocha

引用次数: 0

PTFE-based antistatic coatings by incorporating modified carbon black. 掺入改性炭黑的聚四氟乙烯基抗静电涂层。

IF 2.9 4区材料科学

Nanotechnology Pub Date : 2024-10-17 DOI: 10.1088/1361-6528/ad84fd

Pan Xue, Zhen Chen, Linfeng Wei, Xiaogang Hu, Longshi Qiu, Junshuai Li

引用次数: 0

Formation of the hard-magnetic epsilon iron oxide phase from akaganéite nanoparticles. 从阿卡冈奈石纳米颗粒中形成硬磁ε氧化铁相。

IF 2.9 4区材料科学

Nanotechnology Pub Date : 2024-10-17 DOI: 10.1088/1361-6528/ad844f

Navya Joseph, Surya Gopi, Aladin Ullrich, Manfred Albrecht, Senoy Thomas

引用次数: 0

Artificial synapses based on HfO_x/TiO_ymemristor devices for neuromorphic applications. 基于 HfOx/TiOy Memristor 器件的人工突触，用于神经形态应用。

IF 2.9 4区材料科学

Nanotechnology Pub Date : 2024-10-17 DOI: 10.1088/1361-6528/ad857f

Bünyamin Özkal, Nora Ali Abdo Saleh Al-Jawfi, Gökhan Ekinci, Bulat Z Rameev, Rustam I Khaibullin, Sinan Kazan

{"title":"Artificial synapses based on HfOx/TiOymemristor devices for neuromorphic applications.","authors":"Bünyamin Özkal, Nora Ali Abdo Saleh Al-Jawfi, Gökhan Ekinci, Bulat Z Rameev, Rustam I Khaibullin, Sinan Kazan","doi":"10.1088/1361-6528/ad857f","DOIUrl":"10.1088/1361-6528/ad857f","url":null,"abstract":"As a result of enormous progress in nanoscale electronics, interest in artificial intelligence (AI) supported systems has also increased greatly. These systems are typically designed to process computationally intensive data. Parallel processing neural network architectures are particularly noteworthy for their ability to process dense data at high speeds, making them suitable candidates for AI algorithms. Due to their ability to combine processing and memory functions in a single device, memristors offer a significant advantage over other electronic platforms in terms of area scaling efficiency and energy savings. In this study, single-layer and bilayer metal-oxide HfOxand TiOymemristor devices inspired by biological synapses were fabricated by pulsed laser and magnetron sputtering deposition techniques in high vacuum with different oxide thicknesses. The structural and electrical properties of the fabricated devices were analysed using x-ray reflectivity, x-ray photoelectron spectroscopy, and standard two-probe electrical characterization measurements. The stoichiometry and degree of oxidation of the elements in the oxide material for each thin film were determined. Moreover, the switching characteristics of the metal oxide upper layer in bilayer devices indicated its potential as a selective layer for synapse. The devices successfully maintained the previous conductivity values, and the conductivity increased after each pulse and reached its maximum value. Furthermore, the study successfully observed synaptic behaviours with long-term potentiation, long-term depression (LTD), paired-pulse facilitation, and spike-timing-dependent plasticity, showcasing potential of the devices for neuromorphic computing applications.","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanoarchitectonics of tunable aminosalicylate sodium encapsulated gold nanoparticles enabling multi-faceted role as capping, reducing, stabilizing and colorimetric detection of metal ions. 可调氨基水杨酸钠封装金纳米粒子的纳米结构，可在金属离子的封盖、还原、稳定和比色检测等方面发挥多重作用。

IF 2.9 4区材料科学

Nanotechnology Pub Date : 2024-10-16 DOI: 10.1088/1361-6528/ad82f2

Nabojit Das, Akash Kumar, Raja Gopal Rayavarapu

{"title":"Nanoarchitectonics of tunable aminosalicylate sodium encapsulated gold nanoparticles enabling multi-faceted role as capping, reducing, stabilizing and colorimetric detection of metal ions.","authors":"Nabojit Das, Akash Kumar, Raja Gopal Rayavarapu","doi":"10.1088/1361-6528/ad82f2","DOIUrl":"10.1088/1361-6528/ad82f2","url":null,"abstract":"Despite all the advancements in aqueous synthesis of gold nanoparticles, certain features like one-pot/one-step method with minimal reactants using greener solvents are still demanding. The challenge in the aqueous phase synthesis is to balance the nucleation and precise growth of nanoparticles avoiding aggregation. In this work, we report a unique versatile unexplored molecule aminosalicylate sodium (Na-4-ASA) which functions as a capping, reducing, stabilizing and more interestingly as an encapsulating agent for gold nanoparticles. This multi-faceted molecule showed excellent control in synthesizing monodisperse tunable encapsulated nanoparticles of sizes (60 nm, 53 nm and 12 nm) exhibiting absorbance bands at 560 nm, 540 nm and 520 nm respectively. X-ray diffraction and Fourier Transmission Infra-Red validated crystalline structure and binding of Na-4-ASA onto gold nanoparticles surface respectively. Furthermore, the AuNPs were investigated for their ability to detect metal ions through colorimetric change where purification via centrifugation turned out to be a key parameter in enabling the detection. Selectivity towards Al3+was observed with the 12 nm sized nanoparticles at 0.5 ppm metal ion concentration. The AuNPs of sizes 60 nm and 53 nm detected Al3+/Cr3+/Fe3+and Al3+/Fe3+respectively indicating the impact of size in heavy metal ions detection. The greater the size of AuNPs, lower is the selectivity where detection of three metal ions were observed and vice versa i.e. smaller-sized AuNPs showed high selectivity by detecting single metal ion. Also, the time duration for detection increased with decreasing size of the AuNPs. Finally, LOD for the heavy metal ions Al3+, Cr3+, and Fe3+were calculated as 67 ppb, 78 ppb, 76 ppb respectively.","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142372365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0