NanotechnologyPub Date : 2025-08-04DOI: 10.1088/1361-6528/adf2b0
Shantanu Saha, Shrivatch Sankar, Shamsul Arafin
{"title":"Recent advances on neutron-irradiated point defects in h-BN for quantum applications.","authors":"Shantanu Saha, Shrivatch Sankar, Shamsul Arafin","doi":"10.1088/1361-6528/adf2b0","DOIUrl":"10.1088/1361-6528/adf2b0","url":null,"abstract":"<p><p>Two dimensional layered hexagonal boron nitride (h-BN) has recently emerged as a promising quantum material for quantum information science and engineering primarily due to its excellent chemo-mechanical stability and efficacy in hosting quantum point defects (QPDs). These QPDs potentially act as spin based quantum devices and systems which exhibit valuable quantum properties, making them highly sought after in quantum research. This mini-review focuses on the recent progress of neutron irradiated h-BN, the resulting QPDs, and how they function as spin-based quantum sensors. We also outline the key technical challenges associated with the development of high performance quantum devices as well as the improvements needed to enhance quantum properties in such neutron irradiated h-BN. Our review is expected to accelerate further research on neutron irradiation of h-BN for quantum applications and drive interest in the deterministic creation of spin-based quantum emitters.</p>","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144691046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NanotechnologyPub Date : 2025-08-04DOI: 10.1088/1361-6528/adf33e
Yingjie Fan, Ya Wang, Haiteng Huang, Jingjing Zhang, Lihui Yu, Jingquan Guo, Qiutong Zhao, Yiling Zhang, Zhuzhuoyue Chen, Shujun Ye
{"title":"Controllable formation of HfO<sub>2</sub>thin film in 20 nm thick lateral trenches with high aspect ratio up to 30.","authors":"Yingjie Fan, Ya Wang, Haiteng Huang, Jingjing Zhang, Lihui Yu, Jingquan Guo, Qiutong Zhao, Yiling Zhang, Zhuzhuoyue Chen, Shujun Ye","doi":"10.1088/1361-6528/adf33e","DOIUrl":"10.1088/1361-6528/adf33e","url":null,"abstract":"<p><p>Ultimate-vertical-gate-all-around (UVGAA) MOSFET represent an advanced evolution of VGAA architectures, featuring source-drain symmetry enabled by simultaneous formation of both terminals. Derived from the fabrication methods of three dimensional (3D) NAND flash memory, UVGAA MOSFET offer potential for vertically stacked logic circuits. However, their implementation demands ultra-thin sacrificial Si<sub>3</sub>N<sub>4</sub>layers and higher lateral-high-aspect-ratio (LHAR) trench structures compared to 3D NAND flash memory. In this study, 20 nm thick multilayer LHAR trench structures with aspect ratio up to 30 were successfully fabricated via a combined dry and wet etching approach applied to SiO<sub>2</sub>-Si<sub>3</sub>N<sub>4</sub>-SiO<sub>2</sub>multilayer stacks. Hafnium dioxide (HfO<sub>2</sub>) thin films were subsequently deposited within these confined geometries and on planar silicon surfaces using atomic layer deposition. By systematically optimizing key process parameters: precursor pulse time and purge duration-optimal conditions for uniform and conformal film growth were established. The comprehensive deposition behavior of HfO<sub>2</sub>films in different geometric structures has been qualitatively analyzed using the molecular diffusion theory and the surface adsorption kinetics model. Resulting HfO<sub>2</sub>films exhibited predominantly amorphous structure, ultra-low surface roughness, and excellent electrical properties. This study establishes a theoretical framework and process foundation for the miniaturization and performance optimization of next-generation 3D integrated circuits.</p>","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NanotechnologyPub Date : 2025-07-29DOI: 10.1088/1361-6528/adf561
Binghua Long, Jingjing Zhang, Hairui Deng, Xu Sun, Yuguang Lu, Xiaoqing Lin, Abdul Wahab, Han Zhang, Muhammad Zubair Iqbal, Xiangdong Kong
{"title":"Self-Assembled Ag2S-Au Janus Nanoparticles for Targeted Photo-Responsive Thermal Ablation of Cancer Cells and Bacteria.","authors":"Binghua Long, Jingjing Zhang, Hairui Deng, Xu Sun, Yuguang Lu, Xiaoqing Lin, Abdul Wahab, Han Zhang, Muhammad Zubair Iqbal, Xiangdong Kong","doi":"10.1088/1361-6528/adf561","DOIUrl":"https://doi.org/10.1088/1361-6528/adf561","url":null,"abstract":"<p><p>Janus nanoparticles (JNPs) represent one of the most complex nanoparticles, and achieving precise control over their synthesis remains a significant challenge. Here, we explore gold-silver sulfide (Au-Ag₂S) JNPs for targeted anticancer and antibacterial therapies. Au-Ag₂S JNPs were synthesized and characterized using TEM, HRTEM, XRD, EDS, and XPS, confirming their distinct dimeric structure with Au and Ag₂S components. Surface modification with DSPE-PEG and folic acid (FA) enhanced stability and enabled targeted delivery to cancer cells, resulting in AADF JNPs. AADF JNPs exhibited strong NIR-II emission, ideal for in vivo imaging and photothermal therapy (PTT). In vitro studies demonstrated high biocompatibility and enhanced cellular uptake in 4T1 cancer cells compared to non-targeted JNPs. Upon laser irradiation, AADF JNPs effectively reduced 4T1 cell viability, demonstrating their phototherapeutic effect. Furthermore, AADF JNPs exhibited potent antibacterial activity against Escherichia coli and Staphylococcus aureus under NIR irradiation, it achieved 78% tumor cell killing and 99% bacterial eradication. These findings highlight the potential of AADF JNPs as a promising solution for targeted cancer and bacterial infection treatments.</p>","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144743080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NanotechnologyPub Date : 2025-07-28DOI: 10.1088/1361-6528/adf4ef
Yuxi Huang, Chuanzhi Liu, Fan Yang, Jian Liang, James James Cardwell Crabbe, Guicai Song, Zuobin Wang
{"title":"Detecting and classifying the mechanics of cancer and non-cancer cells by machine learning algorithm.","authors":"Yuxi Huang, Chuanzhi Liu, Fan Yang, Jian Liang, James James Cardwell Crabbe, Guicai Song, Zuobin Wang","doi":"10.1088/1361-6528/adf4ef","DOIUrl":"https://doi.org/10.1088/1361-6528/adf4ef","url":null,"abstract":"<p><p>The global burden of cancer has increased in recent years, posing a major public health challenge. Generally, cancer cells are mutate from normal cells and have distinctive mechanical specifications. Despite significant progress in precision medicine, accurately distinguishing cancer cells remains challenging due to the inherent complexities in characterizing single-cell surface properties. In this study, we utilized atomic force microscopy (AFM) to obtain the mechanical properties of hepatic cells, hepatoma cells, gastric cells, and gastric cancer cells. Then, machine learning techniques were used to identify and classify the cancer and non-cancer cells through AFM-based mechanical characteristics. After computational training, the accuracy of classification and screening of four kinds of cells reached 98%, with an area under the receiver operating characteristic curve (AUC-ROC) value of 97.98%. Consequently, we successfully identified digestive system cancer cells and highlighted the valuable role of digital pathology in tumor cell diagnosis. This study provides an objective basis and a new research method for the diagnosis of hepatic cancer and gastric cancer, enriching the tumor cell detection scheme.</p>","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NanotechnologyPub Date : 2025-07-24DOI: 10.1088/1361-6528/ade5fb
Yang Deng, Weihao Zhai, Chongyang Fu, Qizheng Li, Yanqiang Li, Huaisong Zhao, Xiaoxiong Wang
{"title":"Underwater<i>in-situ</i>low-frequency vibration sensor based on oriented electrospinning.","authors":"Yang Deng, Weihao Zhai, Chongyang Fu, Qizheng Li, Yanqiang Li, Huaisong Zhao, Xiaoxiong Wang","doi":"10.1088/1361-6528/ade5fb","DOIUrl":"https://doi.org/10.1088/1361-6528/ade5fb","url":null,"abstract":"<p><p>With the increasing importance of low-frequency signals in underwater monitoring, earthquake early warning, environmental noise analysis, and biomedical imaging, traditional sensor technologies face challenges such as limited flexibility, slow response time, and poor adaptability. Although existing sensors, such as electromagnetic, piezoelectric, and capacitive sensors, have made progress in certain areas, their applications are often restricted by complex environments. This paper innovatively proposes an<i>in-situ</i>vibration monitoring method, designing a low-frequency<i>in-situ</i>detection system based on triboelectric nanogenerator technology. The system not only enables efficient low-frequency signal detection in complex underwater environments but also, by incorporating machine learning algorithms, identifies different signal sources, achieving accurate distinction of intrinsic signals. The application of this technology realizes the concept of<i>in-situ</i>detection, breaking through the limitations of traditional sensor systems and providing a new solution for real-time monitoring of low-frequency signals.</p>","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":"36 30","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhanced ferroptosis by light-triggered biomimetic nano-erythrocyte membranes for tumor synergistic therapy.","authors":"Gaojian Liu, Wenjing Wen, Xuan Zhao, Yanan Jing, Hao Li, Xulong Fan, ZiXuan Huang, Gaofeng Liang","doi":"10.1088/1361-6528/ade1de","DOIUrl":"https://doi.org/10.1088/1361-6528/ade1de","url":null,"abstract":"<p><p>Breast cancer is the most prevalent fatal cancer among women worldwide and the leading cause of death for women. Ferroptosis is a form of programmed cell death that relies on iron and is non-apoptotic, triggered by the inhibition of the cellular antioxidant system. Photodynamic therapy (PDT) employs photosensitizers to produce reactive oxygen species (ROS), increasing oxidative stress in tumor cells. When combined with ferroptosis, PDT can work synergistically to regulate intracellular redox balance. In this study, we designed engineered nano-erythrocyte membranes for targeted delivery of Chlorin e6 (Ce6) and cisplatin (DDP) to enhance breast cancer treatment. By using mild ultrasound, Ce6 and DDP were co-loaded onto the nano-erythrocyte membranes, combining ferroptosis inducers and photosensitizers to combat breast cancer. To improve targeting capability towards breast cancer, RGD cyclic peptides were modified onto the nano-erythrocyte membranes through a thiol-maleimide coupling reaction. The RGD-modified nano-erythrocyte membranes co-loaded with Ce6 and DDP not only inherited the good stability and significant biocompatibility of red blood cell membranes but also promoted the uptake by breast cancer cells, effectively inducing ferroptosis in these cells. In conclusion, this multifunctional 'natural' nanodrug delivery system provides an effective and safe method for PDT combined with ferroptosis for breast cancer treatment.</p>","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":"36 30","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144691047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NanotechnologyPub Date : 2025-07-22DOI: 10.1088/1361-6528/aded95
Buğçe Aydın, Serdar Bozoğlu, Nilgün Karatepe, Fatma Seniha Güner
{"title":"Folic acid-conjugated magnetic carbon nanotube nanocarriers for targeted delivery of mitoxantrone.","authors":"Buğçe Aydın, Serdar Bozoğlu, Nilgün Karatepe, Fatma Seniha Güner","doi":"10.1088/1361-6528/aded95","DOIUrl":"10.1088/1361-6528/aded95","url":null,"abstract":"<p><p>Dual or multi-targeted delivery systems are a crucial aspect of optimal cancer treatment. These systems minimize side effects while maximizing therapeutic efficiency. With this motivation, in this study, we developed a dual-targeted nanocarrier system by modifying bovine serum albumin-coated magnetic carbon nanotubes (mCNT-BSA) with folic acid (FA) to enhance both magnetic and receptor-mediated targeting. The novel carrier was characterized using Fourier transform infrared spectroscopy, scanning electron microscopy-energy dispersive x-ray spectroscopy, x-ray photoelectron spectroscopy, vibrating sample magnetometer, and thermogravimetric analysis. Results confirmed successful FA conjugation and sufficient magnetic properties (14.7 emu g<sup>-1</sup>) for external guidance. The system demonstrated a high mitoxantrone (MTO) loading capacity (120<i>µ</i>g mg<sup>-1</sup>) and pH-sensitive release behavior, supporting drug release in acidic tumor microenvironments.<i>In vitro</i>cytotoxicity assays showed reduced toxicity of mCNT-BSA-FA/MTO on the MDA-MB-231 cancer cell line to free MTO. These findings suggest that mCNT-BSA-FA is a promising nanocarrier system for dual-targeted and controlled MTO delivery.</p>","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NanotechnologyPub Date : 2025-07-21DOI: 10.1088/1361-6528/adee29
Jiale Lv, Dongliang Jia, Pei Yin, Dan Tan
{"title":"Tailoring optoelectronic properties of TMDs through atomic-scale solid-liquid interface engineering.","authors":"Jiale Lv, Dongliang Jia, Pei Yin, Dan Tan","doi":"10.1088/1361-6528/adee29","DOIUrl":"10.1088/1361-6528/adee29","url":null,"abstract":"<p><p>Transition metal dichalcogenides hold immense promise in photoelectrochemical applications, yet the atomic-scale electron transfer dynamics at their aqueous interfaces remain elusive. Here, we systematically investigate the underlying physical principles for MoS<sub>2</sub>, MoSe<sub>2</sub>, and MoTe<sub>2</sub>contact with water using first-principles calculations. Our calculations reveal that interfacial charge transfer occurs exclusively between surface atoms and adjacent water molecules, with the directionality governed by the relative work functions and the external pressure from water. This interfacial charge redistribution triggers band gap narrowing through conduction band downshift, directly modulating the optical responses. In-depth evaluation of joint density of states and critical points reveal that aqueous contact induces new characteristic peaks, broadening the high-intensity region. These findings advance the fundamental understanding of solid-liquid interfacial electrochemistry and establish a theoretical framework for semiconductor-based interfacial electron transfer. Moreover, our work highlights the feasibility of tailoring optical properties at the atomic scale through precise solid-liquid interface engineering, offering transformative insights for next-generation optoelectronic devices.</p>","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144608906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NanotechnologyPub Date : 2025-07-21DOI: 10.1088/1361-6528/aded97
Shuangjia Weng, Xinyu Wang, Hao Zhou, Kangwen He, Chi Chen, Xiaoxiao Lu
{"title":"Nickel-doped Sb<sub>4</sub>O<sub>5</sub>Cl<sub>2</sub>enables bifunctional electrochemical systems for efficient energy storage and saline water treatment.","authors":"Shuangjia Weng, Xinyu Wang, Hao Zhou, Kangwen He, Chi Chen, Xiaoxiao Lu","doi":"10.1088/1361-6528/aded97","DOIUrl":"10.1088/1361-6528/aded97","url":null,"abstract":"<p><p>Aqueous chloride-ion batteries have emerged as promising dual-functional electrochemical systems, offering simultaneous energy storage and desalination capabilities along with inherent environmental and economic benefits. Although Sb<sub>4</sub>O<sub>5</sub>Cl<sub>2</sub>-based anodes operate at favorable low potentials that help mitigate electrode dissolution, their practical application is hindered by limited cycling stability and suboptimal charge efficiency. In this work, we propose a nickel doping strategy that simultaneously enhances the structural stability and chloride-ion storage capacity of Sb<sub>4</sub>O<sub>5</sub>Cl<sub>2</sub>in aqueous electrochemical systems. The optimized sample exhibits outstanding chloride storage performances, delivering a specific capacity of 74.19 mAh g<sup>-1</sup>at 0.3 A g<sup>-1</sup>against an Ag counter electrode, while retaining 85% of its capacity after 200 cycles. When integrated into a hybrid desalination system utilizing a Prussian blue electrode, it delivers an impressive initial desalination capacity of 107.42 mg g<sup>-1</sup>at 1.2 V, maintaining 62.6% capacity retention after 30 cycles. This work proposes a defect chemistry strategy for developing stable, multifunctional electrodes with both energy storage and water purification functionalities, offering a promising material solution for sustainable and integrated resource management.</p>","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NanotechnologyPub Date : 2025-07-18DOI: 10.1088/1361-6528/aded96
Shuhua Tu, Xinli Lou, Jie Feng
{"title":"Stable perovskite quantum dots encapsulated with polymethyl methacrylate microspheres used in 3D printing and white light emitting diodes.","authors":"Shuhua Tu, Xinli Lou, Jie Feng","doi":"10.1088/1361-6528/aded96","DOIUrl":"10.1088/1361-6528/aded96","url":null,"abstract":"<p><p>Perovskite quantum dots (PQDs) have excellent optoelectronic properties such as high quantum yield, narrow emission spectrum, and tunable wavelength. They are widely used in display, LED devices, photovoltaics and photo-detection, etc. However, due to the instability of PQDs, they are easily decomposed by humidity or water, which greatly hinders the practical application. To solve this issue, CsPbX<sub>3</sub>(X: Cl<sup>-</sup>, Br<sup>-</sup>, I<sup>-</sup>) PQDs encapsulated by polymethyl methacrylate (PMMA) microspheres were prepared by the swelling-shrinkage method. The CsPbBr<sub>3</sub>PQDs@PMMA composite microspheres maintain high luminescence intensity and photoluminescence quantum yield after 30 d in water. The fluorescence lifetime of CsPbBr<sub>3</sub>PQDs@PMMA can reach 31.36 ns and the quantum efficiency reached 55.67%. CsPbX<sub>3</sub>PQDs@PMMA microspheres with different colors can be obtained by changing the molar ratio of halogens. The stability of CsPbBr<sub>3</sub>PQDs@PMMA microspheres in air and water were investigated in details. The red, blue and green powders are encapsulated into LED devices with color coordinates of (0.3450, 0.3624), which is close to the ideal white light. The fluorescent powder can also be used in 3D printing fields.</p>","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}