Nanoscale Advances最新文献_第4页

Single-particle tracking of polymer aggregates inside disordered porous media. 无序多孔介质中聚合物聚集体的单粒子跟踪。

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2025-01-08 eCollection Date: 2025-01-28 DOI: 10.1039/d4na00873a

Yusaku Abe, Naoki Tomioka, Yu Matsuda

引用次数: 0

Pre-validation of a novel reconstructed skin equivalent model for skin irritation and nanoparticle risk assessment. 一种用于皮肤刺激和纳米颗粒风险评估的新型重建皮肤等效模型的预验证。

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2025-01-08 DOI: 10.1039/d4na00804a

Priscila Laviola Sanches, Rosana Bizon Vieira Carias, Gutember Gomes Alves, Carolina Motter Catarino, Bruna Bosquetti, Meg Cristina De Castilho Costa, Andrezza Di Pietro Micali, Desirée Cigaran Schuck, José Mauro Granjeiro, Ana R Ribeiro

{"title":"Pre-validation of a novel reconstructed skin equivalent model for skin irritation and nanoparticle risk assessment.","authors":"Priscila Laviola Sanches, Rosana Bizon Vieira Carias, Gutember Gomes Alves, Carolina Motter Catarino, Bruna Bosquetti, Meg Cristina De Castilho Costa, Andrezza Di Pietro Micali, Desirée Cigaran Schuck, José Mauro Granjeiro, Ana R Ribeiro","doi":"10.1039/d4na00804a","DOIUrl":"10.1039/d4na00804a","url":null,"abstract":"In alignment with the global movement toward reducing animal testing, several reconstructed human epidermis (RHE) models have been created for conducting skin irritation tests. These models have undergone development, verification, validation, and integration into OECD TG 439. Our team has introduced a novel in-house RHE named GB-RHE, and we adhere to OECD TG 439 to pre-validate the model and test its potential employment for nanoparticle irritation studies. GB-RHE exhibits morphological, biochemical, and physiological attributes equivalent to the human epidermis, featuring well-differentiated multilayered viable keratinocytes with a robust barrier function. The performance of the GB-RHE model was evaluated using ten reference chemicals, following the performance standard of OECD TG 439. The results demonstrated commendable predictive capacity and showed that titanium dioxide nanoparticles (TiO2 NPs) are 'non-irritant' to the human epidermis following the globally harmonized classification system. However, although the histological analysis did not show morphological changes, transmission electron micrographs demonstrated that TiO2 NPs can be internalized, reaching the external viable layers of the epidermis. This study demonstrates that in addition to the potential of the GB-RHE model to evaluate skin irritation, this model also has the potential to evaluate the skin toxicity of NPs and carry out cell internalization studies.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11744681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143008666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Highly selective ethanol gas sensor based on CdS/Ti₃C₂T _x MXene composites.

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2025-01-08 DOI: 10.1039/d4na00927d

Ly Tan Nhiem, Jianbin Mao, Qui Thanh Hoai Ta, Soonmin Seo

{"title":"Highly selective ethanol gas sensor based on CdS/Ti3C2T x MXene composites.","authors":"Ly Tan Nhiem, Jianbin Mao, Qui Thanh Hoai Ta, Soonmin Seo","doi":"10.1039/d4na00927d","DOIUrl":"10.1039/d4na00927d","url":null,"abstract":"Sensing of hazardous gases has an important role in ensuring safety in a variety of industries as well as environments. Mainly produced by the combustion of fossil fuels and other organic matter, ethanol is a dangerous gas that endangers human health and the environment. Stability and sensing sensitivity are major considerations when designing gas sensors. Here, a superior ethanol sensor with a high response and fast recovery was synthesized by \"wrapping\" CdS nanoparticles on metallic Ti3C2T x MXene using a simple method. CdS nanoparticles were uniformly covered on the Ti3C2T x MXene surface, forming a \"rice crust\"-like heterostructure. The sensor displayed good detection of ethanol gas at room temperature. Response signals up to 31% were obtained for ethanol molecules (20 ppm) with quick recovery (41 s). The performance of the ethanol sensor was evaluated across a range of concentrations (5-100 ppm) and relative humidity (60% and 90% RH) at room temperature. Our method could open up a new strategy for the development of ethanol sensors.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Excitonic circular dichroism in boron-nitrogen cluster decorated graphene.

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2025-01-06 DOI: 10.1039/d4na00759j

Shneha Biswas, Souren Adhikary, Sudipta Dutta

引用次数: 0

High-porosity Pt-CeO₂ nanosponges as oxidation catalyst. 高孔隙率Pt-CeO2纳米海绵作为氧化催化剂。

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2024-12-30 DOI: 10.1039/d4na00525b

Simon Falkner, Carina B Maliakkal, Mareike Liebertseder, Joachim Czechowsky, Maria Casapu, Jan-Dierk Grunwaldt, Christian Kübel, Claus Feldmann

{"title":"High-porosity Pt-CeO2 nanosponges as oxidation catalyst.","authors":"Simon Falkner, Carina B Maliakkal, Mareike Liebertseder, Joachim Czechowsky, Maria Casapu, Jan-Dierk Grunwaldt, Christian Kübel, Claus Feldmann","doi":"10.1039/d4na00525b","DOIUrl":"https://doi.org/10.1039/d4na00525b","url":null,"abstract":"Pt-CeO2 nanosponges (1 wt% Pt) with high surface area (113 m2 g-1), high pore volume (0.08 cm3 g-1) and small-sized Pt nanoparticles (1.8 ± 0.4 nm) are prepared by thermal decomposition of a cerium oxalate precursor and examined for catalytic oxidation of CO, volatile organic compounds (VOCs), and NH3. The cerium oxalate precursor Ce2(C2O4)3·10H2O is prepared by aqueous precipitation from Ce(NO3)3·6H2O and K2C2O4·H2O and thermally converted to CeO2 nanosponges by heating in air. Optimal conditions for decomposition in terms of surface area and porosity are observed at 350 °C for 20 min. Finally, the CeO2 nanosponges are decorated with small-sized Pt nanoparticles, using a wet-chemical impregnation with Pt(ac)2 in methanol. Electron microscopy with tomography, electron spectroscopy and further methods (TG, XRD, FT-IR, sorption analysis) are used to characterize the catalyst composition and especially the structure and porosity of the Pt-CeO2 nanosponges as well as the uniform distribution of the Pt nanoparticles. The Pt-CeO2 nanosponges show good thermal stability (up to 400 °C) and, already as a new, non-optimized catalyst, promising activity for catalytic oxidation of CO, VOCs, NH3 as indicated by high activities in terms of low and stable light-out and light-off temperatures as well as a high selectivity to N2 (for NH3 oxidation) with >80% at 170-250 °C.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142951829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photocatalytic CO₂ reduction of Ag/Ag₂S/Ti₃C₂T _X heterojunctions with enhanced interfacial charge transfer. 增强界面电荷转移的Ag/Ag2S/ ti3c2tx异质结光催化CO2还原

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2024-12-30 DOI: 10.1039/d4na00969j

Bo Zhang, Yijun Chen, Fei Li, Yang Zhang, Xiang Li, Wuwan Xiong, Weili Dai

{"title":"Photocatalytic CO2 reduction of Ag/Ag2S/Ti3C2T X heterojunctions with enhanced interfacial charge transfer.","authors":"Bo Zhang, Yijun Chen, Fei Li, Yang Zhang, Xiang Li, Wuwan Xiong, Weili Dai","doi":"10.1039/d4na00969j","DOIUrl":"10.1039/d4na00969j","url":null,"abstract":"Photocatalytic reduction of CO2 to produce organic fuels is a promising strategy for addressing carbon reduction and energy scarcity. Transition metal carbides (Ti3C2T X ) are of particular interest due to their unique layered structures and excellent electrical conductivity. However, the practical application of Ti3C2T X is limited by the poor separation efficiency of photogenerated charge carriers and the low migration ability of photogenerated electrons. Herein, Ag/Ag2S/Ti3C2T X heterojunctions were synthesized by depositing Ag/Ag2S nanoparticles onto layered Ti3C2T X substrates using a combination of co-precipitation and photoreduction methods. Fluorescence spectra, UV diffuse reflection, and photoelectric chemical characterizations demonstrated that Ag/Ag2S/Ti3C2T X heterojunctions provided effective channels for the reverse and synergistic migration of electrons and holes, leading to improved spatial separation. Notably, the Ag component in the composite acts as an electron acceptor and reactive center, significantly enhancing the migration ability of photogenerated electrons. The total alcohol yield over Ag/Ag2S/Ti3C2T X (125.3 μmol gcatal. -1) was 5.1 times higher than that on Ag2S (24.7 μmol gcatal. -1) and 2.1 times higher than on Ti3C2T X (60.7 μmol gcatal. -1). This study offers valuable insights into designing efficient photocatalytic CO2 reduction catalysts.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11708830/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142951832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bone-derived nanoparticles (BNPs) enhance osteogenic differentiation via Notch signaling. 骨源性纳米颗粒（BNPs）通过Notch信号传导增强成骨分化。

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2024-12-27 eCollection Date: 2025-01-28 DOI: 10.1039/d4na00797b

Austin Stellpflug, Justin Caron, Samantha Fasciano, Bo Wang, Shue Wang

{"title":"Bone-derived nanoparticles (BNPs) enhance osteogenic differentiation via Notch signaling.","authors":"Austin Stellpflug, Justin Caron, Samantha Fasciano, Bo Wang, Shue Wang","doi":"10.1039/d4na00797b","DOIUrl":"10.1039/d4na00797b","url":null,"abstract":"Mesenchymal stem cell (MSC)-based bone tissue regeneration has gained significant attention due to the excellent differentiation capacity and immunomodulatory activity of MSCs. Enhancing osteogenesis regulation is crucial for improving the therapeutic efficacy of MSC-based regeneration. By utilizing the regenerative capacity of bone ECM and the functionality of nanoparticles, we recently engineered bone-based nanoparticles (BNPs) from decellularized porcine bones. The effects of internalization of BNPs on MSC viability, proliferation, and osteogenic differentiation were first investigated and compared at different time points. The phenotypic behaviors, including cell number, proliferation, and differentiation were characterized and compared. By incorporating a LNA/DNA nanobiosensor and MSC live cell imaging, we monitored and compared Notch ligand delta-like 4 (Dll4) expression dynamics in the cytoplasm and nucleus during osteogenic differentiation. Pharmacological interventions are used to inhibit Notch signaling to examine the mechanisms involved. The results suggest that Notch inhibition mediates the osteogenic process, with reduced expression of early and late stage differentiation markers (ALP and calcium mineralization). The internalization of BNPs led to an increase in Dll4 expression, exhibiting a time-dependent pattern that aligned with enhanced cell proliferation and differentiation. Our findings indicate that the observed changes in BNP-treated cells during osteogenic differentiation could be associated with elevated levels of Dll4 mRNA expression. In summary, this study provides new insights into MSC osteogenic differentiation and the molecular mechanisms through which BNPs stimulate this process. The results indicate that BNPs influence osteogenesis by modulating Notch ligand Dll4 expression, demonstrating a potential link between Notch signaling and the proteins present in BNPs.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":"735-747"},"PeriodicalIF":4.6,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11734751/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143008618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Performance enhancement of InSnZnO thin-film transistors by modifying the dielectric-semiconductor interface with colloidal quantum dots. 用胶体量子点修饰介电-半导体界面增强InSnZnO薄膜晶体管的性能。

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2024-12-27 DOI: 10.1039/d4na00967c

Sijie Chen, Haoran Chen, Chenghui Xia, Zhenhua Sun

{"title":"Performance enhancement of InSnZnO thin-film transistors by modifying the dielectric-semiconductor interface with colloidal quantum dots.","authors":"Sijie Chen, Haoran Chen, Chenghui Xia, Zhenhua Sun","doi":"10.1039/d4na00967c","DOIUrl":"10.1039/d4na00967c","url":null,"abstract":"Thin film transistors (TFTs) with InSnZnO (ITZO) and Al2O3 as the semiconductor and dielectric layers, respectively, were investigated, aiming to elevate the device performance. Chemically synthesized CuInS2/ZnS core/shell colloidal quantum dots (QDs) were used to passivate the semiconductor/dielectric interface. Compared with the pristine device, the device with the integrated QDs demonstrates remarkably improved electrical performance, including a higher electron mobility and a lower leakage current. Moreover, the integration of QDs largely mitigates hysteresis in the bidirectional transfer characteristics of the device. Improved negative bias stress stability is also observed in the device with QDs. The performance enhancement is ascribed to the reduction of the trap states induced by the defects in Al2O3, and the screening of electrical dipoles at the Al2O3/ITZO interface. This work proposes a new strategy to passivate the semiconductor/dielectric interface, which not only improves TFT performance, but also holds potential for optoelectronic applications.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11718300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An overview of the use of non-titanium MXenes for photothermal therapy and their combinatorial approaches for cancer treatment. 综述了非钛MXenes光热治疗及其在癌症治疗中的联合应用。

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2024-12-26 DOI: 10.1039/d4na00931b

Fathima Abdul Rahim, K Niyas, Raju Vivek, Soyeb Pathan, P Abdul Rasheed

{"title":"An overview of the use of non-titanium MXenes for photothermal therapy and their combinatorial approaches for cancer treatment.","authors":"Fathima Abdul Rahim, K Niyas, Raju Vivek, Soyeb Pathan, P Abdul Rasheed","doi":"10.1039/d4na00931b","DOIUrl":"10.1039/d4na00931b","url":null,"abstract":"Since the initial publication on the first Ti3C2T x MXene in 2011, there has been a significant increase in the number of reports on applications of MXenes in various domains. MXenes have emerged as highly promising materials for various biomedical applications, including photothermal therapy (PTT), drug delivery, diagnostic imaging, and biosensing, owing to their fascinating conductivity, mechanical strength, biocompatibility and hydrophilicity. Through surface modification, MXenes can mitigate cytotoxicity, enhance biological stability, and improve histocompatibility, thereby enabling their potential use in in vivo biomedical applications. MXenes are also known for their ability to absorb light in the near-infrared (NIR) region and generate heat by localised surface plasmon resonance (LSPR) effects and electron-phonon coupling. Optical excitation laser pulses result in hot photocarrier distribution in MXenes, which quickly transfers surplus energy to the crystal lattice and results in the internal conversion of light into heat with nearly 100% efficiency. The relaxation of hot carrier distribution by electron-phonon interactions leads to the cooling of the lattice by dissipating thermal energy to the surrounding environment. This heating effect of MXenes makes them potential photothermal agents (PTAs), particularly for PTT applications. The adjustable surface of MXenes and their high surface area-to-volume ratios are ideal for the combinatorial approach of PTT along with drug delivery, photodynamic therapy (PDT), bone regeneration and other applications. Since non-Ti MXenes are more biocompatible than Ti MXenes, they are promising candidates for different biomedical applications. This comprehensive review provides a concise overview of the current research patterns, properties, and biomedical applications of non-Ti MXenes, particularly in PTT and its combinatorial approaches.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740912/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143008614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficient counter electrode for quantum dot sensitized solar cells using p-type PbS@reduced graphene oxide composite. p型PbS@reduced氧化石墨烯复合材料用于量子点敏化太阳能电池的高效对电极。

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2024-12-26 eCollection Date: 2025-01-28 DOI: 10.1039/d4na00971a

Huu Phuc Dang, Ha Thanh Tung, Nguyen Thi My Hanh, Nguyen Thuy Kieu Duyen, Vo Thi Ngoc Thuy, Nguyen Thi Hong Anh, Le Van Hieu

{"title":"Efficient counter electrode for quantum dot sensitized solar cells using p-type PbS@reduced graphene oxide composite.","authors":"Huu Phuc Dang, Ha Thanh Tung, Nguyen Thi My Hanh, Nguyen Thuy Kieu Duyen, Vo Thi Ngoc Thuy, Nguyen Thi Hong Anh, Le Van Hieu","doi":"10.1039/d4na00971a","DOIUrl":"10.1039/d4na00971a","url":null,"abstract":"This study developed a novel PbS-rGO composite counter electrode to enhance the performance of quantum dot-sensitized solar cells (QDSSCs). The composite was synthesized via a hydrothermal method by anchoring PbS nanocubes onto reduced graphene oxide (rGO) sheets. The effect of the mass ratio of rGO to PbS (0.0, 0.1, 0.3, and 0.6) on power conversion efficiency (PCE) was investigated. The optimized rGO-PbS (0.03) composite achieved a power conversion efficiency of 5.358%, V oc of 0.540 V, J sc of 21.157 mA cm-2, and FF of 0.516. The rGO framework provides an interconnected conductive network that facilitates efficient charge transport, reduces charge transfer resistance, and improves overall conductivity. Electrochemical analyses confirmed the superior electrocatalytic activity of the composite in reducing the S n 2-/S2- redox couple. The unique band alignment between rGO and PbS optimized the electron transfer pathways. The hierarchical structure increased the surface area and light absorption, enabling a more effective charge transfer at the electrode-electrolyte interface.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":"700-710"},"PeriodicalIF":4.6,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11702035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142951813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0