Nanoscale Advances最新文献

{"title":"Reaction-temperature-dependent shape evolution and optical properties of CsPb(Br/Cl)₃ perovskite nanocrystals.","authors":"Duy Hoang Nguyen, Dong Gwon Heo, Minh Tan Man, Hong Seok Lee","doi":"10.1039/d6na00464d","DOIUrl":"10.1039/d6na00464d","url":null,"abstract":"<p><p>Cesium lead halide perovskites are promising materials for light-emitting diodes (LEDs) due to their tunable band gaps, defect tolerance, and high photoluminescence quantum yields (PLQYs) with narrow emission widths. In particular, mixed-halide CsPb(Br/Cl)₃ nanocrystals (NCs) are promising candidates for true-blue light emission. The properties of these materials are influenced by both their size and composition; however, research on the synthesis conditions related to these two factors is limited. In this work, we systematically investigate the influence of reaction temperature on the morphology and optical properties of CsPb(Br/Cl)₃ NCs synthesized <i>via</i> a hot-injection method. Morphological transformations from nanoplatelets to monodisperse cubic NCs were observed with an increase in reaction temperature. Optical spectroscopy shows a progressive red shift in emission, accompanied by a reduction in the peak linewidth and the Stokes shift. Bandgap energies determined from Tauc analysis strongly correlate with the size of cubic-shaped particles, as described by the Brus quantum confinement model. These results demonstrate that reaction temperature provides an effective strategy for controlling dimensionality, morphology, and excitonic properties of CsPb(Br/Cl)₃ NCs, offering a simple pathway to tailor blue-emitting perovskite nanomaterials for optoelectronic applications.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13532667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148875242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A sulfonic acid-functionalized amine-linked covalent organic framework as a robust catalyst for the preparation of pyrrole-2-ones.","authors":"Mohammadamin Oghan, Mohammad Ali Zolfigol, Maryam Hajjami, Morteza Torabi, Yanlong Gu","doi":"10.1039/d6na00274a","DOIUrl":"10.1039/d6na00274a","url":null,"abstract":"<p><p>In recent years, covalent organic frameworks (COFs) have emerged as powerful heterogeneous catalysts. Notwithstanding, attainment of both crystallinity and stability of COF-based catalysts under harsh conditions is still challenging. Herein, an imine-linked COF has been transformed into an amine-linked COF <i>via</i> the reduction of imine linkages. Amine linkages, due to their stable and irreversible nature, were functionalized with sulfonic acid groups, A-COF/SO₃H, as a highly active catalytic center. X-ray diffraction (XRD) analysis clearly shows that the crystallinity of COF after modification was preserved. Field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM) analyses revealed that A-COF/SO₃H has a plate-like intergrown morphology. The porosity of A-COF/SO₃H was investigated by N₂ adsorption/desorption, indicating a mesoporous structure with a surface area of 93 m² g^-1. To explore the catalytic performance, A-COF/SO₃H was used as an acidic heterogeneous catalyst for the preparation of pyrrole-2-ones. Excellent yield of products, short reaction times and easy work-up are some of the major preferences of this protocol. Moreover, A-COF/SO₃H exhibited good heterogeneity engineering potential and was recovered and reused up to four consecutive cycles without significant loss of its performance.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13531773/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148875249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structure-transport relationships in MXene-based membranes: from synthesis to selective water treatment.","authors":"Salman Khan, Tanvir Khan, Muhammad Naveed, Salman Khan, Ajmal Shah, Naveed Ahmad, Shohreh Azizi, Malik Maaza","doi":"10.1039/d6na00225k","DOIUrl":"10.1039/d6na00225k","url":null,"abstract":"<p><p>Two-dimensional laminar membranes with precisely controlled nanochannels have attracted significant attention for overcoming the permeability selectivity trade-off in water purification. Among them, MXene-based membranes exhibit unique advantages arising from their hydrophilic surfaces, rich surface terminations, and tunable interlayer spacing. This review presents MXene synthesis routes, including direct and <i>in situ</i> etching, hydrothermal processing, and emerging green approaches, with emphasis on their influence on flake morphology, surface chemistry, and stacking behavior. Membrane fabrication strategies, such as vacuum-assisted filtration, mixed-matrix integration, and interlayer engineering, are analyzed to establish correlations between structural features and separation performance. Particular attention is given to transport mechanisms within MXene nanochannels, where size sieving, electrostatic interactions, and confined transport collectively govern ion and molecule selectivity. Recent advances in crosslinking and nanoparticle intercalation are highlighted for effectively suppressing swelling and stabilizing angstrom-scale channels under aqueous conditions. MXene membranes demonstrate high rejection efficiencies with enhanced water permeance and antifouling properties across desalination, heavy metal removal, and organic contaminant separation. The remaining challenges, including scalable fabrication, structural stability, and defect control, are discussed to guide future development toward practical membrane applications.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13532218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148875313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immune-driven biotransformation of gold nanosheets by human primary neutrophils.","authors":"Soumyadeep Poddar, Vishal Nayak, Deeksha Suvarna, Pavithra Kurungottu, Sandeep Shrivastava, Rajendra Kurapati, Srinivasa Reddy Bonam","doi":"10.1039/d6na00592f","DOIUrl":"10.1039/d6na00592f","url":null,"abstract":"<p><p>The presumed chemical inertness of gold nanomaterials underpins their biomedical application, yet their structural fate within the oxidative milieu of innate immune cells remains uncharacterised. Here, we show that sustained engagement of two-dimensional gold nanosheets (AuNS) with primary human neutrophils over 14 days induces progressive crystalline domain disruption and sulfur incorporation within degraded regions, resolved by transmission and scanning electron microscopy with coupled energy-dispersive X-ray analysis. Pharmacological dissection using inhibitors of myeloperoxidase (4-aminobenzoic acid hydrazide, 4-ABAH), NADPH oxidase NOX1/4 (Setanaxib; GKT137831) and 1-methylpropyl 2-imidazolyl disulfide; thioredoxin-1 (PX12) demonstrates that degradation requires convergence of parallel oxidative routes (MPO/HOCl and Fenton-like) with Trx-1-mediated thiol capture of Au⁺ as Au-S-Trx. PX12 abolishes the diagnostic Au-S signature without restoring gold content, whereas simultaneous blockade of all three axes returns gold to near-pristine levels with near-complete nanosheet persistence. Transcriptional profiling further reveals coupling between oxidative burst activity and inflammatory signalling. These findings redefine the biological stability of gold nanostructures under physiologically relevant inflammatory conditions.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13523013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green synthesis of wurtzite ZnO nanoparticles <i>via Indigofera tinctoria</i> stem extract: linking crystallinity with photocatalytic and biological performance.","authors":"Mirza Nusrat Sweety, Shahin Sultana, Md Ashraful Alam, Fariha Chowdhury, Anika Tasnim, Shariful Islam, Asma Shafiq Shathi","doi":"10.1039/d6na00273k","DOIUrl":"10.1039/d6na00273k","url":null,"abstract":"<p><p>The green synthesis of ZnO nanoparticles has been reported through a simplified route using <i>Indigofera tinctoria</i> stem extract, utilised as a bio-reducing agent. ZnO with a hexagonal wurtzite structure and a 35.51 nm crystallite size was confirmed by diffraction peaks in the XRD pattern. The ZnO nanoparticles exhibit a hexagonal single phase (space group <i>P</i>6₃ <i>mc</i>), as determined by a Rietveld refinement study of XRD data. Symmetry between the obtained and observed diffraction patterns is shown by profile parameters (<i>R</i> _p, <i>R</i> _wp, and <i>χ</i> ²) with minimal values. The FTIR spectra showed a strong band at 458 cm^-1 and a small band at 877 cm^-1, attributed to Zn-O and Zn-OH distinctive stretching. SEM images revealed the formation of quasi-spherical ZnO nanoparticles exhibiting an average diameter of ∼36 nm. The TEM image also showed quasi-spherical to hexagonal particle shapes having an average particle size of 36.19 nm. The purity of ZnO nanoparticles was disclosed by the EDX spectrum, which showed the existence of Zn and O elements and the non-existence of peaks related to other elements. The ZnO nanoparticles showed absorption peak maxima at 374 nm with a calculated band gap of 3.21 eV, according to the UV-vis spectra. The zeta potential (<i>ζ</i>) distribution of ZnO nanoparticles was found to range from -54.8077 to +11.9954 mV at pH 7 in aqueous solutions with a hydrodynamic diameter of 129.480 nm. The Raman spectrum supported the presence of crystal defects in the synthesized ZnO. The remarkable MB dye degradation efficiency of ∼93% under sunlight irradiation at 120 minutes was revealed by the photocatalytic experiment's results. After the 5th cycle, the produced ZnO nanoparticles show ∼85% degradation efficiency. Potent antibacterial activities were demonstrated by the green-produced ZnO nanoparticles against both Gram-positive (+) and Gram-negative (-) microorganisms. Additionally, using the DPPH technique, the produced ZnO nanoparticles showed modest antioxidant properties.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13521123/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148840779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly curved and flexible SiO₂ fiber sponge <i>via</i> turbulence spinning for efficient and portable plasma/serum separation.","authors":"Sendong Zhou, Huihe Chen, Zekun Cheng, Yuan Gao, Meng Zhao, Yu Wang, Qingli Xue, Zujing Feng, Shuting Hou, Yuanyuan Zhang, Rui Xu, Yahan Pang, Jianfeng Zhang, Hui Wu, Sen Lin","doi":"10.1039/d6na00366d","DOIUrl":"10.1039/d6na00366d","url":null,"abstract":"<p><p>Blood analysis is essential for managing critically ill patients, yet plasma/serum separation in point-of-care testing (POCT) remains centrifugation-dependent, hindering utility in resource-limited settings. Conventional filtration materials suffer from poor mechanical strength, fragile structures, and suboptimal separation performance. Herein, we fabricate a silica microfiber sponge (Turb-SiO₂) with a 3D disordered network <i>via</i> a turbulence spinning technique. The material exhibits exceptional flexibility, retaining >64% initial stress after 2500 compression cycles, and superior breathability (99.51% air permeability, 0.12 mm H₂O pressure drops) under compression. The Turb-SiO₂ achieves efficient plasma separation with filtrate hemoglobin at 15.7 mg dL^-1, matching centrifugation efficacy and outperforming commercial filters. Its crimped fiber structure minimizes hemolysis by eliminating sharp tips that can damage red blood cells. With advantages in weight, volume, cost and operability, the Turb-SiO₂ offers a high-performance solution for portable low-cost POCT blood separation.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13519913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148840789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hierarchical ZnMn₂O₄@ZnMn₂O₄ nanoflower architectures grown on Ni foam as promising electrodes for high-performance supercapacitors.","authors":"Chandu V V Muralee Gopi, Dasha Kumar Kulurumotlakatla, Ghuzanfar Saeed, R Ramesh","doi":"10.1039/d6na00488a","DOIUrl":"10.1039/d6na00488a","url":null,"abstract":"<p><p>Supercapacitors have been promising electrochemical energy storage systems due to their long cycle life, rapid charge-discharge, and high-power density. However, the performance of supercapacitor devices mainly depends on the electrode material structure and morphology. In this regard, the present study reports a new advanced electrode material, the ZnMn₂O₄@ZnMn₂O₄ architecture, successfully grown on a nickel foam substrate <i>via</i> a facile two-step hydrothermal route without binders or additives. Surface morphology results reveal that the ZnMn₂O₄@ZnMn₂O₄ architecture exhibits a flower-like morphology comprising interconnected nanoplatelet structures. Electrochemical results indicate that the hierarchical ZnMn₂O₄@ZnMn₂O₄ architecture electrode material exhibits pseudocapacitive behavior with improved charge-transfer kinetics and enhanced ion diffusion. The sequentially grown ZnMn₂O₄ structured electrode exhibits a high specific capacitance of 230.34 F g^-1 at 1 mA cm^-2, nearly double that of the bare ZnMn₂O₄ electrode (121.63 F g^-1). Moreover, the ZnMn₂O₄@ZnMn₂O₄ architecture electrode delivers a superior cycling stability of 88.85% over 5000 cycles compared to that of the bare ZnMn₂O₄ electrode (85.96%). Therefore, these findings conclude that the hierarchical architecture with a higher active-material loading of ZnMn₂O₄@ZnMn₂O₄ is a promising electrode material for high-performance supercapacitor applications.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13520214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148840826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Submicron microdevice patterning with plasma-thinned nail-polish microfiber shadow masks.","authors":"Yong Xie, Qianjie Lei, Nuria Jiménez-Arévalo, Esteban Zamora-Amo, Thomas Pucher, Andres Castellanos-Gomez","doi":"10.1039/d6na00537c","DOIUrl":"10.1039/d6na00537c","url":null,"abstract":"<p><p>Access to sub-micrometer electrode patterning remains limited in laboratories without lithographic or specialized mask-fabrication facilities. We present a novel, low-cost method for fabricating microdevices using nail-polish microfibers as shadow masks. A thin fiber is drawn by repeatedly touching a nail-polish droplet with a wire loop and placed directly onto the target substrate to define narrow features for metal deposition. As-drawn fibers reach diameters down to ∼2 µm and conform to both rigid and flexible surfaces. Oxygen-plasma thinning at ∼22 nm min^-1 reduces fibers initially ≥4 µm in diameter to below 1 µm, enabling electrode gaps down to ∼478 nm, as confirmed by atomic force microscopy. The process requires no spin-coated photoresist, baking, or development. Using this approach, we pattern microelectrodes on SiO₂/Si and polycarbonate and realize functional devices, including MoS₂ field-effect transistors, MoS₂ photodetectors, and a flexible device based on chemical vapor deposition-grown MoS₂. The method requires no photolithography, minimizes material cost, and leverages readily available tools and consumables, providing a practical route to prototyping and education as well as laboratory microfabrication.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13539493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced Nb-doped ZnO/ZIF-8 nanocomposite: a synergistic smart strategy for catalytic functionality in preparation of spiro[indene-2,2'-naphthalene]-4-carbonitriles and antibiotic resistance.","authors":"Narjes Sadat Mireei, Pooria Babaei, Somaye Rashki, Aliasghar Mahmoudi Kharazm, Aref Ghasemi-Ghahsareh, Seyyed Mohammad Ebrahimi","doi":"10.1039/d6na00123h","DOIUrl":"10.1039/d6na00123h","url":null,"abstract":"<p><p>In recent decades, the increasing prevalence of antibacterial resistance and the growing global demand for efficient, sustainable catalytic systems have emerged as critical frontiers in pharmaceutical and materials science. This pressing necessity has prompted the development of multifunctional nanocomposites with integrated therapeutic and synthetic capabilities. In this study, a novel Nb-doped ZnO/ZIF-8 hybrid composite was designed and prepared as a synergistic, high-performance dual-purpose nanostructure for broad-spectrum antibacterial and highly efficient catalytic functionality. Structural engineering <i>via</i> niobium doping significantly refined the composite topology, reducing the average crystallite size to 25 nm and optimizing the pore diameter to 9.68 nm (<i>S</i> _BET = 87.35 m² g^-1), thereby maximizing the accessible active sites. Benefiting from enhanced electronic charge separation and the resulting improvement in interfacial electron transfer, the designed composite exhibited robust antibacterial activity against both Gram-negative and Gram-positive bacteria, particularly <i>Staphylococcus aureus</i> and <i>Enterococcus faecalis</i>, with inhibition zones of 18 and 21 mm, respectively, and a 5-log reduction in viability within 24 h. These empirical findings suggest a potent oxidative-stress-inducing mechanism suitable for combating resistant clinical pathogens. Furthermore, the hybrid composite demonstrated exceptional utility as an outstanding heterogeneous catalyst for the preparation of medicinal substituted spiro[indene-2,2'-naphthalene]-4-carbonitrile derivatives in an ethanol medium, achieving excellent yields (up to 98%) within 20 minutes and retaining high catalytic functionality over five consecutive runs without significant leaching. This study highlights the potential of Nb-doped ZnO/ZIF-8 as a robust dual-purpose composite for antimicrobial applications and sustainable catalysis in green organic synthesis, offering a scalable, environmentally benign paradigm for addressing contemporary biomedical and catalytic challenges.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13501467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148813644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A mesoporous silica-based MRI/NIR-II fluorescence bimodal nanoprobe for precision detection and surgical navigation of sentinel lymph node metastasis.","authors":"Renhai Feng, Hui Wang, Siyi Tao, Kuang Xu, Ke Xu, Yongxiao Mou, Zhifa Shen, Jiaxi Ru, Can Shao","doi":"10.1039/d6na00444j","DOIUrl":"10.1039/d6na00444j","url":null,"abstract":"<p><p>Precise detection of sentinel lymph node (SLN) metastasis is critical for accurate cancer staging and effective surgical navigation. In this study, we developed a high-performance magnetic resonance imaging (MRI)/near-infrared (NIR)-II fluorescence imaging nanoplatform by integrating the NIR dye IR820 and the gadolinium-based MRI contrast agent (GdL) into mesoporous silica nanoparticles (MSNs) using bovine serum albumin (BSA) as the functional component. This nanoplatform exhibits strong NIR-II fluorescence tail emission and high longitudinal relaxivity, enabling dual-modality imaging for the diagnosis of primary tumors and metastatic lymph nodes, as well as NIR-II fluorescence-guided surgery (FGS). Within this system, BSA not only serves as a structural stabilizer but also significantly enhances IR820 fluorescence emission and improves GdL relaxivity. Notably, two types of surface-functionalized MSNs, amine- and thiol-modified, were systematically compared, and the thiol-modified MSNs exhibited superior imaging performance, including a red-shifted absorption peak and markedly enhanced NIR-II fluorescence emission. <i>In vitro</i> and <i>in vivo</i> experiments confirmed that the dual-modality nanoprobe accumulated efficiently in tumors and SLNs, enabling high-sensitivity MRI localization and high-resolution NIR-II fluorescence imaging of metastatic lesions. Overall, this study presents a surface-engineering strategy to enhance the imaging performance of MRI/NIR-II nanoprobes, offering a promising approach for accurate diagnosis of lymph node metastasis and real-time FGS.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13539382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}