Nanoscale Advances最新文献

{"title":"Enhancing 3-acetyl-11-keto-β-boswellic acid skin permeation <i>via</i> nanostructured lipid carriers: integrating quality by design principles for risk estimation and optimization.","authors":"Sakshi Priya, Vaibhavi Meghraj Desai, Hemraj Singh, Rajeev Taliyan, Gautam Singhvi","doi":"10.1039/d5na00445d","DOIUrl":"https://doi.org/10.1039/d5na00445d","url":null,"abstract":"<p><p>3-Acetyl-11-keto-β-boswellic acid (AKBA), a bioactive compound derived from <i>Boswellia serrata</i>, exhibits significant anti-inflammatory and antioxidant properties, making it a promising candidate for treating inflammatory skin disorders. Its hydrophobic nature makes topical administration challenging. By developing nanostructured lipid carriers (NLCs), this work sought to enhance the skin penetration of AKBA. Quality-by-design principles were applied for the development of a robust formulation, where AKBA-NLCs were developed using a three-factor, three-level Box-Behnken design. AKBA-NLCs were prepared by the hot homogenization technique. The optimized formulation was further loaded into a gelling system, and its rheological parameters were evaluated. Further evaluation for <i>ex vivo</i> skin permeation and retention, along with other characteristics such as occlusivity, extrudability, and spreadability, was performed. Quality-by-design through <i>p</i>-value assessment highlighted that all three factors significantly affected particle size, and in the case of PDI, only lipid content showed a significant impact, whereas for entrapment efficiency, lipid and surfactant content were the governing factors. Based on the set constraints, the optimized batch of AKBA-NLCs exhibited a particle size of 173.700 ± 1.165 nm, a PDI of 0.323 ± 0.012, a zeta potential of -19.533 ± 0.493 mV, and an entrapment efficiency of 82.349 ± 3.223%. The <i>in vitro</i> release showed a prolonged release profile up to 56 h. When tested for cytotoxicity in the HaCaT cell line, the formulation was observed to be non-cytotoxic. The rheological data of the gel demonstrated a non-Newtonian, pseudo-plastic nature and indicated good structural strength. The <i>ex vivo</i> skin permeation of AKBA-NLCs was found to be 1.34 times higher than that <i>via</i> plain gel. Based on consistent results of viscosity, particle size integrity, and assay after one year of storage, the formulation was found to be stable. The formulation method used was simple and cost-effective, allowing for possible industrial scale-up. According to the findings, the NLC-loaded gel may prove to be a useful delivery strategy for the management of inflammatory skin conditions.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12495300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polydopamine and hyaluronic acid-coated dual-responsive silica nanoparticles for targeted atherosclerosis imaging and therapy.","authors":"Yuanzhe Lin, Chenyuan Huang, Xiao Hou, James Chen Yong Kah, Jiong-Wei Wang","doi":"10.1039/d5na00497g","DOIUrl":"https://doi.org/10.1039/d5na00497g","url":null,"abstract":"<p><p>Atherosclerosis remains the primary cause underlying cardiovascular diseases, however, there is no plaque-targeting pharmacotherapy clinically available. Nebivolol (NB), a third-generation beta-blocker clinically used to treat hypertension and heart failure, exerts potent antioxidative activities by inhibiting reactive oxygen species (ROS) production and scavenging ROS. Here, we developed an atherosclerotic plaque lesional macrophage-targeting nanotheranostic system that is coated with polydopamine (PDA) as a contrast agent to facilitate non-invasive photoacoustic imaging (PAI) of atherosclerotic plaques and NB as a drug to eliminate plaque ROS. In brief, mesoporous silica nanoparticles (MSNs) with interpenetrating chiral channels were coated with bioinspired PDA polymers (SPDA). PDA on the nanoparticle surface was then conjugated with hyaluronic acid (HA) to allow active targeting to atherosclerotic macrophages that overexpress CD44 (SPDA@HA). Upon loading of NB, the resulting NB/SPDA@HA nanoparticles could eliminate ROS and alleviate inflammation in activated macrophages. In addition, NB/SPDA@HA nanoparticles inhibited cell apoptosis and oxidized low density lipoprotein induced foam cell formation. Moreover, the silanols on the silica surface and the HA coating on the MSNs enable accelerated drug release from NB/SPDA@HA nanoparticles in response to the acidic and hyaluronidase-rich microenvironment in the plaque. Taken together, the dual-responsive NB/SPDA@HA nanotheranostic platform represents a promising nanomedicine for targeted atherosclerosis imaging and therapy.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12495310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction: CTL–doxorubicin (DOX)–gold complex nanoparticles (DOX–AuGCs): from synthesis to enhancement of therapeutic effect on liver cancer model","authors":"Qiqian Liu, Hui Liu, Pasquale Sacco, Nadia Djaker, Marc Lamy de la Chapelle, Eleonora Marsich, Xiaowu Li and Jolanda Spadavecchia","doi":"10.1039/D5NA90068A","DOIUrl":"10.1039/D5NA90068A","url":null,"abstract":"<p >Retraction of “CTL–doxorubicin (DOX)–gold complex nanoparticles (DOX–AuGCs): from synthesis to enhancement of therapeutic effect on liver cancer model” by Qiqian Liu <em>et al.</em>, <em>Nanoscale Adv.</em>, 2020, <strong>2</strong>, 5231–5241, https://doi.org/10.1039/D0NA00758G.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" 20","pages":" 6659-6659"},"PeriodicalIF":4.6,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12478200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145200204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nitrogen-doped Cu₄O₃ thin films as high-performance counter electrodes for quantum dot-sensitized solar cells.","authors":"Pham Minh Khang, Le Thanh Duy, Huu Phuc Dang, Tran Le","doi":"10.1039/d5na00664c","DOIUrl":"10.1039/d5na00664c","url":null,"abstract":"<p><p>P-type metal oxide semiconductors are critical components in the development of next-generation optoelectronic and photovoltaic devices. While n-type materials such as SnO₂, ZnO, and ITO are well-established, the lack of stable, high-performance p-type transparent oxides with suitable bandgaps remains a key limitation. Among copper oxides, Cu₄O₃-a mixed-valence oxide-offers promising electronic and optical tunability, yet has been underexplored for device integration. In this work, nitrogen-doped Cu₄O₃ thin films were synthesized <i>via</i> DC magnetron sputtering under an (Ar + 10% O₂)/N₂ atmosphere. The incorporation of nitrogen effectively modulated the electronic structure, enhanced chemical stability, and improved electrical transport properties. The optimal film, denoted as Cu₄O₃-30 (30% N₂), exhibited a direct optical bandgap of 2.18 eV, resistivity of 4.19 Ω cm, hole concentration of 3.33 × 10¹⁷ cm^-3, and hole mobility of 4.48 cm² V^-1 s^-1. When implemented as a counter electrode in TiO₂/CdS/CdSe:Cu/ZnS quantum dot-sensitized solar cells (QDSSCs), the device achieved a power conversion efficiency of 7.29%, exceeding the performance of its Cu₂S-based counterparts. These results highlight the potential of N-doped Cu₄O₃ as a scalable, chemically stable, and electrically efficient p-type oxide for emerging optoelectronic and photovoltaic technologies.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12465014/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surface-enhanced Raman spectroscopy as a tool for food and environmental monitoring of pesticides: recent trends and perspectives.","authors":"Gabriel Fernandes Souza Dos Santos, Giordano Toscano Paganoto, Lucas Carreira Cosme, Adilson Ribeiro Prado, Sérvio Túlio Alves Cassini, Marco César Cunegundes Guimarães, Jairo Pinto de Oliveira","doi":"10.1039/d5na00539f","DOIUrl":"10.1039/d5na00539f","url":null,"abstract":"<p><p>Surface-enhanced Raman spectroscopy (SERS) has emerged as a powerful analytical tool for ultrasensitive detection of environmental contaminants, particularly pesticides. Recent developments have focused on nanomaterials engineering and SERS-active sensors to enhance signal intensity. Gold (AuNPs) and silver nanoparticles (AgNPs) of various morphologies and sizes have been widely explored due to their plasmonic properties, as well as hybrid or combined nanoparticle systems. Innovative approaches have also been developed, such as embedding nanoparticles in gels to enhance stability and reproducibility or using magnetic nanoparticles for sample interaction and preconcentration. Additionally, the integration of graphene oxide has gained attention because of its ability to improve the chemical enhancement mechanism <i>via</i> π-π interactions with analyte molecules. Despite these advances, SERS-based detection remains challenging, particularly with regard to selectivity in complex matrices. To address this issue, recent strategies have combined SERS substrates with biorecognition molecules such as antibodies, aptamers, and enzymes, thereby improving specificity and facilitating the development of SERS-based biosensors. This review highlights the current state-of-the-art SERS applications for pesticide detection in food and environmental samples, discussing the key technological advances, material innovations, and analytical challenges. This paper also offers perspectives on future research directions to increase the sensitivity, reproducibility, and field applicability of SERS-based detection platforms.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic catalytic and antibacterial activity, along with <i>in silico</i> molecular docking of bimetallic silver-copper-doped PVP-Mg(OH)₂ nanostructures.","authors":"Zarqa Altaf, Muhammad Imran, Ali Haider, Iram Shahzadi, Zernab Mateen, Anwar Ul-Hamid, Ahmed M Fouda, Muhammad Ikram","doi":"10.1039/d5na00693g","DOIUrl":"10.1039/d5na00693g","url":null,"abstract":"<p><p>Industrial wastewater treatment is a critical challenge requiring innovative solutions to address global water scarcity. In this work, magnesium hydroxide Mg(OH)₂ nanostructures (NSs) were successfully synthesized <i>via</i> a cost-effective and sustainable co-precipitation approach, doped with 3 wt% polyvinylpyrrolidone (PVP) and varying amounts (2 and 4 wt%) of silver-copper (Ag-Cu). The main purpose of this research was to investigate the ternary system's ability in dye degradation and its antibacterial properties. PVP, as a capping agent, regulates the growth of the NSs and provides stability. The incorporation of Ag-Cu minimizes agglomeration and promotes the formation of a network comprising PVP-capped NSs along with Ag-Cu nanoparticles (NPs). This interconnected network facilitates charge transport, thereby enhancing the overall catalytic performance. The study revealed that 4 wt% Ag-Cu/PVP-Mg(OH)₂ significantly degrades (99.68%) rhodamine B (RhB) in acidic medium as opposed to alkaline and neutral pH levels, and it achieves a maximum inhibition zone of 7.95 ± 0.02 mm against MDR <i>Staphylococcus aureus</i> (<i>S. aureus</i>). The prospective inhibitory mechanism of the synthesized NSs on the DNA gyrase enzyme of <i>S. aureus</i> was explored by molecular docking.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12465013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A simple method to distinguish light scattering from light absorption by nanoparticles.","authors":"Arianna Menichetti, Dario Mordini, Enrico Rampazzo, Agata Pane, Silvia Vicenzi, Vasilis Petropoulos, Giulio Cerullo, Fabrizio Mancin, Marco Montalti","doi":"10.1039/d5na00194c","DOIUrl":"10.1039/d5na00194c","url":null,"abstract":"<p><p>Photothermal efficiencies of natural and biomimetic melanin nanoparticles are compared. In order to justify the different behaviour, a preliminary investigation of the light scattering and light absorption properties of the NPs was performed using a simple new method based on a conventional fluorometer without the use of any integrating sphere.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12459033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145150128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functionalization of lipid nanoemulsions with humanized antibodies using plug-and-play cholesterol anchor for targeting cancer cells.","authors":"Valeria Jose Boide-Trujillo, Vincent Mittelheisser, Fei Liu, Olivier Lefebvre, Bohdan Andreiuk, Nicolas Anton, Jacky G Goetz, Andrey S Klymchenko","doi":"10.1039/d5na00606f","DOIUrl":"https://doi.org/10.1039/d5na00606f","url":null,"abstract":"<p><p>Lipid nanoemulsions (NEs) are promising green nanocarriers for diagnostic and therapeutic applications, but their functionalization with biomolecules, such as antibodies, remains a challenge due to liquid nature of their core. Here, we developed an original plug-and-play strategy to graft an antibody (trastuzumab) at the surface of NEs, using components generally recognized as safe (GRAS). We synthesized a reactive 4-nitrophenyl carbonate of cholesterol (NPC-Chol) and a Biotin-PEG₃₀₀₀-Lysine linker, which can react within one-pot formulation to form an amphiphilic carbamate Biotin-PEG₃₀₀₀-Cholesterol. The cholesterol ensures anchorage of the linker, which effectively exposes biotin moiety at the surface of NEs for further antibody grafting using a biotin-neutravidin coupling. The reaction between the Biotin-PEG₃₀₀₀-Lysine linker and NPC-Chol was confirmed by ¹H-NMR and absorption spectroscopy. The obtained biotinylated 50-nm NEs loaded with a near-infrared dye were successfully targeted to neutravidin-coated glass surfaces and imaged at the single-droplet level. The biotinylated NEs bearing the trastuzumab antibody targeted specifically HER2-amplified breast cancer models HCC-1954 and SKBR3, in contrast to control MDA-MB-231 (HER2-low) cells. Altogether, our study proposes an efficient methodology for grafting antibodies to the surface of NEs, which offers new opportunities of application of these green nanocarriers in biomedicine.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of flexible piezoresistive pressure sensors <i>via</i> direct ink writing of MWCNT/PDMS nanocomposite inks: rheological and electromechanical characterization.","authors":"Jashanpreet Singh Sidhu, Aviral Misra, Arvind Bhardwaj","doi":"10.1039/d5na00796h","DOIUrl":"10.1039/d5na00796h","url":null,"abstract":"<p><p>The integration of nanoscience and 3D printing has given rise to the emerging field of printable and flexible electronics. Direct ink writing (DIW) has transformed the field of 3D printing by using viscoelastic inks, ensuring design, intricacy, and flexibility. This study presents the fabrication of flexible piezoresistive pressure sensors using multiwalled carbon nanotubes (MWCNTs)/polydimethylsiloxane (PDMS) based conductive inks <i>via</i> the DIW method. Three ink formulations were prepared with MWCNT concentrations of 2 wt%, 4 wt%, and 6 wt% to investigate their rheological and printability characteristics. Rheological analysis revealed that MWCNT loading concentrations above 4 wt% impart shear-thinning behavior and solid-like viscoelastic properties essential for DIW printing. Among the formulations, the 6 wt% MWCNT/PDMS ink exhibited the best printability and structural integrity for porous woodpile architectures. Morphological analysis confirmed the dispersion of MWCNTs within the PDMS matrix, indicating an effective filler distribution and network formation throughout the composite. Mechanical testing demonstrated that 6 wt% MWCNT/PDMS exhibited a threefold increase in Young's modulus (3.61 MPa) and a higher tensile strength (2.44 MPa) compared to pristine PDMS, owing to effective stress transfer and nanotube reinforcement. Cyclic tensile fatigue tests confirmed the CNT-6 composite's mechanical stability and low stress softening at lower strains, underscoring its durability for flexible pressure sensor applications. The fabricated pressure sensor demonstrated a pronounced piezoresistive response with a high sensitivity of 0.047 kPa^-1, along with excellent repeatability and stability under both static and dynamic loading conditions, establishing its potential for precision pressure monitoring in flexible and wearable sensing applications.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12447840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green-synthesized ZnO nanoparticles for efficient atrazine detection: electrochemical and computational investigations.","authors":"Simranjeet Singh, Pavithra N, Radhika Varshney, Ashutosh Panchal, Nabila Shehata, Nadeem A Khan, Joginder Singh, Praveen C Ramamurthy","doi":"10.1039/d5na00595g","DOIUrl":"https://doi.org/10.1039/d5na00595g","url":null,"abstract":"<p><p>Developing sustainable and efficient methods for detecting environmental contaminants like atrazine (ATZ) is critical for environmental monitoring. This study uses a green approach to synthesise zinc oxide nanoparticles (g-ZnO NPs), employing an aqueous extract of <i>Haldina cordifolia</i> leaves as a natural reducing and stabilizing agent. The synthesized g-ZnO NPs were characterized using techniques such as XRD, TGA, SEM, UV-Vis spectroscopy, XPS, and FTIR to confirm their crystalline structure, morphology, optical properties, and functional groups. These nanoparticles demonstrated excellent sensitivity for the detection of ATZ, a widely used herbicide, <i>via</i> an electrochemical approach. The molecular docking simulations also predicted a favourable affinity of ZnO towards ATZ <i>via</i> hydrogen bonding. The sensor developed exhibited high selectivity for ATZ detection, achieving an LLOD of 0.41 μg mL^-1 within a linear range of 0.5 to 3 μM. Its practicality was validated in different types of water where the recovery rates ranged from 87.26% to 94.8% in STP water and from 90.52% to 95.66% in DI water, highlighting their reliability in real-world applications. In this study, <i>Haldina cordifolia</i> is being explored for the first time to synthesize g-ZnO NPs, which are then utilized for the electrochemical detection of ATZ. The biosynthetic approach not only provides an eco-friendly route for nanoparticle synthesis but also enhances the potential for rapid and reliable detection of ATZ in water and STP samples.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12495293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}