Light-Science & Applications最新文献_第6页

Polaritons light up future displays 极化子点亮未来显示器

Light-Science & Applications Pub Date : 2024-11-04 DOI: 10.1038/s41377-024-01647-3

Andreas Mischok

引用次数: 0

Color-conversion displays: current status and future outlook 色彩转换显示器：现状与未来展望

Light-Science & Applications Pub Date : 2024-11-01 DOI: 10.1038/s41377-024-01618-8

Guijun Li, Man-Chun Tseng, Yu Chen, Fion Sze-Yan Yeung, Hangyu He, Yuechu Cheng, Junhu Cai, Enguo Chen, Hoi-Sing Kwok

引用次数: 0

Dynamic synthetic-scanning photoacoustic tracking monitors hepatic and renal clearance pathway of exogeneous probes in vivo 动态合成扫描光声跟踪监测体内外源探针的肝脏和肾脏清除途径

Light-Science & Applications Pub Date : 2024-10-31 DOI: 10.1038/s41377-024-01644-6

Jing Lv, Hengrong Lan, Aoji Qin, Tong Sun, Dan Shao, Fei Gao, Junjie Yao, Kamran Avanaki, Liming Nie

{"title":"Dynamic synthetic-scanning photoacoustic tracking monitors hepatic and renal clearance pathway of exogeneous probes in vivo","authors":"Jing Lv, Hengrong Lan, Aoji Qin, Tong Sun, Dan Shao, Fei Gao, Junjie Yao, Kamran Avanaki, Liming Nie","doi":"10.1038/s41377-024-01644-6","DOIUrl":"https://doi.org/10.1038/s41377-024-01644-6","url":null,"abstract":"Advancements in precision medicine necessitate understanding drug clearance pathways, especially in organs like the liver and kidneys. Traditional techniques such as PET/CT pose radiation hazards, whereas optical imaging poses challenges in maintaining both depth penetration and high resolution. Moreover, very few longitudinal studies have been performed for drug candidates for different symptoms. Leveraging non-ionizing photoacoustic tomography for deep tissue imaging, we developed a spatiotemporally resolved clearance pathway tracking (SRCPT) method, providing unprecedented insights into drug clearance dynamics within vital organs. SRCPT addresses challenges like laser fluence attenuation, enabling dynamic visualization of drug clearance pathways and essential parameter extraction. We employed a novel frequency component selection based synthetic aperture focusing technique (FCS-SAFT) with respiratory-artifacts-free weighting factors to enhance three-dimensional imaging resolutions. Inspired by this, we investigated the clearance pathway of a clinical drug, mitoxantrone, revealing reduced liver clearance when hepatic function is impaired. Furthermore, immunoglobulin G clearance analysis revealed significant differences among mice with varying renal injury degrees. The accuracy of our method was validated using a double-labeled probe [68Ga]DFO-IRDye800CW, showing a strong positive correlation between SRCPT and PET. We believe that this powerful SRCPT promises precise mapping of drug clearance pathways and enhances diagnosis and treatment of liver and kidney-related diseases.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142556220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Shape optimization for high efficiency metasurfaces: theory and implementation 高效超表面的形状优化：理论与实施

Light-Science & Applications Pub Date : 2024-10-29 DOI: 10.1038/s41377-024-01629-5

Paulo Dainese, Louis Marra, Davide Cassara, Ary Portes, Jaewon Oh, Jun Yang, Alfonso Palmieri, Janderson Rocha Rodrigues, Ahmed H. Dorrah, Federico Capasso

引用次数: 0

Long-range enhancement for fluorescence and Raman spectroscopy using Ag nanoislands protected with column-structured silica overlayer 使用柱状结构二氧化硅覆盖层保护的银纳米岛实现荧光和拉曼光谱的长程增强

Light-Science & Applications Pub Date : 2024-10-28 DOI: 10.1038/s41377-024-01655-3

Takeo Minamikawa, Reiko Sakaguchi, Yoshinori Harada, Hiroki Tanioka, Sota Inoue, Hideharu Hase, Yasuo Mori, Tetsuro Takamatsu, Yu Yamasaki, Yukihiro Morimoto, Masahiro Kawasaki, Mitsuo Kawasaki

{"title":"Long-range enhancement for fluorescence and Raman spectroscopy using Ag nanoislands protected with column-structured silica overlayer","authors":"Takeo Minamikawa, Reiko Sakaguchi, Yoshinori Harada, Hiroki Tanioka, Sota Inoue, Hideharu Hase, Yasuo Mori, Tetsuro Takamatsu, Yu Yamasaki, Yukihiro Morimoto, Masahiro Kawasaki, Mitsuo Kawasaki","doi":"10.1038/s41377-024-01655-3","DOIUrl":"https://doi.org/10.1038/s41377-024-01655-3","url":null,"abstract":"We demonstrate long-range enhancement of fluorescence and Raman scattering using a dense random array of Ag nanoislands (AgNIs) coated with column-structured silica (CSS) overlayer of over 100 nm thickness, namely, remote plasmonic-like enhancement (RPE). The CSS layer provides physical and chemical protection, reducing the impact between analyte molecules and metal nanostructures. RPE plates are fabricated with high productivity using sputtering and chemical immersion in gold(I)/halide solution. The RPE plate significantly enhances Raman scattering and fluorescence, even without proximity between analyte molecules and metal nanostructures. The maximum enhancement factors are 107-fold for Raman scattering and 102-fold for fluorescence. RPE is successfully applied to enhance fluorescence biosensing of intracellular signalling dynamics in HeLa cells and Raman histological imaging of oesophagus tissues. Our findings present an interesting deviation from the conventional near-field enhancement theory, as they cannot be readily explained within its framework. However, based on the phenomenological aspects we have demonstrated, the observed enhancement is likely associated with the remote resonant coupling between the localised surface plasmon of AgNIs and the molecular transition dipole of the analyte, facilitated through the CSS structure. Although further investigation is warranted to fully understand the underlying mechanisms, the RPE plate offers practical advantages, such as high productivity and biocompatibility, making it a valuable tool for biosensing and biomolecular analysis in chemistry, biology, and medicine. We anticipate that RPE will advance as a versatile analytical tool for enhanced biosensing using Raman and fluorescence analysis in various biological contexts.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142490955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamic control and manipulation of near-fields using direct feedback 利用直接反馈对近场进行动态控制和操纵

Light-Science & Applications Pub Date : 2024-10-24 DOI: 10.1038/s41377-024-01610-2

Jacob Kher-Aldeen, Kobi Cohen, Stav Lotan, Kobi Frischwasser, Bergin Gjonaj, Shai Tsesses, Guy Bartal

{"title":"Dynamic control and manipulation of near-fields using direct feedback","authors":"Jacob Kher-Aldeen, Kobi Cohen, Stav Lotan, Kobi Frischwasser, Bergin Gjonaj, Shai Tsesses, Guy Bartal","doi":"10.1038/s41377-024-01610-2","DOIUrl":"https://doi.org/10.1038/s41377-024-01610-2","url":null,"abstract":"Shaping and controlling electromagnetic fields at the nanoscale is vital for advancing efficient and compact devices used in optical communications, sensing and metrology, as well as for the exploration of fundamental properties of light-matter interaction and optical nonlinearity. Real-time feedback for active control over light can provide a significant advantage in these endeavors, compensating for ever-changing experimental conditions and inherent or accumulated device flaws. Scanning nearfield microscopy, being slow in essence, cannot provide such a real-time feedback that was thus far possible only by scattering-based microscopy. Here, we present active control over nanophotonic near-fields with direct feedback facilitated by real-time near-field imaging. We use far-field wavefront shaping to control nanophotonic patterns in surface waves, demonstrating translation and splitting of near-field focal spots at nanometer-scale precision, active toggling of different near-field angular momenta and correction of patterns damaged by structural defects using feedback enabled by the real-time operation. The ability to simultaneously shape and observe nanophotonic fields can significantly impact various applications such as nanoscale optical manipulation, optical addressing of integrated quantum emitters and near-field adaptive optics.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142488422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structured light analogy of quantum squeezed states 量子挤压态的结构光类比

Light-Science & Applications Pub Date : 2024-10-21 DOI: 10.1038/s41377-024-01631-x

Zhaoyang Wang, Ziyu Zhan, Anton N. Vetlugin, Jun-Yu Ou, Qiang Liu, Yijie Shen, Xing Fu

{"title":"Structured light analogy of quantum squeezed states","authors":"Zhaoyang Wang, Ziyu Zhan, Anton N. Vetlugin, Jun-Yu Ou, Qiang Liu, Yijie Shen, Xing Fu","doi":"10.1038/s41377-024-01631-x","DOIUrl":"https://doi.org/10.1038/s41377-024-01631-x","url":null,"abstract":"Quantum optics has advanced our understanding of the nature of light and enabled applications far beyond what is possible with classical light. The unique capabilities of quantum light have inspired the migration of some conceptual ideas to the realm of classical optics, focusing on replicating and exploiting non-trivial quantum states of discrete-variable systems. Here, we further develop this paradigm by building the analogy of quantum squeezed states using classical structured light. We have found that the mechanism of squeezing, responsible for beating the standard quantum limit in quantum optics, allows for overcoming the “standard spatial limit” in classical optics: the light beam can be “squeezed” along one of the transverse directions in real space (at the expense of its enlargement along the orthogonal direction), where its width becomes smaller than that of the corresponding fundamental Gaussian mode. We show that classical squeezing enables nearly sub-diffraction and superoscillatory light focusing, which is also accompanied by the nanoscale phase gradient of the size in the order of λ/100 (λ/1000), demonstrated in the experiment (simulations). Crucially, the squeezing mechanism allows for continuous tuning of both features by varying the squeezing parameter, thus providing distinctive flexibility for optical microscopy and metrology beyond the diffraction limit and suggesting further exploration of classical analogies of quantum effects.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142451594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Direct phase measurement of waveguides with a next generation optical vector spectrum analyzer 利用下一代光矢量频谱分析仪直接测量波导的相位

Light-Science & Applications Pub Date : 2024-10-19 DOI: 10.1038/s41377-024-01574-3

Andrew Grieco

引用次数: 0

Multi-particle quantum walks on 3D integrated photonic chip 三维集成光子芯片上的多粒子量子行走

Light-Science & Applications Pub Date : 2024-10-19 DOI: 10.1038/s41377-024-01627-7

Wen-Hao Zhou, Xiao-Wei Wang, Ruo-Jing Ren, Yu-Xuan Fu, Yi-Jun Chang, Xiao-Yun Xu, Hao Tang, Xian-Min Jin

{"title":"Multi-particle quantum walks on 3D integrated photonic chip","authors":"Wen-Hao Zhou, Xiao-Wei Wang, Ruo-Jing Ren, Yu-Xuan Fu, Yi-Jun Chang, Xiao-Yun Xu, Hao Tang, Xian-Min Jin","doi":"10.1038/s41377-024-01627-7","DOIUrl":"https://doi.org/10.1038/s41377-024-01627-7","url":null,"abstract":"Quantum walks provide a speed-up in computational power for various quantum algorithms and serve as inspiration for the construction of complex graph representations. Many pioneering works have been dedicated to expanding the experimental state space and the complexity of graphs. However, these experiments are mostly limited to small experimental scale, which do not reach a many-body level and fail to reflect the multi-particle quantum interference effects among non-adjacent modes. Here, we present a quantum walk with three photons on a two-dimensional triangular lattice, which is mapped to a 19 × 19 × 19 high-dimensional state space and constructs a complex graph with 6859 nodes and 45,486 edges. By utilizing the statistical signatures of the output combinations and incorporating machine learning techniques, we successfully validate the nonclassical properties of the experiment. Our implementation provides a paradigm for exponentially expanding the state space and graph complexity of quantum walks, paving the way for surmounting the classical regime in large-scale quantum simulations.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"233 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142449517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

4.8-μm CO-filled hollow-core silica fiber light source 4.8 微米 CO 填充中空芯硅光纤光源

Light-Science & Applications Pub Date : 2024-10-18 DOI: 10.1038/s41377-024-01615-x

Xuanxi Li, Linyong Yang, Zhiyue Zhou, Zhixian Li, Hao Li, Wenxi Pei, Wei Huang, Jing Shi, Luohao Lei, Meng Wang, Zefeng Wang

{"title":"4.8-μm CO-filled hollow-core silica fiber light source","authors":"Xuanxi Li, Linyong Yang, Zhiyue Zhou, Zhixian Li, Hao Li, Wenxi Pei, Wei Huang, Jing Shi, Luohao Lei, Meng Wang, Zefeng Wang","doi":"10.1038/s41377-024-01615-x","DOIUrl":"https://doi.org/10.1038/s41377-024-01615-x","url":null,"abstract":"Mid-infrared (MIR) fiber lasers are important for a wide range of applications in sensing, spectroscopy, imaging, defense, and security. Some progress has been made in the research of MIR fiber lasers based on soft glass fibers, however, the emission range of rare-earth ions and the robustness of the host materials are still a major challenge for MIR fiber lasers. The large number of gases provide a variety of optical transitions in the MIR band. When combined with recent advances in low-loss hollow-core fiber (HCF), there is a great opportunity for gas-filled fiber lasers to further extend the radiation to the MIR region. Here, a 4.8-μm CO-filled silica-based HCF laser is reported for the first time. This is enabled by an in-house manufactured broadband low-loss HCF with a measured loss of 1.81 dB/m at 4.8 μm. A maximum MIR output power of 46 mW and a tuning range of 180 nm (from 4644 to 4824 nm) are obtained by using an advanced 2.33-μm narrow-linewidth fiber laser. This demonstration represents the longest-wavelength silica-based fiber laser to date, while the absorption loss of bulk silica at 4824 nm is up to 13, 000 dB/m. Further wavelength expansion could be achieved by changing the pump absorption line and optimizing the laser structure.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142448314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0